Cited by 48Antifungal resistance and susceptibilityInfective Endocarditis Diagnosis and ManagementCentral Venous Catheters and Hemodialysis

Candidaemia in Patients with an Inserted Medical Device

Cauda, Roberto·2009·Drugs

Abstract

The importance of medical devices as a source of infection has been increasingly appreciated. Candida spp. are responsible for a significantly increasing number of device-related infections, particularly those involving the bloodstream and urinary tract. A wide range of devices may be colonized by Candida spp., including central venous catheters, cardiac devices, and knee and hip prostheses. Medical device infections invariably require antifungal therapy and, in many cases, device removal, with associated hazards to some patients. Currently recommended treatments include amphotericin B formulations, azoles and echinocandins. The echinocandins, with efficacy against Candida biofilms, may have a role in the future in improved lock therapy for the treatment of device-associated candidal infections.

Integrity signals

Registry

Crossref · 10.2165/11315520-000000000-00000

Cites

21 of 21 references verified0 citation errors · 0 not checkable

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  • Urinary and central venous catheters, pacemakers, mechanical heart valves, joint prostheses, contact lenses, and dentures are all susceptible to C. albicans biofilms.

    “Urinary and central venous catheters, pacemakers, mechanical heart valves, joint prostheses, contact lenses, and dentures are all susceptible to C. albicans biofilms (22, 45, 90, 175).”

    From <i>Candida albicans</i> Biofilms and Human Disease (2015) · cites this paper as [22]

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Authors
Cauda, R.
Affiliations
Università Cattolica del Sacro Cuore (IT)
Corresponding author
Cauda, Roberto
Venue
Drugs
Published
2009-11
Volume
69
Issue
Supplement 1
Pages
33-38
ISSN
0012-6667 (ISSN-L)
OpenAlex
W2066615848
Cited by
48
References
21
Citations by year
2023: 2 · 2022: 3 · 2021: 2 · 2020: 4 · 2019: 3 · 2018: 1 · 2017: 4 · 2016: 2 · 2015: 7 · 2014: 3 · 2013: 7 · 2012: 2
FWCI
2.29
Type
journal article
Language
en
Open access
closed
Locations
  • Drugs (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Pfizer
  • Infectious Diseases Society of America
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Health Sciences › Medicine › Epidemiology › Infective Endocarditis Diagnosis and Management
  • Health Sciences › Health Professions › Emergency Medical Services › Central Venous Catheters and Hemodialysis
Keywords
candidemia, Candida, medical device-related infections, central venous catheters, cardiac devices, periprosthetic joint infection, antifungal therapy, echinocandins, amphotericin B, azoles, Candida biofilms, catheter lock therapy, device removal
MeSH terms
Antifungal Agents, Candidiasis, Catheterization, Central Venous, Equipment and Supplies, Humans, Urinary Tract Infections, Fungemia, Prostheses and Implants

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