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Cited by 1,063

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Acute Kidney Injury Associated with Cardiac Surgery

Rosner, Mitchell H., Okusa, Mark D.·2006·Clinical Journal of the American Society of Nephrology

Abstract

Acute renal failure (ARF) occurs in up to 30% of patients who undergo cardiac surgery, with dialysis being required in approximately 1% of all patients. The development of ARF is associated with substantial morbidity and mortality independent of all other factors. The pathogenesis of ARF involves multiple pathways. Hemodynamic, inflammatory, and nephrotoxic factors are involved and overlap each other in leading to kidney injury. Clinical studies have identified risk factors for ARF that can be used to determine effectively the risk for ARF in patients who undergo bypass surgery. These high-risk patients then can be targeted for renal protective strategies. Thus far, no single strategy has demonstrated conclusively its ability to prevent renal injury after bypass surgery. Several compounds such as atrial natriuretic peptide and N-acetylcysteine have shown promise, but large-scale trials are needed.

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Metadata

Authors
Rosner, M. H., & Okusa, M. D.
Venue
Clinical Journal of the American Society of Nephrology
Published
2006-01
Volume
1
Issue
1
Pages
19-32
ISSN
1555-9041 (ISSN-L)
OpenAlex
W2097155000
Cited by
1,063
References
5
FWCI
8.43
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Acute Kidney Injury Associated with Cardiac Surgery. https://app.cochat.ai/papers/10.2215/cjn.00240605
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Rosner, M. H., & Okusa, M. D. (2006). Acute Kidney Injury Associated with Cardiac Surgery. Clinical Journal of the American Society of Nephrology. https://doi.org/10.2215/cjn.00240605

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.