Cited by 38Explainable Artificial Intelligence (XAI)Digital Mental Health InterventionsArtificial Intelligence in Healthcare and Education

A review of the explainability and safety of conversational agents for mental health to identify avenues for improvement

Open access
Sarkar, Surjodeep, Gaur, Manas, Chen, Lujie Karen, Garg, Muskan, Srivastava, Biplav·2023·Frontiers in Artificial Intelligence

Abstract

Virtual Mental Health Assistants (VMHAs) continuously evolve to support the overloaded global healthcare system, which receives approximately 60 million primary care visits and 6 million emergency room visits annually. These systems, developed by clinical psychologists, psychiatrists, and AI researchers, are designed to aid in Cognitive Behavioral Therapy (CBT). The main focus of VMHAs is to provide relevant information to mental health professionals (MHPs) and engage in meaningful conversations to support individuals with mental health conditions. However, certain gaps prevent VMHAs from fully delivering on their promise during active communications. One of the gaps is their inability to explain their decisions to patients and MHPs, making conversations less trustworthy. Additionally, VMHAs can be vulnerable in providing unsafe responses to patient queries, further undermining their reliability. In this review, we assess the current state of VMHAs on the grounds of user-level explainability and safety, a set of desired properties for the broader adoption of VMHAs. This includes the examination of ChatGPT, a conversation agent developed on AI-driven models: GPT3.5 and GPT-4, that has been proposed for use in providing mental health services. By harnessing the collaborative and impactful contributions of AI, natural language processing, and the mental health professionals (MHPs) community, the review identifies opportunities for technological progress in VMHAs to ensure their capabilities include explainable and safe behaviors. It also emphasizes the importance of measures to guarantee that these advancements align with the promise of fostering trustworthy conversations.

AI snapshot

Written from the paper’s full text.

TL;DR

This review assesses explainability and safety in virtual mental health assistants (VMHAs), including ChatGPT, Woebot, Wysa, Limbic, and ALLEVIATE, and argues that current systems often lack user-level explainability and clinically grounded safe responses. It proposes knowledge-infused learning with clinical guidelines such as PHQ-9 and GAD-7, plus new qualitative and knowledge-infusion evaluation metrics, to improve trustworthiness.

Key findings

  • The review reports that existing VMHAs such as Woebot, Wysa, and ChatGPT generated assumptive questions or responses with no association to a clinical reference or clinical support in a real-world unemployment-related query.
  • It cites evidence that safety lexicons from PHQ-9 and GAD-7 produced an 85% improvement in safety across sequence-to-sequence and attention-based language models, with explainability showing a 23% uptake in terms of safety across the same models.
  • Approximately 70% of attendees at the inaugural safety for conversational AI workshop doubted the ability of present-day conversational systems relying on language models to produce safe responses.
  • Table 2 contrasts existing VMHAs with a desired system: Woebot, Wysa, Limbic, and ALLEVIATE mostly lack user-level explainability, while the desired system is marked for screening, triaging, motivational interviewing, safety, user-level explainability, and qualitative metrics of harmlessness, adherence, and transparency.

Methods

  • Narrative review organized around five research questions on defining explainability and safety in VMHAs, assessing current capabilities and limitations, analyzing AI challenges, exploring desired functionalities, and identifying evaluation changes.
  • Evidence includes examination of ChatGPT/GPT-3.5/GPT-4, Woebot, Wysa, Limbic, and ALLEVIATE, conversational datasets, and a high-level analysis of publicly available user reviews on forums such as WebMD, AskaPatient, MedicineNet, and Reddit; Table 2 notes a survey of 40 participants at Prisma Health for Woebot, Wysa, and Alleviate.
  • Main analysis is qualitative synthesis and taxonomy development, proposing qualitative metrics (adherence, harmlessness, transparency) and knowledge-infusion metrics (safety, logical coherence, semantic relations).

Limitations

  • The paper states that there currently exists no mental health-specific dataset or established method rooted in clinical principles for refining LLMs to ensure safety, and that rule-based and data-driven safety methods are limited by size and context.
  • The paper states that VMHAs may not fully understand behavioral and emotional instability, self-harm tendencies, and the user’s underlying psychological state.
  • Evident from the text: as a narrative review, no systematic search strategy, inclusion/exclusion criteria, or risk-of-bias assessment is reported, and the proposed evaluation metrics are not empirically validated in the paper.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.3389/frai.2023.1229805

Cites

122 of 122 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Claims the paper makes

0 of 33 cited sources checked · 0 supported · 0 flagged

  • Findingown data

    GPT 3.5 provides user-level explainability when prompted with clinically-relevant words and keyphrases such as pregnancy, morning sickness, vomiting, nausea, and anxiety caused by tranquilizers during pregnancy.

    “Figure 4 GPT 3.5 provides user-level explainability when prompted with clinically-relevant words and keyphrases such as pregnancy, morning sickness, vomiting, nausea, and anxiety caused by tranquilizers during pregnancy.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: The clinical knowledge bases UMLS and RxNorm contain accurate and sufficient relationships between pregnancy, symptoms, and causes for generating symbolic questions.
  • Findingnone given

    Current datasets typically have a foundation in psychology but are crowd-sourced rather than explicitly derived from clinically grounded guidelines of psychiatrists.

    “The current datasets typically have a foundation in psychology but are crowd-sourced rather than explicitly derived from clinically grounded guidelines of psychiatrists.”
    Quote in the paperNot a substantial claim
  • Findingown data

    Without specific keyphrases, GPT 3.5 may produce incorrect inferences.

    “Without these specific keyphrases, GPT 3.5 may produce incorrect inferences [shown in (b)].”
    Quote in the paperSubstantial claim
  • Findingnone given

    VMHAs generate incoherent and unsafe responses when a user tries to seek a response for clinically relevant questions or vice-versa.

    “VMHAs (as exemplified in Figures 2, 3) generate incoherent and unsafe responses when a user tries to seek a response for clinically relevant questions or vice-versa.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The examples in Figures 2, 3, and 4 are representative of how VMHAs generally behave.
  • Findingnone given

    VMHAs may not fully understand issues related to behavioral and emotional instability, self-harm tendencies, and the user's underlying psychological state.

    “our observations suggest that VMHAs may not fully understand issues related to behavioral and emotional instability, self-harm tendencies, and the user's underlying psychological state.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The examples in Figures 2, 3, and 4 are representative of how VMHAs generally behave.
  • May combine two claims. 23
  • Classified as probably not a substantial claim. 31
  • The quote only partly states this claim. 1
  • May combine two claims.

    Findingcitation

    Existing VMHAs Woebot, Wysa, and ChatGPT initiated responsive conversation without focusing on context, producing assumptive questions and responses with no association with a clinical reference or clinical support.

    “As a result, we found assumptive questions (e.g., anxiety) and responses from Wysa, Woebot, and ChatGPT with no association with a clinical reference or clinical support.”
    Quote in the paperSubstantial claim0 of 3 sources checked
    • cites Fitzpatrick et al., 2017 source

      Not checked in the free run.

    • cites Inkster et al., 2018 source

      Not checked in the free run.

    • cites Leiter et al., 2023

      Not checked in the free run.

  • May combine two claims.

    Findingreasoning

    Both Limbic and ALLEVIATE incorporate safety measures, but they do so with a nuanced distinction in their implementation approaches.

    “Table 2 illustrates that both Limbic and ALLEVIATE incorporate safety measures, but they do so with a nuanced distinction in their implementation approaches.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: The survey of 40 participants at Prisma Health provides a valid basis for the high-level analysis of Woebot, Wysa, and Alleviate.
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Findingown data

    The next word prediction strategy of the generative AI within the VMHA suggesting that "the fact that you are using tranquilizer medication is a step in the right direction, but it is essential to address the root cause of your anxiety as well" is a harmful statement, because tranquilizers cause anxiety during pregnancy.

    “The next word prediction strategy of the generative AI within the VMHA suggests that “the fact that you are using tranquilizer medication is a step in the right direction, but it is essential to address the root cause of your anxiety as well”. is a harmful statement, because tranquilizers cause anxiety during pregnancy (as shown Figure 4).”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: The examples in Figures 2, 3, and 4 are representative of how VMHAs generally behave.
    • Rests on an assumption: The clinical knowledge bases UMLS and RxNorm contain accurate and sufficient relationships between pregnancy, symptoms, and causes for generating symbolic questions.
  • Classified as probably not a substantial claim.

    Findingreasoning

    There was not a pursuit of grounding datasets with clinical knowledge and clinical practice guidelines and use in training VMHAs.

    “As such, there was not a pursuit of grounding datasets with clinical knowledge and clinical practice guidelines and use in training VMHAs.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The examples in Figures 2, 3, and 4 are representative of how VMHAs generally behave.
  • May combine two claims.

    Findingnone given

    Currently, there exists no mental health-specific datasets or established method rooted in clinical principles for refining LLMs to ensure their safety.

    “Nonetheless, currently, there exists no mental health-specific datasets or established method rooted in clinical principles for refining LLMs to ensure their safety.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S2 (checkable).

    Findingnone given

    VMHAs remain distant from translational research.

    “However, VMHAs remain distant from such translational research.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: The examples in Figures 2, 3, and 4 are representative of how VMHAs generally behave.
  • Probably not a substantial claim: may not pass S4 (based).

    Interpretationnone given

    VMHAs' inability to explain their decisions to patients and MHPs makes conversations less trustworthy.

    “One of the gaps is their inability to explain their decisions to patients and MHPs, making conversations less trustworthy.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S4 (based). May combine two claims.

    Interpretationnone given

    VMHAs can be vulnerable to providing unsafe responses to patient queries, which undermines their reliability.

    “Additionally, VMHAs can be vulnerable in providing unsafe responses to patient queries, further undermining their reliability.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisereasoning

    Lexicons in mental health resolve ambiguities in human language.

    “Lexicons in mental health resolve ambiguities in human language.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Interpretationreasoning

    Clinical practice guidelines such as PHQ-9 enable VMHAs to exercise control over content generation, preventing the generation of false or unsafe information.

    “Such guidelines act as standards that enable VMHAs to exercise control over content generation, preventing generating false or unsafe information.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: Clinical specification questions are safe and medically adapted.
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisenone given

    KIL involves injecting external knowledge into the learning process to enhance the AI model's performance and achieve user-level explainability and safety.

    “The concept of KIL involves injecting external knowledge, such as domain-specific rules, ontologies, or expert knowledge, into the learning process to enhance the AI model's performance and achieve USEx and safety.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Interpretationreasoning

    Ensuring diversity in generation poses a natural challenge in open-domain conversations, but it becomes an unavoidable aspect in domain-specific conversations for VMHAs.

    “Ensuring diversity in generation poses a natural challenge in open-domain conversations, but it becomes an unavoidable aspect in domain-specific conversations for VMHAs.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    Clinical specifications include questionnaires such as PHQ-9, C-SSRS, and GAD-7, and provide a sequence of questions clinicians follow to interview individuals with mental health conditions.

    “Clinical specifications1 include questionnaires such as PHQ-9 (depression), Columbia Suicide Severity Rating Scale [C-SSRS; suicide (Posner et al., 2008)], Generalized Anxiety Disorder (GAD-7) (Coda-Forno et al., 2023). It provides a sequence of questions clinicians follow to interview individuals with mental health conditions.”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites Posner et al., 2008

      Not checked in the free run.

    • cites Coda-Forno et al., 2023

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S2 (checkable).

    Interpretationreasoning

    To ensure that VMHAs are both safe and understandable, datasets need to be semantically enhanced with clinically grounded knowledge or clinical practice guidelines.

    “To ensure that VMHAs are both safe and understandable, these datasets need to be semantically enhanced with clinically grounded knowledge [e.g., MedChatbot (Kazi et al., 2012)] or clinical practice guidelines [e.g., Patient Health Questionnaire (PHQ-9) (Kroenke et al., 2001)].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites Kazi et al., 2012

      Not checked in the free run.

    • cites Kroenke et al., 2001 source

      Not checked in the free run.

    • Rests on an assumption: Clinical specification questions are safe and medically adapted.
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Interpretationcitation

    By incorporating such knowledge, the decision-making ability of AI can be enhanced and better equipped to generate explanations that are more comprehensible to humans.

    “By incorporating such knowledge, the decision-making ability of AI can be enhanced and better equipped to generate explanations that are more comprehensible to humans (Joyce et al., 2023).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Joyce et al., 2023

      Not checked in the free run.

    • Rests on an assumption: Clinical specification questions are safe and medically adapted.
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    Woebot is an Automated Coach designed to provide a coach-like experience without human intervention, promoting good thinking hygiene through lessons, exercises, and videos rooted in CBT.

    “Woebot is an Automated Coach designed to provide a coach-like experience without human intervention, promoting good thinking hygiene through lessons, exercises, and videos rooted in Cognitive Behavioral Therapy (CBT) (Fitzpatrick et al., 2017; Grigoruta, 2018).”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites Fitzpatrick et al., 2017 source

      Not checked in the free run.

    • cites Grigoruta, 2018

      Not checked in the free run.

    • Rests on an assumption: The survey of 40 participants at Prisma Health provides a valid basis for the high-level analysis of Woebot, Wysa, and Alleviate.
  • Probably not a substantial claim: may not pass S2 (checkable).

    Interpretationreasoning

    The above analysis supports the critical need for an explainable approach to the decision-making mechanism of VMHAs.

    “The above analysis supports the critical need for an explainable approach to the decision-making mechanism of VMHAs.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Approximately 70% of workshop attendees doubted the ability of present-day conversational systems that rely on language models to produce safe responses.

    “Approximately 70% of workshop attendees doubted the ability of present-day conversational systems that rely on language models to produce safe responses (Dinan, 2020).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Dinan, 2020

      Not checked in the free run.

  • Classified as probably not a substantial claim.

    Interpretationreasoning

    The risk of user disengagement arises if the chatbot asks redundant questions or provides repetitive responses.

    “The risk of user disengagement arises if the chatbot asks redundant questions or provides repetitive responses.”
    Quote in the paperSubstantial claim
  • Classified as probably not a substantial claim.

    Premisecitation

    The absence of any link to a factual knowledge source that can help LLMs reason on their generation introduces the black box effect.

    “The absence of any link to a factual knowledge source that can help LLMs reason on their generation introduce what is known as the “black box” effect (Rudin, 2019).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Rudin, 2019 source

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    Wysa uses a CBT conversational agent to engage in empathetic and therapeutic conversations and activities, aiming to help users with various mental health problems.

    “Wysa uses a CBT conversational agent to engage in empathetic and therapeutic conversations and activities, aiming to help users with various mental health problems (Inkster et al., 2018).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Inkster et al., 2018 source

      Not checked in the free run.

    • Rests on an assumption: The survey of 40 participants at Prisma Health provides a valid basis for the high-level analysis of Woebot, Wysa, and Alleviate.
  • Classified as probably not a substantial claim. May combine two claims. The quote only partly states this claim.

    Interpretationreasoning

    As a conversation unfolds, it becomes necessary to continually update the knowledge graph to ensure safety, because patients may experience varying levels of mental health conditions due to comorbidities and evolving severity, and contextual dynamics may shift.

    “As the conversation unfolds, it becomes necessary to continually update the KG to ensure safety, which holds particular significance in VMHA.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    In Limbic, patient safety is considered to be a spontaneous assessment of the severity of the mental health condition of the user (a classification problem), and it prioritizes patients seeking in-person clinical care.

    “In Limbic, patient safety is considered to be a spontaneous assessment of the severity of the mental health condition of the user (a classification problem). It prioritizes patients seeking in-person clinical care (Sohail, 2023).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Sohail, 2023

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    People are particularly forthcoming about their mental health problems while interacting with conversational agents, which may increase the danger of agreeing with user utterances that imply self-harm.

    “People have been proven to be particularly forthcoming about their mental health problems while interacting with conversational agents, which may increase the danger of “agreeing with those user utterances that imply self-harm”.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Dinan et al., 2022 source

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).

    Interpretationreasoning

    In mental health, clinical specifications can serve as a substitute for rules to confirm that the AI model is functioning within safe limits.

    “In mental health, clinical specifications can serve as a substitute for rules to confirm that the AI model is functioning within safe limits.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: Clinical specification questions are safe and medically adapted.
  • May combine two claims.

    Premisecitation

    The component can generate false information or inference upon personally identifiable information, thus sacrificing user privacy.

    “The component can generate false information or inference upon personally identifiable information, thus sacrificing user privacy (Coghlan et al., 2023).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Coghlan et al., 2023

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Interpretationnone given

    Adherence to guidelines helps VMHA maintain context and ensure safe conversation.

    “Adherence to guidelines helps VMHA maintain context and ensure safe conversation.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    Most traditional quantitative metrics are reference-based, which are limited in availability and make it very difficult to ensure the quality of the human-written references.

    “In addition, most of these traditional quantitative metrics are reference-based, which are limited in availability and make it very difficult to ensure the quality of the human-written references (Bao et al., 2022).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Bao et al., 2022

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Interpretationreasoning

    The question generation and response generation in ALLEVIATE are bound by the subgraph and information in the backend knowledge bases, thus ensuring accountable, transparent, and safe conversation.

    “The question generation and response generation in ALLEVIATE are bound by the subgraph and information in the backend knowledge bases, thus ensuring accountable, transparent, and safe conversation.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: The survey of 40 participants at Prisma Health provides a valid basis for the high-level analysis of Woebot, Wysa, and Alleviate.
  • May combine two claims.

    Premisecitation

    The conversational agents generate harmful, unsafe, and sometimes incoherent information, which are the negative effects of generative AI.

    “The conversational agents generate harmful, unsafe, and sometimes incoherent information, which are the negative effects of generative AI (Welbl et al., 2021).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Welbl et al., 2021

      Not checked in the free run.

    • Rests on an assumption: The examples in Figures 2, 3, and 4 are representative of how VMHAs generally behave.
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    People perceive the quality of a service based on the price paid for it and the word of mouth buzz around it.

    “A well-understood result in marketing is that people perceive the quality of a service based on the price paid for it and the word of mouth buzz around it (Liu and Lee, 2016).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Liu and Lee, 2016

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).

    Premisenone given

    Obtaining training data from real conversations can be challenging due to privacy concerns.

    “While obtaining training data from real conversations can be challenging due to privacy concerns, some approaches can help address these issues and still provide valuable and useful outputs.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).

    Interpretationreasoning

    Transparency can be achieved by either augmenting or incorporating external knowledge.

    “Transparency can be achieved by either augmenting or incorporating external knowledge.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Interpretationreasoning

    In contrast to the in-person sessions, the conversational agents miss the personalized and contextual information from non-verbal communication hindering the efficacy of VMHAs.

    “In contrast to the in-person sessions (leveraged on both verbal and non-verbal communication), the conversational agents miss the personalized and contextual information from non-verbal communication hindering the efficacy of VMHAs.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: The examples in Figures 2, 3, and 4 are representative of how VMHAs generally behave.
  • Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).

    Interpretationnone given

    Creating a realistic conversational experience for VMHAs is important for user acceptance.

    “Creating a realistic conversational experience for VMHAs is important for user acceptance.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: The examples in Figures 2, 3, and 4 are representative of how VMHAs generally behave.
  • May combine two claims.

    Interpretationreasoning

    Despite the efforts, VMHA is still susceptible to generating harmful and untrustworthy content, as these methods are limited by size and context.

    “Despite the efforts, VMHA is still susceptible to generating harmful and untrustworthy content, as these methods are limited by size and context.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: The examples in Figures 2, 3, and 4 are representative of how VMHAs generally behave.
  • Probably not a substantial claim: may not pass S2 (checkable), S4 (based).

    Interpretationreasoning

    Traditional metrics such as accuracy, precision, and recall may not be sufficient to capture the nuances of these complex requirements.

    “Traditional metrics such as accuracy, precision, and recall may not be sufficient to capture the nuances of these complex requirements.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    The lack of safe responses, DiG, and UsEx within VMHAs has drawn criticism and raised concerns about the impact on adherence.

    “Despite the AI community's considerable interest in evaluating health assistants' adherence to user needs (Davis et al., 2020), the lack of safe responses, DiG, and UsEx within VMHAs has drawn criticism and raised concerns about the impact on adherence.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Davis et al., 2020

      Not checked in the free run.

    • Rests on an assumption: The examples in Figures 2, 3, and 4 are representative of how VMHAs generally behave.
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    ALLEVIATE creates a subgraph from the user's utterances and chatbot questions during the conversation, constructed by actively querying UMLS for disorders and symptoms and Rx-NORM for medicine.

    “ALLEVIATE creates a subgraph from the user's utterances and chatbot questions during the conversation. This subgraph is constructed by actively querying two knowledge bases: UMLS, for disorders and symptoms and Rx-NORM for medicine (Liu et al., 2005).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Liu et al., 2005

      Not checked in the free run.

    • Rests on an assumption: The survey of 40 participants at Prisma Health provides a valid basis for the high-level analysis of Woebot, Wysa, and Alleviate.
  • Probably not a substantial claim: may not pass S2 (checkable), S4 (based).

    Interpretationnone given

    Knowledge in various human-curated knowledge bases (both online and offline) is more exhaustive in terms of context.

    “In contrast, knowledge in various human-curated knowledge bases (both online and offline) is more exhaustive in terms of context.”
    Quote in the paperNot a substantial claim
40 of 40
  • The paper relies on this without support.

    Fabrication and hallucination problems already exist in smaller language models and are even more pronounced in larger ones.

    “While these problems already exist in smaller language models, they are even more pronounced in larger ones.”
  • The paper relies on this without support.

    Clinical specification questions are safe and medically adapted.

    “Such questions are safe and medically adapted.”
  • The paper relies on this without support.

    The examples in Figures 2, 3, and 4 are representative of how VMHAs generally behave.

    “VMHAs (as exemplified in Figures 2, 3) generate incoherent and unsafe responses when a user tries to seek a response for clinically relevant questions or vice-versa.”
    “Without these specific keyphrases, GPT 3.5 may produce incorrect inferences [shown in (b)].”
  • The paper relies on this without support.

    The survey of 40 participants at Prisma Health provides a valid basis for the high-level analysis of Woebot, Wysa, and Alleviate.

    “For Woebot, Wysa, and Alleviate, a survey of 40 participants was carried out at Prisma Health.”
  • The paper relies on this without support.

    The clinical knowledge bases UMLS and RxNorm contain accurate and sufficient relationships between pregnancy, symptoms, and causes for generating symbolic questions.

    “In Figure 4(a), the process generates two symbolic questions based on the relationship between pregnancy, symptoms, and causes found in clinical knowledge sources UMLS and RxNorm.”
5 of 5

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • AI systems introduce novel stressors that are continuous, personally salient, and socially immersive, thereby functioning as 24-hour contextual stimuli capable of modulating arousal, perception, and belief formation.

    “These systems introduce novel stressors that are continuous, personally salient, and socially immersive, thereby functioning as 24-hour contextual stimuli capable of modulating arousal, perception, and belief formation [19].”

    From Delusional Experiences Emerging From AI Chatbot Interactions or “AI Psychosis” (2025) · cites this paper as [19]

    Section 5.1 (page unavailable) says Woebot and Wysa track mood changes throughout the day and warns that discussing certain topics could exacerbate a user's mental health condition. It does not characterize these systems as continuous, socially immersive stressors or 24-hour stimuli, or say they modulate arousal, perception, and belief formation. (LLM, conf=0.77)

    Experimental — accuracy not yet measured
  • Systematic and scoping reviews show that LLM-CB risks (e.g., consistencies, hallucinations, ethical risks) may outweigh potential benefits.

    “Systematic and scoping reviews show that LLM-CB risks (e.g., consistencies, hallucinations, ethical risks) may outweigh potential benefits33,76,77.”

    From A scoping review on the mental health harms of LLM-based chatbots (2026) · cites this paper as [77]

    Section 2.1 says the consequences of LLMs’ black-box behavior are more concerning than their utility, particularly in mental health. Sections 5 and 6.1 describe incoherent, hallucinated, and unsafe responses from virtual mental health assistants. The source supports the risk–benefit concern in that setting, but it does not identify itself as a systematic or scoping review or establish the claim for LLM chatbots generally. (LLM, conf=0.85)

    Experimental — accuracy not yet measured

Cites

Flagged first, then by citations

Research works printed but not linked: 11

  1. Bao, 2022, Docasref: A pilot empirical study on repurposing reference-based summary quality metrics reference-freely, arXiv [Preprint]. arXiv:2212.10013, 10.48550/arxiv.2212.1001 · DOI
  2. 2015, Mental Health Answers from Counselors
  3. DinanR. 1st Safety for Conversational AI Workshop | ACL Member Portal2020
  4. 2022, Deepmind Introduces 'Sparrow,' An Artificial Intelligence-Powered Chatbot Developed to Build Safer Machine Learning Systems
  5. Huang, 2015, Language Use in Teenage Crisis Intervention and the Immediate Outcome: A Machine Automated Analysis of Large Scale Text Data
  6. Hyman, 2008, Self-Disclosure and its Impact on Individuals Who Receive Mental Health Services (hhs pub. no. sma-08-4337)
  7. Kruzan, 2019, Self-Injury Support Online: Exploring Use of the Mobile Peer Support Application TalkLife
  8. Lee, 2021, Restatement and question generation for counsellor chatbot. In 1st Workshop on Natural Language Processing for Programming (NLP4Prog), 1
  9. Roy, 2023, Alleviate ChatBot
  10. Welivita, “Curating a large-scale motivational interviewing dataset using peer support forums,”, 3315
  11. Zhang, 2019, Conversation generation with concept

Cited by

Sorted by citations

Authors
Sarkar, S., Gaur, M., Chen, L. K., Garg, M., & Srivastava, B.
Affiliations
  • University of Maryland, Baltimore County (US)
  • Mayo Clinic (US)
  • University of South Carolina (US)
Corresponding author
Sarkar, Surjodeep
Venue
Frontiers in Artificial Intelligence
Published
2023-10-12
Volume
6
Pages
1229805-1229805
ISSN
2624-8212 (ISSN-L)
OpenAlex
W4387578765
Cited by
38
References
121
Citations by year
2026: 10 · 2025: 16 · 2024: 11 · 2023: 1
FWCI
0.80
Type
journal article
Language
en
Open access
Locations
  • Frontiers in Artificial Intelligence (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Maryland Shared Open Access Repository (USMAI Consortium) (submittedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Digital Repository at the University of Maryland (University of Maryland College Park) (cc-by)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Explainable Artificial Intelligence (XAI)
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
Keywords
chatbots, explainability, AI safety, ChatGPT, GPT-4, cognitive behavioral therapy, mental health professionals, trust in AI, large language models

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-09.

Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-09.

Statistics and arithmetic are recomputed, not judged.

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