Cited by 211Digital Mental Health InterventionsEthics and Social Impacts of AIArtificial Intelligence in Healthcare and Education

Exploring the Ethical Challenges of Conversational AI in Mental Health Care: Scoping Review

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Rahsepar Meadi, Mehrdad, Sillekens, Tomas, Metselaar, Suzanne, van Balkom, Anton, Bernstein, Justin, Batelaan, Neeltje·2025·JMIR Mental Health

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Abstract

Background: Conversational artificial intelligence (CAI) is emerging as a promising digital technology for mental health care. CAI apps, such as psychotherapeutic chatbots, are available in app stores, but their use raises ethical concerns. Objective: We aimed to provide a comprehensive overview of ethical considerations surrounding CAI as a therapist for individuals with mental health issues. Methods: We conducted a systematic search across PubMed, Embase, APA PsycINFO, Web of Science, Scopus, the Philosopher’s Index, and ACM Digital Library databases. Our search comprised 3 elements: embodied artificial intelligence, ethics, and mental health. We defined CAI as a conversational agent that interacts with a person and uses artificial intelligence to formulate output. We included articles discussing the ethical challenges of CAI functioning in the role of a therapist for individuals with mental health issues. We added additional articles through snowball searching. We included articles in English or Dutch. All types of articles were considered except abstracts of symposia. Screening for eligibility was done by 2 independent researchers (MRM and TS or AvB). An initial charting form was created based on the expected considerations and revised and complemented during the charting process. The ethical challenges were divided into themes. When a concern occurred in more than 2 articles, we identified it as a distinct theme. Results: We included 101 articles, of which 95% (n=96) were published in 2018 or later. Most were reviews (n=22, 21.8%) followed by commentaries (n=17, 16.8%). The following 10 themes were distinguished: (1) safety and harm (discussed in 52/101, 51.5% of articles); the most common topics within this theme were suicidality and crisis management, harmful or wrong suggestions, and the risk of dependency on CAI; (2) explicability, transparency, and trust (n=26, 25.7%), including topics such as the effects of “black box” algorithms on trust; (3) responsibility and accountability (n=31, 30.7%); (4) empathy and humanness (n=29, 28.7%); (5) justice (n=41, 40.6%), including themes such as health inequalities due to differences in digital literacy; (6) anthropomorphization and deception (n=24, 23.8%); (7) autonomy (n=12, 11.9%); (8) effectiveness (n=38, 37.6%); (9) privacy and confidentiality (n=62, 61.4%); and (10) concerns for health care workers’ jobs (n=16, 15.8%). Other themes were discussed in 9.9% (n=10) of the identified articles. Conclusions: Our scoping review has comprehensively covered ethical aspects of CAI in mental health care. While certain themes remain underexplored and stakeholders’ perspectives are insufficiently represented, this study highlights critical areas for further research. These include evaluating the risks and benefits of CAI in comparison to human therapists, determining its appropriate roles in therapeutic contexts and its impact on care access, and addressing accountability. Addressing these gaps can inform normative analysis and guide the development of ethical guidelines for responsible CAI use in mental health care.

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  • Existing scoping reviews focus on ethical challenges of LLM-CBs as psychotherapists without scoping harms for mental health specifically, or scope mass media narratives.

    “existing scoping reviews focus on ethical challenges of LLM-CBs as psychotherapists (e.g., focusing on consent, autonomy, and responsibility) without scoping harms for mental health specifically33, or scope mass media narratives in the shape of rapid scoping34.”

    From A scoping review on the mental health harms of LLM-based chatbots (2026) · cites this paper as [33]

    The paper does review ethical challenges of conversational AI used as therapists, but the Results (Ethical Themes; page unavailable) explicitly include a “Safety and Harm” theme covering 52 of 101 articles. That section examines mental-health-specific concerns, including responses to suicidality and harmful advice for people with eating disorders, contrary to the claim that it does not scope such harms. The separate mass-media-narratives clause is attached to citation 34, not this source. (LLM, conf=0.88)

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  • Systematic and scoping reviews show that LLM-CB risks (e.g., consistencies, hallucinations, ethical risks) may outweigh potential benefits.

    “Systematic and scoping reviews show that LLM-CB risks (e.g., consistencies, hallucinations, ethical risks) may outweigh potential benefits33,76,77.”

    From A scoping review on the mental health harms of LLM-based chatbots (2026) · cites this paper as [33]

    The Results (Ethical Themes; page unavailable) identify harmful or hallucinatory suggestions, and the Discussion (Principal Findings; page unavailable) says such concerns could undermine CAI’s potential benefits. But the Discussion (Suggestions for Future Research) calls for evaluating risks against benefits to determine whether use is justifiable; the review does not conclude that risks may outweigh benefits. (LLM, conf=0.86)

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Cited by

Sorted by citations

Authors
Rahsepar Meadi, M., Sillekens, T., Metselaar, S., van Balkom, A., Bernstein, J., & Batelaan, N.
Affiliations
  • GGz centraal (NL)
  • Vrije Universiteit Amsterdam (NL)
  • Amsterdam Public Health (NL)
Venue
JMIR Mental Health
Published
2025-02-21
Volume
12
Pages
e60432
ISSN
2368-7959 (ISSN-L)
OpenAlex
W4407833429
Cited by
211
References
37
Citations by year
2026: 164 · 2025: 47
FWCI
24.56
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • JMIR Mental Health (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (publishedVersion, other-oa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • VU Research Portal (submittedVersion, cc-by)
Topics
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
  • Social Sciences › Safety Research › Ethics and Social Impacts of AI
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
Keywords
conversational AI, chatbots, mental health services, AI ethics, embodied AI, suicidality, trust and transparency, accountability, empathy, justice, digital literacy, anthropomorphism, deception, autonomy, informed consent, mental health apps, human-AI interaction, digital divide, health disparities, crisis management, harm reduction
MeSH terms
Artificial Intelligence, Mental Disorders, Communication, Humans, Mental Health Services

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