Cited by 45Microbial Metabolites in Food BiotechnologyProbiotics and Fermented FoodsInfant Nutrition and Health

Evaluation of prebiotic effects of high-purity galactooligosaccharides in vitro and in vivo

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Department of Public Health Sciences, Graduate School, Korea University, Seoul 136-713, Republic of Korea, Hong, Ki Bae, Kim, Jae Hwan, Neo Cremar Co. Ltd., Seongnam 462-806, Republic of Korea, Kwon, Hyuk Kon, Neo Cremar Co. Ltd., Seongnam 462-806, Republic of Korea, Han, Sung Hee, Institute for Biomaterials, Korea University, Seoul 136-713, Republic of Korea +4 more·2016·Food Technology and Biotechnology

Abstract

in the gut increased most rapidly up to 12 h, and thereafter the increase was slow. Therefore, 1% HP-GOS was found to be acceptable for the growth of probiotic bacteria. Groups of animals that were orally administered HP-GOS and bifidobacteria during the study, and the group administered HP-GOS during the 2nd (days 13-15) and 4th (days 28-30) period of the study had significantly (p<0.05) higher numbers of bifidobacteria in faeces than groups receiving a single dose of bifidobacteria. HP-GOS affected the expression of genes encoding glucagon-like peptide-1 (GLP-1) and peptide YY (PYY). There was a significant upregulation of GLP-1 and PYY mRNA with HP-GOS and bifidobacteria intake. We propose that the prebiotic properties of HP-GOS are potentially valuable for the production of functional foods for human consumption.

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Crossref · 10.17113/ftb.54.02.16.4292

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33 of 33 references verified0 citation errors · 0 not checkable

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  • PYY expression is upregulated in the ileum after treatment with prebiotic galacto-oligosaccharides.

    “For instance, PYY expression is upregulated in the ileum after treatment with prebiotic galacto-oligosaccharides (GOS) [202].”
  • Hong et al. found an upregulation of intestinal PYY with the commensal bacteria Bifidobacterium bifidum in rats.

    “Hong et al. [202] found an upregulation of intestinal PYY with the commensal bacteria Bifidobacterium bifidum in rats.”

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Authors
Department of Public Health Sciences, G. S., Hong, K. B., Kim, J. H., Neo Cremar Co. Ltd., S. 4.-8., Kwon, H. K., Neo Cremar Co. Ltd., S. 4.-8., Han, S. H., Institute for Biomaterials, K. U., Park, Y., Institute for Biomaterials, K. U., Suh, H. J., & Institute for Biomaterials, K. U.
Affiliations
  • Korea University (KR)
  • Dongguk University (KR)
Corresponding author
Park, Yooheon
Venue
Food Technology and Biotechnology
Published
2016
Volume
54
Issue
2
Pages
156-163
ISSN
  • 1330-9862 (ISSN-L)
  • 1334-2606
OpenAlex
W2469343084
Cited by
45
References
33
Citations by year
2026: 3 · 2025: 2 · 2024: 7 · 2023: 7 · 2022: 8 · 2021: 3 · 2020: 6 · 2019: 4 · 2017: 4 · 2016: 1
FWCI
3.14
Type
journal article
Language
en
Open access
Locations
  • Food Technology and Biotechnology (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • University of Zagreb University Computing Centre (SRCE) (submittedVersion, other-oa)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
Keywords
galactooligosaccharides, prebiotics, Bifidobacterium, glucagon-like peptide-1, peptide YY, gene expression, gut microbiota, functional foods, oral administration

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