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Cited by 256

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Geographic Differences in Gastric Cancer Incidence Can be Explained by Differences between Helicobacter pylori Strains

Open access
Yamaoka, Yoshio, Kato, Mototsugu, Asaka, Masahiro·2008·Internal Medicine

Abstract

Certain populations with high incidences of Helicobacter pylori infection, such as those in East Asian countries, have high incidences of gastric cancer, while other highly infected populations, such as those in Africa and South Asia, do not. The various rates of gastric cancer associated with different geographic areas can be explained, at least in part, by the differences in the genotypes of H. pylori cagA and vacA. Populations expressing a high incidence of gastric cancer are mostly identical with regions where East Asian type CagA is predominant. In contrast, incidence of gastric cancer is low in Africa, South Asia, and Europe, where strains typically possess Western type CagA. Within East Asia, strains from northern parts, where the incidence of gastric cancer is high, predominantly possess the vacA m1 genotype, whereas the m2 genotype is predominant in southern parts where the gastric cancer incidence is low.

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Crossref · 10.2169/internalmedicine.47.0975

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Metadata

Authors
Yamaoka, Y., Kato, M., & Asaka, M.
Venue
Internal Medicine
Published
2008
Volume
47
Issue
12
Pages
1077-1083
ISSN
  • 0918-2918 (ISSN-L)
  • 1349-7235
OpenAlex
W1985005432
Cited by
256
References
1
FWCI
17.45
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Geographic Differences in Gastric Cancer Incidence Can be Explained by Differences between Helicobacter pylori Strains. https://app.cochat.ai/papers/10.2169/internalmedicine.47.0975
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Yamaoka, Y., Kato, M., & Asaka, M. (2008). Geographic Differences in Gastric Cancer Incidence Can be Explained by Differences between Helicobacter pylori Strains. Internal Medicine. https://doi.org/10.2169/internalmedicine.47.0975

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.