Cited by 610Antifungal resistance and susceptibilityFungal Infections and StudiesYeasts and Rust Fungi Studies

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Epidemiology and risk factors for invasive candidiasis

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Yapar, Nur·2014·Therapeutics and Clinical Risk Management

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Abstract

The number of immunosuppressive patients has increased significantly in recent years. These patients are at risk for opportunistic infections, especially fungal infections. Candidiasis is one of the most frequent fungal infections determined in these immunosuppressive patients and its epidemiology has changed over the last two decades. Recently, new antifungal agents and new therapy strategies such as antifungal prophylaxis, secondary prophylaxis, and preemptive therapy have come into use. These changes resulted in the alteration of Candida species causing invasive infections. The incidence of Candida albicans was decreased in many countries, especially among patients with immunosuppressive disorders, while the incidence of species other than C. albicans was increased. In this review, incidence, risk factors, and species distribution of invasive candidiasis are discussed.

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Authors: Yapar, N.
Affiliations: Dokuz Eylül University (TR)
Corresponding author: Yapar, Nur
ORCID: Yapar, Nur
Venue: Therapeutics and Clinical Risk Management
Publisher: Informa UK Limited
Published: 2014-02
Volume: 10
Pages: 95
ISSN: 1176-6336 (ISSN-L)
1178-203X
DOI: 10.2147/tcrm.s40160
PMC: PMC3928396
OpenAlex: W2149946566
Cited by: 610
References: 70
Citations by year: 2026: 13 · 2025: 29 · 2024: 42 · 2023: 39 · 2022: 48 · 2021: 69 · 2020: 93 · 2019: 74 · 2018: 60 · 2017: 54 · 2016: 44 · 2015: 32 · 2014: 11
FWCI: 6.53
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by-nc
creativecommons.org/licenses/by-nc/3.0/ (vor)
Locations: Therapeutics and Clinical Risk Management (publishedVersion, cc-by-nc)
Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
PubMed Central (publishedVersion, cc-by-nc)
PubMed (publishedVersion)
Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
Topics: Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
Health Sciences › Medicine › Infectious Diseases › Fungal Infections and Studies
Life Sciences › Immunology and Microbiology › Microbiology › Yeasts and Rust Fungi Studies
Keywords: invasive candidiasis, Candida albicans, non-albicans Candida, immunosuppression, opportunistic fungal infection, risk factors, epidemiology, antifungal prophylaxis, secondary prophylaxis, preemptive antifungal therapy, species distribution

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Epidemiology and risk factors for invasive candidiasis

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