The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Effects of Oral Flora on Platelets: Possible Consequences in Cardiovascular Disease
Abstract
D uring episodes of dental bacteremia, viridans group streptococci encounter platelets. Among these microorganisms, certain Streptococcus sanguis induce human and rabbit platelets to aggregate in vitro. In experimental rabbits, circulating streptococci induced platelets to aggregate, triggering the accumulation of platelets and fibrin into the heart valve vegetations of endocarditis. At necropsy, affected rabbit hearts showed ischemie areas. We therefore hypothesized that circulating S. sanguis might cause coronary thrombosis and signs of myocardial infarction (MI). Signs of MI were monitored in rabbits after infusion with platelet‐aggregating doses of 4 to 40 × 10 9 cells of S. sanguis 133‐79. Infusion resulted in dose‐dependent changes in electrocardiograms, blood pressure, heart rate, and cardiac contractility. These changes were consistent with the occurrence of MI. Platelets isolated from hyperlipidemic rabbits showed an accelerated in vitro aggregation response to strain 133‐79. Cultured from immunosuppressed children with septic shock and signs of disseminated intravascular coagulation, more than 60% of isolates of viridans streptococci induced platelet aggregation when tested in vitro. The data are consistent with a thrombogenic role for S. sanguis in human disease, contributing to the development of the vegetative lesion in infective endocarditis and a thrombotic mechanism to explain the additional contributed risk of periodontitis to MI. J Periodontol 1996;67:1138–1142.
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Cites
Prevalence of Total Coronary Occlusion during the Early Hours of Transmural Myocardial Infarction
DeWood, M. A., Spores, J., Notske, R., Mouser, L. T., Burroughs, R., Golden, M. S., & Lang, H. T. (1980) · New England Journal of Medicine · doi:10.1056/nejm198010163031601 · Cited by 2,740
Periodontal Disease and Cardiovascular Disease
Beck, J., Garcia, R., Heiss, G., Vokonas, P. S., & Offenbachet, S. (1996) · Journal of Periodontology · doi:10.1902/jop.1996.67.10.1123 · Cited by 1,458
Association between dental health and acute myocardial infarction.
Mattila, K. J., Nieminen, M. S., Valtonen, V. V., Rasi, V. P., Kesäniemi, Y. A., Syrjälä, S. L., Jungell, P. S., Isoluoma, M., Hietaniemi, K., & Jokinen, M. J. (1989) · BMJ · doi:10.1136/bmj.298.6676.779 · Cited by 1,059
Prevention of Infective Endocarditis
Durack, D. T. (1995) · New England Journal of Medicine · doi:10.1056/nejm199501053320107 · Cited by 411
Evidence for invasion of a human oral cell line by Actinobacillus actinomycetemcomitans
Meyer, D. H., Sreenivasan, P. K., & Fives-Taylor, P. M. (1991) · Infection and Immunity · doi:10.1128/iai.59.8.2719-2726.1991 · Cited by 202
Aggregation of human platelets and adhesion of Streptococcus sanguis
Herzberg, M. C., Brintzenhofe, K. L., & Clawson, C. C. (1983) · Infection and Immunity · doi:10.1128/iai.39.3.1457-1469.1983 · Cited by 140
Self-citationHerzberg, M. C., MacFarlane, G. D., Gong, K., Armstrong, N. N., Witt, A., Erickson, P. R., & Meyer, M. W. (1992) · Infection and Immunity · doi:10.1128/iai.60.11.4809-4818.1992 · Cited by 139
Self-citationInteraction of Porphyromonas gingivalis with gingival epithelial cells maintained in culture.
Lamont, R. J., Odo, D., Persson, R. E., & Persson, G. R. (1992) · Oral Microbiology and Immunology · doi:10.1111/j.1399-302x.1992.tb00637.x · Cited by 100
Trends in Nonfatal Coronary Heart Disease in the United States, 1980 Through 1989
Destefano, F. R. (1993) · Archives of Internal Medicine · doi:10.1001/archinte.1993.00410210117013 · Cited by 65
Cited by
Identification of Periodontal Pathogens in Atheromatous Plaques
Haraszthy, V. I., Zambon, J. J., Trevisan, M., Zeid, M., & Genco, R. J. (2000) · Journal of Periodontology · doi:10.1902/jop.2000.71.10.1554 · Cited by 1,120
Porphyromonas gingivalis: An Overview of Periodontopathic Pathogen below the Gum Line
How, K. Y., Song, K. P., & Chan, K. G. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00053 · Cited by 858
Association between periodontal pathogens and systemic disease
Bui, F. Q., Almeida-da-Silva, C. L. C., Huynh, B., Trinh, A., Liu, J., Woodward, J., Asadi, H., & Ojcius, D. M. (2019) · Biomedical Journal · doi:10.1016/j.bj.2018.12.001 · Cited by 829
Systemic Diseases Caused by Oral Infection
Li, X., Kolltveit, K. M., Tronstad, L., & Olsen, I. (2000) · Clinical Microbiology Reviews · doi:10.1128/cmr.13.4.547 · Cited by 1,292
Bahekar, A. A., Singh, S., Saha, S., Molnar, J., & Arora, R. (2007) · American Heart Journal · doi:10.1016/j.ahj.2007.06.037 · Cited by 698
Metadata
- Authors
- Herzberg, M. C., & Meyer, M. W.
- Venue
- Journal of Periodontology
- Publisher
- Wiley
- Published
- 1996-10
- Volume
- 67
- Issue
- 10S
- Pages
- 1138-1142
- ISSN
- 0022-3492 (ISSN-L)
- 1943-3670
- OpenAlex
- W2063831637
- Cited by
- 260
- References
- 9
- FWCI
- 10.34
- Type
- journal article
- Language
- en
- Open access
- closed
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