Potential Therapeutic Effects of Exercise to the Brain
Abstract
Exercise is a well-recognized facet of modern living; however, the threat of sedentary lifestyle is ever increasing with the arrival of the technological period. Although the beneficial effects of exercise to the health and function of the brain have been accepted by the scientific and medical community, much remains to be achieved to understand its mechanisms of action. With the advent of modern investigative tools, several more key molecular and cellular players have been implicated in the above process. Such include the family of neurotrophins (e.g. NGF and BDNF) and their receptors, some pro-inflammatory cytokines (L-1beta, IL-6, TNF-alpha, IFN-gamma), microglia and astrocytes, and the cholinergic neuronal cells in the forebrain. While experiments based on the voluntary exercise paradigm has been the preferred approach to studying the brain, less is known about the forced paradigm. We will discuss in this review how molecular players may feature differently in the context of exercise and more importantly how their actions converged to impact the structure, and function (learning and memory) of the CNS.
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Treadmill exercise improves hippocampus-dependent spatial learning and memory as well as aversive memory.
“Treadmill exercise also improves hippocampus-dependent spatial learning and memory as well as aversive memory [2, 3, 25, 97, 112, 174, 186, 187].”
From The neuropathology of sport (2014) · cites this paper as [3]
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MEEUSEN, R. R. (2003) · VUBIR (Vrije Universiteit Brussel) · Cited by 28 · see citing works
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Physical activity and memory functions: An interventional study
Ruscheweyh, R., Willemer, C., Krüger, K., Duning, T., Warnecke, T., Sommer, J., Völker, K., Ho, H. V., Mooren, F., Knecht, S., et al. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.08.001 · Cited by 499 · see citing works
Williams, R. J., & Spencer, J. P. E. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.09.010 · Cited by 448 · see citing works
Garland, T., Schutz, H., Chappell, M. A., Keeney, B. K., Meek, T. H., Copes, L. E., Acosta, W., Drenowatz, C., Maciel, R. C., van Dijk, G., et al. (2011) · Journal of Experimental Biology · doi:10.1242/jeb.048397 · Cited by 444 · see citing works
McKee, A. C., Daneshvar, D. H., Alvarez, V. E., & Stein, T. D. (2014) · Acta Neuropathologica · doi:10.1007/s00401-013-1230-6 · Cited by 422 · see citing works
Forced and voluntary exercise differentially affect brain and behavior
Leasure, J. L., & Jones, M. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.07.041 · Cited by 335 · see citing works
Exercise exerts neuroprotective effects on Parkinson's disease model of rats
Tajiri, N., Yasuhara, T., Shingo, T., Kondo, A., Yuan, W., Kadota, T., Wang, F., Baba, T., Tayra, J. T., Morimoto, T., et al. (2010) · Brain Research · doi:10.1016/j.brainres.2009.10.075 · Cited by 308 · see citing works
Phenotypic Plasticity: Molecular Mechanisms and Adaptive Significance
Kelly, S. A., Panhuis, T. M., & Stoehr, A. M. (2012) · Comprehensive physiology · doi:10.1002/cphy.c110008 · Cited by 249 · see citing works
Exercise moderates age-related atrophy of the medial temporal lobe
Bugg, J. M., & Head, D. M. (2009) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.03.008 · Cited by 236 · see citing works
Flavonoids and cognition: The molecular mechanisms underlying their behavioural effects
Spencer, J. P. E., Vauzour, D., & Rendeiro, C. (2009) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2009.10.003 · Cited by 228 · see citing works
The impact of flavonoids on memory: physiological and molecular considerations
Spencer, J. P. E. (2009) · Chemical Society Reviews · doi:10.1039/b800422f · Cited by 219 · see citing works
Liu, Y., Chen, H., Wu, C., Kuo, Y., Yu, L., Huang, A., Wu, F., Chuang, J., & Jen, C. J. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2009.173088 · Cited by 199 · see citing works
Moderate treadmill exercise prevents oxidative stress-induced anxiety-like behavior in rats
Salim, S., Sarraj, N., Taneja, M., Saha, K., Tejada-Simon, M. V., & Chugh, G. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.12.039 · Cited by 191 · see citing works
Target Identification for CNS Diseases by Transcriptional Profiling
Altar, C. A., Vawter, M. P., & Ginsberg, S. D. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.172 · Cited by 139 · see citing works
Bahrami, F., Movahedi, A., Marandi, S. M., & Sorensen, C. (2015) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-015-2643-y · Cited by 135 · see citing works
The protective role of exercise against age-related neurodegeneration
Sujkowski, A. L., Hong, L., Wessells, R. J., & Todi, S. V. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101543 · Cited by 134 · see citing works
Reynolds, G., Otto, M. W., Ellis, T. D., & Cronin‐Golomb, A. (2015) · Movement Disorders · doi:10.1002/mds.26484 · Cited by 132 · see citing works
de Almeida, C. A. S., Demaman, A. S., Kusuda, R., Cadetti, F., Ravanelli, M. I. B., Queiroz, A. L., Sousa, T. A. E., Zanon, S., Silveira, L. R., & Lucas, G. (2015) · Pain · doi:10.1097/01.j.pain.0000460339.23976.12 · Cited by 127 · see citing works
Zagaar, M. A., Alhaider, I. A., Dao, A. T., Levine, A. T., Alkarawi, A., Alzubaidy, M., & Alkadhi, K. A. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.12.039 · Cited by 127 · see citing works
Rossi, S., Furlan, R., Chiara, V. D., Musella, A., Giudice, T. L., Mataluni, G., Cavasinni, F., Cantarella, C., Bernardi, G., Muzio, L., et al. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.06.013 · Cited by 123 · see citing works
Treadmill exercise inhibits traumatic brain injury-induced hippocampal apoptosis
Kim, D.-H., Ko, I., Kim, B.-K., Kim, T.-W., Kim, S., Shin, M., Kim, C., Kim, H. K., Kim, K.-M., & Baek, S. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.09.021 · Cited by 122 · see citing works
Physical exercise alleviates debilities of normal aging and Alzheimer’s disease
Archer, T. (2010) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2010.01412.x · Cited by 109 · see citing works
Smith, J. C., Nielson, K. A., Woodard, J. L., Seidenberg, M., Durgerian, S., Antuono, P., Butts, A. M., Hantke, N. C., Lancaster, M. A., & Rao, S. M. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.07.070 · Cited by 111 · see citing works
Alomari, M. A., Khabour, O. F., Alzoubi, K. H., & Alzubi, M. A. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.03.007 · Cited by 107 · see citing works
Szulc, K. U., Timmons, B. W., Bouffet, É., Laughlin, S., de Medeiros, C. B., Skocic, J., Lerch, J. P., & Mabbott, D. (2018) · NeuroImage Clinical · doi:10.1016/j.nicl.2018.02.021 · Cited by 99 · see citing works
Zagaar, M. A., Dao, A. T., Levine, A. T., Alhaider, I. A., & Alkadhi, K. A. (2013) · SLEEP · doi:10.5665/sleep.2642 · Cited by 97 · see citing works
Upper limb motor rehabilitation impacts white matter microstructure in multiple sclerosis
Bonzano, L., Tacchino, A., Brichetto, G., Roccatagliata, L., Dessypris, A., Feraco, P., de Carvalho, M. L. L., Battaglia, M. A., Mancardi, G., & Bove, M. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.12.025 · Cited by 95 · see citing works
Funk, J. A., Gohlke, J. M., Kraft, A. D., McPherson, C. A., Collins, J. B., & Harry, G. J. (2011) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2011.03.012 · Cited by 95 · see citing works
At least eighty percent of brain grey matter is modifiable by physical activity: A review study
Batouli, S. A. H., & Saba, V. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.06.002 · Cited by 92 · see citing works
Nerve growth factor: basic studies and possible therapeutic applications
Manni, L., Rocco, M. L., Bianchi, P., Soligo, M., Guaragna, M., Barbaro, S. P., & Aloe, L. (2013) · Growth Factors · doi:10.3109/08977194.2013.804073 · Cited by 92 · see citing works
Bernardes, D., Oliveira‐Lima, O. C., da Silva, T. V., Faraco, C. C. F., Leite, H. R., Juliano, M. A., dos Santos, D. M., Bethea, J. R., Brambilla, R., Orian, J. M., et al. (2013) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2013.08.014 · Cited by 89 · see citing works
Influence of Physical Exercise on Traumatic Brain Injury Deficits: Scaffolding Effect
Archer, T. (2011) · Neurotoxicity Research · doi:10.1007/s12640-011-9297-0 · Cited by 90 · see citing works
Exercise as a Positive Modulator of Brain Function
Alkadhi, K. A. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0516-4 · Cited by 90 · see citing works
The effects of hormones and physical exercise on hippocampal structural plasticity
Triviño-Paredes, J., Patten, A. R., Gil‐Mohapel, J., & Christie, B. R. (2016) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2016.03.001 · Cited by 83 · see citing works
Correia, P. R., Pansani, A. P., Machado, F., Andrade, M. S., da Silva, A. C., Scorza, F. A., Cavalheiro, É. A., & Arida, R. M. (2010) · Clinics · doi:10.1590/s1807-59322010001100012 · Cited by 79 · see citing works
Mannes, Z. L., Waxenberg, L. B., Cottler, L. B., Perlstein, W. M., Burrell, L. E., Ferguson, E. G., Edwards, M., & Ennis, N. (2018) · International Review of Sport and Exercise Psychology · doi:10.1080/1750984x.2018.1469162 · Cited by 83 · see citing works
The effects of physical activity on psychogenic movement disorders
Dallocchio, C., Arbasino, C., Klersy, C., & Marchioni, E. (2010) · Movement Disorders · doi:10.1002/mds.22952 · Cited by 75 · see citing works
Physical exercise can reverse the deficit in fear memory induced by maternal deprivation
Mello, P. B., Benetti, F., Cammarota, M., & Izquierdo, I. (2009) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2009.04.004 · Cited by 71 · see citing works
Mota, B. C., Pereira, L. B., Souza, M. A., Silva, L. F. A., Magni, D. V., Ferreira, A. P. O., Oliveira, M. S., Furian, A. F., Mazzardo‐Martins, L., da Silva, M. D., et al. (2011) · Neurotoxicity Research · doi:10.1007/s12640-011-9257-8 · Cited by 71 · see citing works
Rambo, L. M., Ribeiro, L. R., Oliveira, M. S., Furian, A. F., Lima, F. D., Souza, M. A., Silva, L. F. A., Retamoso, L. T., Corte, C. L. D., Puntel, G. O., et al. (2009) · Neurochemistry International · doi:10.1016/j.neuint.2009.04.007 · Cited by 69 · see citing works
Treadmill Exercise Induces Hippocampal Astroglial Alterations in Rats
Bernardi, C. L., Tramontina, A. C., Nardin, P., Biasibetti, R., Costa, A. P., Vizuete, A. F. K., Batassini, C., Tortorelli, L. S., Wartchow, K. M., Dutra, M. F., et al. (2013) · Neural Plasticity · doi:10.1155/2013/709732 · Cited by 68 · see citing works
Patki, G., Solanki, N., Atrooz, F., Ansari, A., Allam, F., Jannise, B., Maturi, J., & Salim, S. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.04.011 · Cited by 67 · see citing works
Lima, F. D., Oliveira, M. S., Furian, A. F., Souza, M. A., Rambo, L. M., Ribeiro, L. R., Silva, L. F. A., Retamoso, L. T., Hoffmann, M. S., Magni, D. V., et al. (2009) · Brain Research · doi:10.1016/j.brainres.2009.04.052 · Cited by 67 · see citing works
Voluntary Exercise Increases Oligodendrogenesis in Spinal Cord
Krityakiarana, W., Monteros, A. E. D. L., Ghiani, C. A., Zhao, P. M., Topaldjikian, N., Gómez‐Pinilla, F., Yamaguchi, M., Kotchabhakdi, N., & de Vellis, J. (2010) · International Journal of Neuroscience · doi:10.3109/00207450903222741 · Cited by 65 · see citing works
Wnt pathway regulation by long-term moderate exercise in rat hippocampus
Bayod, S., Menella, I., Sanchez‐Roige, S., Lalanza, J. F., Escorihuela, R. M., Camins, A., Pallàs, M., & Canudas, A. M. (2013) · Brain Research · doi:10.1016/j.brainres.2013.10.048 · Cited by 62 · see citing works
Byl, N. N., Archer, E. S., & McKenzie, A. L. (2009) · Journal of Hand Therapy · doi:10.1016/j.jht.2008.12.003 · Cited by 61 · see citing works
Role of Neurotrophic Factors in Behavioral Processes
Pardon, M. (2010) · Vitamins and hormones · doi:10.1016/s0083-6729(10)82010-2 · Cited by 60 · see citing works
Exercise Paradigms to Study Brain Injury Recovery in Rodents
Arida, R. M., Scorza, F. A., da Silva, S. G., Cysneiros, R. M., & Cavalheiro, É. A. (2011) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0b013e3182063a9c · Cited by 57 · see citing works
Immune senescence and brain aging: can rejuvenation of immunity reverse memory loss?
Ron‐Harel, N., & Schwartz, M. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2009.03.003 · Cited by 56 · see citing works
Khabour, O. F., Alzoubi, K. H., Alomari, M. A., & Alzubi, M. A. (2012) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2012.08.005 · Cited by 54 · see citing works
Campos, C., Rocha, N., Lattari, E., Paes, F., Nardi, A. E., & Machado, S. E. D. C. (2016) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2016.1179582 · Cited by 54 · see citing works
Neurodegenerative diseases: exercising towards neurogenesis and neuroregeneration
Ang, E. (2010) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2010.00025 · Cited by 51 · see citing works
Self-citationThe Effect of Acute Exercise on Encoding and Consolidation of Long-Term Memory
Labban, J. D., & Etnier, J. L. (2018) · Journal of Sport and Exercise Psychology · doi:10.1123/jsep.2018-0072 · Cited by 48 · see citing works
de Castro, M. R. T., Ferreira, A. P. D. O., Busanello, G. L., da Silva, L. R. H., da Silveira, M. E. P., Fiorin, F. D. S., Arrifano, G. D. P., Lopez, M. E. C., Barcelos, R. P., Cuevas, M. J., et al. (2017) · The Journal of Physiology · doi:10.1113/jp273933 · Cited by 47 · see citing works
Liu, X. Z., Yang, L. J., Fan, S. J., Jiang, H., & Pan, F. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.04.011 · Cited by 46 · see citing works
Zagaar, M. A., Dao, A. T., Alhaider, I. A., & Alkadhi, K. A. (2013) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2013.07.011 · Cited by 45 · see citing works
Salari, M., Sheibani, V., Saadati, H., Pourrahimi, A. M., Khaksari, M., Esmaeelpour, K., & Khodamoradi, M. (2015) · Behavioural Processes · doi:10.1016/j.beproc.2015.06.014 · Cited by 41 · see citing works
Antistress properties of antidepressant drugs and their clinical implications
Calabrese, F., Molteni, R., & Riva, M. A. (2011) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2011.05.007 · Cited by 41 · see citing works
Arévalo, M. T. V., Duarte, C., Salazar, I. C., Soto, L. F. L., & Tamayo, J. A. (2011) · TSpace (University of Toronto) · Cited by 41 · see citing works
Graziano, A., Foffani, G., Knudsen, E. B., Shumsky, J. S., & Moxon, K. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0054350 · Cited by 41 · see citing works
Association of Physical Exercise on Anxiety and Depression Amongst Adults.
Khanzada, F. J., Soomro, N. N., & Khan, S. Z. (2015) · PubMed · Cited by 41 · see citing works
Tanehkar, F., Rashidy‐Pour, A., Vafaei, A. A., Sameni, H. R., Haghighi, S., Miladi‐Gorji, H., Motamedi, F., Akhavan, M. M., & Bavarsad, K. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.10.003 · Cited by 39 · see citing works
Prior regular exercise prevents synaptic plasticity impairment in sleep deprived female rats
Saadati, H., Sheibani, V., Esmaeili‐Mahani, S., Hajali, V., & Mazhari, S. (2014) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2014.09.009 · Cited by 37 · see citing works
Radahmadi, M., Hosseini, N., & Alaei, H. (2016) · Brain Research · doi:10.1016/j.brainres.2016.09.045 · Cited by 38 · see citing works
Can Exercise Make You Smarter, Happier, and Have More Neurons? A Hormetic Perspective
Gradari, S., Pallé, A., McGreevy, K. R., Fontán‐Lozano, Á., & Trejo, J. L. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00093 · Cited by 37 · see citing works
Does a period of detraining cause a decrease in serum brain-derived neurotrophic factor?
Goekint, M., Roelands, B., Pauw, K. D., Knaepen, K., Bos, I., & MEEUSEN, R. R. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.09.032 · Cited by 34 · see citing works
Soltani, N., Soltani, Z., Khaksari, M., Ebrahimi, G., Hajmohammadi, M., & Iranpour, M. (2019) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-019-00753-w · Cited by 33 · see citing works
Phenotypic Plasticity: Molecular Mechanisms and Adaptive Significance
Kelly, S. A., Panhuis, T. M., & Stoehr, A. M. (2012) · Comprehensive physiology · doi:10.1002/j.2040-4603.2012.tb00423.x · Cited by 33 · see citing works
Wei, D., Hurd, C., Galleguillos, D., Singh, J., Fenrich, K. K., Webber, C. A., Sipione, S., & Fouad, K. (2016) · Experimental Neurology · doi:10.1016/j.expneurol.2016.07.001 · Cited by 28 · see citing works
Prior treadmill exercise promotes resilience to vicarious trauma in rats
Kochi, C., Liu, H., Zaidi, S., Atrooz, F., Dantoin, P., & Salim, S. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.04.018 · Cited by 28 · see citing works
Landers, M. R., Kinney, J. W., Allen, D. N., & van Breukelen, F. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.04.002 · Cited by 28 · see citing works
Passive cycling in neurorehabilitation after spinal cord injury: A review
Nardone, R., Orioli, A., Golaszewski, S. M., Brigo, F., Sebastianelli, L., Höller, Y., Frey, V., & Trinka, E. (2016) · Journal of Spinal Cord Medicine · doi:10.1080/10790268.2016.1248524 · Cited by 26 · see citing works
Turğut, M., Çınar, V., Pala, R., Tuzcu, M., Orhan, C., Telçeken, H., Şahin, N., Deeh, P. B. D., Komorowski, J. R., & Şahin, K. (2018) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-018-0249-4 · Cited by 26 · see citing works
Endurance training on rodent brain antioxidant capacity: A meta-analysis
de Souza, R. F., de Moraes, S. R. A., Augusto, R. L., Zanona, A. D. F., de Matos, D. G., Aidar, F. J., & Andrade‐da‐Costa, B. L. D. S. (2018) · Neuroscience Research · doi:10.1016/j.neures.2018.09.002 · Cited by 26 · see citing works
Neuroprotection of Early Locomotor Exercise Poststroke: Evidence From Animal Studies
Zhang, P., Xianglei, J., Hongbo, Y., Zhang, J., & Xu, C. (2015) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/cjn.2015.39 · Cited by 25 · see citing works
Peng, S., Fang, Y., Othman, A. T., & Liang, J. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.940977 · Cited by 26 · see citing works
Increased Nerve Growth Factor Serum Levels in Top Athletes
Bonini, M., Fioretti, D. P., Sargentini, V., Giacco, S. D., Rinaldi, M., Tranquilli, C., & Bonini, S. (2012) · Clinical Journal of Sport Medicine · doi:10.1097/jsm.0b013e31827ee6d5 · Cited by 24 · see citing works
Bernardes, D., & de Oliveira, A. L. R. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00950 · Cited by 24 · see citing works
Cognitive Impairments of Sleep-Deprived Ovariectomized (OVX) Female Rats by Voluntary Exercise
Rajizadeh, M. A., Esmaeilpour, K., Motamedy, S., Borzadaran, F. M., & Sheibani, V. (2020) · Basic and Clinical Neuroscience Journal · doi:10.32598/bcn.9.10.505 · Cited by 25 · see citing works
Arévalo, M. T. V., Duarte, C., Salazar, I. C., Soto, L. F. L., & Tamayo, J. A. (2019) · Colombia medica · doi:10.25100/cm.v42i3.872 · Cited by 57 · see citing works
Treadmill running protects spinal cord contusion from secondary degeneration
de Andrade, M. S. R., de Mendonça, L. M. F., & Chadi, G. (2010) · Brain Research · doi:10.1016/j.brainres.2010.05.070 · Cited by 23 · see citing works
Wolf, W. A., Martin, J. W., Kartje, G. L., & Farrer, R. G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108031 · Cited by 22 · see citing works
Alomari, M. A., Khabour, O. F., Alawneh, K. M., Alzoubi, K. H., & Maikano, A. B. (2020) · Heliyon · doi:10.1016/j.heliyon.2020.e03490 · Cited by 22 · see citing works
Ganzer, P. D., Manohar, A., Shumsky, J. S., & Moxon, K. A. (2016) · Experimental Neurology · doi:10.1016/j.expneurol.2016.01.022 · Cited by 17 · see citing works
The effect and mechanism of exercise for post-stroke pain
Ma, Y., Luo, J., & Wang, X. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.1074205 · Cited by 17 · see citing works
Uhlendorf, T. L., Kummer, B. H. V., Yaspelkis, B. B., & Cohen, R. W. (2010) · Brain Research · doi:10.1016/j.brainres.2010.10.094 · Cited by 17 · see citing works
Kavyannejad, R., Karimian, S. M., Riahi, E., & Ashabi, G. (2022) · Metabolic Brain Disease · doi:10.1007/s11011-022-00985-8 · Cited by 16 · see citing works
Bajracharya, R., & Ballard, J. W. O. (2018) · Fly · doi:10.1080/19336934.2018.1482139 · Cited by 13 · see citing works
Jang, Y., Lee, B., Kim, E., Shim, W., Yang, Y. D., & Kim, S. M. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.11.153 · Cited by 13 · see citing works
Watve, M. (2012) · Springer eBooks · doi:10.1007/978-1-4614-4409-1_7 · Cited by 13 · see citing works
Nardone, R., Langthaler, P., Bathke, A., Höller, Y., Brigo, F., Lochner, P., Christova, M., & Trinka, E. (2016) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2016.04.012 · Cited by 13 · see citing works
Jensen, S. K., & Yong, V. W. (2014) · Clinical and Experimental Neuroimmunology · doi:10.1111/cen3.12093 · Cited by 12 · see citing works
Exercise and Dietary Restriction for Promotion of Neurohealth Benefits
Archer, T., & Garcia, D. (2015) · Health · doi:10.4236/health.2015.71016 · Cited by 10 · see citing works
Chen, K., Ge, R., Cheng, Y., & Dai, Y. (2019) · Experimental Brain Research · doi:10.1007/s00221-019-05647-3 · Cited by 10 · see citing works
Cheon, S.-H., & Koo, H.-M. (2013) · Journal of Physical Therapy Science · doi:10.1589/jpts.25.321 · Cited by 8 · see citing works
Larger Volume and Different Activation of the Brain in Response to Threat in Military Officers
Batouli, S. A. H., & Saba, V. (2020) · Basic and Clinical Neuroscience Journal · doi:10.32598/bcn.11.5.352.4 · Cited by 7 · see citing works
Papalia, W. L., Nascimento, A. S., Krishna, G., Cunha, N. B., Furian, A. F., Oliveira, M. S., Royes, L. F. F., & Fighera, M. R. (2021) · Molecular Neurobiology · doi:10.1007/s12035-021-02639-9 · Cited by 6 · see citing works
Determinants of regeneration in the injured nervous system
Selzer, M. A., Clarke, S., Cohen, L. G., Kwakkel, G., & Miller, R. H. (2014) · Cambridge University Press eBooks · doi:10.1017/cbo9780511995583.025 · Cited by 6 · see citing works
Chen, J.-W., Guan, Y., Zheng, Y.-L., & Zhu, K. N. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.977100 · Cited by 6 · see citing works
Effects of Voluntary Exercise on Motor Function in Parkinson's disease Model of Rats
Rafie, F., Shabazi, M., Sheikh, M., Naghdi, N., & Sheibani, V. (2017) · Annals of Applied Sport Science · doi:10.18869/acadpub.aassjournal.5.2.81 · Cited by 6 · see citing works
- Authors
- Ang, E., Gomez-Pinilla, F., Ang, E., & Gomez-Pinilla, F.
- Venue
- Current Medicinal Chemistry
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2007-10-01
- Volume
- 14
- Issue
- 24
- Pages
- 2564-2571
- ISSN
- 0929-8673 (ISSN-L)
- OpenAlex
- W2134225473
- Cited by
- 129
- References
- 1
- Citations by year
- 2025: 3 · 2022: 6 · 2021: 3 · 2020: 5 · 2019: 5 · 2018: 9 · 2017: 8 · 2016: 9 · 2015: 10 · 2014: 7 · 2013: 13 · 2012: 9
- FWCI
- 3.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Medicinal Chemistry (publishedVersion)
- PubMed (publishedVersion)
- National University of Singapore (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- physical activity, brain, neurotrophins, brain-derived neurotrophic factor, nerve growth factor, inflammatory cytokines, microglia, astrocytes, cholinergic neurons, voluntary exercise, forced exercise, learning and memory, sedentary lifestyle, neuroplasticity
- MeSH terms
- Animals, Brain, Disease, Humans, Physical Conditioning, Animal, Exercise
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