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Cited by 543

The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.

Mitochondrial dysfunction and oxidative stress in aging and cancer

Open access
Kudryavtseva, Anna V., Krasnov, George S., Dmitriev, Alexey A., Alekseev, Boris Y., Kardymon, Olga L., Sadritdinova, Asiya F., Fedorova, Maria S., Pokrovsky, Anatoly V., Melnikova, Nataliya V., Kaprin, Andrey D., Moskalev, Alexey A., Snezhkina, Anastasiya V.·2016·Oncotarget

Abstract

// Anna V. Kudryavtseva 1,2 , George S. Krasnov 1 , Alexey A. Dmitriev 1 , Boris Y. Alekseev 2 , Olga L. Kardymon 1 , Asiya F. Sadritdinova 1,2 , Maria S. Fedorova 1 , Anatoly V. Pokrovsky 3 , Nataliya V. Melnikova 1 , Andrey D. Kaprin 2 , Alexey A. Moskalev 1,4 and Anastasiya V. Snezhkina 1 1 Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia 2 National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia 3 A.V. Vishnevsky Institute of Surgery, Moscow, Russia 4 Moscow Institute of Physics and Technology, Dolgoprudny, Russia Correspondence to: Anna V. Kudryavtseva, email: // Keywords : oxidative stress, mitochondrial dysfunction, ROS, aging, cancer, Gerotarget Received : November 23, 2015 Accepted : May 28, 2016 Published : June 05, 2016 Abstract Aging and cancer are the most important issues to research. The population in the world is growing older, and the incidence of cancer increases with age. There is no doubt about the linkage between aging and cancer. However, the molecular mechanisms underlying this association are still unknown. Several lines of evidence suggest that the oxidative stress as a cause and/or consequence of the mitochondrial dysfunction is one of the main drivers of these processes. Increasing ROS levels and products of the oxidative stress, which occur in aging and age-related disorders, were also found in cancer. This review focuses on the similarities between ageing-associated and cancer-associated oxidative stress and mitochondrial dysfunction as their common phenotype.

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Metadata

Authors
Kudryavtseva, A. V., Krasnov, G. S., Dmitriev, A. A., Alekseev, B. Y., Kardymon, O. L., Sadritdinova, A. F., Fedorova, M. S., Pokrovsky, A. V., Melnikova, N. V., Kaprin, A. D., Moskalev, A. A., & Snezhkina, A. V.
Venue
Oncotarget
Published
2016-06-05
Volume
7
Issue
29
Pages
44879-44905
ISSN
1949-2553 (ISSN-L)
OpenAlex
W2419530119
Cited by
543
References
48
FWCI
11.44
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Mitochondrial dysfunction and oxidative stress in aging and cancer. https://app.cochat.ai/papers/10.18632/oncotarget.9821
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Kudryavtseva, A. V., Krasnov, G. S., Dmitriev, A. A., Alekseev, B. Y., Kardymon, O. L., Sadritdinova, A. F., Fedorova, M. S., Pokrovsky, A. V., Melnikova, N. V., Kaprin, A. D., Moskalev, A. A., & Snezhkina, A. V. (2016). Mitochondrial dysfunction and oxidative stress in aging and cancer. Oncotarget. https://doi.org/10.18632/oncotarget.9821

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