The cerebrocerebellar system
Abstract
If there is a cerebellar contribution to nonmotor function, particularly to cognitive abilities and affective states, then there must be corresponding anatomic substrates that support this. The cerebellum is strongly interconnected with the cerebral hemispheres in both feedforward (cerebral hemispheres to cerebellum) and feedback directions. This relationship has long been recognized, particularly with respect to the motor and sensory cortices. Investigations performed over the last decade however, have demonstrated for the first time the organization and strength of the connections that link the cerebellum with areas of the cerebral cortex known to be concerned with higher order behavior rather than with motor control. The feedforward projections from these higher order areas, namely the associative and paralimbic cortices, seem to be matched, at least in the limited but definite demonstrations to date, by cerebellar projections back to these same areas. These observations are important because they are congruent with the notion that cognitive functions are distributed among multiple cortical and subcortical nodes, each of which functions in concert but in a unique manner to produce an ultimate behavior pattern. This chapter describes the neural circuitry postulated to subserve the cerebellar contribution to nonmotor processing, particularly cognitive and affective modulation, and discusses the theoretical implications of these anatomic findings.
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Support for long-range signals likely involves the cerebellum's closed-loop connections with numerous regions in the cerebral cortex.
“Support for these long-range signals likely involves the cerebellum’s closed-loops connections with numerous regions in the cerebral cortex (for reviews, see Schmahmann and Pandya, 1997; Strick et al., 2009; Bostan et al., 2013; Lena, 2016).”
From Cerebellum, Predictions and Errors (2019) · cites this paper as Schmahmann and Pandya, 1997
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- Authors
- Schmahmann, J. D., & Pandya, D. N.
- Affiliations
- Massachusetts General Hospital (US)
- Venue
- International Review of Neurobiology
- Publisher
- Elsevier
- Published
- 1997
- Volume
- 41
- Pages
- 31-60
- ISSN
- 0074-7742 (ISSN-L)
- OpenAlex
- W1589968137
- Cited by
- 774
- References
- 7
- Citations by year
- 2026: 15 · 2025: 15 · 2024: 17 · 2023: 25 · 2022: 28 · 2021: 18 · 2020: 22 · 2019: 33 · 2018: 29 · 2017: 31 · 2016: 27 · 2015: 31 · 2014: 27 · 2013: 23 · 2012: 29
- FWCI
- 15.44
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- International review of neurobiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- cerebellum, cognitive function, affective states, association cortex, paralimbic cortex, neural circuits
- MeSH terms
- Affect, Animals, Cerebellum, Cerebral Cortex, Cognition, Feedback, Humans, Nerve Fibers
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