The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Isolation of Multipotent Cells from Human Term Placenta
Abstract
Current sources of stem cells include embryonic stem cells (ESCs) and adult stem cells (ASCs). However, concerns exist with either source: ESCs, with their significant ethical considerations, tumorigenicity, and paucity of cell lines; and ASCs, which are possibly more limited in potential. Thus, the search continues for an ethically conducive, easily accessible, and high-yielding source of stem cells. We have isolated a population of multipotent cells from the human term placenta, a temporary organ with fetal contributions that is discarded postpartum. These placenta-derived multipotent cells (PDMCs) exhibit many markers common to mesenchymal stem cells--including CD105/endoglin/SH-2, SH-3, and SH-4--and they lack hematopoietic-, endothelial-, and trophoblastic-specific cell markers. In addition, PDMCs exhibit ESC surface markers of SSEA-4, TRA-1-61, and TRA-1-80. Adipogenic, osteogenic, and neurogenic differentiation were achieved after culturing under the appropriate conditions. PDMCs could provide an ethically uncontroversial and easily accessible source of multipotent cells for future experimental and clinical applications.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Multilineage potential of adult human mesenchymal stem cells
Pittenger, M. F., Mackay, A. M., Beck, S. C., Jaiswal, R. K., Douglas, R., Mosca, J. D., Moorman, M. A., Simonetti, D. W., Craig, S., & Marshak, D. R. (1999) · Science · doi:10.1126/science.284.5411.143 · Cited by 21,052
Comparative Developmental Anatomy of the Murine and Human Definitive Placentae
Georgiades, P., Ferguson-Smith, A. C., & Burton, G. J. (2002) · Placenta · doi:10.1053/plac.2001.0738 · Cited by 641
Cited by
Gandia, C., Armiñan, A., García-Verdugo, J. M., Lledó, E., Ruiz, A., Miñana, M. D., Sanchez-Torrijos, J., Payá, R., Mirabet, V., Carbonell-Uberos, F., et al. (2008) · Stem Cells · doi:10.1634/stemcells.2007-0484 · Cited by 406
Multipotent Stem Cells from Umbilical Cord: Cord Is Richer than Blood!
Secco, M., Zucconi, E., Vieira, N. M., Fogaça, L. L. Q., Cerqueira, A., Carvalho, M. D. F., Jazedje, T., Okamoto, O. K., Muotri, A. R., & Zatz, M. (2008) · Stem Cells · doi:10.1634/stemcells.2007-0381 · Cited by 398
Wu, M., Zhang, R., Zou, Q., Chen, Y., Zhou, M., Li, X., Ran, R., & Chen, Q. (2018) · Scientific Reports · doi:10.1038/s41598-018-23396-1 · Cited by 206
Self-citationStem cells and tissue engineering: past, present, and future
POLAK, J. M., & BISHOP, A. E. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1346.001 · Cited by 155
Metadata
- Authors
- Yen, B. L., Huang, H., Chien, C., Jui, H., Ko, B., Yao, M., Shun, C., Yen, M., Lee, M., & Chen, Y.
- Venue
- STEM CELLS
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-01
- Volume
- 23
- Issue
- 1
- Pages
- 3-9
- ISSN
- 1066-5099 (ISSN-L)
- 1549-4918
- OpenAlex
- W1991328368
- Cited by
- 440
- References
- 2
- FWCI
- 11.68
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Isolation of Multipotent Cells from Human Term Placenta. https://app.cochat.ai/papers/10.1634/stemcells.2004-0098
- The paper
- Yen, B. L., Huang, H., Chien, C., Jui, H., Ko, B., Yao, M., Shun, C., Yen, M., Lee, M., & Chen, Y. (2005). Isolation of Multipotent Cells from Human Term Placenta. STEM CELLS. https://doi.org/10.1634/stemcells.2004-0098
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
