Research Mechanism and Progress of the Natural Compound Curcumin in Treating Alzheimer’s Disease

The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics

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Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

Selenica, M.-L. B., Brownlow, M., Jimenez, J. P., Lee, D. C., Pena, G., Dickey, C. A., Gordon, M. N., & Morgan, D. (2013) · Neurodegenerative Diseases · doi:10.1159/000337230 · Cited by 10,359 · see citing works

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide

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A clearer vision for in vivo imaging

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Acetylcholinesterase Inhibitors: Pharmacology and Toxicology

Colovic, M. B., Krstic, D. Z., Lazarevic-Pasti, T. D., Bondzic, A. M., & Vasic, V. M. (2013) · Current Neuropharmacology · doi:10.2174/1570159x11311030006 · Cited by 2,611 · see citing works

Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo

Yang, F., Lim, G. P., Begum, A. N., Ubeda, O. J., Simmons, M. R., Ambegaokar, S. S., Chen, P. P., Kayed, R., Glabe, C. G., Frautschy, S. A., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m404751200 · Cited by 2,336 · see citing works

Curcumin as “Curecumin”: From kitchen to clinic

Goel, A., Kunnumakkara, A. B., & Aggarwal, B. B. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.08.016 · Cited by 2,237 · see citing works

Curcumin: the Indian solid gold.

Aggarwal, B., Sundaram, C., Malani, N., & Ichikawa, H. (2007) · Advances in Experimental Medicine and Biology · doi:10.1007/978-0-387-46401-5_1 · Cited by 1,742 · see citing works

Curcumin: The story so far

Sharma, R. A., Gescher, A. J., & Steward, W. P. (2005) · European Journal of Cancer · doi:10.1016/j.ejca.2005.05.009 · Cited by 1,701 · see citing works

Dose escalation of a curcuminoid formulation

Lao, C. D., Ruffin, M. T., Normolle, D. P., Heath, D. D., Murray, S. I., Bailey, J. M., Boggs, M. E., Crowell, J. A., Rock, C. L., & Brenner, D. E. (2006) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-6-10 · Cited by 1,400 · see citing works

Curcumin, an active component of turmeric ( Curcuma longa ), and its effects on health

Bozkurt, B. K., & Şanlıer, N. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2015.1077195 · Cited by 1,251 · see citing works

Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases

Tan, B. L., Norhaizan, M. E., Liew, W.-P.-P., & Rahman, H. S. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01162 · Cited by 1,221 · see citing works

Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.

Masters, C. L., Multhaup, G., Simms, G., Pottgiesser, J., Martins, R. N., & Beyreuther, K. T. (1985) · The EMBO Journal · doi:10.1002/j.1460-2075.1985.tb04000.x · Cited by 1,043 · see citing works

Roles of tau protein in health and disease

Guo, T., Noble, W., & Hanger, D. P. (2017) · Acta Neuropathologica · doi:10.1007/s00401-017-1707-9 · Cited by 1,003 · see citing works

Linking lipids to Alzheimer's disease: cholesterol and beyond

Di Paolo, G., & Kim, T.-W. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3012 · Cited by 972 · see citing works

Alzheimer's disease: the cholesterol connection

Puglielli, L., Tanzi, R. E., & Kovacs, D. M. (2003) · Nature Neuroscience · doi:10.1038/nn0403-345 · Cited by 864 · see citing works

Structures of filaments from Pick’s disease reveal a novel tau protein fold

Falcon, B., Zhang, W., Murzin, A. G., Murshudov, G. N., Garringer, H. J., Vidal, R., Crowther, R. A., Ghetti, B. F., Scheres, S. H. W., & Goedert, M. (2018) · Nature · doi:10.1038/s41586-018-0454-y · Cited by 837 · see citing works

Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment

Basnet, P., & Škalko‐Basnet, N. (2011) · Molecules · doi:10.3390/molecules16064567 · Cited by 737 · see citing works

The Targets of Curcumin

Zhou, H., Beevers, C. S., & Huang, S. (2011) · Current Drug Targets · doi:10.2174/138945011794815356 · Cited by 715 · see citing works

Curcumin labels amyloid pathology in vivo , disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model

Garcı́a-Alloza, M., Borrelli, L. A., Rozkalne, A., Hyman, B. T., & Bacskai, B. J. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04613.x · Cited by 663 · see citing works

Peptide Fibrillization

Hamley, I. W. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200700861 · Cited by 619 · see citing works

Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer’s Disease

Begum, A. N., Jones, M. R., Lim, G. P., Morihara, T., Kim, P., Heath, D. D., Rock, C. L., Pruitt, M. A., Yang, F., Hudspeth, B., et al. (2008) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.108.137455 · Cited by 604 · see citing works

Curcumin and its nano-formulation: The kinetics of tissue distribution and blood–brain barrier penetration

Tsai, Y.-M., Chien, C.-F., Lin, L.-C., & Tsai, T. (2011) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2011.06.030 · Cited by 535 · see citing works

Mitochondria-targeted antioxidants protect against amyloid-β toxicity in Alzheimer's disease neurons

Manczak, M., Mao, P., Calkins, M. J., Cornea, A., Reddy, A. P., Murphy, M. P., Szeto, H. H., Park, B., & Reddy, P. H. (2010) · Journal of Alzheimer's Disease · doi:10.3233/jad-2010-100564 · Cited by 469 · see citing works

REVIEW: Curcumin and Alzheimer’s disease

Hamaguchi, T., Ono, K., & Yamada, M. (2010) · CNS Neuroscience & Therapeutics · doi:10.1111/j.1755-5949.2010.00147.x · Cited by 450 · see citing works

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

Ferreira, S. T., & Klein, W. L. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.08.003 · Cited by 442 · see citing works

Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats

Thiyagarajan, M., & Sharma, S. S. (2003) · Life Sciences · doi:10.1016/j.lfs.2003.06.042 · Cited by 418 · see citing works

TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys

Lourenco, M. V., Clarke, J. R., Frozza, R. L., Bomfim, T. R., Forny‐Germano, L., Batista, A. F., Sathler, L. B., Brito‐Moreira, J., Amaral, O. B., Silva, C. A., et al. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.11.002 · Cited by 415 · see citing works

Reactive oxygen species - sources, functions, oxidative damage.

Jakubczyk, K., Dec, K., Kałduńska, J., Kawczuga, D., Kochman, J., & Janda, K. (2020) · PubMed · Cited by 409 · see citing works

Nucleus basalis of Meynert revisited: anatomy, history and differential involvement in Alzheimer’s and Parkinson’s disease

Liu, A. K. L., Chang, R. C., Pearce, R. K. B., & Gentleman, S. (2015) · Acta Neuropathologica · doi:10.1007/s00401-015-1392-5 · Cited by 365 · see citing works

Design and Synthesis of Curcumin Analogues for in Vivo Fluorescence Imaging and Inhibiting Copper-Induced Cross-Linking of Amyloid Beta Species in Alzheimer’s Disease

Zhang, X., Tian, Y., Zeng, L., Tian, X., Sun, H., Liu, H., Moore, A. V., & Ran, C. (2013) · Journal of the American Chemical Society · doi:10.1021/ja405239v · Cited by 352 · see citing works

Curcumin and its analogues: Potential anticancer agents

Agrawal, D. K., & Mishra, P. K. (2009) · Medicinal Research Reviews · doi:10.1002/med.20188 · Cited by 311 · see citing works

Polymorphism in Alzheimer Aβ Amyloid Organization Reflects Conformational Selection in a Rugged Energy Landscape

Miller, Y., Ma, B., & Nussinov, R. (2010) · Chemical Reviews · doi:10.1021/cr900377t · Cited by 284 · see citing works

Accumulated Amyloid-β Peptide and Hyperphosphorylated Tau Protein: Relationship and Links in Alzheimer's Disease

Huang, H.-C., & Jiang, Z.-F. (2009) · Journal of Alzheimer's Disease · doi:10.3233/jad-2009-0960 · Cited by 278 · see citing works

Curcumin-loaded PLGA-PEG nanoparticles conjugated with B6 peptide for potential use in Alzheimer’s disease

Fan, S., Zheng, Y., Liu, X., Fang, W., Chen, X., Liao, W., Jing, X., Lei, M., Tao, E., Ma, Q., et al. (2018) · Drug Delivery · doi:10.1080/10717544.2018.1461955 · Cited by 263 · see citing works

Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer’s disease

Goozee, K. G., Shah, T. M., Sohrabi, H. R., Rainey‐Smith, S. R., Brown, B. M., Verdile, G., & Martins, R. N. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114515004687 · Cited by 245 · see citing works

Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood–brain barrier damage

Jiang, J., Wang, W., Sun, Y. J., Hu, M. Y., Li, F., & Zhu, D. Y. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.12.028 · Cited by 222 · see citing works

PROTECTIVE EFFECTS OF CURCUMIN AGAINST ISCHAEMIA/REPERFUSION INSULT IN RAT FOREBRAIN

Ghoneim, A. I., Abdel‐Naim, A. B., Khalifa, A. E., & El-Denshary, E.-E. S. M. (2002) · Pharmacological Research · doi:10.1016/s1043-6618(02)00123-8 · Cited by 197 · see citing works

A Visible and Near-Infrared, Dual-Channel Fluorescence-On Probe for Selectively Tracking Mitochondrial Glutathione

Xu, Z., Huang, X., Han, X., Wu, D., Zhang, B., Tan, Y. C., Cao, M., Liu, S. H., Yin, J., & Yoon, J. (2018) · Chem · doi:10.1016/j.chempr.2018.04.003 · Cited by 195 · see citing works

Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis

Wood, W. G., Li, L., Müller, W. E., & Eckert, G. P. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12637 · Cited by 194 · see citing works

Curcumin Decreases Amyloid-β Peptide Levels by Attenuating the Maturation of Amyloid-β Precursor Protein

Zhang, C. M., Browne, A., Child, D. D., & Tanzi, R. E. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.133520 · Cited by 190 · see citing works

The effects of curcumin supplementation on high‐sensitivity C‐reactive protein, serum adiponectin, and lipid profile in patients with type 2 diabetes: A randomized, double‐blind, placebo‐controlled trial

Adibian, M., Hodaei, H., Nikpayam, O., Sohrab, G., Hekmatdoost, A., & Hedayati, M. (2019) · Phytotherapy Research · doi:10.1002/ptr.6328 · Cited by 186 · see citing works

Curcumin Attenuates Amyloid-β Aggregate Toxicity and Modulates Amyloid-β Aggregation Pathway

Thapa, A., Jett, S. D., & Chi, E. Y. (2015) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5b00214 · Cited by 185 · see citing works

Accelerated cortical atrophy in cognitively normal elderly with high β-amyloid deposition

Chételat, G., Villemagne, V. L., Villain, N., Jones, G. R., Ellis, K. A., Ames, D. J., Martins, R. N., Masters, C. L., & Rowe, C. C. (2012) · Neurology · doi:10.1212/wnl.0b013e318246d67a · Cited by 176 · see citing works

The Cochaperone BAG2 Sweeps Paired Helical Filament- Insoluble Tau from the Microtubule

Carrettiero, D. C., Hernández, I., Neveu, P. A., Papagiannakopoulos, T. Y., & Kosik, K. S. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4660-08.2009 · Cited by 175 · see citing works

Synthesis and inhibition profiles of N-benzyl- and N-allyl aniline derivatives against carbonic anhydrase and acetylcholinesterase – A molecular docking study

Mahmudov, I., Demir, Y., Sert, Y., Abdullayev, Y., Sujayev, A. R., Alwasel, S. H., & Gülçın, İ. (2021) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2021.103645 · Cited by 153 · see citing works

Oxalate-curcumin–based probe for micro- and macroimaging of reactive oxygen species in Alzheimer’s disease

Yang, J., Zhang, X., Yuan, P., Yang, J., Xu, Y., Grutzendler, J., Shao, Y., Moore, A. V., & Ran, C. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1706248114 · Cited by 133 · see citing works

Radioligand Development for PET Imaging of β-Amyloid (Aβ)-Current Status

Cai, L., Innis, R. B., & Pike, V. W. (2006) · Current Medicinal Chemistry · doi:10.2174/092986707779313471 · Cited by 128 · see citing works

Curcumin inhibits IL1 alpha and TNF-alpha induction of AP-1 and NF-kB DNA-binding activity in bone marrow stromal cells.

Xu, Y. X., Pindolia, K. R., Janakiraman, N., Chapman, R. A., & Gautam, S. C. (1997) · PubMed · Cited by 123 · see citing works

Dietary Supplementation with Curcumin Reduce Circulating Levels of Glycogen Synthase Kinase-3β and Islet Amyloid Polypeptide in Adults with High Risk of Type 2 Diabetes and Alzheimer’s Disease

Thota, R. N., Rosato, J. I., Dias, C. B., Burrows, T. L., Martins, R. N., & Garg, M. L. (2020) · Nutrients · doi:10.3390/nu12041032 · Cited by 116 · see citing works

Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines

Gul, H. I., Mete, E., Taslımı, P., Gülçın, İ., & Supuran, C. T. (2016) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.1080/14756366.2016.1244533 · Cited by 109 · see citing works

Design, synthesis, biological evaluation and molecular docking studies of novel 1H-1,2,3-Triazole derivatives as potent inhibitors of carbonic anhydrase, acetylcholinesterase and aldose reductase

Anıl, D. A., Aydin, B. O., Demir, Y., & Türkmenoğlu, B. (2022) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2022.132613 · Cited by 90 · see citing works

Presence of an acidic glycoprotein in the serum of arthritic rats: Modulation by capsaicin and curcumin

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Microglial HO‐1 induction by curcumin provides antioxidant, antineuroinflammatory, and glioprotective effects

Parada, E., Buendía, I., Navarro, E., Avendaño, C., Egea, J., & López, M. G. (2015) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201500279 · Cited by 86 · see citing works

The Role of Wnt Signaling in the Development of Alzheimer’s Disease: A Potential Therapeutic Target?

Wan, W., Xia, S., Kalionis, B., Liu, L., & Li, Y. (2014) · BioMed Research International · doi:10.1155/2014/301575 · Cited by 86 · see citing works

Capping of Aβ42 Oligomers by Small Molecule Inhibitors

Fu, Z., Aucoin, D., Ahmed, M., Ziliox, M., Nostrand, W. E. V., & Smith, S. O. (2014) · Biochemistry · doi:10.1021/bi500910b · Cited by 85 · see citing works

Further Evidence of Benefits to Mood and Working Memory from Lipidated Curcumin in Healthy Older People: A 12-Week, Double-Blind, Placebo-Controlled, Partial Replication Study

Cox, K., White, D., Pipingas, A., Poorun, K., & Scholey, A. B. (2020) · Nutrients · doi:10.3390/nu12061678 · Cited by 81 · see citing works

Transition‐Metal Complexes of Bidentate Schiff‐Base Ligands: In Vitro and In Silico Evaluation as Non‐Classical Carbonic Anhydrase and Potential Acetylcholinesterase Inhibitors

Yaşar, Ü., Gönül, İ., Türkeş, C., Demir, Y., & Beydemir, Ş. (2021) · ChemistrySelect · doi:10.1002/slct.202102082 · Cited by 81 · see citing works

CSF tau protein andβ‐amyloid (1–42) in Alzheimer's disease diagnosis: discrimination from normal ageing and other dementias in the Greek population

Kapaki, E., Paraskevas, G. P., Zalonis, I., & Zournas, C. (2003) · European Journal of Neurology · doi:10.1046/j.1468-1331.2003.00562.x · Cited by 76 · see citing works

A study of the tautomerism of β-dicarbonyl compounds with special emphasis on curcuminoids

Cornago, P., Claramunt, R. M., Bouissane, L., Alkorta, I., & Elguero, J. (2008) · Tetrahedron · doi:10.1016/j.tet.2008.06.065 · Cited by 76 · see citing works

Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease

Popp, J., Lewczuk, P., Kölsch, H., Meichsner, S., Maier, W., Kornhuber, J., Jessen, F., & Lütjohann, D. (2012) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2012.07893.x · Cited by 75 · see citing works

Synthesis and in vitro carbonic anhydrases and acetylcholinesterase inhibitory activities of novel imidazolinone‐based benzenesulfonamides

Tugrak, M., Gul, H. I., Demir, Y., Levent, S., & Gülçın, İ. (2020) · Archiv der Pharmazie · doi:10.1002/ardp.202000375 · Cited by 74 · see citing works

Curcumin Ameliorates the Permeability of the Blood–Brain Barrier During Hypoxia by Upregulating Heme Oxygenase-1 Expression in Brain Microvascular Endothelial Cells

Wang, Y., Gu, Y.-T., Qin, G.-H., Zhong, L., & Meng, Y.-N. (2013) · Journal of Molecular Neuroscience · doi:10.1007/s12031-013-9989-4 · Cited by 71 · see citing works

Binding of Curcumin to Senile Plaques and Cerebral Amyloid Angiopathy in the Aged Brain of Various Animals and to Neurofibrillary Tangles in Alzheimer's Brain

Mutsuga, M., CHAMBERS, J. K., Uchida, K., Tei, M., MAKIBUCHI, T., 溝呂木達也, Takashima, A., & Nakayama, H. (2011) · Journal of Veterinary Medical Science · doi:10.1292/jvms.11-0307 · Cited by 71 · see citing works

Supplementation of curcumin and vitamin E enhances oxidative stress, but restores hepatic histoarchitecture in hypothyroid rats

Subudhi, U., Das, K., Paital, B., Bhanja, S., & Chainy, G. B. N. (2009) · Life Sciences · doi:10.1016/j.lfs.2008.12.024 · Cited by 70 · see citing works

Downstream modulation of extrinsic apoptotic pathway in streptozotocin-induced Alzheimer's dementia in rats: Erythropoietin versus curcumin

Samy, D. M., Ismail, C. A., Nassra, R. A., Zeitoun, T. M., & Nomair, A. M. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.11.046 · Cited by 70 · see citing works

Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons

Patil, S. P., Tran, N. T., Geekiyanage, H., Liu, L., & Chan, C. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.09.008 · Cited by 68 · see citing works

The Neuronal Tau Protein Blocks in Vitro Fibrillation of the Amyloid-β (Aβ) Peptide at the Oligomeric Stage

Wallin, C., Hiruma, Y., Wärmländer, S. K. T. S., Huvent, I., Jarvet, J., Abrahams, J. P., Gräslund, A., Lippens, G. M., & Luo, J. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.7b13623 · Cited by 67 · see citing works

Curcumin Alters the Salt Bridge-containing Turn Region in Amyloid β(1–42) Aggregates

Mithu, V. S., Sarkar, B., Bhowmik, D., Das, A. K., Chandrakesan, M., Maiti, S., & Madhu, P. K. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.519447 · Cited by 66 · see citing works

Curcumin Labeling of Neuronal Fibrillar Tau Inclusions in Human Brain Samples

Mohorko, N., Repovš, G., Popović, M., Kovács, G. G., & Bresjanac, M. (2010) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e3181d709eb · Cited by 60 · see citing works

Membrane-Mediated Neuroprotection by Curcumin from Amyloid-β-Peptide-Induced Toxicity

Thapa, A., Vernon, B. C., la Peña, K. D., Soliz, G., Moreno, H. A., López, G. P., & Chi, E. Y. (2013) · Langmuir · doi:10.1021/la4020459 · Cited by 60 · see citing works

A curcumin-based molecular probe for near-infrared fluorescence imaging of tau fibrils in Alzheimer's disease

Park, K., Seo, Y., Kim, M. K., Kim, K., Kim, Y. K., Choo, H., & Chong, Y. (2015) · Organic & Biomolecular Chemistry · doi:10.1039/c5ob01847a · Cited by 56 · see citing works

A colorimetric and fluorescent chemodosimeter for discriminative and simultaneous quantification of cysteine and homocysteine

Wang, L., Zhou, Q., Zhu, B., Yan, L., Ma, Z., Du, B., & Zhang, X. (2012) · Dyes and Pigments · doi:10.1016/j.dyepig.2012.05.006 · Cited by 56 · see citing works

Radioiodinated benzimidazole derivatives as single photon emission computed tomography probes for imaging of β-amyloid plaques in Alzheimer's disease

Cui, M., Ono, M., Kimura, H., Kawashima, H., Liu, B. L., & Saji, H. (2010) · Nuclear Medicine and Biology · doi:10.1016/j.nucmedbio.2010.09.012 · Cited by 56 · see citing works

Synthesis, optical properties and biological imaging of the rare earth complexes with curcumin and pyridine

Zhou, S., Xue, X., Wang, J., Dong, Y., Jiang, B., Don, W., Mao-lin, W., & Jia, Y. F. (2012) · Journal of Materials Chemistry · doi:10.1039/c2jm34117d · Cited by 55 · see citing works

Probing ion channel activity of human islet amyloid polypeptide (amylin)

Zhao, J., Luo, Y., Jang, H., Yu, X., Wei, G., Nussinov, R., & Zheng, J. (2012) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2012.08.012 · Cited by 55 · see citing works

The Natural Product Curcumin as a Potential Coadjuvant in Alzheimer's Treatment

Morales, I., Cerda-Troncoso, C., Andrade, V., & Maccioni, R. B. (2017) · Journal of Alzheimer s Disease · doi:10.3233/jad-170354 · Cited by 51 · see citing works

Curcumin improves tau-induced neuronal dysfunction of nematodes.

Miyasaka, T., Xie, C., Yoshimura, S., Shinzaki, Y., Yoshina, S., Kage-Nakadai, E., Mitani, S., & Ihara, Y. (2016) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2015.11.004 · Cited by 46 · see citing works

An insight into the in vivo imaging potential of curcumin analogues as fluorescence probes

Liu, Y., Zhang, C., Pan, H., Li, L., Yu, Y., & Liu, B. (2020) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2020.11.003 · Cited by 46 · see citing works

Application of curcumin nanoformulations in Alzheimer’s disease: prevention, diagnosis and treatment

Lv, H., Wang, Y., Yang, X., Ling, G., & Zhang, P. (2022) · Nutritional Neuroscience · doi:10.1080/1028415x.2022.2084550 · Cited by 41 · see citing works

A curcumin-based NIR fluorescence probe for detection of amyloid-beta (Aβ) plaques in Alzheimer's disease

Si, G., Zhou, S., Xu, G., Wang, J., Wu, B., & Zhou, S. (2018) · Dyes and Pigments · doi:10.1016/j.dyepig.2018.12.003 · Cited by 36 · see citing works

Drug Induced Liver Injury Attributed to a Curcumin Supplement

Imam, Z., Khasawneh, M., Jomaa, D., Iftikhar, H., & SayedAhmad, Z. (2019) · Case Reports in Gastrointestinal Medicine · doi:10.1155/2019/6029403 · Cited by 28 · see citing works

A curcumin-based TPA four-branched copper(II) complex probe for in vivo early tumor detection

Pi, Z., Wang, J., Jiang, B., Cheng, G., & Zhou, S. (2014) · Materials Science and Engineering C · doi:10.1016/j.msec.2014.10.061 · Cited by 25 · see citing works

Studies on intramolecular hydrogen bonding between the pyridine nitrogen and the amide hydrogen of the peptide: synthesis and conformational analysis of tripeptides containing novel amino acids with a pyridine ring

Hanyu, M., Ninomiya, D., Yanagihara, R., Murashima, T., Miyazawa, T., & Yamada, T. (2005) · Journal of Peptide Science · doi:10.1002/psc.647 · Cited by 15 · see citing works

Role of Tau Protein in Neurodegenerative Diseases and Development of Its Targeted Drugs: A Literature Review

Yang, J., Zhi, W., & Wang, L. (2024) · Molecules · doi:10.3390/molecules29122812 · Cited by 63 · see citing works

Antioxidant curcumin induces oxidative stress to kill tumor cells (Review)

Hu, Y., Cheng, L., Du, S., Wang, K., & Liu, S. (2023) · Oncology Letters · doi:10.3892/ol.2023.14200 · Cited by 54 · see citing works

The effect of curcumin supplementation on cognitive function: an updated systematic review and meta-analysis

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Cuproptosis: mechanisms and links with Alzheimer’s disease

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