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Cited by 87Stroke Rehabilitation and RecoveryAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesCardiac Health and Mental Health

Clinical correlates of early-onset and late-onset poststroke generalized anxiety

CARLOS S. CASTILLO, Susan K. Schultz, Robert G. Robinson·1995·American Journal of Psychiatry
DOI 10.1176/ajp.152.8.1174
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Abstract

OBJECTIVE: The authors' goal was to determine if generalized anxiety diagnosed while a patient was hospitalized for stroke (early onset) had the same clinical correlates as anxiety beginning 3 months or more after the stroke (late onset). METHOD: Patients with acute stroke (N = 142) were examined while they were in the hospital and 3, 6, 12, and 24 months later for the presence of anxiety symptoms. Patients underwent a structured psychiatric interview as well as assessment of cognitive, physical, and social function at each visit. Patients with early-onset and late-onset poststroke generalized anxiety were identified and compared to patients without poststroke generalized anxiety. RESULTS: The frequency of early-onset poststroke generalized anxiety was 27% and that of late-onset poststroke generalized anxiety was 23%. Three-quarters of the anxious patients had comorbid major or minor depression. Patients who developed early-onset or late-onset poststroke generalized anxiety were no more socially, cognitively, or physically impaired than patients who did not develop anxiety. Early-onset but not late-onset anxiety was associated with a previous history of psychiatric disorder. The median duration of late-onset anxiety was 3.0 months, and that of early-onset anxiety was 1.5 months. The presence of anxiety was significantly associated with depression; onset of depression and onset of anxiety occurred at approximately the same time. CONCLUSIONS: These findings suggest that although early-onset and late-onset poststroke generalized anxiety are phenomenologically similar, they may be the result of different pathophysiological mechanisms.

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  • Among the approaches explored, CBT has been the subject of the most structured studies.

    “Parmi les différentes approches explorées, ce sont les thérapies cognitivo-comportementales qui ont fait l'objet des études les plus structurées.”

    From Prise en charge des troubles anxieux dans le cadre d'atteintes neurologiques (2004) · cites this paper as [14]

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Authors
CASTILLO, C. S., Schultz, S. K., & Robinson, R. G.
Affiliations
University of Iowa Hospitals and Clinics (US)
ORCID
Susan K. Schultz
Venue
American Journal of Psychiatry
Publisher
American Psychiatric Association Publishing
Published
1995-08-01
Volume
152
Issue
8
Pages
1174-1179
ISSN
  • 0002-953X (ISSN-L)
  • 1535-7228
DOI
10.1176/ajp.152.8.1174
OpenAlex
W2418858837
Cited by
87
References
14
Citations by year
2026: 2 · 2024: 2 · 2023: 3 · 2021: 7 · 2020: 5 · 2019: 5 · 2018: 2 · 2016: 1 · 2015: 2 · 2014: 3 · 2013: 7 · 2012: 1
FWCI
2.16
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal of Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5r01mh040355-06)
  • National Institute of Mental Health (MH 40355, MH 00163)
Topics
  • Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Keywords
stroke, comorbid depression, psychiatric comorbidity, cognitive function, social function, physical function
MeSH terms
Anxiety Disorders, Mental Disorders, Cerebrovascular Disorders, Depressive Disorder, Female, Follow-Up Studies, Hospitalization, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Comorbidity, Prevalence

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