Mitochondrial Respiratory Complex I: Structure, Function and Implication in Human Diseases

Sequence and organization of the human mitochondrial genome

Anderson, S., Bankier, A. T., Barrell, B. G., de Bruijn, M. H. L., Coulson, A. R., Drouin, J., Eperon, I. C., Nierlich, D. P., Roe, B. A., Sanger, F., et al. (1981) · Nature · doi:10.1038/290457a0 · Cited by 9,740

Parkinson's Disease

Dauer, W., & Przedborski, S. (2003) · Neuron · doi:10.1016/s0896-6273(03)00568-3 · Cited by 5,469

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

Langston, J. W., Ballard, P., Tetrud, J. W., & Irwin, I. (1983) · Science · doi:10.1126/science.6823561 · Cited by 4,914

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

Betarbet, R. S., Sherer, T., MacKenzie, G. M., Garcia‐Osuna, M., Panov, A. V., & Greenamyre, J. T. (2000) · Nature Neuroscience · doi:10.1038/81834 · Cited by 3,770

Mitochondrial control of cell death

Kroemer, G., & Reed, J. C. (2000) · Nature Medicine · doi:10.1038/74994 · Cited by 3,103

Mitochondrial DNA mutation associated with Leber’s hereditary optic neuropathy

Wallace, D. C., Singh, G., Lott, M. T., Hodge, J. A., Schurr, T. G., Lezza, A. M. S., Elsas, L. J., & Nikoskelainen, E. K. (1988) · Science · doi:10.1126/science.3201231 · Cited by 2,440

Untitled work

(2001) · PubMed · Cited by 2,381

Mitochondrial Complex I Deficiency in Parkinson's Disease

Schapira, A. H. V., Cooper, J. M., Dexter, D., Clark, J. B., Jenner, P., & Marsden, C. D. (1990) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1990.tb02325.x · Cited by 2,283

Mitochondria, oxidative stress and cell death

Ott, M., Gogvadze, V. G., Orrenius, S., & Zhivotovsky, B. (2007) · APOPTOSIS · doi:10.1007/s10495-007-0756-2 · Cited by 2,020

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

Pagliarini, D. J., Calvo, S. E., Chang, B., Sheth, S. A., Vafai, S. B., Ong, S.-E., Walford, G. A., Sugiana, C., Boneh, A., Chen, W. K., et al. (2008) · Cell · doi:10.1016/j.cell.2008.06.016 · Cited by 1,994

Impaired mitochondrial morphological plasticity and failure of mitophagy associated with the G11778A mutation of LHON

Pasqualotto, B. A., Nelson, A., Deheshi, S., Sheldon, C. A., Vogl, A. W., & Rintoul, G. L. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.150119 · Cited by 2

ATP-binding cassette family C member 1 constrains metabolic responses to high-fat diet in male mice

Villalobos, E., Miguelez-Crespo, A., Morgan, R., Ivatt, L., Paul, M. A., Simpson, J., Homer, N. Z. M., Kurian, D., Aguilar, J., Kline, R., et al. (2024) · Journal of Endocrinology · doi:10.1530/joe-24-0024 · Cited by 2

Echocardiographic surrogate of left ventricular stroke work in a model of brain stem death donors

Sato, K., Hoe, L. E. S., Chan, J. H., Obonyo, N. G., Wildi, K. S., Heinsar, S., Colombo, S. M., Ainola, C., Abbate, G., Sato, N., et al. (2024) · European Journal of Clinical Investigation · doi:10.1111/eci.14259 · Cited by 2

The absence of canonical respiratory complex I subunits in male-type mitogenomes of three Donax species

Burzyński, A., Śmietanka, B., Fernández‐Pérez, J., & Lubośny, M. (2024) · Scientific Reports · doi:10.1038/s41598-024-63764-8 · Cited by 2

Neuroprotective and anti-inflammatory properties of proteins secreted by glial progenitor cells derived from human iPSCs

Salikhova, D. I., Shedenkova, M. O., Sudina, A. K., Belousova, E. V., Krasilnikova, I. A., Nekrasova, A. A., Nefedova, Z. A., Frolov, D., Fatkhudinov, T., Макаров, А. В., et al. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1449063 · Cited by 2

Mito-specific cascade amplifier sniping metabolism homeostasis for multimodal imaging-guided antitumor bioenergetic therapy

Yang, J., Zhang, Y., Chu, M., Qian, J., Liu, J., Wang, M., Qiang, Z., & Ren, J. (2024) · Nano Research · doi:10.1007/s12274-024-6892-y · Cited by 2

In vitro modelling of Parkinson's disease using 6-OHDA is associated with increased NQO2 activity

Verbovaya, E. R., Андреевич, К. И., Logvinov, I. O., Антипова, Т. А., Воронин, М. В., & Середенин, С. Б. (2024) · Toxicology in Vitro · doi:10.1016/j.tiv.2024.105940 · Cited by 2

Cross-Species Studies Reveal That Dysregulated Mitochondrial Gene Expression and Electron Transport Complex I Activity Are Crucial for Sarcopenia

Lee, J.-Y., Shin, S., Han, J. E., Kwon, E., & Bae, H. R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms251910302 · Cited by 2

Mitogenome based adaptations and phylogeny of Beetal goats in India

Thomas, M., Sukumaran, J., Rojan, P. M., Venkatachalapathy, R. T., Aravindakshan, T. V., King, J. S., & Akhila, M. R. (2024) · Gene Reports · doi:10.1016/j.genrep.2024.102094 · Cited by 2

Exploring Alternate Targets for Respiratory Resuscitation in Patients With Sepsis and Septic Shock

Richardson, L. A., Bagunu, K., Doughty, K., Concilio, L., Jaime, S., Westcott, A., & Graham, J. (2025) · Critical Care Nursing Quarterly · doi:10.1097/cnq.0000000000000547 · Cited by 2

A Rare ND5 Mutation Causing Leber’s Hereditary Optic Neuropathy

Pandya, B. U., Vosoughi, A. R., Jhaveri, A., & Micieli, J. A. (2023) · Case Reports in Ophthalmology · doi:10.1159/000529423 · Cited by 2

Neuroprotective effects of carnitinoid compounds in rodent cellular and in vivo models of mitochondrial complex I dysfunction

Hoffman, M. E., Augsburger, B. N., Foradori, C. D., Parameshwaran, K., Helsper, S., Marable, J., Steliou, K., Pinkert, C. A., & Irwin, M. H. (2019) · OpenBU (Boston University) · Cited by 2

A novel bi-allelic variant in the SDHB gene causes a severe mitochondrial complex II deficiency: a case report

Solmaz, A. E., Parıltay, E., Talim, B., & Önay, H. (2021) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2021.107039 · Cited by 2

Applications of Taurine in the Central Nervous System Disorders Linked with Mitochondrial Impairment

Heidari, R., & Ommati, M. M. (2023) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815124484123010005 · Cited by 2

Ribosomal DNA copy number alteration in blood sample from gastric cancer patients

Chen, C., Feng, L., Chen, J., Shen, J. F., & Lin, L. (2023) · Molecular Biology Reports · doi:10.1007/s11033-023-08630-y · Cited by 2

Characterization of the Complete Mitochondrial Genome of Agelas nakamurai from the South China Sea

Lu, Z., Lin, Q., & Zhang, H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010357 · Cited by 2

The metabolic response of Pseudomonas taiwanensis to NADH dehydrogenase deficiencyPreprint

Nies, S. C., Dinger, R., Chen, Y., Wordofa, G. G., Kristensen, M., Schneider, K. P., Büchs, J., Petzold, C. J., Keasling, J. D., Blank, L. M., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/624536 · Cited by 2

Mitochondrial Defects in the Respiratory Complex I Contribute to Impaired Translational Initiation via ROS and Energy Homeostasis in SMA Motor NeuronsPreprint

Thelen, M. P., Wirth, B., & Kye, M. J. (2020) · Research Square · doi:10.21203/rs.3.rs-49251/v1 · Cited by 2

Energy metabolism of cardiac pumping

Hickey, A. J., Harford, A. R., & Devaux, J. B. L. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-90801-6.00128-2 · Cited by 2

Antibody-Based Targeting of the SPP1-CD44 Axis in Pediatric High-Grade Glioma through Single-Cell and Structural BioinformaticsPreprint

Limbu, S., & Kumar, A. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.01.651763 · Cited by 2

Hypothalamic transcriptome analysis reveals male-specific differences in molecular pathways related to oxidative phosphorylation between Iberian pig genotypes

Heras-Molina, A., Núñez, Y., Benítez, R., Pacheco, J. L. P., García-Contreras, C., Vázquez-Gómez, M., Astiz, S., Isabel, B., Gonzalez‐Bulnes, A., & Óvilo, C. (2022) · PLoS ONE · doi:10.1371/journal.pone.0272775 · Cited by 2

Robust assembly of electron transfer chain in the brain of Naked Mole-Rat during aging

Liang, T. B., Bernal, B., Qi, W., Ikeno, Y., Salmon, A. B., Kwok, D., Michalek, J. E., Zhou, M., & Bai, Y. (2024) · Organelle · doi:10.61747/0ifp.202408002 · Cited by 1

Mitochondrial Function and Bioenergetics

Stowe, D. F. (2025) · Springer eBooks · doi:10.1007/978-3-031-76668-8_5 · Cited by 1

Adipose tissue transcriptome in patients switching efavirenz or a protease inhibitor to raltegravir compared to people without HIV

Hanttu, A. M., Muniandy, M., van der Kolk, B. W., Lindgren, H., Yadav, B., Sutinen, J., & Pietiläinen, K. H. (2025) · AIDS · doi:10.1097/qad.0000000000004131 · Cited by 1

NDUFS1 upregulates ENaCα by NAD+ to promote alveolar fluid clearance in acute lung injury

Wang, M., Chen, M., Zhu, J., Zhang, Y., Lü, J., Yue, Z., Yang, Z., & Wang, R. (2025) · International Journal of Medical Sciences · doi:10.7150/ijms.112248 · Cited by 1

Reactive oxygen species in general

Haidara, M. A., Zarić, B. L., Mubarak, H. A., Dawood, A. F., Ebrahim, H. A., Hassan, F. E., ShamsEldeen, A. M., & Yassin, H. Z. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-27333-9.00002-6 · Cited by 1

Minimal Risk Doses of Cadmium Exposure Induce Histological and Functional Alterations in the Brown Adipose Tissue of Wistar Rats

Sarmiento-Ortega, V. E., Castillo-Pérez, D., Moroni-González, D., Díaz, A., Vázquez‐Roque, R. A., Brambila, E., & Treviño, S. (2025) · Biological Trace Element Research · doi:10.1007/s12011-025-04844-2 · Cited by 1

Defining treatment-resistant brain cancer: Genetic screening to identify oncogene-driven immunomodulation and therapy resistance

Myers, Z. D., & Matosevic, S. (2025) · Cancer Gene Therapy · doi:10.1038/s41417-025-00980-y · Cited by 2

Targeting the Rho/ROCK Signaling Pathway Mitigates Mitochondrial Dysfunction in 6-OHDA-Induced Models of Parkinson’s Disease, Both In Vivo and In Vitro

Güçlü, E., İnan, S. Y., Güneş, C. E., & Vural, H. C. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05419-x · Cited by 2

Altered Co-Expression Patterns of Mitochondrial NADH-Dehydrogenase Genes in the Prefrontal Cortex of Rodent ADHD Models

Sylko, P. A., Gromova, A. A., Fesenko, Z. S., Kanov, E. V., Volnova, A. B., Gainetdinov, R. R., & Vaganova, A. N. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262211079 · Cited by 1

A novel transdermal curcumin gel shows potential in improving cardiac bioenergetic functions in Berkeley sickle cell mice

Jana, S., Hicks, W. A., Garbus, H., Goel, Y., Prince, R., Friedman, J. M., Gupta, K., & Alayash, A. I. (2025) · Blood Vessels Thrombosis & Hemostasis · doi:10.1016/j.bvth.2025.100131 · Cited by 1

Maternal slow-release nitrogen diets during late gestation optimize the energy metabolism in calves’ skeletal muscle

Costa, T. C., Cediel-Devia, D. C., Ramírez-Zamudio, G. D., Nascimento, K. B., Gionbelli, M. P., & Duarte, M. A. F. [. (2026) · PLoS ONE · doi:10.1371/journal.pone.0338860 · Cited by 1

Impaired taurine transport contributes to bronchopulmonary dysplasia: a systems biology analysis

Jing, X., Wang, Y., Roethle, M. F., Jia, S., Teng, M., Konduri, G. G., Hessner, M. J., Pritchard, K. A., Day, B. W., Jin, Y., et al. (2026) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1093/ajrcmb/aanag033 · Cited by 1

Gill dysfunction and metabolic disruption: the size-dependent effects of microplastics on Chiromantes haematocheir

Tay, Y. J., Liang, J., Yang, Y., Ren, D., Ma, X., Bao, M., Zhou, Z., Han, M., Li, Z., Abdullah, A. L. B., et al. (2026) · Marine Environmental Research · doi:10.1016/j.marenvres.2026.108158 · Cited by 1

Electron transport chain complex I and mitochondrial fusion regulate ROS for differentiation in Drosophila neural stem cells

Verma, R. K., Bhingare, A., Dubal, D., & Rikhy, R. (2026) · Stem Cell Reports · doi:10.1016/j.stemcr.2026.102951 · Cited by 1

Mitochondrial genome alterations in cancer: From mutations and epigenetics to targeted therapiesack

Shetty, S., Padmasali, N. M., Adiga, D., & Kabekkodu, S. P. (2026) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2026.154218 · Cited by 1

Oxidative stress and inflammation in neurodegenerative disorders

Jomová, K., Alomar, S. Y., Valko, R., Nepovimová, E., Kuča, K., & Valko, M. (2026) · Archives of Toxicology · doi:10.1007/s00204-026-04518-5 · Cited by 1

A Multi-Ingredient Nutritional Supplement Exerts Antiapoptotic and Proliferative Effects on Rat Neural Stem Cells: A Novel Therapeutic Option

Mosadegh, M., Khalkhali, A., & Erfani, Y. (2022) · Re GEN Open · doi:10.1089/regen.2022.0002 · Cited by 1

Signals of differential introgression in the genome of natural hybrids of Caribbean anoles

Farleigh, K., Ascanio, A., Farleigh, M. E., Schield, D. R., Card, D. C., Leal, M., Castoe, T. A., Ježková, T., & Rodríguez‐Robles, J. A. (2023) · Molecular Ecology · doi:10.1111/mec.17170 · Cited by 1

Potential dual inhibitors of Hexokinases and mitochondrial complex I discovered through machine learning approach

Ibezim, A., Onah, E., Osigwe, S. C., Okoroafor, P. U., Ukoha, O. P., Siqueira-Neto, J. L., Ntie‐Kang, F., & Ramanathan, K. (2024) · Scientific African · doi:10.1016/j.sciaf.2024.e02226 · Cited by 1

End-ischemic pharmacological cocktail treatment to mitigate rewarming/reperfusion injury

Malkus, L., Bertram, S., von Horn, C., & Minor, T. (2024) · Cryobiology · doi:10.1016/j.cryobiol.2024.104904 · Cited by 1

Reduced expression of the serotonin transporter impacts mitochondria in a sexually dimorphic manner

Thorne, B. N., Ellenbroek, B. A., & Day, D. J. (2024) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2024.101895 · Cited by 1

“Mighty-chondrial” DNA repair for mitigation of cardiac injury: focus on “A novel mtDNA repair fusion protein attenuates maladaptive remodeling and preserves cardiac function in heart failure”

Chen, Q., & Salloum, F. N. (2017) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00661.2017 · Cited by 1

Expression of complexes I, II and IV in the SGNs of noise-stimulated rats was decreased, and mitochondrial energy metabolism was disturbed, mediating the damage and degeneration of SGNsPreprint

Ding, Z. J., Wang, Y., Wang, R. F., Mi, W., Qiu, J. H., & Zha, D. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.08.19.504483 · Cited by 1

Mitochondrial abundance and function in the serotonin transporter knockout model: a sexually dimorphic association

Thorne, B. N. (2023) · Open Access Victoria University of Wellington | Te Herenga Waka (Figshare) · doi:10.26686/wgtn.22714660 · Cited by 1

The metabolic costs of meiotic drivePreprint

Bradshaw, S. L., Rodríguez, E., Wang, H., Yu, C. T., Noue, C. D. V. D. L., Hafezjee, A., Pomiankowski, A., & Camus, M. F. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.24.620073 · Cited by 1

Genetic and environmental interactions outweigh mitonuclear coevolution for complex traits in DrosophilaPreprint

Darwin, L. J., Lemieux, F. A., Bachtel, R. Z., Blocker, J. H., Brown, C. P., Griffin, A. D., Lerman, J. D., Maule, O. C., Raynes, Y., & Rand, D. M. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.11.24.689096 · Cited by 1

Chaîne respiratoire et pore de transition de perméabilité mitochondriale dans la cardioprotection

Li, B. (2009) · theses.fr (ABES) · doi:10.70675/53a81cafz7ff6z4866z9cbfzc2644e901846 · Cited by 1

A study of glutathione peroxidase 4 function in human intestinal epithelial cells

Ezea, P. C. (2013) · Cited by 1

Neuroprotective effects of carnitinoid antioxidants in rodent models of mitochondrial dysfunction

Hoffman, M. E. (2016)

In situ analysis of mitochondrial respiratory capacity - foundation for cellular physiology

Garipi, E., Rakovac, A., Barak, O. F., Lukač, D., Naumović, N., Drapšin, M., Karaba, D., Popadić-Gaćeša, J., Klasnja, A. V., Slavić, D., et al. (2017) · Medicinski pregled · doi:10.2298/mpns1712445g

Smooth Muscle Cell Mitochondrial Respiration – Effects of Aerobic Training and Type I Diabetes

Yadao, D.-R. R. (2018) · Spectrum Research Repository (Concordia University)

Metabolic adaptations of neurons to physiological oxygen concentrations

Warde, M. (2018) · Gredos (University of Salamanca) · doi:10.14201/gredos.139770

Analysis of differences in the stability of proteins encoded in mitochondrial DNA of model organisms

Kowal, K., Bownik, A., Tkaczyk‐Wlizło, A., & Ślaska, B. (2019) · Medycyna Weterynaryjna · doi:10.21521/mw.6340

Discovery of pharmaceutically-targetable pathways and prediction of survivorship for pneumonia and sepsis patients from the view point of ensemble gene noisePreprint

de Jong, T. V., Guryev, V., & Moshkin, Y. M. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.10.035717

Next Generation Sequencing in diagnosis of mitochondrial epilepsy

Khamdiyeva, O., Tileulesa, Z. B., Baratzhanova, G., Мурзатаева, С., Khussainova, E., Abdikerim, S., Childebayeva, A., & Djansugurova, L. (2020) · International Journal of Biology and Chemistry · doi:10.26577/ijbch.2020.v13.i2.07

Effect of Western Diet and Caloric Substitution with Apple Pomace on Fatty Acid Composition and Gene Expression in the Hypothalamus of Growing Female Sprague-Dawley Rats

Alawadi, A. (2020) · doi:10.33915/etd.7957

Reactive Oxygen Species Affects on Mitochondrial Dynamicity Which May Leads to Parkinson’s DiseasePreprint

Chakraborty, P. (2020) · SSRN Electronic Journal · doi:10.2139/ssrn.3573321

The Pre-Conception Maternal Exposure To Sofosbuvir Impacts The Mitochondrial Biogenesis In Prenatal Fetal Tissues: Experimental Study On RatsPreprint

Shaker, S. A., Abdel-Aziz, M. M., Khafaga, R. H. M., Hafez, H. A., Kamel, M. A. E.-N., & Mahmoud, S. A. (2021) · Research Square · doi:10.21203/rs.3.rs-929365/v1

Investigating the Mechanisms of Action of Metformin at Pharmacological Dose.

Motaib, S. A. (2021) · NCSU Libraries Repository (North Carolina State University Libraries)

Transcriptomic Analysis of Human Endometrium Stromal Cells During Early Embryo Implantation (Within 48 Hour) in VitroPreprint

Han, S., Liu, M., Liu, S., & Li, Y. (2020) · doi:10.21203/rs.3.rs-99005/v1

Dawn of a new era in sponge biotechnology

Hesp, K. (2021) · doi:10.18174/540280

Peer Review #1 of "The complete mitogenome of Arion vulgaris Moquin-Tandon, 1855 (Gastropoda: Stylommatophora): mitochondrial genome architecture, evolution and phylogenetic considerations within Stylommatophora (v0.1)"

(2020) · PeerJ · doi:10.7287/peerj.8603v0.1/reviews/1

Faculty Opinions recommendation of Breast milk alkylglycerols sustain beige adipocytes through adipose tissue macrophages.

Symonds, M. E. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.735757599.793560230

Understanding Pikfyve Control Of Lysome Dynamics

Saffi, G. T. (2021) · doi:10.32920/ryerson.14651847

Peer Review #1 of "The complete mitogenome of Arion vulgaris Moquin-Tandon, 1855 (Gastropoda: Stylommatophora): mitochondrial genome architecture, evolution and phylogenetic considerations within Stylommatophora (v0.2)"

(2020) · PeerJ · doi:10.7287/peerj.8603v0.2/reviews/1

Understanding Pikfyve Control Of Lysome Dynamics

Saffi, G. T. (2021) · doi:10.32920/ryerson.14651847.v1

Peer Review #2 of "The complete mitogenome of Arion vulgaris Moquin-Tandon, 1855 (Gastropoda: Stylommatophora): mitochondrial genome architecture, evolution and phylogenetic considerations within Stylommatophora (v0.1)"

(2020) · PeerJ · doi:10.7287/peerj.8603v0.1/reviews/2

Evre 4 ve 5 Kronik Böbrek Hastaları Metformin Kullanmamalı mı?

Çiftçioğlu, M. (2022) · Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi · doi:10.17517/ksutfd.1181458

Efeito do desacoplamento mitocondrial no processo de criopreservação de espermatozoides ovinos

Frias, H. T. (2022) · doi:10.11606/d.10.2022.tde-01122022-145903

Expression of complexes I, II and IV decreased in SGNs of noise-stimulated rats, mediating the damage and degeneration of SGNsPreprint

Ding, Z.-J., Wang, Y., Wang, R., Mi, W., Qiu, J., & Zha, D.-J. (2023) · Research Square · doi:10.21203/rs.3.rs-2563975/v1

Assessment of mitochondrial function in neurotoxicology using alternative model organisms

(2023) · Advances in neurotoxicology · doi:10.1016/bs.ant.2023.01.001

Detection And Characterisation Of Chemical Induced Mitochondrial Perturbations utilising human in vitro models

Carta, G. (2023) · doi:10.5463/thesis.555

Papel da mitofusina 2 e da dinâmica mitocondrial na diferenciação e função de osteoclastos

Venturini, L. G. R. (2023) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2023.tde-08022024-153620

Additional file 2 of Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells

Du, R., Sullivan, D. K., Azizian, N. G., Liu, Y., & Li, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14175865

Tissue-specific atlas of trans-models for gene regulation elucidates complex regulation patterns

D’Agostino, R. D., & Gottlieb, A. (2024) · BMC Genomics · doi:10.1186/s12864-024-10317-y

Metabolic adaption of epithelial cells in asthma: a window to the initiation of carcinogenesis?

Dymond, T. (2024) · doi:10.37349/eaa.2024.00043 · Cited by 1

Reactive Oxygen Species (ROS), Mitochondrial Dynamics & Functionality in Parkinson\'s Disease - A Brief Communication

Chakraborty, P., & Mukherjee, D. (2021) · Journal of Applied Biochemistry & Laboratory Medicine · doi:10.5005/jablm-11031-02102

Dual diagnosis: unravelling the complexity of mitochondrial respiratory chain disorder and familial hypercholesterolemia in early childhood

Phadke, A. K., Kumble, A., KHAN, S., & Raikar, P. S. (2025) · International Journal of Research in Medical Sciences · doi:10.18203/2320-6012.ijrms20250273

The hallmarks and existing therapies of Parkinson’s Disease

Jin, Q. (2024) · Highlights in Science Engineering and Technology · doi:10.54097/9ftt5c50

NDUFS1 promotes malignant breast cancer behaviors through activation of mitochondrial metabolism and PROX1/c-Myc signalingPreprint

Wang, Y., Chen, P., Nguyen, H. D. H., Tseng, C., Chen, Y.-K., Hu, S. C., Lo, S. J., Hou, M., & Yuan, S. F. (2025) · Research Square · doi:10.21203/rs.3.rs-5968936/v1

Life History-Dependent Brain Transcriptomic Signatures in Nothobranchids: Insights into Aging, Neurogenesis, and Life History Evolution

Leow, C. J., & Piller, K. R. (2025) · Integrative Organismal Biology · doi:10.1093/iob/obaf016

Induction of hypoxic response despite normoxic conditions is associated with vascular mitochondrial dysfunction in diet induced metabolic syndromePreprint

Madan, E., Jain, V., & Singh, V. P. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.05.652328

Pneumococcal H 2 O 2 Reshapes Mitochondrial Function and Reprograms Host Cell MetabolismPreprint

Scasny, A., Alibayov, B., Hoang, N., Vidal, A. G. J., Takeshita, K., Bautista, C., Bengtén, E., Baez, A., Li, W., Hosler, J. P., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.22.655446

The genetic origin of fetal growth restriction and mitochondrial complex I dysregulationPreprint

Fisher, J. J., Wang, C. A., Botha, V. B., Acharya, S., Murray, H. C., Schjenken, J. E., Pennell, C. E., & Smith, R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.19.660636

Electron transport chain complex I and mitochondrial fusion regulate ROS for differentiation in Drosophila neural stem cellsPreprint

Verma, R. K., Bhingare, A., Dubal, D., & Rikhy, R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.22.666060

Sigma-1 receptor promotes glycolysis in neuronal systems by suppressing GRIM19

Couly, S., Yasui, Y., Grammatikakis, I., Kimura, Y., Hinkle, J. J., Gomez, J. L., Wu, H.-E., Paritosh, G., Lal, A., Michaelides, M., et al. (2026) · iScience · doi:10.1016/j.isci.2026.116092

Extruded Spirulina and enzyme supplementation modulate hepatic proteome and metabolism in broilers

Spínola, M. P., Maslov, D. R., Rubić, I., Costa, M. M., Mrljak, V., Lordelo, M. M., de Almeida, A. M., & Prates, J. A. M. (2025) · Research in Veterinary Science · doi:10.1016/j.rvsc.2025.105824

The Loss of Complex I in Renal Oncocytoma Is Associated with Defective Mitophagy Due to Lysosomal Dysfunction

Lin, L., Patel, N., Fernández-del-Río, L., Benica, C., Wilde, B. R., Christodoulou, E., Ohtake, S., Jeong, A., Kaba, A., Matulionis, N., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157654

Extruded Limnospira platensis with enzyme supplementation shifts the broiler muscle proteome toward enhanced energy metabolism pathways

Spínola, M. P., Maslov, D. R., Rubić, I., Costa, M. M., Mrljak, V., Lordelo, M. M., de Almeida, A. M., & Prates, J. A. M. (2025) · Journal of Proteomics · doi:10.1016/j.jprot.2025.105541

IT TAKES TWO TO TANGO: potential novel therapies for autosomal dominant optic atrophy

Sampige, R. R., Seaborn, L. E. A., Pluenneke, M., Jyothi, A., Saland, S., Chinedu-Obi, C. M., Keehn, C. C., & Lee, A. G. (2025) · Frontiers in Ophthalmology · doi:10.3389/fopht.2025.1688232

Mitochondrial integrated stress response activation creates a therapeutic vulnerability to MCL-1 inhibition in acute myeloid leukemia

Brakefield, L., Budhraja, A., Hall, P. A., Brewington, D., Moore, J., Lott, J., Ni, Y., Voronin, D., Grant-Chapman, O., Mukiza, T. O., et al. (2026) · Cell Death and Disease · doi:10.1038/s41419-026-09037-w

Additional file 3 of Mitochondrial defects in the respiratory complex I contribute to impaired translational initiation via ROS and energy homeostasis in SMA motor neurons

Thelen, M. P., Wirth, B., & Kye, M. J. (2020) · Figshare · doi:10.6084/m9.figshare.13481043

Additional file 1 of Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells

Du, R., Sullivan, D. K., Azizian, N. G., Liu, Y., & Li, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14175862

Additional file 4 of PAUSE: principled feature attribution for unsupervised gene expression analysis

Janizek, J. D., Spiro, A. E., Çelik, S., Blue, B. W., Russell, J. C., Lee, T.-I., Kaeberlin, M., & Lee, S. (2024) · Figshare · doi:10.6084/m9.figshare.26583564

Additional file 2 of PAUSE: principled feature attribution for unsupervised gene expression analysis

Janizek, J. D., Spiro, A. E., Çelik, S., Blue, B. W., Russell, J. C., Lee, T.-I., Kaeberlin, M., & Lee, S. (2024) · Figshare · doi:10.6084/m9.figshare.26583558

Additional file 1 of Tissue-specific atlas of trans-models for gene regulation elucidates complex regulation patterns

D’Agostino, R. D., & Gottlieb, A. (2024) · Figshare · doi:10.6084/m9.figshare.25632975

Additional file 3 of PAUSE: principled feature attribution for unsupervised gene expression analysis

Janizek, J. D., Spiro, A. E., Çelik, S., Blue, B. W., Russell, J. C., Lee, T.-I., Kaeberlin, M., & Lee, S. (2024) · Figshare · doi:10.6084/m9.figshare.26583561

Additional file 1 of Mitochondrial defects in the respiratory complex I contribute to impaired translational initiation via ROS and energy homeostasis in SMA motor neurons

Thelen, M. P., Wirth, B., & Kye, M. J. (2020) · Figshare · doi:10.6084/m9.figshare.13481037

Additional file 1 of Regulation of metastatic potential by drug repurposing and mitochondrial targeting in colorectal cancer cells

Mathur, S., Srivastava, P., Srivastava, A., Rai, N. K., Abbas, S., Kumar, A., Tiwari, M., & Sharma, L. K. (2024) · Figshare · doi:10.6084/m9.figshare.25374743

Structure of Respiratory Complex I: “Minimal” Bacterial and “De luxe” Mammalian Versions

Sazanov, L. A. (2017) · Royal Society of Chemistry eBooks · doi:10.1039/9781788010405-00025 · Cited by 3

Complex I of mitochondrial respiratory chain a its disorders.

Rodinová, M. (2010) · Digital Repository (National Repository of Grey Literature)

Structure and function of mitochondrial complex I

Wirth, C., Brandt, U., Hunte, C., & Zickermann, V. (2016) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2016.02.013 · Cited by 346

Gaining mass: the structure of respiratory complex I—from bacterial towards mitochondrial versions

Letts, J. A., & Sazanov, L. A. (2015) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2015.08.008 · Cited by 39

Mitochondrial complex I: structure, function and pathology

Janssen, R. J. R. J., Nijtmans, L. G., Heuvel, L. P. V. D., & Smeitink, J. A. M. (2006) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-006-0362-4 · Cited by 276