Perfluorinated Chemicals as Emerging Environmental Threats to Kidney Health: A Scoping Review

Perfluoroalkyl and polyfluoroalkyl substances in the environment: Terminology, classification, and origins

Buck, R. C., Franklin, J., Berger, U., Conder, J. M., Cousins, I. T., de Voogt, P., Jensen, A. A., Kannan, K., Mabury, S. A., & van Leeuwen, S. P. (2011) · Integrated Environmental Assessment and Management · doi:10.1002/ieam.258 · Cited by 4,641

Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers

Olsen, G. W., Burris, J. M., Ehresman, D. J., Froehlich, J. W., Seacat, A. M., Butenhoff, J. L., & Zobel, L. R. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10009 · Cited by 2,049

Detection of Poly- and Perfluoroalkyl Substances (PFASs) in U.S. Drinking Water Linked to Industrial Sites, Military Fire Training Areas, and Wastewater Treatment Plants

Hu, X. C., Andrews, D. Q., Lindstrom, A. B., Bruton, T. A., Schaider, L. A., Grandjean, P., Lohmann, R., Carignan, C. C., Blum, A., Balan, S. A., et al. (2016) · Environmental Science & Technology Letters · doi:10.1021/acs.estlett.6b00260 · Cited by 1,333

Polyfluoroalkyl Chemicals in the U.S. Population: Data from the National Health and Nutrition Examination Survey (NHANES) 2003-2004 and Comparisons with NHANES 1999–2000

Calafat, A. M., Wong, L.-Y., Kuklenyik, Z., Reidy, J. A., & Needham, L. L. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10598 · Cited by 1,247

Fluorinated alternatives to long-chain perfluoroalkyl carboxylic acids (PFCAs), perfluoroalkane sulfonic acids (PFSAs) and their potential precursors

Wang, Z., Cousins, I. T., Scheringer, M., & Hungerbühler, K. (2013) · Environment International · doi:10.1016/j.envint.2013.08.021 · Cited by 924

Perfluorooctanoic Acid (PFOA) Exposures and Incident Cancers among Adults Living Near a Chemical Plant

Barry, V., Winquist, A. G., & Steenland, K. (2013) · Environmental Health Perspectives · doi:10.1289/ehp.1306615 · Cited by 824

Accumulation of perfluoroalkyl substances in human tissues

Pérez, F., Nadal, M., Navarro-Ortega, A., Fàbrega, F., Domingo, J. L., Barceló, D., & Farré, M. (2013) · Environment International · doi:10.1016/j.envint.2013.06.004 · Cited by 730

Epidemiologic Evidence on the Health Effects of Perfluorooctanoic Acid (PFOA)

Steenland, K., Fletcher, T., & Savitz, D. A. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901827 · Cited by 660

Biomonitoring of Perfluoroalkyl Acids in Human Urine and Estimates of Biological Half-Life

Zhang, Y., Beesoon, S., Zhu, L., & Martin, J. W. (2013) · Environmental Science & Technology · doi:10.1021/es401905e · Cited by 530

The Organic Anion Transporter (OAT) Family: A Systems Biology Perspective

Nigám, S. K., Bush, K. T., Martovetsky, G., Ahn, S.-Y., Liu, H. C., Richard, E., Bhatnagar, V., & Wu, W. (2014) · Physiological Reviews · doi:10.1152/physrev.00025.2013 · Cited by 526

Thermal decomposition mechanism and kinetics of perfluorooctanoic acid (PFOA) and other perfluorinated carboxylic acids: a theoretical study

Khan, M. Y., Song, J., Narimani, M., & da Silva, G. F. (2022) · Environmental Science Processes & Impacts · doi:10.1039/d2em00259k · Cited by 26

Association of per- and polyfluoroalkyl substance exposure with metabolic syndrome and its components in adults and adolescents

Zheng, H., Yin, Z., Luo, X., Zhou, Y., Fei, Z., & Guo, Z. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-30317-x · Cited by 25

6:2 chlorinated polyfluoroalkyl ether sulfonate (F–53B) induced nephrotoxicity associated with oxidative stress, inflammation and fibrosis in mice

Wu, H., Feng, Y., Zhang, R., Xu, H., & Fu, F. (2024) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2024.111290 · Cited by 24

Association between per- and polyfluoroalkyl substances and semen quality

Wang, H., Wei, K., Wu, Z., Liu, F., Wang, D., Peng, X., Liu, Y., Xu, J., Jiang, A., & Zhang, Y. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-24182-3 · Cited by 23

PFOA and PFOS breakdown in experimental sand, laboratory-grade water, investigation-derived groundwater and wastewater effluent samples at 50 kGy electron beam dose

Kowald, C., Brorman, E., Shankar, S., Klemashevich, C. L., Staack, D., & Pillai, S. D. (2020) · Radiation Physics and Chemistry · doi:10.1016/j.radphyschem.2020.109323 · Cited by 22

Carry-over rate of per- and polyfluoroalkyl substances to raw milk and human exposure risks in different regions of China

Xiao, K., Li, X., Xu, N., Wang, X., Hao, L., Bao, H., Zhang, L., Shi, Y., & Cai, Y. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.173902 · Cited by 22

Transcriptomic response of Gordonia sp. strain NB4-1Y when provided with 6: 2 fluorotelomer sulfonamidoalkyl betaine or 6: 2 fluorotelomer sulfonate as sole sulfur source

Bottos, E. M., AL-shabib, E. Y., Shaw, D. M. J., McAmmond, B. M., Sharma, A., Suchan, D. M., Cameron, A. D. S., & Van Hamme, J. D. (2020) · Biodegradation · doi:10.1007/s10532-020-09917-8 · Cited by 23

Hunting Metabolic Biomarkers for Exposure to Per- and Polyfluoroalkyl Substances: A Review

Ma, X., Cai, D., Chen, Q., Zhu, Z., Zhang, S., Wang, Z., Hu, Z., Shen, H., & Meng, Z. (2024) · Metabolites · doi:10.3390/metabo14070392 · Cited by 24

Clinical, histological, molecular, and toxicokinetic renal outcomes of per-/polyfluoroalkyl substances (PFAS) exposure: Systematic review and meta-analysis

Hanvoravongchai, J., Laochindawat, M., Kimura, Y., Mise, N., & Ichihara, S. (2024) · Chemosphere · doi:10.1016/j.chemosphere.2024.143745 · Cited by 23

Isomer-Specific Serum Concentrations of Perfluorooctane Sulfonic Acid among U.S. Adults: Results from the National Health and Nutrition Examination Survey (NHANES) and the Study of Women’s Health Across the Nation Multi-Pollutant Study (SWAN-MPS)

Kang, H., Calafat, A. M., Karvonen-Gutierrez, C. A., & Park, S. K. (2022) · Environmental Science & Technology · doi:10.1021/acs.est.2c04501 · Cited by 21

Validating blood microsampling for per- and polyfluoroalkyl substances quantification in whole blood

Partington, J. M., Marchiandi, J., Szabo, D., Gooley, A. A., Kouremenos, K. A., Smith, F., & Clarke, B. O. (2023) · Journal of Chromatography A · doi:10.1016/j.chroma.2023.464522 · Cited by 23

Investigation of the Interaction Mechanism of Perfluoroalkyl Carboxylic Acids with Human Serum Albumin by Spectroscopic Methods

Chen, H., Wang, Q., Cai, Y., Yuan, R., Wang, F., & Zhou, B. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17041319 · Cited by 23

Studying mixture effects on uptake and tissue distribution of PFAS in zebrafish (Danio rerio) using physiologically based kinetic (PBK) modelling

Golosovskaia, E., Örn, S., Ahrens, L., Chelcea, I., & Andersson, P. L. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.168738 · Cited by 21

Relationship of single and co-exposure of per-and polyfluoroalkyl substances and their alternatives with uric acid: A community-based study in China

Liang, L.-X., Lin, L., Zeeshan, M., Zhou, Y., Tang, Y., Chu, C., Zhang, Y., Liu, R.-Q., Feng, W., & Dong, G. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.133500 · Cited by 19

Temporal Trend of Serum Perfluorooctanoic Acid and Perfluorooctane Sulfonic Acid among U.S. Adults with or without Comorbidities in NHANES 1999–2018

Pan, J., Ouyang, C., Zhou, S., Wang, X., Liu, H., Zhang, J., Wang, X., Shi, X., Yang, A., & Hu, X. (2024) · Toxics · doi:10.3390/toxics12050314 · Cited by 20

Associations of exposure to perfluoroalkyl substances with serum uric acid change and hyperuricemia among Chinese women: Results from a longitudinal study

Feng, Y., Fu, M., Guan, X., Wang, C., Meng, H., Zhou, Y., He, M., & Guo, H. (2022) · Chemosphere · doi:10.1016/j.chemosphere.2022.136438 · Cited by 19

The Psychological Impact of Per- and Poly-Fluoroalkyl Substances (PFAS) Pollution in the Veneto Region, Italy: A Qualitative Study with Parents

Menegatto, M., Lezzi, S., Musolino, M., & Zamperini, A. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192214761 · Cited by 21

Interactions of per- and polyfluoroalkyl substances with polypropylene plastic and borosilicate glass: Resolving key uncertainties for accurate analysis

Cao, J., & Xiao, F. (2024) · Journal of Hazardous Materials Advances · doi:10.1016/j.hazadv.2024.100463 · Cited by 19

Exposure to perfluoroalkyl and polyfluoroalkyl substances and estimated glomerular filtration rate in adults: a cross-sectional study based on NHANES (2017–2018)

Liang, Y., Zhou, H. P., Zhang, J., Li, S., Shen, W., & Lei, L. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-26384-9 · Cited by 21

The stage-specific toxicity of per- and polyfluoroalkyl substances (PFAS) in nematode Caenorhabditis elegans

Currie, S. D., Doherty, J. P., Xue, K. S., Wang, J.-S., & Tang, L. (2023) · Environmental Pollution · doi:10.1016/j.envpol.2023.122429 · Cited by 18

A review of current and prospective catalytic routes for the management of PFAs contamination in water

Restivo, J., Orge, C. A., Soares, O. S. G. P., & Pereira, M. F. R. (2024) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2024.112859 · Cited by 18

Multicomponent and Surface Charge Effects on PFOS Sorption and Transport in Goethite-Coated Porous Media under Variable Hydrochemical Conditions

Cogorno, J., & Rolle, M. (2024) · Environmental Science & Technology · doi:10.1021/acs.est.4c02164 · Cited by 19

Environmental Nephrotoxicity Across the Life Course: Oxidative Stress Mechanisms and Opportunities for Early Intervention

Hsu, C., Hou, C., Chen, Y., Chang‐Chien, G., Lin, S.-F., & Tain, Y. (2025) · Antioxidants · doi:10.3390/antiox14101205 · Cited by 22

Associations between the concentrations of α-klotho and selected perfluoroalkyl substances in the presence of eGFR based kidney function and albuminuria: Data for US adults aged 40–79 years

Jain, R. B., & DUCATMAN, A. M. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.155994 · Cited by 15

An automated and high-throughput data processing workflow for PFAS identification in biota by direct infusion ultra-high resolution mass spectrometry

Dudášová, S., Wurz, J., Berger, U., Reemtsma, T., Fu, Q., & Lechtenfeld, O. J. (2024) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-024-05426-2 · Cited by 19

Per- and polyfluoroalkyl substances in environment and potential health impacts: Sources, remediation treatment and management, policy guidelines, destructive technologies, and techno-economic analysis

Chambial, P., Thakur, N., Kushawaha, J., & Kumar, R. (2025) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2025.178803 · Cited by 20

Association between perfluoroalkyl and polyfluoroalkyl internal exposure and serum α-Klotho levels in middle-old aged participants

Li, M., Ma, Y., Cheng, W., Zhang, L., Zhou, C., Zhang, W., & Zhang, W. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1136454 · Cited by 16

Current trends and patterns of PFAS in agroecosystems and environment: A review

Verley, J. C., Mclennon, E., Rein, K. S., Dikgang, J., & Kankarla, V. (2024) · Journal of Environmental Quality · doi:10.1002/jeq2.20607 · Cited by 17

Adsorptive removal of per- and polyfluoroalkyl substances: From conventional porous materials to metal-organic frameworks and covalent organic frameworks

Zhao, G., Zhou, S., Li, J., & Yang⧫, S. (2026) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2026.217673 · Cited by 17

Fluorescence Turn-On/Off Responses of In (III)-MOF to Short-Chain Perfluorocarboxylic Acids

Lv, J., Xie, Y.-B., Xie, L., & Li, J. (2023) · Transactions of Tianjin University · doi:10.1007/s12209-023-00356-z · Cited by 15

H 2 O 2 -catalyzed defluorination of perfluorooctanesulfonate (PFOS) by oxidized vanadium carbide MXene nanosheets

Ye, Y., Steigerwald, J. M., Bang, H., Jones, V., Dennehy, K., & Ray, J. R. (2023) · Journal of Materials Chemistry A · doi:10.1039/d3ta02073h · Cited by 15

Kidney function mediates the effects of four per-and polyfluoroalkyl substances (PFAS) on atherosclerotic cardiovascular disease

Wei, Z., Wei, K., Yang, M., Ying, M., Yin, Z., Wang, N., & Zhang, L. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.117395 · Cited by 16

Persistent organic pollutant perfluorooctanoic acid induces alterations in epigenetic modifications of DNA and RNA

Gu, S.-Y., Feng, T., Gang, F.-Y., Yu, S.-Y., Chan, W., Ma, Z.-C., Gu, Y.-H., & Yuan, B. (2025) · Chinese Chemical Letters · doi:10.1016/j.cclet.2025.110957 · Cited by 15

Concentration of selected liver enzymes across the stages of glomerular function: the associations with PFOA and PFOS

Jain, R. B. (2019) · Heliyon · doi:10.1016/j.heliyon.2019.e02168 · Cited by 14

Ferroptosis in Toxicology: Present and Future

Sinha, B. K. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26146658 · Cited by 15

Decreased levels of perfluoroalkyl substances in patients receiving hemodialysis treatment

Huang, J.-K., Chuang, Y., Wu, P., Tai, C.-J., Lin, J.-R., Kuo, M., Chiu, Y., Hsu, P., Wu, M., Salihović, S., et al. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.165184 · Cited by 12

Silylboronate-Mediated Defluorosilylation of Aryl Fluorides with or without Ni-Catalyst

Zhou, J., Zhao, Z., & Shibata, N. (2021) · Frontiers in Chemistry · doi:10.3389/fchem.2021.771473 · Cited by 13

Neurotoxicity and Potential Mechanisms of Exposure to Per- and Polyfluoroalkyl Substances (PFASs)

Song, Y., Ma, Y., Huang, Y., Song, D., Hu, C., Zhang, X., Chen, Y., Zhang, L., & Lu, L. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05573-2 · Cited by 12

Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) from contaminated water and risk of childhood cancer in California, 2000–2015

Binczewski, N. R., Morimoto, L. M., Wiemels, J. L., Ma, X., Metayer, C., & Vieira, V. M. (2025) · Environmental Epidemiology · doi:10.1097/ee9.0000000000000365 · Cited by 13

The Alarming Effects of Per- and Polyfluoroalkyl Substances (PFAS) on One Health and Interconnections with Food-Producing Animals in Circular and Sustainable Agri-Food Systems

Shurson, G. C. (2025) · Sustainability · doi:10.3390/su17156957 · Cited by 12

Approach based on multiple monolithic fiber solid-phase microextraction coupled to liquid chromatography-tandem mass spectrometry for sensitive determination of perfluoroalkyl acids in fish and seafood

Liao, Y., Ouyang, X., Lü, M., Peng, J., & Huang, X. (2020) · Microchemical Journal · doi:10.1016/j.microc.2020.105189 · Cited by 11

Dietary Exposure of Japanese Quail (Coturnix japonica) to Perfluorooctane Sulfonate (PFOS) and a Legacy Aqueous Film-Forming Foam (AFFF) Containing PFOS: Effects on Reproduction and Chick Survivability and Growth

Bursian, S. J., Link, J. E., McCarty, M., Harr, K. E., Roberts, J., & Simcik, M. F. (2021) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5138 · Cited by 13

Deciphering the Mechanistic Basis for Perfluoroalkyl‐Protein Interactions

Lawanprasert, A., Sloand, J. N., Vargas, M. G., Singh, H., Eldor, T., Miller, M. A., Pimcharoen, S., Wang, J., Leighow, S. M., Pritchard, J. R., et al. (2023) · ChemBioChem · doi:10.1002/cbic.202300159 · Cited by 11

Long-chain perfluoroalkyl carboxylates induce cytoskeletal abnormalities and activate epithelial–mesenchymal transition in both renal cell carcinoma 3D cultures and Caki-1 xenografted mouse model

Lee, B., Kim, Y., Park, H.-J., Im, W., Han, H., Kim, Y., Lim, S., & Yoo, M. H. (2023) · Environment International · doi:10.1016/j.envint.2023.108093 · Cited by 11

Associations between selected perfluoroalkyl acids in serum and hemoglobin in whole blood, a biomarker of anemia: Impact of deteriorating kidney function

Jain, R. B. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.114458 · Cited by 11

Comparative analysis of PFASs concentrations in fur, muscle, and liver of wild roe deer as biomonitoring matrices

Draghi, S., Curone, G., Risoluti, R., Materazzi, S., Gullifa, G., Amoresano, A., Spinelli, M., Fontanarosa, C., Pavlović, R., Pellegrini, A., et al. (2024) · Frontiers in Veterinary Science · doi:10.3389/fvets.2024.1500651 · Cited by 10

Distribution and Ecological Risk Assessment of Perfluoroalkyl and Polyfluoroalkyl Substances in Chinese Soils: A Review

Wang, J., Tsogbadrakh, O., Tian, J., Hai, F. I., Lyu, C., Jiang, G., & Zhu, G. (2025) · Water · doi:10.3390/w17152246 · Cited by 10

Perfluorooctane sulfonate (PFOS) disturbs fatty acid metabolism in Caenorhabditis elegans: Evidence from chemical analysis and molecular mechanism exploration

Wei, C., Zhou, Z., Wang, L., Huang, Z., Liang, Y., & Zhang, J. (2021) · Chemosphere · doi:10.1016/j.chemosphere.2021.130359 · Cited by 10

Exposure to per- and polyfluoroalkyl substances and bone health: a systematic review and meta-analysis

Khosrojerdi, M. A., Lotfi, H., Babaei, Z., mirhamidi, M., & Shahrestanaki, M. K. (2024) · International Journal of Environmental Health Research · doi:10.1080/09603123.2024.2338269 · Cited by 11

Kidney toxicology of a novel compound Lithium Bis(trifluoromethanesulfonyl)imide (LiTFSI, ie. HQ-115) used in energy applications: An epigenetic perspective

Sands, M., Zhang, X., & Irudayaraj, J. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.177019 · Cited by 11

Longitudinal and cross-sectional analysis of perfluoroalkyl substances and kidney function

Eklúnd, A., Taj, T., Dunder, L., Lind, P., Lind, L., & Salihović, S. (2025) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/s41370-025-00785-z · Cited by 10

Nickel‐Catalyzed Carboxylation of Aryl C−F Bonds with CO2

Pei, C., & Wang, B. (2022) · Advanced Synthesis & Catalysis · doi:10.1002/adsc.202101499 · Cited by 9

Exogenous factors associated with legacy PFAS concentrations in the general U.S. population: NHANES 1999-2018

McAdam, J., Jones, L., Romeiko, X. X., & Bell, E. (2024) · Water Emerging Contaminants & Nanoplastics · doi:10.20517/wecn.2024.05 · Cited by 11

Impact of the increasing concentrations of selected perfluoroalkyl acids on the observed concentrations of red blood cell folate among US adults aged ≥20 years

Jain, R. B. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-14454-9 · Cited by 9

Role of per- and polyfluoroalkyl substances in the cardiorenal system: Unraveling crosstalk from the network of pollutants and phenotypes

Yang, M., Zhao, J., An, Z., Li, H., Ma, C., Lv, J., Xiao, F., Tan, Z., Li, L., Zhang, X., et al. (2024) · Journal of Environmental Sciences · doi:10.1016/j.jes.2024.03.022 · Cited by 8

Legacy and emerging per- and polyfluoroalkyl substances (PFAS) in marine food webs from Liaodong Bay: Levels, bioaccumulation, biomagnification and source apportionment

Zhu, H., Wu, G., Zhao, C., Yang, L., Yang, X. H., Zhao, X., Yin, Q., Li, Z., Jin, H., Zhao, S., et al. (2026) · Water Research · doi:10.1016/j.watres.2025.125315 · Cited by 8

Suitability of Remediated Heat-Treated Soil in Concrete Applications

Fehérvári, A., MacLeod, A. J. N., Gallage, C., Collins, F., Callahan, D. L., & Gates, W. P. (2022) · Journal of Environmental Management · doi:10.1016/j.jenvman.2022.117076 · Cited by 8

Perfluorooctane sulfonate causes HK-2 cell injury through ferroptosis and endoplasmic reticulum stress pathways

Yan, S., Ma, H., Ren, Y., Wang, P., Liu, D., Ding, N., Liu, Y., Chen, Q., Ren, S., & Mou, Y. (2024) · Toxicology and Industrial Health · doi:10.1177/07482337241300722 · Cited by 8

Association between exposure to per- and polyfluoroalkyl substances and kidney function: a population study

Zhang, X., Cao, Y., Yang, X., Ma, F., Zhang, H., & Xiao, W. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1569031 · Cited by 8

Individual and joint associations of exposure to per- and polyfluoroalkyl substances with children's mitochondrial DNA copy number, and modified by estimated glomerular filtration rate

Zhang, B., Wang, J., Zhang, Y., Liu, M., & Zhang, X. (2024) · Environmental Research · doi:10.1016/j.envres.2024.120598 · Cited by 7

Perfluoroalkyl acids interact with major human blood protein fibrinogen: Experimental and computation study

Đelmaš, A. Đ., Šeba, T., Gligorijević, N., Pavlović, M., Gruden, M., Nikolic, M. R., Milčić, K., & Milčić, M. K. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.141425 · Cited by 8

Influence of Area, Age and Sex on Per- and Polyfluorinated Alkyl Substances Detected in Roe Deer Muscle and Liver from Selected Areas of Northern Italy

Draghi, S., Curone, G., Pavlović, R., Cesare, F. D., Cagnardi, P., Silva, C. F., Pellegrini, A., Riva, F., Arioli, F., & Fidani, M. (2024) · Animals · doi:10.3390/ani14040529 · Cited by 8

Long-term impact of per- and polyfluoroalkyl substances on kidney health: a large-scale genetic study

Zeng, D., Liu, J., Wang, Y., & Huang, Z. (2025) · Environmental Sciences Europe · doi:10.1186/s12302-025-01189-4 · Cited by 6

Finding a way out? Comprehensive biotransformation study of novel fluorinated surfactants

Licul-Kucera, V., Frömel, T., Kruså, M., van Wezel, A. P., & Knepper, T. P. (2023) · Chemosphere · doi:10.1016/j.chemosphere.2023.139563 · Cited by 7

Lipid responses to perfluorooctane sulfonate exposure for multiple rat organs

Yen, T.-H., Lee, S.-H., Tang, C., Liang, H., & Lin, C. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116368 · Cited by 6

Changes in Plasma Concentrations of Per- and Polyfluoroalkyl Substances after Bariatric Surgery in Adolescents from the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-Labs) Study

Baumert, B. O., Eckel, S. P., Goodrich, J. A., Li, Z., Stratakis, N., Walker, D. I., Zhao, Y., Fischer, F. C., Bartell, S. M., Valvi, D., et al. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.172840 · Cited by 7

Towards a Better Understanding of the Human Health Risk of Per- and Polyfluoroalkyl Substances Using Organoid Models

Xu, H., Kang, J., Gao, X., Lan, Y., & Li, M. (2025) · Bioengineering · doi:10.3390/bioengineering12040393 · Cited by 6

Per- and Polyfluoroalkyl Substances: An Emerging Contaminant of Concern

Anderko, L., Pennea, E., & Chalupka, S. M. (2019) · Annual Review of Nursing Research · doi:10.1891/0739-6686.38.159 · Cited by 6

Impact of Firefighting Aqueous Film-Forming Foams on Human Cell Proliferation and Cellular Mortality

Kafkoutsou, A. L., Yang, Y.-P., Zeynaloo, E., Deo, S. K., Solle, N. S., Kobetz, E. N., Daunert, S., & Caban-Martinez, A. J. (2022) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0000000000002527 · Cited by 6

Factors affecting serum PFAS concentrations among US females with surgically and naturally induced menopause: data from NHANES 2003–2018

Jain, R. B., & DUCATMAN, A. M. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-28395-y · Cited by 6

Inflammation mediates the association between per- and polyfluoroalkyl substance exposure and kidney function: Integrating epidemiological and animal evidence

Liang, L.-X., Bao, W.-W., Chu, C., Wu, L.-Y., Amjad, M., Zhang, Y.-T., He, W.-T., Huang, J.-W., Lin, L.-Z., Zhou, Y., et al. (2026) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2026.141320 · Cited by 5

Association Between Serum Levels of Perfluoroalkyl and Polyfluoroalkyl Substances and Dental Floss Use: The Double‐Edged Sword of Dental Floss Use—A Cross‐Sectional Study

Jiao, Y., Zhuo, F., & Ni, X. (2025) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.14126 · Cited by 5

Esterification of perfluorinated carboxylic acids with bromomethyl aromatic compounds for gas chromatography combined with laser ionization mass spectrometry

Wen, L., Jin, F., Imasaka, T., & Imasaka, T. (2021) · Journal of Chromatography A · doi:10.1016/j.chroma.2021.462546 · Cited by 5

Proteomic insights from extracellular vesicles into the molecular mechanisms of health effects induced by Per- and polyfluoroalkyl substances

Li, Y., Luo, Y., Liu, Y., Li, N., Huang, K., Li, L., Li, Z., Han, C. Q., Zhu, N., Wang, Y., et al. (2024) · Journal of Environmental Sciences · doi:10.1016/j.jes.2024.03.034 · Cited by 4

Advanced Photothermal Spectroscopy for Trace PFAS Detection

Zhao, Y., Jannabhatla, N. K., & Thundat, T. G. (2025) · ECS Sensors Plus · doi:10.1149/2754-2726/ada4bc · Cited by 4

Perfluorooctane Sulfonate (PFOS) and Related Compounds Induce Nuclear Receptor 4A1 (NR4A1)-Dependent Carcinogenesis

Hailemariam, A., Upadhyay, S., Srivastava, V. K., Hafiz, Z., Zhang, L., Tsui, W. N. T., Oany, A. R., Rivera-Rodriguez, J., Chapkin, R. S., Riddell, N., et al. (2025) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.4c00528 · Cited by 4

Differential impact of per- and polyfluoroalkyl substances exposure on hypertension risk by kidney function and metabolic status

Kim, Y., Lee, I., Lee, J., Lee, G., Paek, J. H., Han, S., Kho, Y., Lim, C. S., Choi, K., & Lee, J. P. (2025) · Environment International · doi:10.1016/j.envint.2025.109930 · Cited by 4

Per- And Poly-Fluoroalkyl Substances (PFAS) Exposure and Risk of Breast, and Female Genital Cancers: A Systematic Review and Meta-Analysis

Seyyedsalehi, M. S., Kappil, E. M., Zhang, S., Zheng, T., & Boffetta, P. (2024) · La Medicina del Lavoro · doi:10.23749/mdl.v115i6.16330 · Cited by 4

Associations Between Perfluoroalkyl Substances Mixed Exposure and Uric Acid and Glomerular Filtration Rate Among Adolescents and Adults

Wang, X., Yan, W. S., Xie, H., & Huang, S. (2023) · Exposure and Health · doi:10.1007/s12403-023-00551-2 · Cited by 4

Stress granule reporter system to assess perfluorooctanoic acid gastric toxicity in vitro

Lee, J.-M., Kim, K. K., & Kim, E.-M. (2024) · Molecular & Cellular Toxicology · doi:10.1007/s13273-024-00474-2 · Cited by 3

Temperature–Electrokinetic Co-Driven Perfluorooctane Sulfonic Acid (PFOS) Adsorption on Geo-Adsorbents

Yin, Y., Shan, Y., Wei, J., Ma, D., Zhan, M., Yang, L., Lou, B., Lou, B., Zhang, B., & Jiao, W. (2023) · Processes · doi:10.3390/pr11061856 · Cited by 3

Interspecies comparison of metabolism of two novel prototype PFAS

Licul-Kucera, V., Ragnarsdóttir, O., Frömel, T., van Wezel, A. P., Knepper, T. P., Harrad, S., & Abdallah, M. A. (2024) · Chemosphere · doi:10.1016/j.chemosphere.2024.141237 · Cited by 5

Observational suspected adverse drug reaction profiles of fluoro-pharmaceuticals and potential mimicry of per- and polyfluoroalkyl substances (PFAS) in the United Kingdom

Balasubramaniam, B., & Jones, A. M. (2025) · PLoS ONE · doi:10.1371/journal.pone.0331286 · Cited by 2

Investigation of Combined Toxic Metals, PFAS, Volatile Organic Compounds, and Essential Elements in Chronic Kidney Disease

Adetunji, A. G., & Obeng-Gyasi, E. (2025) · Journal of Xenobiotics · doi:10.3390/jox15060202 · Cited by 2

Urine-to-Blood Partitioning of Per- and Polyfluoroalkyl Substances in Human Biomonitoring: Implications for Environmental Exposure Analysis and Bioaccumulation Assessment

Ye, P., Bai, H., Shi, J., Dong, Z., & Luo, K. (2026) · Molecules · doi:10.3390/molecules31111880 · Cited by 2

Perfluorononanoic acid as a risk factor for metabolic syndrome: A case-control study

Zhang, L., Du, J. K., Sang, C., Liu, L., & Shao, B. (2024) · Emerging contaminants · doi:10.1016/j.emcon.2024.100396 · Cited by 2

Effect of polyfluoroalkyl chemicals on the occurrence of urge urinary incontinence: a population-based study

Cui, S., Zhao, X., Chu, X., Zhang, S., Gu, Q., & Xu, C. (2021) · Therapeutic Advances in Urology · doi:10.1177/17562872211029799 · Cited by 2

Serum concentrations of perfluoro-1-heptane sulfonate (PFHpS) among US adults: variabilities across different stages of kidney function

Jain, R. B. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-23881-1 · Cited by 2

Toxicity and Health Risks of PFAS

Dhanasinghe, C., Lin, W., Kao, C., Surampalli, R. Y., & Zhang, T. C. (2025) · Wiley eBooks · doi:10.1002/9781394343935.ch9 · Cited by 2

Renal Disease in the Tropics

Alexander, S., & John, G. T. (2023) · Elsevier eBooks · doi:10.1016/b978-0-7020-7959-7.00070-1 · Cited by 1

Confronting Novel Alternatives of Per- and Polyfluoroalkyl Substances: From the Exposure Pathway to the Health Risk Estimation

Gao, Y., Zhang, Z., Luo, H., Yan, X., Liu, Y., Zhang, K., Wei, Y., & Liu, Y. (2025) · Processes · doi:10.3390/pr13124032 · Cited by 1

An Overview of Emerging Per and Polyfluoroalkyl Substances; Environmental Occurrence, Health Effects, Treatment Approaches and Sustainable Alternatives

Monisha, M., Gopalakrishnan, M., Kulandaivel, T., Janjaroen, D., & Ganesan, S. (2025) · Journal of Vinyl and Additive Technology · doi:10.1002/vnl.70054 · Cited by 1

A coordination polymer based on tetranuclear Tb 3+ clusters exhibiting dual turn-on/off fluorescence sensing of long- and short-chain polyfluoroalkyl substances

Long, C., Chen, Z., Ye, J., Ma, S., Xu, E., Qiao, Y., Gao, M., Zhou, X., Zheng, F., Yang, X., et al. (2026) · Inorganic Chemistry Frontiers · doi:10.1039/d5qi02550h · Cited by 1

From environment to organs: individual and combined effects of MPs and PFAS on urinary system health

Li, D., Wang, T., Zhang, W., Li, M., Du, W., & Wang, J. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1782952 · Cited by 2

Non-Negligible Source of PFOS: Biochemical Fate and Metabolic Activation of Precursors

Tang, W., Wang, X., Lv, J., Hu, J., Chen, Y., Xu, D., Tao, L., Covaci, A., & Huang, Y. (2026) · Environmental Science & Technology · doi:10.1021/acs.est.6c04547 · Cited by 1

Per- and poly-fluoroalkyl substances (PFASs) in drinking water and related health effects

Kumara, M. K., & Bhattacharyya, D. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-99906-9.00016-4 · Cited by 1

Environmental Nephrotoxins

Ding, J., & Etzel, R. A. (2023) · Springer eBooks · doi:10.1007/978-3-031-11665-0_73 · Cited by 1

Differential associations between synthetic endocrine disruptors and renal function impairment across varying degrees in middle-aged and older adult populations

Mu, J., Li, Y., He, L., Ma, M., Zhang, M., Wang, X., & Mao, D. (2025) · Frontiers in Public Health · doi:10.3389/fpubh.2025.1526070 · Cited by 1

Perfluorinated Compound Exposure and Health Effects in Humans

Li, J., & Ge, R. (2019) · Springer eBooks · doi:10.1007/978-981-32-9535-3_9 · Cited by 1

Statewide sampling to determine spatial distribution, prevalence, and occurrence of per- and polyfluoroalkyl substances (PFAS) in Illinois community water supplies, 2020–21

Gahala, A. M., Sharpe, J. B., & Williams, A. M. (2023) · Scientific investigations report · doi:10.3133/sir20235078 · Cited by 1

A Review of the Current Cervical Cancer Screening Guidelines

Perkins, A. C., & Skinner, E. N. (2016) · North Carolina Medical Journal · doi:10.18043/ncm.77.6.420 · Cited by 7

Clinical, histological, molecular, and toxicokinetic renal outcomes of per-/polyfluoroalkyl substances (PFAS) exposure: Systematic review and meta-analysis

Hanvoravongchai, J., Laochindawat, M., Kimura, Y., Mise, N., & Ichihara, S. (2024) · Chemosphere · doi:10.1016/j.chemosphere.2024.143745 · Cited by 23

Kidney Risks Linked to Per‐ and Polyfluoroalkyl Substance Exposure

Chávez‐Valencia, V., & Lagunas‐Rangel, F. A. (2026) · Environmental Toxicology · doi:10.1002/tox.70197

Perfluoroalkyl substances exposure and kidney function decline in a community-based prospective cohort

Chen, C., Lee, C., Sun, C., Chen, Y.-T., Pan, H., Liu, Y.-A., Hsu, C.-K., & Hsu, H.-J. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.119015 · Cited by 10

Associations of per- and polyfluoroalkyl substances exposure with kidney function in the Korean general population

Choi, H. J., Lim, W., Huh, D., Kim, L., Park, K., Lee, J., Hwang, S., & Moon, K. W. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.119462 · Cited by 4