Psycho-biological correlates of free-floating anxiety symptoms in male patients with sexual dysfunctions
Open accessAbstract
Anxiety has a relevant impact on everyday life, including sexual life, and therefore is considered the final common pathway by which social, psychological, and biological stressors negatively affect sexual functioning. The aim of this study is to define the psycho-biological correlates of free-floating anxiety in a large sample of patients complaining of erectile dysfunction (ED)-based sexual problems. We studied a consecutive series of 882 ED patients using SIEDY, a 13-item structured interview, composed of 3 scales that identify and quantify organic, relational, and intrapsychic domains. MHQ-A scoring from Middlesex Hospital Questionnaire (MHQ) was used as a putative marker of free-floating anxiety symptoms (AS). Metabolic and hormonal parameters, nocturnal penile tumescence (NPT) test, and penile Doppler ultrasound (PDU) examination were also performed. MHQ-A score was significantly higher in patients complaining of difficulties in maintaining erection and in those reporting premature ejaculation (6.5 +/- 3.3 vs 5.8 +/- 3.3 and 6.6 +/- 3.3 vs 6.1 +/- 3.3, respectively; both P < .05). Moreover, ASs were significantly correlated to life stressors quantified by SIEDY scale 2 (relational component) and scale 3 (intrapsychic component) scores, as dissatisfaction at work or within the family or couple relationships. Among physical, biochemical, or instrumental parameters tested, only end-diastolic velocity at PDU was significantly (P < .05) related to ASs. In conclusion, in patients with ED-based sexual problems, ASs are correlated to many relational and life stressors. Conversely, organic problems are not necessarily associated with MHQ-A score.
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Data from a large sample of patients seeking medical care for ED showed that free-floating anxiety has a relevant impact on maintaining the erection during intercourse, supporting a nonorganic origin of the problem.
“Accordingly, data performed in a large sample of patients seeking medical care for ED showed that free-floating anxiety has a relevant impact on maintaining the erection during intercourse which is another factor supporting a nonorganic origin of the problem.43”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [43]
Anxiety could be considered as the final common pathway by which social, psychological, and biological stressors disrupt sexual functioning.
“In particular, anxiety could be considered as the final common pathway by which social, psychological, and biological stressors disrupt sexual functioning.42,43”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [43]
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“42,43 Accordingly, data performed in a large sample of patients seeking medical care for ED showed that free-fl oating anxiety has a relevant impact on maintaining the erection during intercourse which is another factor supporting a nonorganic origin of the problem.”
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- Authors
- Corona, G., Mannucci, E., Petrone, L., Ricca, V., Balercia, G., Giommi, R., Forti, G., & Maggi, M.
- Affiliations
- Ospedale Bellaria (IT)
- University of Florence (IT)
- Marche Polytechnic University (IT)
- Corresponding author
- Maggi, Mario
- Venue
- Journal of Andrology
- Publisher
- Wiley
- Published
- 2006-01-02
- Volume
- 27
- Issue
- 1
- Pages
- 86-93
- ISSN
- 0196-3635 (ISSN-L)
- 1939-4640
- OpenAlex
- W2015871844
- Cited by
- 103
- References
- 37
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 5 · 2019: 3 · 2018: 5 · 2017: 3 · 2016: 5 · 2015: 9 · 2014: 6 · 2013: 16 · 2012: 6
- FWCI
- 3.61
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Andrology (publishedVersion)
- PubMed (publishedVersion)
- Florence Research (University of Florence) (submittedVersion)
- 8th European Congress of Endocrinology incorporating the British Endocrine Societies
- Funders
- Università degli Studi di Firenze
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
- Keywords
- free-floating anxiety, erectile dysfunction, sexual dysfunction, Middlesex Hospital Questionnaire, life events, relationship stress, premature ejaculation, nocturnal penile tumescence, penile Doppler ultrasound, end-diastolic velocity
- MeSH terms
- Adult, Aged, Anxiety, Humans, Erectile Dysfunction, Life Change Events, Male, Middle Aged, Surveys and Questionnaires, Stress, Psychological
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