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Genome-wide association study of hippocampal atrophy rate in non-demented elders
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In TOMM40-APOC1, SNPs including rs4420638, rs56131196, and rs157582 have been identified as significant loci associated with hippocampal volume atrophy and accelerated cognitive decline in patients with MCI.
“In the TOMM40-APOC1, single-nucleotide polymorphisms (SNPs), including rs4420638, rs56131196, and rs157582, have been identified as significant loci associated with hippocampal volume (HV) atrophy and accelerated cognitive decline in patients with mild cognitive impairment (MCI) [24].”
From Association of APOC1 with cortical atrophy during conversion to Alzheimer’s disease (2025) · cites this paper as [24]
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Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD
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“com 10469 AGING stable; it was greater in MCI subjects who converted to AD than in those who remained stable; and it was greater in fast AD progressors than slow ones [11, 12].”
BackgroundApolipoprotein E in Alzheimer's Disease: An Update
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Self-citationPotkin, S. G., Guffanti, G., Lakatos, A., Turner, J. A., Kruggel, F., Fallon, J. H., Saykin, A. J., Orro, A., Lupoli, S., Salvi, E., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006501 · Cited by 376
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Apolipoprotein CI Knock-Out Mice Display Impaired Memory Functions
Berbée, J. F. P., Vanmierlo, T., Abildayeva, K., Blokland, A., Jansen, P. J., Lütjohann, D., Gautier, T., Sijbrands, E., Prickaerts, J., Hadfoune, M., et al. (2011) · Journal of Alzheimer's Disease · doi:10.3233/jad-2010-100576 · Cited by 25
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Cited by
Sorted by citations
Bae, J., Logan, P. E., Acri, D. J., Bharthur, A., Nho, K., Saykin, A. J., Risacher, S. L., Nudelman, K., Polsinelli, A. J., Pentchev, V., et al. (2023) · Alzheimer's & Dementia · doi:10.1002/alz.13319 · Cited by 14
“36 Many research groups have spotlighted the association between APOC1 and cognitive performance in AD.”
BackgroundAssociation of APOC1 with cortical atrophy during conversion to Alzheimer’s disease
Oh, S., Kim, S., Kim, J. P., Seo, S. W., Park, B.-Y., & Park, H. (2025) · GeroScience · doi:10.1007/s11357-025-01695-6 · Cited by 4
Metadata
- Authors
- Guo, Y., Initiative, O. B. O. A. D. N., Xu, W., Li, J.-Q., Ou, Y.-N., Shen, X.-N., Huang, Y.-Y., Dong, Q., Tan, L., & Yu, J.-T.
- Affiliations
- Department of Neurology, Qingdao Municipal Hospital Affiliated to Qingdao University, Qingdao, China
- Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Venue
- Aging
- Publisher
- Impact Journals, LLC
- Published
- 2019-11-23
- Volume
- 11
- Issue
- 22
- Pages
- 10468-10484
- ISSN
- 1945-4589
- Cited by
- 20
- References
- 5
- Language
- en
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