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Epidemiology and risk factors for invasive candidiasis
Open accessAbstract
The number of immunosuppressive patients has increased significantly in recent years. These patients are at risk for opportunistic infections, especially fungal infections. Candidiasis is one of the most frequent fungal infections determined in these immunosuppressive patients and its epidemiology has changed over the last two decades. Recently, new antifungal agents and new therapy strategies such as antifungal prophylaxis, secondary prophylaxis, and preemptive therapy have come into use. These changes resulted in the alteration of Candida species causing invasive infections. The incidence of Candida albicans was decreased in many countries, especially among patients with immunosuppressive disorders, while the incidence of species other than C. albicans was increased. In this review, incidence, risk factors, and species distribution of invasive candidiasis are discussed.
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“Its prevalence varies with the geographic area [2,3,4].”
From Candida glabrata: A Lot More Than Meets the Eye (2019) · cites this paper as [3]
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“Recent epidemiological surveys have shown a decrease in the frequency of C. albicans and an increased prevalence of non-albicans Candida [3,5,6].”
From Candida glabrata: A Lot More Than Meets the Eye (2019) · cites this paper as [3]
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Metadata
- Authors
- Yapar, N.
- Affiliations
- Dokuz Eylül University (TR)
- Corresponding author
- Yapar, Nur
- ORCID
- Yapar, Nur
- Venue
- Therapeutics and Clinical Risk Management
- Publisher
- Informa UK Limited
- Published
- 2014-02
- Volume
- 10
- Pages
- 95
- ISSN
- 1176-6336 (ISSN-L)
- 1178-203X
- PMC
- PMC3928396
- OpenAlex
- W2149946566
- Cited by
- 610
- References
- 70
- Citations by year
- 2026: 13 · 2025: 29 · 2024: 42 · 2023: 39 · 2022: 48 · 2021: 69 · 2020: 93 · 2019: 74 · 2018: 60 · 2017: 54 · 2016: 44 · 2015: 32 · 2014: 11
- FWCI
- 6.53
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Therapeutics and Clinical Risk Management (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Infectious Diseases › Fungal Infections and Studies
- Life Sciences › Immunology and Microbiology › Microbiology › Yeasts and Rust Fungi Studies
- Keywords
- invasive candidiasis, Candida albicans, non-albicans Candida, immunosuppression, opportunistic fungal infection, risk factors, epidemiology, antifungal prophylaxis, secondary prophylaxis, preemptive antifungal therapy, species distribution
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