Metabonomics reveals peripheral and central short-chain fatty acid and amino acid dysfunction in a naturally occurring depressive model of macaques

Causal analysis approaches in Ingenuity Pathway Analysis

Krämer, A., Green, J., Pollard, J., & Tugendreich, S. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btt703 · Cited by 5,724 · see citing works

Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism

Zheng, P., Zeng, B., Zhou, C., Liu, M., Fang, Z., Xu, X., Zeng, L., Chen, J., Fan, S., Du, X., et al. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.44 · Cited by 2,023 · see citing works

Using MetaboAnalyst 3.0 for Comprehensive Metabolomics Data Analysis

Xia, J., & Wishart, D. S. (2016) · Current Protocols in Bioinformatics · doi:10.1002/cpbi.11 · Cited by 1,537 · see citing works

The microbiology of butyrate formation in the human colon

Pryde, S. E., Duncan, S. H., Hold, G. L., Stewart, C. S., & Flint, H. J. (2002) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2002.tb11467.x · Cited by 1,320 · see citing works

TagFinder for the quantitative analysis of gas chromatography—mass spectrometry (GC-MS)-based metabolite profiling experiments

Luedemann, A., Strassburg, K., Erban, A., & Kopka, J. (2008) · Bioinformatics · doi:10.1093/bioinformatics/btn023 · Cited by 547 · see citing works

Lipid Alterations in Lipid Rafts from Alzheimer's Disease Human Brain Cortex

Martín, M. V., Fabelo, N., Santpere, G., Puig, B., Marín, R., Ferrer, I., & Díaz, M. L. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-1242 · Cited by 269 · see citing works

Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium

Zhang, Q., Wu, Y., Wang, J., Wu, G. G., Long, W., Xue, Z., Wang, L., Zhang, X., Pang, X., Zhao, Y., et al. (2016) · Scientific Reports · doi:10.1038/srep27572 · Cited by 229 · see citing works

Identification and Validation of Urinary Metabolite Biomarkers for Major Depressive Disorder

Zheng, P., Wang, Y., Chen, L., Yang, D., Meng, H., Zhou, D., Zhong, J., Lei, Y., Melgiri, N. D., & Xie, P. (2012) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m112.021816 · Cited by 198 · see citing works

tRNA synthetase: tRNA aminoacylation and beyond

Pang, Y. L. J., Poruri, K., & Martinis, S. A. (2014) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1224 · Cited by 166 · see citing works

Low Cerebrospinal Fluid Glutamate and Glycine in Refractory Affective Disorder

Frye, M. A., Tsai, G. E., Huggins, T., Coyle, J. T., & Post, R. M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.01.024 · Cited by 149 · see citing works

Dopamine’s Actions in Primate Prefrontal Cortex: Challenges for Treating Cognitive Disorders

Arnsten, A. F. T., Wang, M., & Paspalas, C. D. (2015) · Pharmacological Reviews · doi:10.1124/pr.115.010512 · Cited by 149 · see citing works

The biological significance of brain barrier mechanisms: help or hindrance in drug delivery to the central nervous system?

Saunders, N. R., Habgood, M. D., Møllgård, K., & Dziegielewska, K. M. (2016) · F1000Research · doi:10.12688/f1000research.7378.1 · Cited by 143 · see citing works

NMR‐based metabolomic analysis of cerebrospinal fluid and serum in neurological diseases – a diagnostic tool?

Sinclair, A. J., Viant, M. R., Ball, A. K., Burdon, M., Walker, E. A., Stewart, P. M., Rauz, S., & Young, S. P. (2009) · NMR in Biomedicine · doi:10.1002/nbm.1428 · Cited by 134 · see citing works

Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis

Yoshimi, N., Futamura, T., Bergen, S. E., Iwayama, Y., Ishima, T., Sellgren, C. M., Ekman, C. J., Jakobsson, J., Pålsson, E., Kakumoto, K., et al. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.217 · Cited by 110 · see citing works

Comparative proteomic analysis of plasma from major depressive patients: identification of proteins associated with lipid metabolism and immunoregulation

Xu, H., Zhang, R.-F., Luo, D., Zhou, Y., Wang, Y., Fang, L., Li, W., Mu, J., Zhang, L., Zhang, Y., et al. (2012) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145712000302 · Cited by 102 · see citing works

Age- and Sex-Based Hematological and Biochemical Parameters for Macaca fascicularis

Xie, L., Xu, F., Liu, S., Ji, Y., Zhou, Q., Wu, Q., Gong, W., Cheng, K., Li, J., Li, L., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064892 · Cited by 84 · see citing works

Targeted Metabolomic Pathway Analysis and Validation Revealed Glutamatergic Disorder in the Prefrontal Cortex among the Chronic Social Defeat Stress Mice Model of Depression

Wang, W., Guo, H., Zhang, S., Li, J., Cheng, K., Bai, S., Yang, D., Wang, H., Liang, Z., Liao, L., et al. (2016) · Journal of Proteome Research · doi:10.1021/acs.jproteome.6b00577 · Cited by 84 · see citing works

Amino acid metabolic dysfunction revealed in the prefrontal cortex of a rat model of depression

Chen, G., Yang, D., Yang, Y., Li, J., Cheng, K., Tang, G., Zhang, R., Zhou, J., Li, W., Liu, Z., et al. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.05.027 · Cited by 77 · see citing works

Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System

Lochhead, J. J., Ronaldson, P. T., & Davis, T. P. (2017) · The AAPS Journal · doi:10.1208/s12248-017-0076-6 · Cited by 77 · see citing works

Divergent Urinary Metabolic Phenotypes between Major Depressive Disorder and Bipolar Disorder Identified by a Combined GC–MS and NMR Spectroscopic Metabonomic Approach

Chen, J., Zhou, C., Liu, Z., Fu, Y., Zheng, P., Yang, D., Li, Q., Mu, J., Wei, Y.-D., Zhou, J., et al. (2015) · Journal of Proteome Research · doi:10.1021/acs.jproteome.5b00434 · Cited by 77 · see citing works

Cerebrospinal Fluid Metabolome in Mood Disorders-Remission State has a Unique Metabolic Profile

Kaddurah-Daouk, R., Yuan, P., Boyle, S. H., Matson, W., Wang, Z., Zeng, Z. B., Zhu, H., Dougherty, G. G., Yao, J. K., Chen, G., et al. (2012) · Scientific Reports · doi:10.1038/srep00667 · Cited by 76 · see citing works

Relationship between central and peripheral fatty acids in humans

Guest, J., Garg, M. L., BILGIN, A. A. B., & Grant, R. (2013) · Lipids in Health and Disease · doi:10.1186/1476-511x-12-79 · Cited by 69 · see citing works

NMR metabonomics of cerebrospinal fluid distinguishes between Parkinson’s disease and controls

Öhman, A., & Forsgren, L. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2015.03.051 · Cited by 69 · see citing works

Supplementation of omega 3 fatty acids may improve hyperactivity, lethargy, and stereotypy in children with autism spectrum disorders: a meta-analysis of randomized controlled trials

Cheng, Y., Tseng, P., Chen, Y., Stubbs, B., Yang, W.-C., Chen, T., Wu, C.-K., & Lin, P. (2017) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s147305 · Cited by 68 · see citing works

On the depressive nature of the “burnout syndrome”: A clarification

Bianchi, R., Schonfeld, I. S., Vandel, P., & Laurent, É. (2017) · European Psychiatry · doi:10.1016/j.eurpsy.2016.10.008 · Cited by 64 · see citing works

Decreased plasma neuroactive amino acids and increased nitric oxide levels in melancholic major depressive disorder

Lu, Y.-R., Fu, X., Shi, L., Jiang, Y., Wu, J., Weng, X.-J., Wang, Z.-P., Wu, X., Lin, Z., Liu, W.-B., et al. (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-123 · Cited by 64 · see citing works

Macaques Exhibit a Naturally-Occurring Depression Similar to Humans

Xu, F., Wu, Q., Xie, L., Gong, W., Zhang, J., Zheng, P., Zhou, Q., Ji, Y., Wang, T., Li, X., et al. (2015) · Scientific Reports · doi:10.1038/srep09220 · Cited by 57 · see citing works

Metabolomics identifies perturbations in amino acid metabolism in the prefrontal cortex of the learned helplessness rat model of depression

Zhou, X., Liu, L., Zhang, Y., Pu, J., Yang, L., Zhou, C., Yuan, S., Zhang, H., & Xie, P. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.11.038 · Cited by 57 · see citing works

Metabolite signature for diagnosing major depressive disorder in peripheral blood mononuclear cells

Zheng, P., Fang, Z., Xu, X., Liu, M., Du, X., Zhang, X., Wang, H., Zhou, J., & Xie, P. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.02.008 · Cited by 55 · see citing works

Metabolomic analysis reveals metabolic disturbances in the prefrontal cortex of the lipopolysaccharide-induced mouse model of depression

Wu, Y. H., Fu, Y., Rao, C., Li, W., Liang, Z., Zhou, C., Shen, P., Cheng, P., Zeng, L., Zhu, D., et al. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.04.032 · Cited by 53 · see citing works

A 1H-NMR plasma metabonomic study of acute and chronic stress models of depression in rats

Shi, B., Tian, J., Xiang, H., Guo, X., Zhang, L., Du, G., & Qin, X. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.11.036 · Cited by 50 · see citing works

Potential clinical utility of plasma amino acid profiling in the detection of major depressive disorder

Xu, H., Fang, L., Hu, Z., Chen, Y., Chen, J., Li, F., Lu, J. Y., Mu, J., & Xie, P. (2012) · Psychiatry Research · doi:10.1016/j.psychres.2012.05.027 · Cited by 49 · see citing works

Depression-Like Behavioral Phenotypes by Social and Social Plus Visual Isolation in the Adult Female Macaca fascicularis

Li, X., Xu, F., Xie, L., Ji, Y., Cheng, K., Zhou, Q., Wang, T., Shively, C. A., Wu, Q., Gong, W., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073293 · Cited by 47 · see citing works

A Peptide/MHCII conformer generated in the presence of exchange peptide is substrate for HLA-DM editing

Ferrante, A., & Gorski, J. (2012) · Scientific Reports · doi:10.1038/srep00386 · Cited by 43 · see citing works

Oleic acid synthesized in the periventricular zone promotes axonogenesis in the striatum during brain development

Polo‐Hernández, E., Castro, F. D., García‐García, A. G., Tabernero, A., & Medina, J. M. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06891.x · Cited by 42 · see citing works

Patients with depression display cytokine levels in serum and cerebrospinal fluid similar to patients with diffuse neurological symptoms without a defined diagnosis

Hestad, K. A., Engedal, K., Whist, J. E., Aukrust, P., Farup, P. G., Mollnes, T. E., & Ueland, T. (2016) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s101925 · Cited by 42 · see citing works

P-Glycoprotein Mediated Efflux Limits the Transport of the Novel Anti-Parkinson's Disease Candidate Drug FLZ across the Physiological and PD Pathological In Vitro BBB Models

Liu, Q., Hou, J., Chen, X., Liu, G.-T., Zhang, D., Sun, H., & Zhang, J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102442 · Cited by 41 · see citing works

Construction and Validation of a Systematic Ethogram of Macaca fascicularis in a Free Enclosure

Xu, F., Xie, L., Li, X., Li, Q., Wang, T., Ji, Y., Kong, F., Zhan, Q., Cheng, K., Fang, L., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037486 · Cited by 34 · see citing works

Metabolite-related antidepressant action of diterpene ginkgolides in the prefrontal cortex

Hu, Q., Shen, P., Bai, S., Dong, M.-X., Liang, Z., Chen, Z., Wang, W., Wang, H., Gui, S., Li, P., et al. (2018) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s161351 · Cited by 32 · see citing works

ABCB6 , ABCB1 and ABCG1 Genetic Polymorphisms and Antidepressant Response of SSRIs in Chinese Depressive Patients

Huang, X., Yu, T., Li, X., Cao, Y., Li, X., Liu, B., Yang, F., Li, W., Zhao, X., Feng, G., et al. (2013) · Pharmacogenomics · doi:10.2217/pgs.13.151 · Cited by 32 · see citing works

GC–MS-based metabolomic study on the antidepressant-like effects of diterpene ginkgolides in mouse hippocampus

Liang, Z., Bai, S., Shen, P., Hu, Q., Wang, X., Dong, M.-X., Wang, W., Li, J., Cheng, K., Zhang, S., et al. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.08.001 · Cited by 29 · see citing works

Effect of living conditions on biochemical and hematological parameters of the cynomolgus monkey

Xie, L., Zhou, Q., Liu, S., Xu, F., Shively, C. A., Wu, Q., Gong, W., Ji, Y., Fang, L., Li, L., et al. (2014) · American Journal of Primatology · doi:10.1002/ajp.22285 · Cited by 26 · see citing works

Importance of ABC Transporters in Drug Development

Benadiba, M., & Maor, Y. (2016) · Current Pharmaceutical Design · doi:10.2174/1381612822666160810120359 · Cited by 25 · see citing works

ATP-binding cassette sub-family F member 1 (ABCF1) is identified as a putative therapeutic target of escitalopram in the inflammatory cytokine pathway

Powell, T. R., Tansey, K. E., Breen, G. D., FARMER, A. E., Craig, I., Uher, R., McGuffin, P., D’Souza, U. M., & Schalkwyk, L. C. (2013) · Journal of Psychopharmacology · doi:10.1177/0269881113490329 · Cited by 24 · see citing works

Comparative efficacy and acceptability of psychotherapies for post-traumatic stress disorder in children and adolescents: Study protocol for a systematic review and network meta-analysis

Zhang, Y., Zhou, X., Yang, L., Hetrick, S. E., Weisz, J. R., Cuijpers, P., Barth, J., Del Giovane, C., Yuan, S., Cohen, D., et al. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-020198 · Cited by 20 · see citing works

Normal Thoracic Radiographic Appearance of the Cynomolgus Monkey (Macaca fascicularis)

Xie, L., Zhou, Q., Liu, S., Wu, Q., Ji, Y., Zhang, L., Xu, F., Gong, W., Melgiri, N. D., & Xie, P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0084599 · Cited by 19 · see citing works

Suicidality and symptoms of anxiety, irritability, and agitation in patients experiencing manic episodes with depressive symptoms: a naturalistic study

Eberhard, J., & Weiller, E. (2016) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s111094 · Cited by 18 · see citing works

Ipsilateral Hippocampal Proteomics Reveals Mitochondrial Antioxidative Stress Impairment in Cortical-Lesioned Chronic Mild Stressed Rats

Pan, J., Liu, H., Zhou, J., Liu, Z., Yang, Y., Peng, Y., You, H., Yang, D., & Xie, P. (2014) · Current Molecular Medicine · doi:10.2174/1566524014666141021143333 · Cited by 17 · see citing works

Neurobiology of Maternal Stress: Role of Social Rank and Central Oxytocin in Hypothalamic–Pituitary Adrenal Axis Modulation

Coplan, J. D., Karim, A., Chandra, P., Germain, G. S., Abdallah, C. G., & Altemus, M. M. (2015) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2015.00100 · Cited by 15 · see citing works

Ginkgo biloba extract and its diterpene ginkgolide constituents ameliorate the metabolic disturbances caused by recombinant tissue plasminogen activator in rat prefrontal cortex

Chen, Z. X., Bai, S., Hu, Q., Shen, P., Wang, T., Liang, Z., Wang, W., Qi, X., & Xie, P. (2018) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s167448 · Cited by 14 · see citing works

An improved technique for cerebrospinal fluid collection of cisterna magna in Rhesus monkeys

Li, X., Han, P., Guo, Y., Sun, H.-Q., Ying, X., & Kang, Y. J. (2015) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2015.04.004 · Cited by 11 · see citing works

Impact of anxiety symptoms on outcomes of depression: an observational study in Asian patients

Haro, J. M., Novick, D., Montgomery, W. S., Aguado, J., & Peng, X. (2016) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s90134 · Cited by 4 · see citing works

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication

Silva, Y. P., Bernardi, A., & Frozza, R. L. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00025 · Cited by 3,043 · see citing works

Short chain fatty acids: Microbial metabolites for gut-brain axis signalling

O’Riordan, K. J., Collins, M., Moloney, G. M., Knox, E. G., Aburto, M. R., Fülling, C., Morley, S. J., Clarke, G. A., Schellekens, H., & Cryan, J. F. (2022) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2022.111572 · Cited by 742 · see citing works

Associations between disordered gut microbiota and changes of neurotransmitters and short-chain fatty acids in depressed mice

Wu, M., Tian, T., Mao, Q., Zou, T., Zhou, C., Xie, J., & Chen, J. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-01038-3 · Cited by 235 · see citing works

The Role of Gut Bacterial Metabolites in Brain Development, Aging and Disease

Tran, S. M.-S., & Mohajeri, M. H. (2021) · Nutrients · doi:10.3390/nu13030732 · Cited by 207 · see citing works

Recent advances in the therapeutic application of short-chain fatty acids (SCFAs): An updated review

Rauf, A., Khalil, A. A., Rahman, U.-U., Khalid, A., Naz, S., Shariati, M. A., Ребезов, М. Б., Zavala, E., de Albuquerque, R. D. D. G., Anwar, S., et al. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1895064 · Cited by 183 · see citing works

Role of the intestinal microbiome, intestinal barrier and psychobiotics in depression

Trzeciak, P., & Herbet, M. (2021) · Nutrients · doi:10.3390/nu13030927 · Cited by 139 · see citing works

The Role of Bacteria and Its Derived Metabolites in Chronic Pain and Depression: Recent Findings and Research Progress

Li, S., Hua, D., Wang, Q., Yang, L., Wang, X., Luo, A., & Yang, C. (2019) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyz061 · Cited by 91 · see citing works

Probiotics and their Metabolites Reduce Oxidative Stress in Middle-Aged Mice

Lin, W., Lin, J., Kuo, Y., Chiang, P.-F. R., & Ho, H.-H. (2022) · Current Microbiology · doi:10.1007/s00284-022-02783-y · Cited by 82 · see citing works

Role of Short-Chain Fatty Acids Produced by Gut Microbiota in Innate Lung Immunity and Pathogenesis of the Heterogeneous Course of Chronic Obstructive Pulmonary Disease

Kotlyarov, S. N. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23094768 · Cited by 74 · see citing works

Metabolomic Biomarkers in Anxiety Disorders

Humer, E. C., Pieh, C., & Probst, T. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21134784 · Cited by 68 · see citing works

Consumption of peanut products improves memory and stress response in healthy adults from the ARISTOTLE study: A 6-month randomized controlled trial

Parilli‐Moser, I., Domínguez‐López, I., Trius‐Soler, M., Castellvı́, M., Bosch, B., Castro‐Barquero, S., Estruch, R., Hurtado‐Barroso, S., & Lamuela-Raventós, R. M. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.09.020 · Cited by 64 · see citing works

Exploring the microbiota-gut-brain axis: impact on brain structure and function

Yassin, L. K., Nakhal, M. M., Alderei, A., Almehairbi, A., Mydeen, A. B., Akour, A. A., & Hamad, M. I. K. (2025) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2025.1504065 · Cited by 60 · see citing works

A Comprehensive Review on Bioavailability, Safety and Antidepressant Potential of Natural Bioactive Components from Tea

Shao, J., Wei, Y., & Wei, X. (2022) · Food Research International · doi:10.1016/j.foodres.2022.111540 · Cited by 58 · see citing works

Role of the gut microbiota in the pathogenesis of endometriosis: a review

Guo, C., & Zhang, C. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1363455 · Cited by 56 · see citing works

Inulin-type fructans and 2’fucosyllactose alter both microbial composition and appear to alleviate stress-induced mood state in a working population compared to placebo (maltodextrin): the EFFICAD Trial, a randomized, controlled trial

Jackson, P. P. J., Wijeyesekera, A., Williams, C. M., Theis, S., Harsselaar, J. V., & Rastall, R. A. (2023) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2023.08.016 · Cited by 48 · see citing works

Anxiolytic- and antidepressant-like effects of Bacillus coagulans Unique IS-2 mediate via reshaping of microbiome gut-brain axis in rats

Satti, S., Palepu, M. S. K., Singh, A. A., Jaiswal, Y., Dash, S. P., Gajula, S. N. R., Chaganti, S., Samanthula, G., Sonti, R., & Dandekar, M. P. (2023) · Neurochemistry International · doi:10.1016/j.neuint.2023.105483 · Cited by 44 · see citing works

Metabolomics in Psychiatric Disorders: What We Learn from Animal Models

Humer, E. C., Probst, T., & Pieh, C. (2020) · Metabolites · doi:10.3390/metabo10020072 · Cited by 44 · see citing works

Nutrition, Microbiota and Role of Gut-Brain Axis in Subjects with Phenylketonuria (PKU): A Review

Verduci, E., Carbone, M. T., Borghi, E., Ottaviano, E., Burlina, A., & Biasucci, G. (2020) · Nutrients · doi:10.3390/nu12113319 · Cited by 41 · see citing works

Xiaoyao San ameliorates high-fat diet-induced anxiety and depression via regulating gut microbiota in mice

Yang, Y., Zhong, Z., Wang, B., & Wang, Y. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113902 · Cited by 42 · see citing works

Different Serotypes of Adeno-Associated Virus Vector- and Lentivirus-Mediated Tropism in Choroid Plexus by Intracerebroventricular Delivery

Chen, X., He, Y., Tian, Y., Wang, Y., Wu, Z., Lan, T., Wang, H., Cheng, K., & Xie, P. P. (2020) · Human Gene Therapy · doi:10.1089/hum.2019.300 · Cited by 38 · see citing works

Exploring the interplay between posttraumatic stress disorder, gut microbiota, and inflammatory biomarkers: a comprehensive meta-analysis

Petakh, P., Oksenych, V., Kamyshna, I. I., Boisak, I., Lyubomirskaya, K., & Kamyshnyi, O. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1349883 · Cited by 36 · see citing works

The gut microbiota and microbial metabolites are associated with tail biting in pigs

Verbeek, E., Keeling, L. J., Landberg, R., Lindberg, J. E., & Dicksved, J. (2021) · Scientific Reports · doi:10.1038/s41598-021-99741-8 · Cited by 34 · see citing works

Associations between short-chain fatty acid levels and mood disorder symptoms: a systematic review

Bruun, C. F., Hansen, T. H., Vinberg, M., Kessing, L. V., & Coello, K. (2023) · Nutritional Neuroscience · doi:10.1080/1028415x.2023.2277970 · Cited by 32 · see citing works

Metabolic Profiling and Quantitative Analysis of Cerebrospinal Fluid Using Gas Chromatography–Mass Spectrometry: Current Methods and Future Perspectives

Pautova, A. K., Burnakova, N. A., & Revelsky, A. I. (2021) · Molecules · doi:10.3390/molecules26123597 · Cited by 26 · see citing works

The Relationship between Canine Behavioral Disorders and Gut Microbiome and Future Therapeutic Perspectives

Kiełbik, P., & Witkowska‐Piłaszewicz, O. (2024) · Animals · doi:10.3390/ani14142048 · Cited by 24 · see citing works

Microorganisms as Shapers of Human Civilization, from Pandemics to Even Our Genomes: Villains or Friends? A Historical Approach

Rodríguez‐Frias, F., Quer, J., Tabernero, D., Cortese, M. F., García-García, S., Rando‐Segura, A., & Pumarola, T. (2021) · Microorganisms · doi:10.3390/microorganisms9122518 · Cited by 23 · see citing works

Entorhinal cortex-based metabolic profiling of chronic restraint stress mice model of depression

Chen, X., Lan, T., Wang, Y., He, Y., Wu, Z., Tian, Y., Li, Y., Bai, M., Zhou, W., Zhang, H., et al. (2020) · Aging · doi:10.18632/aging.102798 · Cited by 19 · see citing works

Linking the Triad of Telomere Length, Inflammation, and Gut Dysbiosis in the Manifestation of Depression

Bazaz, M. R., Balasubramanian, R., Monroy‐Jaramillo, N., & Dandekar, M. P. (2021) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.1c00457 · Cited by 19 · see citing works

Disrupted gut harmony in attention-deficit/hyperactivity disorder: Dysbiosis and decreased short-chain fatty acids

Steckler, R., Magzal, F., Kokot, M., Walkowiak, J., & Tamir, S. (2024) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2024.100829 · Cited by 19 · see citing works

Multi-omics Analysis of the Amygdala in a Rat Chronic Unpredictable Mild Stress Model of Depression

Li, X., Zhou, X., Teng, T., Fan, L., Liu, X., Xiang, Y., Jiang, Y., Xie, P., & Zhu, D. (2021) · Neuroscience · doi:10.1016/j.neuroscience.2021.03.031 · Cited by 19 · see citing works

Critical Factors in Sample Collection and Preparation for Clinical Metabolomics of Underexplored Biological Specimens

de Souza, H. M. R., Pereira, T. T. P., de Sá, H. C., Alves, M. A., Garrett, R., & Canuto, G. A. B. (2024) · Metabolites · doi:10.3390/metabo14010036 · Cited by 18 · see citing works

Metabolomics in Depression: What We Learn from Preclinical and Clinical Evidences

Singh, P., Vasundhara, B., Das, N., Sharma, R., Kumar, A., & Datusalia, A. K. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04302-5 · Cited by 16 · see citing works

Disordered gut microbiota and changes in short-chain fatty acids and inflammatory processes in stress-vulnerable mice

Han, W., Zheng, Y., Wang, L., & An, C. (2023) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2023.578172 · Cited by 15 · see citing works

Promising new pharmacological targets for depression: The search for efficacy

Tsugiyama, L. E., de Moraes, R. C. M., Moraes, Y. A. C., & de Oliveira, J. F. (2023) · Drug Discovery Today · doi:10.1016/j.drudis.2023.103804 · Cited by 14 · see citing works

Plasma metabolomic profiles associated with chronic distress in women

Shutta, K. H., Balasubramanian, R., Huang, T., Jha, S. C., Zeleznik, O. A., Kroenke, C. H., Tinker, L. F., Smoller, J. W., Casanova, R., Tworoger, S. S., et al. (2021) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2021.105420 · Cited by 14 · see citing works

Breathomics profiling of metabolic pathways affected by major depression: Possibilities and limitations

Gbaoui, L., Fachet, M., Lüno, M., Meyer-Lotz, G., Frodl, T., & Hoeschen, C. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.1061326 · Cited by 12 · see citing works

Disorders in the gut and liver are involved in depression contagion between isosexual post-stroke depression mice and the healthy cohabitors

Wang, H., Wang, B., Pan, M.-B., Jiang, S.-T., Wang, Y.-C., Zhu, Y., Zhang, Q., & Dong, Y. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2022.114246 · Cited by 12 · see citing works

Combined metabolomics and transcriptomics analysis of rats under neuropathic pain and pain-related depression

Xi, C., He, L., Huang, Z., Zhang, J., Zou, K., Guo, Q., & Huang, C. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1320419 · Cited by 10 · see citing works

Gut microbiota connects the brain and the heart: potential mechanisms and clinical implications

Zhang, Y., Huang, K., Duan, J., Zhao, R., & Yang, L. (2024) · Psychopharmacology · doi:10.1007/s00213-024-06552-6 · Cited by 9 · see citing works

Thermal Stability of Fructooligosaccharides Extracted from Defatted Rice Bran: A Kinetic Study Using Liquid Chromatography-Tandem Mass Spectrometry

Le, H. P., Hong, D. T. N., Nguyen, T. T. L., Le, T. M. H., Koseki, S., Ho, B. T., & Nguyen, B. L. (2022) · Foods · doi:10.3390/foods11142054 · Cited by 7 · see citing works

Chronic exposure to metam sodium-based pesticide in mice during adulthood elevated anxiety and depression-like behaviors: Involvement of serotoninergic depletion and gut microbiota dysbiosis

Kaikai, N.-E., Ba-M’hamed, S., Slimani, A., Dilagui, I., Hanchi, A. L., Soraa, N., Mezrioui, N., Bennis, M., & Ghanima, A. (2023) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2023.104066 · Cited by 7 · see citing works

Gut–brain axis and depression: focus on the amino acid and short-chain fatty acid metabolism

Chen, M., Lyu, Q., Huang, L., Lou, Y., & Wang, L. (2025) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000851 · Cited by 6 · see citing works

Metabolomics and Microbiomics: New Potential Strategies in Chronic Pain Syndrome

Piras, C., Pintus, B. M., Noto, A., Evangelista, M., Fanos, V., Musu, M., Mussap, M., Atzori, L., Sardo, S., & Finco, G. (2022) · Journal of Pain Research · doi:10.2147/jpr.s354516 · Cited by 5 · see citing works

Differences in cognition, short-chain fatty acids and related metabolites in pregnant versus non-pregnant women: a cross-sectional study

Luo, H., Li, W., Wu, L., Zhong, S., Du, C., Liu, Y., Xu, Y., Huang, X., Bahru, A. H., Tang, X., et al. (2022) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-022-04853-2 · Cited by 5 · see citing works

Positioning berries in nutritional psychiatry: potential for prevention and co-therapy in mental health

Fernández-Demeneghi, R., Domínguez-Pantoja, M., Moreno, A. G. M., Vargas-Moreno, I., & Ramírez-Rodríguez, R. (2025) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2025.1622242 · Cited by 4 · see citing works

Stressor-Specific Microbiota Intervention

Chuang, J.-Y. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.870665 · Cited by 4 · see citing works

Untargeted Metabolite Profiling of Adipose Tissue in Rats Exposed to Mepiquat

Hu, C., Song, X., Shao, Z., Liu, Y., Wang, J., & Sun, B. (2023) · Foods · doi:10.3390/foods12040867 · Cited by 2 · see citing works

Milk fat globule membrane ameliorates depressive-like behaviors in chronic unpredictable mild stress rats by modulating the microbiota-gut-brain axis

Huang, L. Y., Zheng, Y., Liu, Q., Feng, Y., Ma, Z., Zhao, X., Xinru, W. E. I., Xinyue, Y. U., Xia, L. V., Lv, J., et al. (2025) · Bioscience of Microbiota Food and Health · doi:10.12938/bmfh.2025-031 · Cited by 1 · see citing works

Cognitive impairment in bipolar disorder associated with abnormal serum short-chain fatty acids and cytokines

Fan, Y., Zhao, B., Jia, M., Qi, Z., Gao, Y., Wen, B., Dong, Y., Wang, W., Feng, J., Ma, X., et al. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-07619-0 · Cited by 2 · see citing works

DepBoost-TransNet: Boosted Transformer Network for Depression Classification

Rahood, P. A., Kumaresan, P. K., & Chakravarthi, B. R. (2024) · Communications in computer and information science · doi:10.1007/978-3-031-58495-4_8 · Cited by 1 · see citing works

A review of nonhuman primate models of depressive disorder

Bao, Y., Luan, D., & Meng, Z. (2025) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2025.111421 · Cited by 1 · see citing works

The prebiotic effects of amadumbe (Colocasia Esculenta) and okra (Abelmoschus esculentus) mucilage

Gajadhar, S. (2023) · doi:10.51415/10321/4803 · Cited by 1 · see citing works

Behavioral and pharmacological validation of the differential reinforcement of low-rate behavior paradigm in non-human primates

Vanderlip, C. R., Dunn, S. R., Basile, J. L., Wettstein, J. G., Vivian, J. A., & Glavis‐Bloom, C. (2026) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000893

A cross-sectional study of the correlation between short-chain fatty acids, lipids, cytokines, and cognition, emotions in late pregnancy

Zhou, J., Li, W., Zhang, Y., Liu, J., Deng, X., Bin, X., Sun, Y., He, Z., Yang, J., Shen, J., et al. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.120432

Genetic and metabolic inflammation signatures in chronic inflammatory demyelinating polyneuropathy: the role of IL18 polymorphisms and short-chain fatty acids

Andrusiów, S., Dratwa, M., Łacina, P., Bochen, P., Gładysz, K., Szponar, B., Koszewicz, M. A., & Bogunia‐Kubik, K. (2026) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2025.1738817

Untargeted and Targeted Cerebrospinal Fluid Neurometabolomics via Chromatography–Mass Spectrometry-Based Methods

Pautova, A. K. (2026) · Molecules · doi:10.3390/molecules31111822

Microbiota and mycobiota in chronic inflammatory demyelinating polyneuropathy: clinical and pathophysiological correlations

Andrusiów, S., Brzoza, A., Łacina, P., Dratwa-Kuźmin, M., Raczkowska, J., Kujawa, D., Romańczuk, K., Gancarek, M., Bochen, P., Dziadkowiak, E., et al. (2026) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2026.1802462

Rifaximin Plus Probiotics Reshape Gut Microbiota, Serum Propionate, and Mucosal Immunity in Cirrhosis‐Related Hepatic Encephalopathy Microbiota‐Immune Remodeling in HE

Wang, Y., Zhu, H., Wang, S., Hu, D., Xu, M., Lee, L., & Lee, D. (2026) · Canadian Journal of Gastroenterology and Hepatology · doi:10.1155/cjgh/2389961

Gut Microbial-Related Alanine, Aspartate, and Glutamate Metabolism is Disordered in Peripheral and Central Tissues of Depressed Mice

Xie, J., Bai, S., He, F., Xu, K. X., Wang, J., Ren, Y., Chen, J., & Xie, P. (2026) · Current Neuropharmacology · doi:10.2174/011570159x429580260210055247

Amino acid metabolic dysfunction revealed in the prefrontal cortex of a rat model of depression

Chen, G., Yang, D., Yang, Y., Li, J., Cheng, K., Tang, G., Zhang, R., Zhou, J., Li, W., Liu, Z., et al. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.05.027 · Cited by 77 · see citing works

Biogeography of the large intestinal mucosal and luminal microbiome in cynomolgus macaques with depressive-like behavior

Teng, T., Clarke, G. A., Maes, M. H. J., Jiang, Y., Wang, J., Li, X., Yin, B., Xiang, Y., Fan, L., Liu, X., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01366-w · Cited by 55 · see citing works

Associations Between Disordered Microbial Metabolites and Changes of Neurotransmitters in Depressed Mice

Xie, J., Wang, Y., Zhong, Q., Bai, S., Zhou, C., Tian, T., & Chen, J. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.906303 · Cited by 33 · see citing works

Chronic mild stress leads to aberrant glucose energy metabolism in depressed Macaca fascicularis models

Qin, Y., Jiang, X., Li, W., Li, J., Tian, T., Zang, G., Fang, L., Zhou, C., Xu, B., Gong, X., et al. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.05.007 · Cited by 40 · see citing works