The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.
Role of inflammatory cells in airway remodeling in COPD
Open accessAbstract
COPD is characterized by chronic bronchitis, chronic airway obstruction, and emphysema, leading to a progressive and irreversible decline in lung function. Inflammation is central for the development of COPD. Chronic inflammation in COPD mainly involves the infiltration of neutrophils, macrophages, lymphocytes, and other inflammatory cells into the small airways. The contribution of resident airway structural cells to the inflammatory process is also important in COPD. Airway remodeling consists of detrimental changes in structural tissues and cells including airway wall thickening, epithelial metaplasia, goblet cell hypertrophy, and smooth muscle hyperplasia. Persistent airway inflammation might contribute to airway remodeling and small airway obstruction. However, the underlying mechanisms remain unclear. In this review, we will provide an overview of recent insights into the role of major immunoinflammatory cells in COPD airway remodeling.
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The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
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Asthma: From Bronchoconstriction to Airways Inflammation and Remodeling
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Remodeling in Asthma and Chronic Obstructive Lung Disease
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The Pathology of Chronic Obstructive Pulmonary Disease
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New insights into the immunology of chronic obstructive pulmonary disease
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Self-citation
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Oxidative Stress and Inflammation in Acute and Chronic Lung Injuries
Bezerra, F. S., Lanzetti, M., Nesi, R. T., Nagato, A. C., Silva, C. P. E., Kennedy-Feitosa, E., Melo, A. C., Cattani-Cavalieri, I., Porto, L. C., & Valenca, S. S. (2023) · Antioxidants · doi:10.3390/antiox12030548 · Cited by 336
Pathogenesis of chronic obstructive pulmonary disease (COPD) induced by cigarette smoke
Hikichi, M., Mizumura, K., Maruoka, S., & Gon, Y. (2019) · Journal of Thoracic Disease · doi:10.21037/jtd.2019.10.43 · Cited by 283
p21 facilitates chronic lung inflammation via epithelial and endothelial cells
Levi, N., Papismadov, N., Majewska, J., Roitman, L., Wigoda, N., Eilam, R., Tsoory, M., Rotkopf, R., Ovadya, Y., Akiva, H., et al. (2023) · Aging · doi:10.18632/aging.204622 · Cited by 15
Metadata
- Authors
- Wang, Y., Xu, J., Meng, Y., Adcock, I. M., & Yao, X.
- Venue
- International Journal of Chronic Obstructive Pulmonary Disease
- Publisher
- Informa UK Limited
- Published
- 2018-10
- Volume
- Volume 13
- Pages
- 3341-3348
- ISSN
- 1176-9106 (ISSN-L)
- 1178-2005
- OpenAlex
- W2895954347
- Cited by
- 373
- References
- 83
- FWCI
- 15.73
- Type
- journal article
- Language
- en
- Open access
- gold
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- Wang, Y., Xu, J., Meng, Y., Adcock, I. M., & Yao, X. (2018). Role of inflammatory cells in airway remodeling in COPD. International Journal of Chronic Obstructive Pulmonary Disease. https://doi.org/10.2147/copd.s176122
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
