SIEDY scale 3, a new instrument to detect psychological component in subjects with erectile dysfunction
Abstract
INTRODUCTION: We previously developed and validated a structured interview (SIEDY) dealing with the organic (Scale 1), relational (Scale 2), and psychological (Scale 3) components of erectile dysfunction (ED). AIM: To identify a pathological threshold for SIEDY Scale 3 and to analyze Scale 3 score with biological and psychological correlates in subjects with sexual dysfunction. METHOD: A pathological threshold of SIEDY Scale 3 score in predicting subjects with a medical history of psychopathology and using psychiatric drugs was identified through receiver operating characteristic (ROC) curve analysis in a sample of 484 patients (Sample A). MAIN OUTCOME MEASURE: Sensitivity and specificity, along with possible interactions with biological and psychological (Middlesex Hospital Questionnaire, MHQ-score) correlates were verified in a further sample of 1,275 patients (Sample B). RESULTS: In sample A, 39 (8%) and 60 (12.4%) subjects reported a positive medical history for psychiatric disturbances or for the use of psychotropic medication, respectively. The association with both conditions was present in 28 (5.8%) subjects. ROC curve showed that SIEDY Scale 3 score predicts psychopathology with an accuracy of 69.5 ± 5.9% (P<0.002), when a threshold of 3 was chosen. When the same threshold was applied in Sample B, it identified a higher ranking in MHQ-A (free-floating anxiety), MHQ-S (somatized anxiety) and MHQ-D (depressive symptoms) subscales, even after adjustment for age and Σ-MHQ (a broader index of general psychopathology). In the same sample, we also confirmed that pathological Scale 3 score was related to a higher risk of psychopathology at medical history or to the use of psychotropic drugs as well as with risky lifestyle behaviors, including smoking and alcohol abuse, and elevated BMI. CONCLUSIONS: SIEDY represents an easy tool for the identification of patients with a relevant intra-psychic component who should be considered for psychological/psychiatric treatment.
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Erectile function involves a dynamic interplay between vascular, neurologic, hormonal, psychological and relational/social factors.
“erectile function involves a dynamic interplay between vascular, neurologic, hormonal as well as psychological and relational/social factors.4,5”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [5]
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Zhang, Y.-X., Zhang, X.-Q., Wang, Q.-R., Yuan, Y.-Q., Yang, J.-G., Zhang, X.-W., & Li, Q. (2016) · Reproductive Health · doi:10.1186/s12978-016-0188-y · Cited by 30 · see citing works
Corona, G., Cipriani, S., Rastrelli, G., Sforza, A., Mannucci, E., & Maggi, M. (2016) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2016.07.004 · Cited by 29 · see citing works
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Self-citationCorona, G., Rastrelli, G., Silverii, G. A., Monami, M., Sforza, A., Forti, G., Mannucci, E., & Maggi, M. (2013) · The Journal of Sexual Medicine · doi:10.1111/jsm.12066 · Cited by 27 · see citing works
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Molina‐Leyva, A., Almódovar-Real, A., Ruiz‐Carrascosa, J. C., Naranjo‐Sintes, R., Serrano‐Ortega, S., & Jiménez‐Moleón, J. J. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12710 · Cited by 26 · see citing works
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Rastrelli, G., Corona, G., Fisher, A. D., Silverii, G. A., Mannucci, E., & Maggi, M. (2012) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2012.02947.x · Cited by 21 · see citing works
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Is marijuana a foe of male sexuality? Data from a large cohort of men with sexual dysfunction
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Acquired hypoprolactinemia in men, possible phenotype
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Testosterone and Sexual Function
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- Authors
- Corona, G., Ricca, V., Bandini, E., Rastrelli, G., Casale, H., Jannini, E. A., Sforza, A., Forti, G., Mannucci, E., & Maggi, M.
- Affiliations
- Azienda USL di Bologna (IT)
- University of Florence (IT)
- University of L'Aquila (IT)
- Corresponding author
- Maggi, Mario
- ORCID
- Venue
- The Journal of Sexual Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-08
- Volume
- 9
- Issue
- 8
- Pages
- 2017-2026
- ISSN
- 1743-6095 (ISSN-L)
- OpenAlex
- W1653327953
- Cited by
- 89
- References
- 55
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 6 · 2023: 7 · 2022: 5 · 2021: 1 · 2020: 2 · 2019: 3 · 2018: 3 · 2017: 9 · 2016: 10 · 2015: 10 · 2014: 11 · 2013: 11 · 2012: 4
- FWCI
- 8.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Sexual Medicine (publishedVersion)
- PubMed (publishedVersion)
- Cineca Institutional Research Information System (Tor Vergata University) (submittedVersion)
- Florence Research (University of Florence) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Urology › Urological Disorders and Treatments
- Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
- Keywords
- erectile dysfunction, psychopathology, psychotropic drugs, anxiety, depressive symptoms, Middlesex Hospital Questionnaire, screening tool, lifestyle risk factors, body mass index
- MeSH terms
- Adult, Anxiety, Mental Disorders, Depression, Female, Humans, Erectile Dysfunction, Life Style, Male, Middle Aged, Psychological Tests, Surveys and Questionnaires, Sensitivity and Specificity
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