The DOI matches its Crossref record; 18 of the 27 references it cites were found in a registry or an index.
Closing the Gap between Methodologists and End-Users: R as a Computational Back-End
Open accessAbstract
The R environment provides a natural platform for developing new statistical methods due to the mathematical expressiveness of the language, the large number of existing libraries, and the active developer community. One drawback to R, however, is the learning curve; programming is a deterrent to non-technical users, who typically prefer graphical user interfaces (GUIs) to command line environments. Thus, while statisticians develop new methods in R, practitioners are often behind in terms of the statistical techniques they use as they rely on GUI applications. Meta-analysis is an instructive example; cutting-edge meta-analysis methods are often ignored by the overwhelming majority of practitioners, in part because they have no easy way of applying them. This paper proposes a strategy to close the gap between the statistical state-of-the-science and what is applied in practice. We present open-source meta-analysis software that uses R as the underlying statistical engine, and Python for the GUI. We present a framework that allows methodologists to implement new methods in R that are then automatically integrated into the GUI for use by end-users, so long as the programmer conforms to our interface. Such an approach allows an intuitive interface for non-technical users while leveraging the latest advanced statistical methods implemented by methodologists.
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Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552 · cited 1×
“A striking example is the almost universal use of the DerSimonian-Laird method for random effects univariate meta-analysis (DerSimonian and Laird 1986) (the default or only method in the aforementioned programs), irrespective of good data that alternative random effect methods have better statistical…”
MethodMeta-analysis of Observational Studies in Epidemiology<SUBTITLE>A Proposal for Reporting</SUBTITLE>
Stroup, D. F. (2000) · JAMA · doi:10.1001/jama.283.15.2008 · Cited by 20,623
Conducting Meta-Analyses in R with the metafor Package
Viechtbauer, W. (2010) · Journal of Statistical Software · doi:10.18637/jss.v036.i03 · Cited by 20,464 · cited 4×
“Line 2 is the call out to the random effects as implemented by the metafor package (Viechtbauer 2010).”
MethodInfluentialStatistical Methods for Research Workers
Kendall, M. (1937) · Nature · doi:10.1038/139737d0 · Cited by 9,676 · cited 1×
“…disciplines, including the natural sciences, such as physics, astronomy (Airy 1875) and ecology (Osenberg, Sarnelle, and Goldberg 1999), as well as medicine (Simpson and Pearson 1904; Fisher 1925), epidemiology (Stroup et al. 2000), psychology (Glass 1976), and education (Kulik and Kulik 1989).”
BackgroundPrimary, Secondary, and Meta-Analysis of Research
GLASS, G. V. (1976) · Educational Researcher · doi:10.3102/0013189x005010003 · Cited by 4,890 · cited 1×
“…disciplines, including the natural sciences, such as physics, astronomy (Airy 1875) and ecology (Osenberg, Sarnelle, and Goldberg 1999), as well as medicine (Simpson and Pearson 1904; Fisher 1925), epidemiology (Stroup et al. 2000), psychology (Glass 1976), and education (Kulik and Kulik 1989).”
BackgroundBias and Efficiency of Meta-Analytic Variance Estimators in the Random-Effects Model
Viechtbauer, W. (2005) · Journal of Educational and Behavioral Statistics · doi:10.3102/10769986030003261 · Cited by 1,699 · cited 2×
“…random effects univariate meta-analysis (DerSimonian and Laird 1986) (the default or only method in the aforementioned programs), irrespective of good data that alternative random effect methods have better statistical properties (Turner, Omar, Yang, Goldstein, and Thompson 2000; Viechtbauer 2005).”
MethodThe R Commander: A Basic-Statistics Graphical User Interface to R
Fox, J. (2005) · Journal of Statistical Software · doi:10.18637/jss.v014.i09 · Cited by 1,098 · cited 1×
“Our approach is similar in spirit to the R Commander package ( Rcmdr ), which provides an “easy-to-use, cross-platform, extensible GUI” with enough functionality to span a basic statistics course (Fox 2005).”
MethodBax, L., Yu, L.-M., Ikeda, N., Tsuruta, H., & Moons, K. G. (2006) · BMC Medical Research Methodology · doi:10.1186/1471-2288-6-50 · Cited by 514 · cited 2×
“Currently, meta-analysis methods are implemented in many statistical packages, including Stata (Sterne 2009), SPSS (Lipsey and Wilson 2001), SAS (Arthur, Bennett, Huffcutt, Arthur, and Bennett 2001) and R (Schwarzer 2012; Lumley 2009; Viechtbauer 2010), in addition to Microsoft Excel plug-ins, such as MIX (Bax, Yu, Ike…”
MethodGurevitch, J., Curtis, P. S., & Jones, M. H. (2001) · Advances in Ecological Research · doi:10.1016/s0065-2504(01)32013-5 · Cited by 421
Report on Certain Enteric Fever Inoculation Statistics
Simpson, L. (1904) · British medical journal · doi:10.1136/bmj.2.2288.1243 · Cited by 283 · cited 1×
“…disciplines, including the natural sciences, such as physics, astronomy (Airy 1875) and ecology (Osenberg, Sarnelle, and Goldberg 1999), as well as medicine (Simpson and Pearson 1904; Fisher 1925), epidemiology (Stroup et al. 2000), psychology (Glass 1976), and education (Kulik and Kulik 1989).”
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Schonewille, N., Rijkers, N., Berenschot, A., Lijmer, J., van den Heuvel, O. A., & Broekman, B. (2022) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-022-04452-1 · Cited by 42
“A meta-analysis of prevalence of UPs amongst women with psychiatric vulnerability was conducted by use of random effects models with the software programmes OpenMetaAnalyst [30] and Rstudio [31].”
MethodBloodstream Infections in Hospitalized Patients with COVID-19: A Systematic Review and Meta-Analysis
Ippolito, M., Simone, B., Filisina, C., Catalanotto, F. R., Catalisano, G., Marino, C., Misseri, G., Giarratano, A., & Cortegiani, A. (2021) · Microorganisms · doi:10.3390/microorganisms9102016 · Cited by 42
“All the analyses were performed by MI with inputs from AC, using Open Meta-Analyst 8 [9].”
MethodEndovascular therapy for superior vena cava syndrome: A systematic review and meta-analysis
Azizi, A., Shafi, I., Zhao, M. Y., Chatterjee, S., Roth, S., Singh, M., Lakhter, V., & Bashir, R. (2021) · EClinicalMedicine · doi:10.1016/j.eclinm.2021.100970 · Cited by 42
“Data analysis was performed using OpenMeta [Analyst] [15] which uses metafor [16] to calculate weighted estimates.”
MethodDudzik, J. M., Senkus, K. E., Evert, A. B., Raynor, H. A., Rozga, M., Handu, D., & Moloney, L. M. (2023) · The American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2023.08.022 · Cited by 42
Uwimana, A., Gnecco, G., & Riccaboni, M. (2024) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2024.109391 · Cited by 51
Ismaiel, A., Jaaouani, A., Leucuta, D., Popa, S., & Dumitrascu, D. L. (2021) · Biomedicines · doi:10.3390/biomedicines9121890 · Cited by 57
“The data analyses of the systematic review and meta-analysis were performed using R with the Metafor package (OpenMeta [Analyst]) [27,28].”
MethodZhou, Y., & O’Leary, T. J. (2021) · PLoS ONE · doi:10.1371/journal.pone.0254559 · Cited by 48
Memarzia, J., Walker, J., & Meiser‐Stedman, R. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.01.016 · Cited by 46
“…peritraumatic psychological experiences and PTSD symptoms was conducted via user interface software (MAVIS version 1.1.3 (Hamilton, 2017) and OpenMetaAnalyst (Wallace, et al., 2012)) which run the meta-analyses using R (version 3.4.3) and the ‘metafor’ (version 2.0.0) package (Viechtbauer, 2010).”
MethodInfluentialSystematic review of co-occurring OCD and TD: Evidence for a tic-related OCD subtype?
Kloft, L., Steinel, T., & Kathmann, N. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.09.021 · Cited by 48
“NQO1Gene C609T Polymorphism (dbSNP: rs1800566) and Digestive Tract Cancer Risk: A Meta-Analysis.”
Yadav, U., Kumar, P., & Rai, V. (2018) · Nutrition and Cancer · doi:10.1080/01635581.2018.1460674 · Cited by 45
Ospina, N. S., Maraka, S., Ycaza, A. E. E. D., O'Keeffe, D. T., Brito, J. P., Gionfriddo, M. R., Castro, M. R., Morris, J. C., Erwin, P. J., & Montori, V. M. (2015) · Clinical Endocrinology · doi:10.1111/cen.12975 · Cited by 51
Toh, S., Chia, P.-F., & Fong, K. N. K. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.964196 · Cited by 40
“For studies that did not report the mean change score and SD but provided pre and post/follow-up scores, the Open Meta-Analyst software (27) was used to calculate the mean change scores.”
MethodThe Impact of Dental Implant Length on Failure Rates: A Systematic Review and Meta-Analysis
Abdel-Halim, M., Issa, D. R., & Chrcanovic, B. R. (2021) · Materials · doi:10.3390/ma14143972 · Cited by 41
“The data were analyzed using the statistical software OpenMeta [Analyst] [16].”
MethodChildhood Obesity and Overweight in Ghana: A Systematic Review and Meta-Analysis
Akowuah, P. K., & Kobia‐Acquah, E. (2020) · Journal of Nutrition and Metabolism · doi:10.1155/2020/1907416 · Cited by 45
van Loon, I. V., Joosten, H., Iyasere, O., Johansson, L., Hamaker, M., & Brown, E. (2019) · Archives of gerontology and geriatrics (Print) · doi:10.1016/j.archger.2019.05.015 · Cited by 40
Mean platelet volume values in preeclampsia: A systematic review and meta-analysis
Bellos, I., Fitrou, G., Pergialiotis, V., Papantoniou, N. E., & Daskalakis, G. (2018) · Pregnancy Hypertension · doi:10.1016/j.preghy.2018.06.016 · Cited by 45
Clinical Outcomes in Hypertensive Emergency: A Systematic Review and Meta‐Analysis
Siddiqi, T., Usman, M., Rashid, A. M., Javaid, S. S., Ahmed, A., Clark, D., Flack, J., Shimbo, D., Choi, E., Jones, D. W., et al. (2023) · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease · doi:10.1161/jaha.122.029355 · Cited by 39
Safety of COVID-19 vaccines in multiple sclerosis: A systematic review and meta-analysis
Stefanou, M.-I., Palaiodimou, L., Theodorou, A., Christodoulou, M., Tzartos, J. S., Tzanetakos, D., Kitsos, D. K., Chondrogianni, M., Zouvelou, V., Dardiotis, E., et al. (2023) · Multiple Sclerosis · doi:10.1177/13524585221150881 · Cited by 39
Ismaiel, A., Ciobanu, O. S., Ismaiel, M., Leucuta, D., Popa, S., David, L., Ensar, D., Srouji, N. A., & Dumitrascu, D. L. (2022) · Biomedicines · doi:10.3390/biomedicines10092101 · Cited by 39
“The data collection for the systematic review and the meta-analysis were analyzed in R with the Metafor package in OpenMeta[Analyst] [34,35].”
MethodImpact of standardized clinical pathways on esophagectomy: a systematic review and meta-analysis.
Puccetti, F., Wijnhoven, B., Kuppusamy, M., Hubka, M., & Low, D. (2021) · Diseases of the esophagus · doi:10.1093/dote/doab027 · Cited by 39
Jabbar‐Lopez, Z. K., Ung, C. Y., Alexander, H., Gurung, N., Chalmers, J. R., Danby, S. G., Cork, M. J., Peacock, J. L., & Flohr, C. (2020) · Clinical & Experimental Allergy · doi:10.1111/cea.13797 · Cited by 46
Morphine in acute coronary syndrome: systematic review and meta-analysis
Duarte, G., Nunes-Ferreira, A., Rodrigues, F., Pinto, F., Ferreira, J., Costa, J., & Caldeira, D. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-025232 · Cited by 39
Non-A non-B aortic dissection: a systematic review and meta-analysis
Carino, D., Singh, M., Molardi, A., Agostinelli, A., Goldoni, M., Pacini, D., & Nicolini, F. (2018) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezy337 · Cited by 39
“A systematic search was performed using the MEDLINE database (National Library of Medicine, Bethesda, MD, USA) to identify all published studies reporting data from January 2000 to December 2017.”
MethodInfluentialTorabinejad, M., Nosrat, A., Verma, P., & Oyoyo, U. (2017) · Journal of Endodontics · doi:10.1016/j.joen.2017.06.029 · Cited by 246
Survival and complications of implants to support craniofacial prosthesis: A systematic review.
Chrcanovic, B., Nilsson, J., & Thor, A. (2016) · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery · doi:10.1016/j.jcms.2016.07.030 · Cited by 39
“The datawere analyzed using the softwares OpenMeta[Analyst] (Wallace et al., 2012) and Review Manager (version 5.3.3, The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen, Denmark, 2014). lications of implants to support craniofacial prosthesis: A systematic /10.1016/j.jcms.2016.07.030”
MethodInfluentialPostrelease mortality in istiophorid billfish
Musyl, M. K., Moyes, C. D., Brill, R. W., Mourato, B. L., West, A., McNaughton, L. M., Chiang, W., & Sun, C. (2014) · Canadian Journal of Fisheries and Aquatic Sciences · doi:10.1139/cjfas-2014-0323 · Cited by 34
“2009) and Open Meta-Analyst (Wallace et al. 2012).”
MethodInfluentialWatanabe, A., So, M., Mitaka, H., Ishisaka, Y., Takagi, H., Inokuchi, R., Iwagami, M., & Kuno, T. (2022) · Mycopathologia · doi:10.1007/s11046-022-00627-8 · Cited by 44
Netterström-Wedin, F., Matthews, M., & Bleakley, C. (2021) · Sports Health A Multidisciplinary Approach · doi:10.1177/19417381211029953 · Cited by 57
Sensitivity of ID NOW and RT–PCR for detection of SARS-CoV-2 in an ambulatory population
Tu, Y.-P., Iqbal, J., O, & Leary, T. (2021) · eLife · doi:10.7554/elife.65726 · Cited by 38
“Three papers in which with a low risk of bias were deemed appropriate to include in a meta-analysis were analyzed using a diagnostic effects model (DerSimonian and Laird, 1986) as implemented by OpenMetaAnalyst software program (Wallace et al., 2012).”
MethodMoorthy, D., Merrill, R. D., Namaste, S. M. L., & Iannotti, L. L. (2020) · Advances in Nutrition · doi:10.1093/advances/nmaa070 · Cited by 47
“The pooled analysis was conducted using random-effects modeling in OpenMeta[Analyst] software (11).”
MethodMultisystem inflammatory syndrome in pediatric COVID-19 patients: a meta-analysis
Toraih, E. A., Hussein, M. H., Elshazli, R. M., Kline, A., Munshi, R., Sultana, N., Taghavi, S., Killackey, M. T., Duchesne, J. C., Fawzy, M. S., et al. (2021) · World Journal of Pediatrics · doi:10.1007/s12519-021-00419-y · Cited by 56
The prevalence of intrusive memories in adult depression: A meta-analysis
Payne, A., Kralj, A., Young, J., & Meiser‐Stedman, R. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.04.055 · Cited by 41
“All analyses were performed in OpenMeta[Analyst] (Wallace et al., 2012).”
Sneiders, D., Bulstra, L., Hundepool, C., Treling, W. J., Hovius, S., & Shin, A. (2019) · Plastic and Reconstructive Surgery · doi:10.1097/prs.0000000000005720 · Cited by 38
Ghia, C. J., Dhar, R., Koul, P. A., Rambhad, G. S., & Fletcher, M. A. (2019) · Clinical Medicine Insights Circulatory Respiratory and Pulmonary Medicine · doi:10.1177/1179548419862790 · Cited by 46
Auditory N100 gating in patients with schizophrenia: A systematic meta-analysis.
Rosburg, T. (2018) · Clinical Neurophysiology · doi:10.1016/j.clinph.2018.07.012 · Cited by 38
Yes–no Answers versus Check-all in Self-Administered Modes: A Systematic Review and Analyses
Callegaro, M., Murakami, M., Tepman, Z., & Henderson, V. R. (2015) · International Journal of Market Research · doi:10.2501/ijmr-2015-014a · Cited by 38
“6 We performed a meta-analysis using OpenMeta (Wallace et al. 2012).”
MethodDobrijević, Z., Gligorijević, N., Šunderić, M., Penezić, A., Miljuš, G., Tomić, S., & Nedić, O. (2022) · Reviews in Medical Virology · doi:10.1002/rmv.2378 · Cited by 40
Ismaiel, A., Bucșa, C., Farcas, A. M., Leucuta, D., Popa, S., & Dumitrascu, D. L. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.749969 · Cited by 38
Wilcoxon, L., Meiser-Stedman, R., & Burgess, A. (2021) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-021-00367-z · Cited by 37
van Kempen, E. J., Post, M., Mannil, M., Kusters, B., ter Laan, M., Meijer, F., & Henssen, D. (2021) · Cancers · doi:10.3390/cancers13112606 · Cited by 37
“) and OpenMeta[Analyst] software (MetaAnalyst, Brown University EPBC [24]), which is the visual front-end for the R package (version 12.”
InfluentialIppolito, M., Catalisano, G., Marino, C., Fucà, R., Giarratano, A., Baldi, E., Einav, S., & Cortegiani, A. (2021) · Resuscitation · doi:10.1016/j.resuscitation.2021.04.025 · Cited by 37
Alemayehu, T., & Hailemariam, M. (2020) · Scientific Reports · doi:10.1038/s41598-020-77696-6 · Cited by 37
Ro, K., Heo, J., & Lee, D.-H. (2018) · Clinical Orthopaedics and Related Research · doi:10.1007/s11999.0000000000000205 · Cited by 37
Rogliani, P., Matera, M. G., Ora, J., Cazzola, M., & Calzetta, L. (2017) · International Journal of COPD · doi:10.2147/copd.s146338 · Cited by 41
“org) to assess the quality of evidence.(21,32,35) The statistical significance was assessed for P,0.”
Alsawas, M., Zaiem, F., Larrea-Mantilla, L., Almasri, J., Erwin, P., Upchurch, G., & Murad, M. (2017) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2017.05.082 · Cited by 37
Sneiders, D., Houwen, T., Pengel, L., Polak, W., Dor, F., & Hartog, H. (2018) · Transplantation · doi:10.1097/tp.0000000000001936 · Cited by 37
“5 correction factor was used, if the number of events was 0.(29) For each outcome, the results were presented in forest plots with an odds ratio (OR) and 95% confidence interval (CI).”
MethodA meta-analysis on resting state high-frequency heart rate variability in bulimia nervosa.
Peschel, S. K. V., Feeling, N. R., Vögele, C., Kaess, M., Thayer, J. F., & Koenig, J. (2016) · European Eating Disorders Review · doi:10.1002/erv.2454 · Cited by 36
Bello, K., Jusoh, T. N. A. M., Irekeola, A., Abu, N., Amin, N. A. M. M., Mustaffa, N., & Shueb, R. H. (2023) · Healthcare · doi:10.3390/healthcare11071011 · Cited by 36
Gómez-Soria, I., Marín-Puyalto, J., Peralta-Marrupe, P., Latorre, E., & Calatayud, E. (2022) · Archives of gerontology and geriatrics (Print) · doi:10.1016/j.archger.2022.104751 · Cited by 36
Nitschke, E., Gottesman, K., Hamlett, P., Mattar, L., Robinson, J., Tovar, A. P., & Rozga, M. (2022) · Nutrients · doi:10.3390/nu14091729 · Cited by 47
“Meta-analyses were conducted and forest plots were created using OpenMetaAnalyst [30] and RStudio [31] software.”
MethodTreatment for chronic hepatitis E virus infection: A systematic review and meta‐analysis
Gorris, M., van der Lecq, B., van Erpecum, K. V., & de Bruijne, J. (2020) · Journal of Viral Hepatitis · doi:10.1111/jvh.13456 · Cited by 36
“Treatment was initiated after a median infection duration of 50 (12-120) months.”
BackgroundKim, J.-H., Heo, J., & Lee, D.-H. (2020) · Orthopaedic Journal of Sports Medicine · doi:10.1177/2325967120959280 · Cited by 36
D'Souza, R., Wuebbolt, D., Andrejevic, K., Ashraf, R., Nguyen, V., Zaffar, N., Rotstein, D., & Wyne, A. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.544434 · Cited by 36
Perini, P., Massoni, C. B., Mariani, E., Ucci, A., Fanelli, M., Azzarone, M., & Freyrie, A. (2019) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2019.03.032 · Cited by 36
Soud, M., Alahdab, F., Ho, G., Kuku, K. O., Cejudo-Tejeda, M., Hideo-Kajita, A., Gonçalves, P. D. A., Teles, R., Waksman, R., & García-García, H. (2019) · The International Journal of Cardiovascular Imaging · doi:10.1007/s10554-019-01582-0 · Cited by 35
Pharmacological treatments in asthma‐affected horses: A pair‐wise and network meta‐analysis
Calzetta, L., Roncada, P., Cave, D. D., Bonizzi, L., Urbani, A., Pistocchini, E., Rogliani, P., & Matera, M. G. (2017) · Equine Veterinary Journal · doi:10.1111/evj.12680 · Cited by 33
“OpenMetaAnalyst [27] was used to perform pair-wise meta-analysis, GeMTC [28] for network meta-analysis and GraphPad Prism to graph the data.”
MethodHuygens, S., Mokhles, M. M., Hanif, M., Bekkers, J., Bogers, A., Mölken, M. R.-V., & Takkenberg, J. (2016) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezw101 · Cited by 35
“The meta-analysis, heterogeneity tests, subgroup analysis and funnel plots were performed in Microsoft Office Excel 2010, Shapiro–Wilk tests using SPSS and leave-one-out sensitivity and univariable meta-regression analyses using open-source meta-analysis software that uses R as the underlying statistical engine [13].”
MethodLiu, Y.-H., Jhou, H.-J., Chou, M.-H., Wu, S.-T., Cha, T., Yu, D.-S., Sun, G.-H., Chen, P.-H., & Meng, E. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12040532 · Cited by 34
“(Appendix I) [13] All statistical analyses were performed using the “metaphor” and “meta” [14,15] packages of R software version 4.”
MethodThe effect of race in head and neck cancer: A meta-analysis controlling for socioeconomic status
Russo, D. P., Tham, T., Bardash, Y., & Kraus, D. H. (2020) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2020.102624 · Cited by 37
Chandrasekar, V., Desai, M., Aziz, M., Patel, H., Gorrepati, V., Jegadeesan, R., Rai, T., Sathyamurthy, A., Murino, A., Hassan, C., et al. (2019) · Endoscopy · doi:10.1055/a-0994-4361 · Cited by 34
“All metaanalytic computations, including the estimates and 95%CIs for pooled rates as well as the measurement of heterogeneity (measured as I2 statistics) were performed using statistical software Open Meta analyst [10].”
MethodVictorson, D. E., Sauer, C. M., Wolters, L., Maletich, C., Lukoff, K., & Sufrin, N. (2020) · Mindfulness · doi:10.1007/s12671-020-01373-y · Cited by 33
Gopinatth, V., Mameri, E. S., Casanova, F. J., Khan, Z. A., Jackson, G. R., McCormick, J. R., Brophy, R. H., Knapik, D. M., LaPrade, R. F., & Chahla, J. A. (2023) · Orthopaedic Journal of Sports Medicine · doi:10.1177/23259671231188383 · Cited by 30
João, V., Castelo, F., Barros, B. S., Ribau, A., Carvalho, A., & de Sousa, R. J. G. (2023) · The Journal of Arthroplasty · doi:10.1016/j.arth.2023.06.017 · Cited by 38
Berezin, L., Nagappa, M., Poorzargar, K., Saripella, A., Ariaratnam, J., Butris, N., Englesakis, M. F., & Chung, F. F. (2022) · Journal of Clinical Anesthesia · doi:10.1016/j.jclinane.2022.110993 · Cited by 41
Efficacy of respiratory tele-rehabilitation in COPD patients: Systematic review and meta-analysis.
Ora, J., Prendi, E., Attinà, M. L., Cazzola, M., Calzetta, L., & Rogliani, P. (2022) · Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace · doi:10.4081/monaldi.2022.2105 · Cited by 33
“OpenMetaAnalyst software [12] was used to perform meta-analysis in pairs and to make data graphs.”
MethodChanges in Stroke Hospital Care During the COVID-19 Pandemic
Katsanos, A., Palaiodimou, L., Zand, R., Yaghi, S., Kamel, H., Navi, B., Turc, G., Benetou, V., Sharma, V. K., Mavridis, D., et al. (2021) · Stroke · doi:10.1161/strokeaha.121.034601 · Cited by 33
Augusto, S., Ratola, N., Tarín‐Carrasco, P., Jiménez‐Guerrero, P., Turco, M., Schuhmacher, M., Costa, S., Teixeira, J. P., & Costa, C. (2020) · Environment International · doi:10.1016/j.envint.2020.106056 · Cited by 54
Alkhatib, N., Younis, M., Hegazy, A., & Ibrahim, T. (2018) · International Orthopaedics · doi:10.1007/s00264-018-3998-4 · Cited by 33
Richard, A., Scheffer, I. E., & Wilson, S. J. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.12.036 · Cited by 37
Patel, D., Tsang, J., Saripella, A., Nagappa, M., Islam, S., Englesakis, M. F., & Chung, F. F. (2021) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.9820 · Cited by 33
“8,9 The combined test characteristics were recalculated for each type of study population (sleep clinic patients, medical population with comorbidities, surgical patients, commercial drivers, and general population) at each AHI or RDI cut-off (AHI or RDI ≥ 5, ≥ 15, and ≥ 30 events/h) and forest…”
Yuwanati, M., Gondivkar, S., Sarode, S., Gadbail, A., Sarode, G., Patil, S., & Mhaske, S. (2021) · Clinics and Practice · doi:10.3390/clinpract11020040 · Cited by 32
“4 (Academic Use), The Cochrane Collaboration, 2020 and OpenMeta [Analyst] [9].”
Badesha, A. S., Bains, P. R. S., Bains, B. R. S., & Khan, T. (2021) · Journal of Vascular Surgery: Venous and Lymphatic Disorders · doi:10.1016/j.jvsv.2021.04.014 · Cited by 32
Wada, Y., Irekeola, A., Engku Nur Syafirah, E. A. R., Yusof, W., Lee, L., Muhammad, S. L., Harun, A., Chan, Y.-A.-Y.-A., & Zaidah, A. (2021) · Antibiotics · doi:10.3390/antibiotics10020138 · Cited by 32
Farias, I. P. S. E., de Sousa, S. D., de Almeida, L. D. F. D., Santiago, B., Pereira, A., & Cavalcanti, Y. (2020) · Ciência & Saúde Coletiva · doi:10.1590/1413-81232020256.18252018 · Cited by 32
Breath biomarkers in idiopathic pulmonary fibrosis: a systematic review
Hayton, C., Terrington, D. L., Wilson, A. M., Chaudhuri, N., Leonard, C. T., & Fowler, S. J. (2019) · Respiratory Research · doi:10.1186/s12931-019-0971-8 · Cited by 36
“Statistical analysis was performed using OpenMeta-Analyst software [52].”
MethodKobia‐Acquah, E., Flitcroft, I., Akowuah, P. K., Lingham, G., & Loughman, J. (2022) · Ophthalmic and Physiological Optics · doi:10.1111/opo.13035 · Cited by 32
“edu/openm eta/), an open source software for meta- analysis.(33) Individual study proportions and pooled estimates were assessed and reported with a 95% confidence interval.”
Fernando, S. M., Tran, A., Cheng, W., Rochwerg, B. N., Strauss, S. A., Mutter, E., McIsaac, D. I., Kyeremanteng, K., Kubelik, D., Jetty, P., et al. (2022) · Academic Emergency Medicine · doi:10.1111/acem.14475 · Cited by 43
Allopurinol to reduce cardiovascular morbidity and mortality: A systematic review and meta-analysis
van der Pol, K. H., Wever, K., Verbakel, M., Visseren, F., Cornel, J., & Rongen, G. (2021) · PLoS ONE · doi:10.1371/journal.pone.0260844 · Cited by 31
“The meta-analysis was performed using the OpenMeta[analyst] software package [14].”
MethodClinical characteristics of 4499 COVID‐19 patients in Africa: A meta‐analysis
Olumade, T. J., & Uzairue, L. I. (2021) · Journal of Medical Virology · doi:10.1002/jmv.26848 · Cited by 37
Fusca, L., Perelman, I., Fergusson, D., Boutet, M., & Chen, I. (2019) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2018.04.007 · Cited by 31
Ligature-Induced Experimental Peri-Implantitis—A Systematic Review
Reinedahl, D., Chrcanovic, B., Albrektsson, T., Tengvall, P., & Wennerberg, A. (2018) · Journal of Clinical Medicine · doi:10.3390/jcm7120492 · Cited by 31
Plante, D., Cook, J. D., & Goldstein, M. (2017) · Journal of Sleep Research · doi:10.1111/jsr.12498 · Cited by 31
“Metaanalysis was performed using the random-effects model (DeSimonian-Laird), utilizing OpenMetaAnalyst, an opensource, cross-platform software (http://www.cebm.brown.ed u/open_meta/; Wallace et al., 2012).”
MethodGanesh, S., Ashok, A., Kumar, C., & Thirthalli, J. (2016) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2016.05.006 · Cited by 31
Yadav, U., Kumar, P., & Rai, V. (2016) · Egyptian Journal of Medical Human Genetics · doi:10.1016/j.ejmhg.2015.06.005 · Cited by 31
Meta-analysis of Statin Use for the Acute Therapy of Spontaneous Intracerebral Hemorrhage.
Pérez, J., Yıldız, Ö., Schneider, T., & Nimsky, C. (2015) · Journal of Stroke & Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2015.06.036 · Cited by 31
“All calculationswere carried out with the free statistical software OpenMetaAnalyst (Center for Evidence-based Medicine (CEBM), Providence, RI, USA).(13)”
Method17. Phylogenetic Nonindependence and Meta-analysis
Lajeunesse, M. J., Rosenberg, M. S., & Jennions, M. D. (2013) · Princeton University Press eBooks · doi:10.1515/9781400846184-019 · Cited by 58
ABO and Rh blood groups and risk of infection: systematic review and meta-analysis
Butler, E. A., Parikh, R., Grandi, S. M., Ray, J. G., & Cohen, E. (2023) · BMC Infectious Diseases · doi:10.1186/s12879-023-08792-x · Cited by 33
“All analyses were conducted using Open MetaAnalyst [11].”
MethodBáez, S., Tangarife, M. A., Davila-Mejia, G., Trujillo‐Güiza, M. L., & Forero, D. A. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1192683 · Cited by 35
Acute Arterial Ischemic Stroke Following COVID-19 Vaccination
Stefanou, M., Palaiodimou, L., de Sousa, D. A., Theodorou, A., Bakola, E., Katsaros, D. E., Halvatsiotis, P., Tzavellas, E., Naska, A., Coutinho, J. M., et al. (2022) · Neurology · doi:10.1212/wnl.0000000000200996 · Cited by 36
“0 (package: metafor).(24,25) Data Availability All data generated or analyzed during this study are included in this article and its supplementary information files.”
BackgroundKoutalos, A., Varitimidis, S., Malizos, K., & Karachalios, T. (2021) · HIP International · doi:10.1177/11207000211004383 · Cited by 30
Hong, B.-L., D'Cunha, R. R., Li, P., Alshaer, M., Alghamdi, W. A., An, G.-H., & Peloquin, C. (2020) · Clinical Therapeutics · doi:10.1016/j.clinthera.2020.09.009 · Cited by 30
Pregnancy outcomes in women with cardiothoracic transplants: A Systematic review and meta-analysis.
Acuna, S., Zaffar, N., Dong, S., Ross, H., & D'Souza, R. (2019) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2019.11.018 · Cited by 30
MTHFR C677T polymorphism and risk of esophageal cancer: An updated meta-analysis
Kumar, P., & Rai, V. (2018) · Egyptian Journal of Medical Human Genetics · doi:10.1016/j.ejmhg.2018.04.003 · Cited by 30
“All statistical analyses were undertaken by MetaAnalyst [36] and MIX version 1.7 [37].”
MethodInfluentialMiligkos, M., Papamichael, K., Casteele, N. V., Mantzaris, G., Gils, A., Levesque, B., & Zintzaras, E. (2016) · Clinical Therapeutics · doi:10.1016/j.clinthera.2016.03.018 · Cited by 30
“PL IS (17), CS (56) 18 36 50 9 No ND Schreiber et al,(35) 2007 (PRECISE-II) CER 400 mg every 4 wk 20 IS (27), CS (22), IS+CS (13) 216 38 43 9 24 ND Response, remission PL IS (25), CS (21), IS+CS (16) 212 38 52 7 24 ND”
InfluentialHittner, J. (2016) · Psychology of Addictive Behaviors · doi:10.1037/adb0000162 · Cited by 30
“All analyses were conducted using OpenMetaAnalyst (Wallace et al., 2012) which incorporates the R package metafor (Viechtbauer, 2010), IBM/SPSS version 22, and SAS Enterprise Guide version 5.1 (SAS Institute, 2013).”
MethodInfluentialPrevalence of self-medication in Ghana: a systematic review and meta-analysis
Opoku, R., Dwumfour-Asare, B., Agrey-Bluwey, L., Appiah, N. E., Ackah, M., Acquah, F., Asenso, P. F., & Issaka, A.-A. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-064627 · Cited by 30
Guest, N. S., Raj, S., Landry, M. J., Mangels, A. R., Pawlak, R., Senkus, K. E., Handu, D., & Rozga, M. (2024) · Advances in Nutrition · doi:10.1016/j.advnut.2024.100294 · Cited by 40
Hodge, I., Quille, P., & O’Connell, S. (2024) · Animals · doi:10.3390/ani14040568 · Cited by 40
“Open meta-analysis software (version 5.26.14) was used in this meta-analysis-style review to identify compounds with significant CH 4 -mitigating efficacy while being safe for use in beef and dairy cattle [104].”
MethodInfluentialBuonanno, P., Marra, A., Iacovazzo, C., Vargas, M., Coviello, A., Squillacioti, F., Nappi, S., de Siena, A. U., & Servillo, G. (2023) · British Journal of Anaesthesia · doi:10.1016/j.bja.2023.09.011 · Cited by 32
Tanwani, R., Danquah, M. O., Butris, N., Saripella, A., Yan, E., Kapoor, P., Englesakis, M. F., Tang‐Wai, D. F., Tartaglia, M. C., He, D., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0291291 · Cited by 34
“Meta-regression was performed using Open Meta Analyst for the variables age, sample size, and female gender when the number of studies was five or greater [16].”
Metadata
- Authors
- Wallace, B. C., Dahabreh, I. J., Trikalinos, T. A., Lau, J., Trow, P., & Schmid, C. H.
- Affiliations
- Tufts University (US)
- Venue
- Journal of Statistical Software
- Publisher
- Foundation for Open Access Statistic
- Published
- 2012
- Volume
- 49
- Issue
- 5
- ISSN
- 1548-7660 (ISSN-L)
- OpenAlex
- W2120771911
- Cited by
- 1,125
- References
- 27
- Citations by year
- 2026: 50 · 2025: 89 · 2024: 115 · 2023: 105 · 2022: 127 · 2021: 143 · 2020: 133 · 2019: 94 · 2018: 76 · 2017: 68 · 2016: 65 · 2015: 37 · 2014: 17 · 2013: 4 · 2012: 1
- FWCI
- 18.44
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by
- Locations
- Journal of Statistical Software (publishedVersion, cc-by)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Data Analysis with R
- Social Sciences › Decision Sciences › Information Systems and Management › Scientific Computing and Data Management
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Keywords
- R, meta-analysis software, graphical user interface, Python, open source software, software integration, statistical software development, non-technical users
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