Oxidative Stress in Human Pathology and Aging: Molecular Mechanisms and Perspectives

The Hallmarks of Aging

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Apoptosis: A Review of Programmed Cell Death

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Nitric Oxide and Peroxynitrite in Health and Disease

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Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

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Oxidative Stress and Antioxidant Defense

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Oxyl radicals, redox-sensitive signalling cascades and antioxidants

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Oxidative Stress: Harms and Benefits for Human Health

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The DNA Damage Response: Making It Safe to Play with Knives

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Activation of apoptosis signalling pathways by reactive oxygen species

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Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints

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Free Radicals, Antioxidants in Disease and Health

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Pathways towards and Away from Alzheimer’s Disease

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Oxidative stress: a concept in redox biology and medicine

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Free Radicals: Properties, Sources, Targets, and Their Implication in Various Diseases

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Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model

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Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling

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Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress

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Antioxidants Maintain Cellular Redox Homeostasis by Elimination of Reactive Oxygen Species

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Cellular mechanisms and physiological consequences of redox-dependent signalling

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Ros and ros-mediated cellular signaling

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Lifestyle, oxidative stress, and antioxidants: Back and forth in the pathophysiology of chronic diseases

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Antioxidants in health and disease

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Mitochondrial dysfunction and oxidative stress in metabolic disorders - A step towards mitochondria based therapeutic strategies

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Hydrogen peroxide sensing and signaling

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Biochemistry of oxidative stress

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DNA Damage Sensing by the ATM and ATR Kinases

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Are oxidative stress-activated signaling pathways mediators of insulin resistance and β-cell dysfunction?

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Oxidative stress and mitochondrial dysfunction in Alzheimer’s disease

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Mitochondrial metabolism of reactive oxygen species

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Specific Aquaporins Facilitate the Diffusion of Hydrogen Peroxide across Membranes

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The sites and topology of mitochondrial superoxide production

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Antioxidants and Prevention of Chronic Disease

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Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

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The role of mitochondria in aging

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JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

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Oxidative Stress in Aging Human Skin

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DNA repair dysregulation from cancer driver to therapeutic target

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Protein Oxidation

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Subcellular Distribution of Superoxide Dismutases (SOD) in Rat Liver

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Beta Cell Dysfunction and Insulin Resistance

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Mechanism of Oxidative Stress in Neurodegeneration

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NADPH oxidases: An overview from structure to innate immunity-associated pathologies

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Pulmonary Oxidative Stress, Inflammation and Cancer: Respirable Particulate Matter, Fibrous Dusts and Ozone as Major Causes of Lung Carcinogenesis through Reactive Oxygen Species Mechanisms

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Oxidative stress in chronic kidney disease

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Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

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Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

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Mitochondria in the aetiology and pathogenesis of Parkinson's disease

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Oxidative stress and Parkinson’s disease

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Oxidative Stress and the Pathogenesis of Alzheimer's Disease

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Hydrogen peroxide sensing, signaling and regulation of transcription factors

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Reactive oxygen species in health and disease

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Amyloid β-peptide (1-42)-induced Oxidative Stress and Neurotoxicity: Implications for Neurodegeneration in Alzheimer's Disease Brain. A Review

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Cisplatin Induces a Mitochondrial-ROS Response That Contributes to Cytotoxicity Depending on Mitochondrial Redox Status and Bioenergetic Functions

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Oxidative stress in end-stage renal disease: an emerging threat to patient outcome

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Chemotherapy-Associated Oxidative Stress: Impact on Chemotherapeutic Effectiveness

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Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease

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Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity

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Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling

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Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity.

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DNA Repair in Mammalian Cells

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Role of Mitochondrial Ca2+ in the Regulation of Cellular Energetics

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The Redox Code

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Apoptosis and Oxidative Stress in Neurodegenerative Diseases

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ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

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Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications

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Bioenergetics and the formation of mitochondrial reactive oxygen species

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Increased ER–mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

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Metabolic Syndrome, Aging and Involvement of Oxidative Stress

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The DNA Damage Response: Implications for Tumor Responses to Radiation and Chemotherapy

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Induction of reactive oxygen species: an emerging approach for cancer therapy

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Hydrogen peroxide – production, fate and role in redox signaling of tumor cells

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Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands

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Superoxide Dismutases: Ancient Enzymes and New Insights

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Oxidative stress induces degradation of mitochondrial DNA

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Mitochondrial dysfunction and oxidative stress in aging and cancer

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Use of hydrogen peroxide as a biocide: new consideration of its mechanisms of biocidal action

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Reactive oxygen species and antioxidant vitamins: Mechanisms of action

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The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4

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Mitochondrial function in normal and diabetic β-cells

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Activation of NADPH Oxidase During Progression of Cardiac Hypertrophy to Failure

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Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

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Mitochondrial Dysfunction in Parkinson’s Disease

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Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice

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Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes

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Oxidative Stress Is Progressively Enhanced With Advancing Stages of CKD

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Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance

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Molecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and β -Cell Dysfunction

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Reactive oxygen species and mitochondrial diseases

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Role of mitochondrial dysfunction in Alzheimer's disease

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The Role of Hydrogen Peroxide in Redox-Dependent Signaling: Homeostatic and Pathological Responses in Mammalian Cells

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Mitochondrial (Dys)function and Insulin Resistance: From Pathophysiological Molecular Mechanisms to the Impact of Diet

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Increased Uncoupling Protein-2 Levels in β-cells Are Associated With Impaired Glucose-Stimulated Insulin Secretion

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Antioxidants in Longevity and Medicine 2014

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Oxidative stress, aging, and diseases

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Introduction

Zeliger, H. I. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91890-9.00031-3