Cited by 426Essential Oils and Antimicrobial ActivityAntimicrobial agents and applicationsAntibiotic Resistance in Bacteria

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Essential Oils, A New Horizon in Combating Bacterial Antibiotic Resistance

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Yap, Polly Soo Xi, Yiap, Beow Chin, Ping, Hu Cai, Lim, Swee Hua Erin·2014·The Open Microbiology Journal

DOI 10.2174/1874285801408010006PMC PMC3950955

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Abstract

For many years, the battle between humans and the multitudes of infection and disease causing pathogens continues. Emerging at the battlefield as some of the most significant challenges to human health are bacterial resistance and its rapid rise. These have become a major concern in global public health invigorating the need for new antimicrobial compounds. A rational approach to deal with antibiotic resistance problems requires detailed knowledge of the different biological and non-biological factors that affect the rate and extent of resistance development. Combination therapy combining conventional antibiotics and essential oils is currently blooming and represents a potential area for future investigations. This new generation of phytopharmaceuticals may shed light on the development of new pharmacological regimes in combating antibiotic resistance. This review consolidated and described the observed synergistic outcome between essential oils and antibiotics, and highlighted the possibilities of essential oils as the potential resistance modifying agent.

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Authors: Yap, P. S. X., Yiap, B. C., Ping, H. C., & Lim, S. H. E.
Affiliations: IMU University (MY)
Corresponding author: Lim, Swee Hua Erin
ORCID: Yap, Polly Soo Xi
Lim, Swee Hua Erin
Venue: The Open Microbiology Journal
Publisher: Bentham Science Publishers Ltd.
Published: 2014-02-07
Volume: 8
Issue: 1
Pages: 6-14
ISSN: 1874-2858 (ISSN-L)
DOI: 10.2174/1874285801408010006
PMC: PMC3950955
OpenAlex: W2133763626
Cited by: 426
References: 88
Citations by year: 2026: 20 · 2025: 40 · 2024: 50 · 2023: 39 · 2022: 48 · 2021: 51 · 2020: 43 · 2019: 43 · 2018: 31 · 2017: 29 · 2016: 16 · 2015: 12 · 2014: 3
FWCI: 28.67
Type: journal article
Language: en
Open access: diamond
doi.org
Licence: cc-by
creativecommons.org/licenses/by-nc/3.0/ (unspecified)
Locations: The Open Microbiology Journal (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
PubMed Central (publishedVersion, cc-by-nc)
PubMed (publishedVersion)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antimicrobial agents and applications
Health Sciences › Medicine › Microbiology (medical) › Antibiotic Resistance in Bacteria
Keywords: essential oils, antibiotic resistance, bacterial resistance, antimicrobial synergy, combination therapy, herbal medicine, resistance-modifying agents, antimicrobial agents

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Essential Oils, A New Horizon in Combating Bacterial Antibiotic Resistance

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