Recent Evidence on Alcohol and Cancer Epidemiology
Abstract
This review presents an overview of the impact of alcohol consumption on cancer risk. Results from the 2009 International Agency for Research on Cancer monograph as well as the most recent meta-analyses and epidemiological studies are considered. Alcohol consumption is one of the most important known risk factors for human cancer and potentially one of the most avoidable factors, but it is increasing worldwide. Ethanol in alcoholic beverages is carcinogenic to humans and causes several cancers (oral cavity, pharynx, larynx, esophagus, colorectum, liver and female breast). Cumulative lifetime consumption, frequency and drinking pattern appear to play a role in risk characterization. While the role of heavy drinking has been long recognized, new evidence suggests that light consumption (up to one drink/day) is also associated with adverse effects. In addition, some genetic polymorphisms interact with alcohol metabolism and may modify its impact.
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The increase in risk of developing cancer for increasing average daily alcohol consumed is linear on an exponentiated scale, but the magnitude varies by cancer site.
“The increase in the risk of developing cancer (stratified by cancer site) for increasing average daily amounts of alcohol consumed (measured in grams of pure alcohol consumed per day) has been observed to be linear on an exponentiated scale; however, the magnitude of these risk increases varies by cancer site 169, 170, 171.”
From The relationship between different dimensions of alcohol use and the burden of disease—an update (2017) · cites this paper as [171]
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- Authors
- Scoccianti, C., Straif, K., & Romieu, I.
- Affiliations
- Centre international de recherche sur le cancer (FR)
- International Agency for Research on Cancer, Monographs Section, 150 Cours Albert Thomas, 69372Lyon Cedex 08, France
- Venue
- Future Oncology
- Publisher
- Informa UK Limited
- Published
- 2013-08-28
- Volume
- 9
- Issue
- 9
- Pages
- 1315-1322
- ISSN
- 1479-6694 (ISSN-L)
- 1744-8301
- OpenAlex
- W2129830955
- Cited by
- 52
- References
- 84
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 5 · 2020: 7 · 2019: 3 · 2018: 5 · 2017: 5 · 2016: 4 · 2015: 9 · 2014: 6 · 2013: 1
- FWCI
- 0.98
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Future Oncology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Surgery › Esophageal Cancer Research and Treatment
- Health Sciences › Medicine › Otorhinolaryngology › Head and Neck Cancer Studies
- Keywords
- alcohol consumption, cancer risk, oral cancer, pharyngeal cancer, laryngeal cancer, esophageal cancer, colorectal cancer, liver cancer, breast cancer, drinking patterns, light drinking, genetic polymorphism, alcohol metabolism, IARC Monographs
- MeSH terms
- Alcohol Drinking, Humans, Neoplasms
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