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The RE-AIM Framework: A Systematic Review of Use Over Time
Open accessAbstract
We provided a synthesis of use, summarized key issues in applying, and highlighted exemplary applications in the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework. We articulated key RE-AIM criteria by reviewing the published literature from 1999 to 2010 in several databases to describe the application and reporting on various RE-AIM dimensions. After excluding nonempirical articles, case studies, and commentaries, 71 articles were identified. The most frequent publications were on physical activity, obesity, and disease management. Four articles reported solely on 1 dimension compared with 44 articles that reported on all 5 dimensions of the framework. RE-AIM was broadly applied, but several criteria were not reported consistently.
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“Literature reviews on the applications of popular implementation frameworks, such as the RE-AIM and the CFIR, have enabled their advancement in implementation science.”
From The NASSS (Non-Adoption, Abandonment, Scale-Up, Spread and Sustainability) framework use over time: A scoping review (2025) · cites this paper as [14]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
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“These reviews have described and assessed the application of the RE-AIM, enabling its advancement (e.g., the enhanced RE-AIM/Pragmatic Robust Implementation and Sustainability Model (PRISM) 2019) and novel applications, such as combining the RE-AIM with the Pragmatic Explanatory Continuum Indicator Summary (PRECIS) model [14,15].”
From The NASSS (Non-Adoption, Abandonment, Scale-Up, Spread and Sustainability) framework use over time: A scoping review (2025) · cites this paper as [14]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The applications of popular implementation theories, models, and frameworks (TMFs), such as the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) and the Consolidated Framework for Implementation Research (CFIR), have been well documented in the literature.”
From The NASSS (Non-Adoption, Abandonment, Scale-Up, Spread and Sustainability) framework use over time: A scoping review (2025) · cites this paper as [14]
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“For example, several literature reviews have been written on the RE-AIM since its inception in 1999 [14,15].”
From The NASSS (Non-Adoption, Abandonment, Scale-Up, Spread and Sustainability) framework use over time: A scoping review (2025) · cites this paper as [14]
In the citing paper
“According to the RE-AIM evaluation,21 during this pilot process evaluation, our pathway presented a moderate reach, with moderate to high acceptance rates.”
From Implementing a PROACTive Care Pathway to Empower and Support Survivors of Breast Cancer (2023) · cites this paper as [21]
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Furthering Dissemination and Implementation Research
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Metadata
- Authors
- Gaglio, B., Shoup, J. A., & Glasgow, R. E.
- Affiliations
- Kaiser Permanente (US)
- Venue
- American Journal of Public Health
- Publisher
- American Public Health Association
- Published
- 2013-06
- Volume
- 103
- Issue
- 6
- Pages
- e38-e46
- ISSN
- 0090-0036 (ISSN-L)
- 1541-0048
- PMC
- PMC3698732
- OpenAlex
- W2028764578
- Cited by
- 1,029
- References
- 31
- Citations by year
- 2026: 73 · 2025: 104 · 2024: 107 · 2023: 84 · 2022: 131 · 2021: 139 · 2020: 109 · 2019: 87 · 2018: 61 · 2017: 34 · 2016: 32 · 2015: 33 · 2014: 28 · 2013: 7
- FWCI
- 3.87
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Public Health (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Health Research Board
- National Cancer Institute
- Topics
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Social Sciences › Public Administration › Evaluation and Performance Assessment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Public Health Policies and Education
- Keywords
- RE-AIM framework, implementation research, REACH regulation, effectiveness, adoption, implementation, maintenance, physical activity interventions, obesity intervention, reporting consistency
- MeSH terms
- Health Promotion, Humans, Program Evaluation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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