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The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

Sirtuins in glucose and lipid metabolism

Open access
Ye, Xin, Li, Meiting, Hou, Tianyun, Gao, Tian, Zhu, Wei-guo, Yang, Yang·2017·Oncotarget

Abstract

// Xin Ye 1 , Meiting Li 1 , Tianyun Hou 1 , Tian Gao 1 , Wei-guo Zhu 1 and Yang Yang 1 1 Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China Correspondence to: Yang Yang, email: // Keywords : sirtuins, SIRT1-SIRT7, glucose metabolism, lipid metabolism, regulation Received : April 01, 2016 Accepted : September 13, 2016 Published : September 21, 2016 Abstract Sirtuins are evolutionarily conserved protein, serving as nicotinamide adenine dinucleotide-dependent deacetylases or adenosine diphosphate-ribosyltransferases. The mammalian sirtuins family, including SIRT1~7, is involved in many biological processes such as cell survival, proliferation, senescence, stress response, genome stability and metabolism. Evidence accumulated over the past two decades has indicated that sirtuins not only serve as important energy status sensors but also protect cells against metabolic stresses. In this review, we summarize the background of glucose and lipid metabolism concerning sirtuins and discuss the functions of sirtuins in glucose and lipid metabolism. We also seek to highlight the biological roles of certain sirtuins members in cancer metabolism.

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Crossref · 10.18632/oncotarget.12157

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Metadata

Authors
Ye, X., Li, M., Hou, T., Gao, T., Zhu, W.-G., & Yang, Y.
Venue
Oncotarget
Published
2016-09-21
Volume
8
Issue
1
Pages
1845-1859
ISSN
1949-2553 (ISSN-L)
OpenAlex
W2522309832
Cited by
215
References
17
FWCI
7.73
Type
journal article
Language
en
Open access
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