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Antidiabetic Agents from Medicinal Plants

Open access
Jung, Mankil, Park, Moonsoo, Lee, Hyun, Kang, Yoon-Ho, Kang, Eun, Kim, Sang·2006·Current Medicinal Chemistry

Abstract

Currently available therapeutic options for non-insulin-dependent diabetes mellitus, such as dietary modification, oral hypoglycemics, and insulin, have limitations of their own. Many natural products and herbal medicines have been recommended for the treatment of diabetes. The present paper reviews medicinal plants that have shown experimental or clinical antidiabetic activity and that have been used in traditional systems of medicine; the review also covers natural products (active natural components and crude extracts) isolated from the medicinal plants and reported during 2001 to 2005. Many kinds of natural products, such as terpenoids, alkaloids, flavonoids, phenolics, and some others, have shown antidiabetic potential. Particularly, schulzeines A, B, and C, radicamines A and B, 2,5-imino-1,2,5-trideoxy-L-glucitol, beta-homofuconojirimycin, myrciacitrin IV, dehydrotrametenolic acid, corosolic acid (Glucosol), 4-(alpha-rhamnopyranosyl)ellagic acid, and 1,2,3,4,6-pentagalloylglucose have shown significant antidiabetic activities. Among active medicinal herbs, Momordica charantia L. (Cucurbitaceae), Pterocarpus marsupium Roxb. (Leguminoceae), and Trigonella foenum graecum L. (Leguminosae) have been reported as beneficial for treatment of type 2 diabetes.

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Metadata

Authors
Jung, M., Park, M., Lee, H., Kang, Y.-H., Kang, E., & Kim, S.
Venue
Current Medicinal Chemistry
Published
2006-04-01
Volume
13
Issue
10
Pages
1203-1218
ISSN
0929-8673 (ISSN-L)
OpenAlex
W2098548547
Cited by
571
References
0
FWCI
6.86
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Antidiabetic Agents from Medicinal Plants. https://app.cochat.ai/papers/10.2174/092986706776360860
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Jung, M., Park, M., Lee, H., Kang, Y.-H., Kang, E., & Kim, S. (2006). Antidiabetic Agents from Medicinal Plants. Current Medicinal Chemistry. https://doi.org/10.2174/092986706776360860

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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