Evaluation of prebiotic effects of high-purity galactooligosaccharides in vitro and in vivo
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in the gut increased most rapidly up to 12 h, and thereafter the increase was slow. Therefore, 1% HP-GOS was found to be acceptable for the growth of probiotic bacteria. Groups of animals that were orally administered HP-GOS and bifidobacteria during the study, and the group administered HP-GOS during the 2nd (days 13-15) and 4th (days 28-30) period of the study had significantly (p<0.05) higher numbers of bifidobacteria in faeces than groups receiving a single dose of bifidobacteria. HP-GOS affected the expression of genes encoding glucagon-like peptide-1 (GLP-1) and peptide YY (PYY). There was a significant upregulation of GLP-1 and PYY mRNA with HP-GOS and bifidobacteria intake. We propose that the prebiotic properties of HP-GOS are potentially valuable for the production of functional foods for human consumption.
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PYY expression is upregulated in the ileum after treatment with prebiotic galacto-oligosaccharides.
“For instance, PYY expression is upregulated in the ileum after treatment with prebiotic galacto-oligosaccharides (GOS) [202].”
From Anxiety, depression, and the microbiome: A role for gut peptides (2018) · cites this paper as [202]
Hong et al. found an upregulation of intestinal PYY with the commensal bacteria Bifidobacterium bifidum in rats.
“Hong et al. [202] found an upregulation of intestinal PYY with the commensal bacteria Bifidobacterium bifidum in rats.”
From Anxiety, depression, and the microbiome: A role for gut peptides (2018) · cites this paper as [202]
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Anxiety, depression, and the microbiome: A role for gut peptides
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- Authors
- Department of Public Health Sciences, G. S., Hong, K. B., Kim, J. H., Neo Cremar Co. Ltd., S. 4.-8., Kwon, H. K., Neo Cremar Co. Ltd., S. 4.-8., Han, S. H., Institute for Biomaterials, K. U., Park, Y., Institute for Biomaterials, K. U., Suh, H. J., & Institute for Biomaterials, K. U.
- Affiliations
- Korea University (KR)
- Dongguk University (KR)
- Corresponding author
- Park, Yooheon
- Venue
- Food Technology and Biotechnology
- Published
- 2016
- Volume
- 54
- Issue
- 2
- Pages
- 156-163
- ISSN
- 1330-9862 (ISSN-L)
- 1334-2606
- PMC
- PMC5105622
- OpenAlex
- W2469343084
- Cited by
- 45
- References
- 33
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 7 · 2023: 7 · 2022: 8 · 2021: 3 · 2020: 6 · 2019: 4 · 2017: 4 · 2016: 1
- FWCI
- 3.14
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Food Technology and Biotechnology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- University of Zagreb University Computing Centre (SRCE) (submittedVersion, other-oa)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Keywords
- galactooligosaccharides, prebiotics, Bifidobacterium, glucagon-like peptide-1, peptide YY, gene expression, gut microbiota, functional foods, oral administration
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