Emerging strategies in the treatment of poststroke depression and psychiatric distress in patients
Open accessAbstract
Poststroke depression (PSD) is a common sequela of stroke associated with increased morbidity and mortality among stroke survivors. PSD has been associated with poorer rehabilitative outcomes, longer inpatient stays, inefficient use of medical resources, worsened cognitive decline, and increased suicidality. This article reviews the definition and proposed etiology of PSD as well as current and emerging evidence-based prevention, screening, and treatment modalities. The timely use of prevention and treatment techniques including pharmacologic and nonpharmacologic methods may improve treatment outcomes and enhance the quality of life in stroke patients.
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Psychopharmacological interventions have mixed results when treating depression in stroke survivors, and stroke patients seem sensitive to side effects of psychopharmacological medication.
“Psychopharmacological interventions have mixed results when treating depression in stroke survivors. Additionally, stroke patients seem sensitive to the side effects of psychopharmacological medication [8].”
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- Authors
- Capaldi II, V. F., & Wynn
- Affiliations
- Walter Reed Army Institute of Research (US)
- Venue
- Psychology Research and Behavior Management
- Publisher
- Informa UK Limited
- Published
- 2010-12
- Volume
- 3
- Pages
- 109
- ISSN
- 1179-1578 (ISSN-L)
- PMC
- PMC3218762
- OpenAlex
- W2015033896
- Cited by
- 25
- References
- 120
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 4 · 2018: 2 · 2017: 3 · 2016: 1 · 2015: 1 · 2014: 3 · 2012: 2
- FWCI
- 0.67
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Psychology Research and Behavior Management (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
- Topics
- Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- post-stroke depression, stroke, psychiatric distress, etiology of depression, depression prevention, depression screening, pharmacotherapy, non-pharmacological treatment, stroke rehabilitation, suicidality, cognitive decline, quality of life
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