MCQG-SRefine: Multiple Choice Question Generation and Evaluation with Iterative Self-Critique, Correction, and Comparison Feedback
Open accessAbstract
Automatic question generation (QG) is essential for AI and NLP, particularly in intelligent tutoring, dialogue systems, and fact verification. Generating multiple-choice questions (MCQG) for professional exams, like the United States Medical Licensing Examination (USMLE), is particularly challenging, requiring domain expertise and complex multi-hop reasoning for high-quality questions. However, current large language models (LLMs) like GPT-4 struggle with professional MCQG due to outdated knowledge, hallucination issues, and prompt sensitivity, resulting in unsatisfactory quality and difficulty. To address these challenges, we propose MCQG-SRefine, an LLM self-refine-based (Critique and Correction) framework for converting medical cases into high-quality USMLE-style questions. By integrating expert-driven prompt engineering with iterative self-critique and self-correction feedback, MCQG-SRefine significantly enhances human expert satisfaction regarding both the quality and difficulty of the questions. Furthermore, we introduce an LLM-as-Judge-based automatic metric to replace the complex and costly expert evaluation process, ensuring reliable and expert-aligned assessments.
AI snapshot
Written from the paper’s full text.
TL;DR
MCQG-SRefine is an LLM self-refine framework that converts medical cases into USMLE-style multiple-choice questions using iterative critique, correction, and comparison feedback. It improves expert-rated question quality and difficulty over GPT-4 and introduces an LLM-as-Judge metric that better aligns with expert evaluation after filtering criteria.
Key findings
- Human experts preferred MCQG-SRefine questions over GPT-4 questions with a 72.5% win rate, 10% tie, and 17.5% loss; LLM-as-Judge preference was 79.97% in favor and 20.03% against.
- With expert-provided topics and test points, MCQG-SRefine reduced easy questions by about 80%, increased medium questions 2.25-fold, and increased hard questions 4-fold; with machine-provided topics and test points, easy questions decreased 33.3%, medium increased 2-fold, and hard questions did not increase.
- Filtering the LLM-as-Judge criteria from 30 to 10 key criteria improved correlation with expert evaluation, raising Cohen’s kappa from 0.226 (slight reliability) to 0.539 (moderate reliability).
- Qualitative analysis found 7.5% of GPT-4 questions contained factual errors versus 5% for MCQG-SRefine; GPT-4 often included the answer or obvious keywords, while MCQG-SRefine was more concise but rarely omitted too much information, making inference harder in 7.5% of cases.
Methods
- The pipeline takes a medical case plus topics and test points, retrieves few-shot USMLE examples from MedQA with ColBERT, and generates context, question, correct answer, and distractors. It then collects QA feedback, critiques each component using a scoring guide, and iteratively corrects until feedback scores exceed a fixed threshold.
- Topics were selected from 41 NBME guideline topics; test points were retrieved from the USMLE content outline using ColBERT and refined by the LLM or human experts. Medical cases came from PMC-Patients patient summaries averaging about 419 words.
- Experiments used gpt-4-0125-preview with temperature and top-p set to 1, generating 373 questions from human-annotated inputs and 385 from LLM-generated inputs. Human evaluation used two medical experts plus a third expert for final decisions; difficulty was classified as Easy, Medium, or Difficult with AMBOSS examples. LLM-as-Judge used rating and comparison modes over filtered criteria.
Limitations
- The paper states that generalizability to other domains, languages, or question types remains unexplored.
- The paper states that LLM-as-Judge carries self-evaluation bias because GPT-4 is used for both generation and evaluation; GPT-4 still showed inconsistencies in about 35% of cases due to option order, and evaluation is cognitively different from generation.
- The paper states a risk of over-self-critique, where later refinements do not always outperform earlier ones; round-wise analysis found 30% of best scores came from the first round for human-generated topics and 24.9% for machine-generated topics. Evident from the text, the human preference evaluation relied on two medical experts plus a third adjudicator, and the paper does not report the exact number of human-evaluated question pairs.
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Cites
Statistics
Claims the paper makes
16 of 39 cited sources checked · 6 supported · 0 flagged · accuracy not yet measured
- Interpretationcitation
GPT-4's conservative behavior is interpreted as a shortcut learned during RLHF to reduce output diversity and mitigate hallucinations.
“We interpret this as a shortcut behavior learned by GPT-4 during aligning with human preferences stage training (e.g., RLHF (Ouyang et al., 2022)) to reduce output diversity to mitigate hallucinations (Kirk et al., 2023).”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites Ouyang et al., 2022
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Kirk et al., 2023 source
Section 6 (Experimental Results; page unavailable) reports that RLHF reduces output diversity in the models studied. But Section 5.1 uses GPT-4 as an evaluator, not as a model whose conservative behavior is examined. The cited paper does not attribute reduced diversity to a shortcut learned by GPT-4 or say that it mitigates hallucinations. (LLM, conf=0.88)
Experimental — accuracy not yet measured
- Premisecitation
LLM-as-Judge correlates more closely with human evaluations than traditional metrics.
“Recent research indicates that LLM-as-Judge correlates more closely with human evaluations than traditional metrics (Chen et al., 2023a; Chiang and Lee, 2023; Kocmi and Federmann, 2023; Zheng et al., 2024; Zhang et al., 2024a; Kim et al., 2023, 2024), though these methods remain underexplored in medical NLP tasks.”
Quote in the paperSubstantial claim1 of 3 sources checked- cites Chen et al., 2023a
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Chiang and Lee, 2023 source
- cites Kocmi and Federmann, 2023 source
The Results (§4.1) report that the GPT-4 translation-quality metric outperformed other reference-based metrics against human evaluations at the system level. But §4.4 says GPT-4 was slightly behind the top-performing metrics in segment-level correlation with human judgments. The claim therefore overgeneralizes a finding about translation evaluation at the system level. (LLM, conf=0.88)
Experimental — accuracy not yet measured
- Findingcitation
Variation across critique dimensions, such as individual scoring versus pairwise comparison, adds to the difficulties of using LLMs for evaluation.
“Third, inconsistencies across different critique dimensions (e.g., individual scoring vs. pairwise comparison) further compound these challenges, which is aligned with recent work findings (Lan et al., 2024).”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Lan et al., 2024 source
- Premisecitation
The quality and difficulty of GPT-4 generated USMLE questions often fall below expectations.
“Lastly, the quality and difficulty of the questions often do not meet expectations (Artsi et al., 2024; Benítez et al., 2024) (Limit3).”
Quote in the paperSubstantial claim2 of 2 sources checked- cites Artsi et al., 2024 source
The Results (Descriptive summary of results; page unavailable) report faulty questions across the reviewed studies, including GPT-4 anatomy questions with low difficulty or invalidity. But the USMLE Step 1 questions were not independently evaluated, and the assessed GPT-4 internal-medicine questions were mostly deemed valid. The review therefore supports concerns about question quality and difficulty, but not the claim specifically about GPT-4-generated USMLE questions often falling short. (LLM, conf=0.85)
Experimental — accuracy not yet measured - cites Benítez et al., 2024 source
The Board exam preparation section says ChatGPT-generated USMLE-style questions were generally lower in complexity and not advanced enough to serve as a stand-alone question bank. That supports the concern about question difficulty and adequacy, but the paper does not identify the question-generating model as GPT-4. (LLM, conf=0.86)
Experimental — accuracy not yet measured
- Findingown data
Filtering the 30 expert-designed criteria down to a combination of 10 key criteria improved the correlation between LLM-as-Judge and expert evaluations, raising Cohen's kappa from 0.226 to 0.539.
“By further exploring the filtering methods for the 30 criteria, we finally screened out a combination of 10 key criteria. This improved the correlation between LLM-as-Judge and expert evaluations, as measured by Cohen’s kappa, from 0.226 (slight reliability) to 0.539 (moderate reliability).”
Quote in the paperSubstantial claim- Rests on an assumption: The 30 expert-designed criteria cover the relevant aspects of USMLE question quality.
- Findingown data
GPT-4 plus MCQG-SRefine outperformed GPT-4 on all five components evaluated by LLM-as-judge rating.
“Notably, GPT-4 + MCQG-SRefine consistently outperformed GPT-4 across all five evaluated components with LLM-as-judge (Rating) results rather than demonstrating an advantage in only a single aspect12.”
Quote in the paperSubstantial claim- Rests on an assumption: The 30 expert-designed criteria cover the relevant aspects of USMLE question quality.
- Findingown data
For machine-generated topics and key points, 24.9% of best scores came from the first round.
“We observed similar results for machine-generated topics and key points, but the proportion of best scores from the first round was lower (24.9%).”
Quote in the paperNot a substantial claim - Findingown data
MCQG-SRefine showed improvements across 10 criteria within 5 components, not only in one area.
“Moreover, MCQG-SRefine demonstrated overall improvements across 10 criteria within the 5 components, not just in a specific area.”
Quote in the paperSubstantial claim- Rests on an assumption: The 30 expert-designed criteria cover the relevant aspects of USMLE question quality.
- Findingown data
Human evaluation preferred MCQG-SRefine questions over GPT-4 questions with 72.5% wins, 10% ties, and 17.5% losses.
“Human evaluations confirm its effectiveness, showing a strong preference for MCQG-SRefine generated questions, with a preference ratio of 72.5% in win, 10% tie, and 17.5% loss when compared to GPT-4 generated questions.”
Quote in the paperSubstantial claim - Findingown data
GPT-4 was chosen for its comparatively lower position bias relative to Claude3-Opus, Sonnet, Haiku, and GPT-3.5.
“while GPT-4 was selected due to its relatively smaller position bias compared to other models such as Claude3-Opus, Sonnet, Haiku, and GPT-3.5 (as shown in Appendix Table 19)”
Quote in the paperSubstantial claim - Findingown data
After aspect filtering, the percentage agreement and Cohen's kappa of LLM-as-Judge improved significantly.
“In Table 2, we observed that the percentage agreement and Cohen’s kappa of LLM-as-Judge significantly improved16.”
Quote in the paperSubstantial claim- Rests on an assumption: The 30 expert-designed criteria cover the relevant aspects of USMLE question quality.
- Findingown data
GPT-4 plus MCQG-SRefine had a 70-80% win rate over GPT-4 in human preference for question quality.
“Figure 3 demonstrates the over-whelming advantage of GPT-4 + MCQG-SRefine over GPT-4 with a 70–80% win rate in human preference about question quality (RQ1).”
Quote in the paperSubstantial claim - Findingown data
GPT-4 plus MCQG-SRefine generated more concise questions than GPT-4.
“Another finding is that the questions generated by GPT-4 + MCQG-SRefine are more concise compared to those by GPT-4 (Case Study 1).”
Quote in the paperNot a substantial claim - Findingown data
Automated LLM-as-Judge evaluation showed that MCQG-SRefine questions were preferred over GPT-4 questions at 79.97% versus 20.03%.
“Using the results from this automated evaluation system, it was shown that the preference rate for questions generated by MCQG-SRefine over those generated by GPT-4 was 79.97% in favor and 20.03% against.”
Quote in the paperSubstantial claim- Rests on an assumption: The 30 expert-designed criteria cover the relevant aspects of USMLE question quality.
- Findingown data
GPT-4 generated questions often reveal the correct answer or obvious keywords in the context.
“One of the main issues with the questions generated by GPT-4 is that they often directly include the correct answer or too obvious relevant keywords within the context component (Appendix Table 20 Case Studies 1 and 3).”
Quote in the paperSubstantial claim - Findingown data
For human-provided topics and key points, GPT-4 plus MCQG-SRefine had a 79.8% win rate versus 20.2% for GPT-4 under LLM-as-judge.
“For human-provided topics and key point cases, GPT-4 + MCQG-SRefine achieved a win rate of 79.8% compared to 20.2% for GPT-4.”
Quote in the paperSubstantial claim- Rests on an assumption: The 30 expert-designed criteria cover the relevant aspects of USMLE question quality.
- Findingown data
Human assessment found factual errors in 7.5% of GPT-4 generated problems.
“our human assessment shows that 7.5% of GPT-4 problems contain factual errors”
Quote in the paperSubstantial claim - Findingown data
In some instances, later refinement rounds performed no better than earlier ones.
“we observed cases where later refinements did not outperform earlier ones.”
Quote in the paperSubstantial claim - Findingown data
Using the critique criteria from MCQG-SRefine directly for LLM-as-Judge correlated only slightly with Expert X's human evaluation.
“Regarding the evaluation criteria for each part of the MCQ, we found that directly using the criteria from the critique section of MCQG-SRefine did not correlate well with the human evaluation results of Expert X.”
Quote in the paperSubstantial claim- Rests on an assumption: The 30 expert-designed criteria cover the relevant aspects of USMLE question quality.
- Findingown data
The All-Combo method identified the optimal combination of aspects for LLM-as-Judge.
“As shown in Appendix Table 25 and Table 26, the All-Combo method identified the optimal aspect combination.”
Quote in the paperSubstantial claim- Rests on an assumption: The 30 expert-designed criteria cover the relevant aspects of USMLE question quality.
- Findingnone given
Even after expert-designed prompts, tailored topics and test points, and step-by-step retrieval and generation, the INIT step's LLM-generated USMLE MCQs still did not reach the required quality and difficulty.
“the LLM-generated USMLE MCQs in the INIT step still fall short of the required quality and difficulty.”
Quote in the paperSubstantial claim - Findingown data
MCQG-SRefine, which combines expert prompt engineering with iterative self-critique and self-correction, increases human expert satisfaction with question quality and difficulty.
“By integrating expert-driven prompt engineering with iterative self-critique and self-correction feedback, MCQG-SRefine significantly enhances human expert satisfaction regarding both the quality and difficulty of the questions.”
Quote in the paperSubstantial claim - Findingown data
Prompt engineering did not resolve GPT-4's conservative copying issue.
“We also found that prompt engineering was ineffective in resolving this issue.”
Quote in the paperSubstantial claim - Findingown data
For machine-provided topics and key points, GPT-4 plus MCQG-SRefine had an 80.1% win rate versus 19.9% for GPT-4 under LLM-as-judge.
“Similarly, for machine-provided topics and key point cases, GPT-4 + MCQG-SRefine achieved a win rate of 80.1%, outperforming GPT-4’s 19.9%.”
Quote in the paperSubstantial claim- Rests on an assumption: The 30 expert-designed criteria cover the relevant aspects of USMLE question quality.
- Findingown data
MCQG-SRefine generated questions had 5% factual errors.
“MCQG-SRefine maintains a high level of factual accuracy (with 5% factual errors)”
Quote in the paperSubstantial claim - Interpretationreasoning
Using GPT-4 for both generation and evaluation in the LLM-as-Judge setup introduces a substantial risk of self-evaluation bias.
“The LLM-as-Judge approach, where GPT-4 is used for both generating and evaluating output, carries a significant risk of self-evaluation bias.”
Quote in the paperSubstantial claim - Premisecitation
According to higher-order thinking theories in education, evaluation is cognitively more demanding than task completion.
“According to higher-order thinking theories17 in educational research, evaluation is a cognitively higher-dimensional task compared to task completion.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites higher-order thinking theories17
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Interpretationown data
The LLM cannot consistently ensure that its critiques and corrections will keep improving generated question quality.
“This suggests that the LLM cannot consistently ensure that its critique and corrections will continuously improve the quality of the generated questions.”
Quote in the paperSubstantial claim - Interpretationown data
Choosing the best round after multiple iterations generally yields much higher final question quality than the initial output.
“However, based on the main results, selecting the best round after multiple iterations generally leads to a much higher quality of final questions compared to the initial output.”
Quote in the paperSubstantial claim - Interpretationown data
MCQG-SRefine is effective at making generated questions more difficult.
“This demonstrates the effectiveness of MCQG-SRefine in increasing the difficulty of questions.”
Quote in the paperSubstantial claim - Interpretationreasoning
MCQG-SRefine enhances an LLM's capacity to produce high-quality USMLE-style MCQs by combining expert-driven prompts with iterative self-refinement.
“In conclusion, MCQG-SRefine improves LLM ability to generate high-quality USMLE-style MCQs by integrating expert-driven prompts with iterative self-refinement.”
Quote in the paperSubstantial claim - Interpretationreasoning
The authors' LLM-as-Judge measure provides a scalable substitute for expensive expert evaluations.
“Additionally, our LLM-as-Judge metric offers a scalable alternative to costly expert assessments.”
Quote in the paperNot a substantial claim - Interpretationreasoning
The choice of topics and test points strongly affects the quality and difficulty of generated USMLE questions.
“Therefore, the quality and difficulty of the generated USMLE questions are significantly influenced by the selection of topics t and test points k.”
Quote in the paperSubstantial claim - Premisecitation
LLM-as-judge research has concentrated largely on general NLP, with little work in specialized areas such as clinical NLP.
“However, most LLM-as-judge research has primarily focused on general NLP fields, with limited exploration in specialized domains like clinical NLP.”
Quote in the paperSubstantial claim - Interpretationnone given
This work is the first to use LLM-as-judge for USMLE-MCQ generation and evaluation.
“To the best of our knowledge, we are the first to explore the application of LLM-as-judge in the context of USMLE-MCQ generation and evaluation.”
Quote in the paperNot a substantial claim - Premisecitation
LLM-as-judge approaches have shown instability in some complex task settings.
“Despite their success, these methods have demonstrated instability in certain complex task scenarios (Wang et al., 2023c; Zhang et al., 2024b).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites Wang et al., 2023c
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Zhang et al., 2024b
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- May combine two claims. 25
- Classified as probably not a substantial claim. 13
- The quote only partly states this claim. 1
May combine two claims.
PremisecitationGenerating questions on specific concepts requires precise prompts, and students may not know how to formulate them.
“Secondly, generating questions on specific concepts requires precise prompts (Limit2), which students might not know how to formulate (Sahoo et al., 2024).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Sahoo et al., 2024 source
The Few-Shot Prompting section (page unavailable) says careful prompt engineering is important for optimal performance, and §2.5 describes crafting effective prompts as laborious even for expert annotators. These passages support the general difficulty of formulating effective prompts, but they do not establish that generating questions on specific concepts requires precise prompts or that students may not know how to formulate them. (LLM, conf=0.82)
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationGPT-4 and similar LLMs have trouble generating professional multiple-choice questions because of outdated training data, hallucination, and prompt sensitivity, which leads to poor quality and difficulty.
“However, current large language models (LLMs) like GPT-4 struggle with professional MCQG due to outdated knowledge, hallucination issues, and prompt sensitivity, resulting in unsatisfactory quality and difficulty.”
- Also stated in: § Introduction · plain
“Firstly, their performance is constrained by their training data, leading to two major issues: outdated knowledge (Mousavi et al., 2024) and hallucination (Zhang et al., 2023) (Limit1).”
Quote in the paperSubstantial claim1 of 3 sources checked- cites Mousavi et al., 2024
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Zhang et al., 2023
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Sahoo et al., 2024 source
The Retrieval Augmented Generation (RAG) section says limited, static training data can hinder accurate LLM responses, and the Chain-of-Knowledge (CoK) Prompting section describes factual hallucinations and unreliable outputs. These support general concerns about LLMs, but the passages do not establish that GPT-4 struggles specifically with professional multiple-choice question generation, that prompt sensitivity causes this problem, or that the resulting questions have unsatisfactory quality and difficulty. No page numbers are available in our copy. (LLM, conf=0.84)
Experimental — accuracy not yet measured
- Also stated in: § Introduction · plain
Classified as probably not a substantial claim. May combine two claims.
PremisecitationNatural language or correction feedback carries more information than preference or fine-grained feedback, making it especially useful for self-correcting language models.
“Unlike preference and fine-grained feedback, which provide scalar values as training signals, natural language or correction feedback offers richer information (Scheurer et al., 2022; Ma et al., 2023; Yao et al., 2023b; Mishra et al., 2024), making it particularly effective for self-correcting language models (Welleck et al., 2022; Pan et al., 2023).”
Quote in the paperSubstantial claim3 of 3 sources checked- cites Scheurer et al., 2022 source
The Abstract and Introduction (p. 1) say natural-language feedback conveys more information per evaluation than pairwise preference comparisons. They do not make the same comparison with fine-grained feedback or characterize it as a scalar training signal. The self-correction claim is attached to different citations in the citing sentence. (LLM, conf=0.82)
Experimental — accuracy not yet measured - cites Welleck et al., 2022 source
- cites Pan et al., 2023 source
May combine two claims.
PremisecitationAlthough LLMs can rapidly produce MCQs, the resulting questions often fall short in quality and difficulty.
“Overall, while LLMs can quickly generate MCQs, their quality and difficulty often do not meet expectations.”
Quote in the paperSubstantial claim2 of 3 sources checked- cites Cheung et al. (2023) source
The Question construction section reports that ChatGPT produced 50 MCQs in 20 minutes 25 seconds, versus 211 minutes 33 seconds for human examiners, supporting the speed claim. But the Assessment of question quality section calls the scores satisfactory and finds no significant AI–human difference in overall quality or the exam-suitability domain, which assessed level of challenge. The claim that quality and difficulty often fall short is not supported by these results. (LLM, conf=0.87)
Experimental — accuracy not yet measured - cites Klang et al. (2023)
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Agarwal et al. (2023) source
The Discussion reports that ChatGPT produced the least difficult MCQs, none of the three models produced many questions requiring high-level reasoning, and Bard and Bing produced questions with quality shortcomings. The study examined MCQs in medical physiology; it did not measure how quickly the models generated them, so the speed claim is unsupported. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Classified as probably not a substantial claim. May combine two claims.
PremisecitationFeedback-based learning helps LLMs align with intended outcomes and improves their instruction-following across various feedback types.
“Learning from feedback helps align LLMs with desired outcomes, enhancing their ability to follow instructions through different forms of feedback, such as human preference feedback (Ouyang et al., 2022), AI-generated preference feedback (Lee et al., 2023; Dubois et al., 2024), or fine-grained feedback (Wu et al., 2024; Lightman et al., 2023).”
Quote in the paperSubstantial claim1 of 3 sources checked- cites Ouyang et al., 2022
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Lee et al., 2023 source
- cites Dubois et al., 2024
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationIn medicine, LLM judges have shown some promise for diagnostic support, documentation, clinical conversation, medical question answering, medical reasoning, and patient education.
“In the medical field (Li et al., 2024c; Raju et al., 2024), LLMs-as-judges have demonstrated certain potential in areas such as diagnostic support (Yao et al., 2024), medical documentation (Brake and Schaaf, 2024,?), clinical conversation (Wang et al., 2023a; Li et al., 2024a), medical question answering (Wang et al., 2024b; Krolik et al., 2024), medical reasoning (Jeong et al., 2024), and patient”
Quote in the paperNot a substantial claim2 of 3 sources checked- cites Li et al., 2024c
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Raju et al., 2024 source
- cites Yao et al., 2024 source
The Method section uses GPT-3.5-turbo as an examiner of medical definitions for patient education, not as a judge for diagnostic support. A References entry names a separate study on imaging diagnostic support, but the searched passages do not report the claimed use of LLM judges in diagnosis. (LLM, conf=0.76)
Experimental — accuracy not yet measured
Classified as probably not a substantial claim. May combine two claims.
PremisecitationSelf-correction typically entails producing a critique of the initial response's weaknesses and then revising it accordingly; this iterative approach has shown potential to improve LLM output quality.
“This self-correction process generally involves generating a critique that identifies shortcomings in the initial response, followed by revising it based on the self-critique—an iterative process that has shown promise in enhancing LLM output quality (Pan et al., 2023).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Pan et al., 2023 source
May combine two claims.
Findingown dataThe proposed framework markedly improves the quality and difficulty of generated questions and shows close agreement with expert assessments.
“The framework significantly enhances question quality and difficulty while aligning closely with expert evaluations.”
- Also stated in: § Potential for Over-Self-Critique: · plain
“Our iterative self-refinement method (MCQG-SRefine) improves question quality and difficulty based on critique and correction stages.”
Quote in the paperSubstantial claim- Also stated in: § Potential for Over-Self-Critique: · plain
May combine two claims.
Findingown dataWhen MCQG-SRefine removed too much information to raise quality and difficulty, inferring the correct answer sometimes became harder, though this was rare (7.5%) in human evaluation.
“However, when MCQG-SRefine reduced the amount of useless information provided in the questions to increase quality and difficulty, omitting too much information sometimes made inferring the correct answer more challenging (Case Study 2), although this was a rare occurrence in our human evaluation (7.5%).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataGPT-4's judgments are inconsistent in about 35% of instances, varying with the order in which options are presented (A-B versus B-A).
“it still exhibits inconsistencies in approximately 35% of cases. These inconsistencies, where GPT-4’s judgments vary based on the order of presented options (A-B vs. B-A), highlight the challenges of relying on LLMs for evaluation.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataWith expert-identified topics and test points, MCQG-SRefine reduced easy questions by 80%, increased medium questions 2.25-fold, and increased hard questions 4-fold.
“Specifically, when provided with expert-identified topics and test points, there is an 80% reduction in easy questions, a 2.25-fold increase in medium questions, and a 4-fold increase in hard questions.”
- Also stated in: § Main results · hedged
“In Figure 4, we also observe a decrease of about 80% in easy questions, a 2.25 times increase in medium questions, and a 4 times increase in hard questions with the input of these medical cases with expert-provided topics and key points.”
Quote in the paperSubstantial claim- Rests on an assumption: The AMBOSS difficulty labels provide a valid reference for USMLE question difficulty.
- Also stated in: § Main results · hedged
May combine two claims.
Findingown dataFor human-generated topics and key points, 30% of best scores came from the first round, while the remaining 70% were evenly spread across rounds 2, 3, and 4.
“For human-generated topics and key points, 30% of the best scores came from the first round of output, while the remaining 70% were evenly distributed across rounds 2, 3, and 4.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataWith machine-provided topics and key points, easy questions fell by 33.3%, medium questions doubled, and hard questions did not increase.
“For machine-provided topics and key point cases, the proportion of easy questions decreased by 33.3%, a 2 times increase in medium questions, but there was no increase in the proportion of hard questions (RQ2).”
Quote in the paperSubstantial claim- Rests on an assumption: The AMBOSS difficulty labels provide a valid reference for USMLE question difficulty.
Probably not a substantial claim: may not pass S4 (based). May combine two claims.
InterpretationreasoningGrounding the key elements of generated questions in the original medical cases helps LLMs reduce hallucinations and improves reliability.
“Additionally, grounding questions’ key elements in the original medical cases can help LLMs reduce hallucinations, enhancing the reliability of the generated content.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataHuman-provided topics and key points were clearer, making high-quality first-round generation more likely, while machine-provided ones needed more improvement.
“This is consistent with the main results, where topics and key points provided by humans were clearer, making it more likely for the LLM to generate high-quality questions in the first round, while those provided by machines required more improvement.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
InterpretationreasoningIf LLMs are not given targeted guidance like chosen topics and test points, their questions frequently miss relevance, quality, and suitable difficulty.
“As discussed in Limit2, generating questions using LLMs without specific guidance, such as defined topics t and test points k, often results in questions that lack relevance, quality, and appropriate difficulty.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Study design and conductown dataHuman evaluators did not know which system generated each question, and question order was randomized per data point.
“The evaluators were blinded to the source of the questions, and the order of the questions was randomized for each data point.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationGenerative AI models may create content well without deep understanding, reducing their dependability as evaluators.
“Recent studies (West et al., 2023) also reveal that generative AI models can excel at creating content while lacking deep understanding, which limits their reliability as evaluators.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites West et al., 2023
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
PremisecitationGPT-4 and similar LLMs perform very well on USMLE QA tasks, reaching human-expert accuracy and reasoning.
“Our motivation stems from the fact that LLMs like GPT-4 have proven to perform exceptionally well on USMLE QA tasks, achieving human-expert levels in both accuracy and reasoning processes.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Achiam et al., 2023
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
InterpretationreasoningUsing recent medical cases as input lets LLMs generate more up-to-date questions and reduces the outdated-knowledge limitation.
“Using the latest medical cases as input, LLMs can generate up-to-date questions, thereby minimizing the limitations of outdated knowledge.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataAn LLM-as-Judge automatic metric can replace costly expert evaluation and provide reliable, expert-aligned assessments.
“Furthermore, we introduce an LLM-as-Judge-based automatic metric to replace the complex and costly expert evaluation process, ensuring reliable and expert-aligned assessments.”
Quote in the paperSubstantial claim- Rests on an assumption: The 30 expert-designed criteria cover the relevant aspects of USMLE question quality.
May combine two claims. The quote only partly states this claim.
Interpretationown dataGPT-4 used a conservative strategy of copying and pasting from raw medical cases to avoid hallucination, which sacrificed simplicity and logical coherence.
“Our experiments show that GPT-4 adopted a very conservative strategy when generating context due to our emphasis on hallucination issues in the prompts. This strategy involves copying and pasting much information from raw medical case inputs to avoid generating potentially incorrect new facts.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductown dataThe two human evaluators' preference agreement was 87.5% with Cohen's kappa 0.66722, indicating substantial reliability.
“We calculated the Percentage Agreement (87.5%) and Cohen’s kappa (0.66722) for the two evaluators’ preferences, indicating substantial reliability of our human evaluation settings.”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataGPT-4 plus MCQG-SRefine can turn answer-revealing information into hints through critique and correction, which experts judged as better question construction.
“So the questions directly generated by GPT-4 often make the answers obvious, but GPT-4 + MCQG-SRefine can modify this information into hints for the correct answer through its critical and corrective steps, which experts consider a better way to construct questions for candidates (Case Study 4).”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationTop LLMs such as GPT-4 have achieved over 90% accuracy on sample USMLE questions.
“Top LLMs like GPT-4 have shown over 90% accuracy on sample USMLE questions (Achiam et al., 2023).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Achiam et al., 2023
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
Interpretationown dataExpert-provided topics and key points are higher quality than machine-provided ones, allowing the LLM to generate harder questions through deeper critique and correction.
“This also indicates that the quality of topics and key points provided by experts is higher, so LLM can generate more difficult questions by thinking more deeply during the critique and correction steps.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenThis work is the first to apply iterative self-refinement to the generation of USMLE-style MCQs.
“Inspired by the success of these iterative self-refinement methods, we are the first to explore using this approach for generating USMLE-style MCQs.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationStrong LLM reviewers like GPT-4 reach more than 80% agreement with human preferences in multi-turn dialogue, in both controlled and crowd-sourced settings, matching human evaluator agreement levels.
“Similarly, research by Zheng et al. (2024) and Zhang et al. (2024a) indicates that powerful LLM reviewers, such as GPT-4, achieve over 80% consistency with human preferences in multi-turn dialogue scenarios, both in controlled and crowd-sourced settings, reaching agreement levels similar to human evaluators.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites Zheng et al. (2024)
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Zhang et al. (2024a)
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationIn tasks like summarization and story generation, LLM evaluations correlate strongly with human judgments, scoring or comparing texts along specific criteria.
“LLMs have shown a high correlation with human evaluations in tasks such as summarization and story generation, effectively scoring candidate texts or comparing them based on specific evaluation aspects (Chen et al., 2023a; Li et al., 2024c,b; Gu et al., 2024).”
Quote in the paperNot a substantial claim0 of 3 sources checked- cites Chen et al., 2023a
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Li et al., 2024c,b
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Gu et al., 2024
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S4 (based).
Interpretationnone givenThe authors' work tackles these challenges to produce dependable, domain-specific evaluations suited to medical education.
“Our work addresses these challenges to create reliable, domain-specific evaluations that meet the unique requirements of medical education.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
PremisecitationLLMs are able to revise their own outputs to satisfy diverse user requirements, including reducing harmful content, adding keywords, generating diverse responses, or debugging code.
“Recent research has demonstrated that LLMs (Achiam et al., 2023; Heng et al., 2024; Wang et al., 2024a) can self-correct their responses to meet various user requirements, such as reducing harmful content, incorporating specific keywords, diversity requirement generation, or debugging code (Madaan et al., 2024; Chen et al., 2023b).”
Quote in the paperSubstantial claim0 of 3 sources checked- cites Achiam et al., 2023
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Madaan et al., 2024
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Chen et al., 2023b
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
The paper relies on this without support.
The 41 NBME target topics cover all potential exam areas.
“we follow the National Board of Medical Examiners (NBME) guidelines2 to establish a checklist of 41 target topics covering all potential exam areas.”
The paper relies on this without support.
The AMBOSS difficulty labels provide a valid reference for USMLE question difficulty.
“Specifically, we randomly selected 50 real-world USMLE-style questions from the AMBOSS10 dataset (10 for each difficulty level) as examples for the experts to reference.”
“AMBOSS categorizes question difficulty from 1 to 5, where 1 is the easiest and 5 is the most difficult.”
The paper relies on this without support.
The 30 expert-designed criteria cover the relevant aspects of USMLE question quality.
“We used 30 criteria designed by experts in their human evaluation, covering different aspects of USMLE questions, to guide LLM-as-Judge in providing rating or comparison feedback on different systems’ questions.”
The paper relies on this without support.
The PMC-Patients medical cases are representative of real-world cases for USMLE-MCQG.
“For the medical cases utilized in the generation of USMLE questions, we used unidentified patient summaries from the PMC-Patients dataset (Zhao et al., 2023).”
Cites
The publisher hasn’t deposited this paper’s reference list.
Research works printed but not linked: 20
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The Evolution of Question Generation: Analyzing the Impact of Large Language Models
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- Authors
- Yao, Z., Parashar, A., Zhou, H., Jang, W. S., Ouyang, F., Yang, Z., & Yu, H.
- Affiliations
- University of Massachusetts Amherst (US)
- University of Minnesota (US)
- University of Massachusetts Lowell (US)
- Venue
- Proceedings of the 2025 Conference of the Nations of the Americas Chapter of the Association for Computational Linguistics: Human Language Technologies (Volume 1: Long Papers)
- Published
- 2025
- Volume
- 2025
- Pages
- 10728-10777
- PMC
- PMC12889009
- OpenAlex
- W4411120128
- Cited by
- 12
- References
- 0
- Citations by year
- 2026: 9 · 2025: 3
- FWCI
- 12.97
- Type
- conference paper
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Conference of the Nations of the Americas Chapter of the Association for Computational Linguistics: Human Language Technologies (NAACL) (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (submittedVersion)
- PubMed Central (submittedVersion)
- Topics
- Physical Sciences › Computer Science › Artificial Intelligence › Topic Modeling
- Physical Sciences › Computer Science › Artificial Intelligence › Natural Language Processing Techniques
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Keywords
- multiple-choice question generation, automatic question generation, self-refinement, LLM-as-a-judge, USMLE, prompt engineering, hallucinations, question difficulty
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-07.
Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-07.
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