The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Ph-Sensitive Polymeric Nanoparticles for Tumor-Targeting Doxorubicin Delivery: Concept and Recent Advances
Abstract
Doxorubicin is a potent chemotherapeutic drug applied in the clinics for the treatment of various human cancers. It is typically administered as the hydrochloride salt or in liposomal forms, which are plagued with severe side effects. In recent years, pH-sensitive polymeric nanoparticles that are capable of retaining drug during circulation while actively releasing it at the tumor site and/or inside the target tumor cells have received an overwhelming interest for tumor-targeting cancer chemotherapy. This smart delivery approach has shown to elegantly resolve the in vivo stability versus intracellular drug release dilemma, as well as stealth versus tumor cell uptake dilemma. In this review, the concept and exciting new advances in pH-sensitive polymeric nanoparticles for doxorubicin delivery are presented and discussed.
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Cites
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Oxime Linkage: A Robust Tool for the Design of pH-Sensitive Polymeric Drug Carriers
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The Smart Drug Delivery System and Its Clinical Potential
Liu, D., Yang, F., Xiong, F., & Gu, N. (2016) · Theranostics · doi:10.7150/thno.14858 · Cited by 1,066
Nanoparticle-Based Immunotherapy for Cancer
Shao, K., Singha, S., Clemente-Casares, X., Tsai, S., Yang, Y., & Santamaria, P. (2015) · ACS Nano · doi:10.1021/nn5062029 · Cited by 470
Extracellular vesicle-based drug delivery systems for cancer treatment
Walker, S., Busatto, S., Pham, A., Tian, M., Suh, A., Carson, K., Quintero, A., Lafrence, M., Malik, H., Santana, M. X., et al. (2019) · Theranostics · doi:10.7150/thno.37097 · Cited by 429
The potential of protein–nanomaterial interaction for advanced drug delivery
Peng, Q., & Mu, H. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.01.041 · Cited by 134
Drug delivery based on stimuli-responsive injectable hydrogels for breast cancer therapy: A review
Xin, H., & Naficy, S. (2022) · Gels · doi:10.3390/gels8010045 · Cited by 83
Metadata
- Authors
- Meng, F., Zhong, Y., Cheng, R., Deng, C., & Zhong, Z.
- Venue
- Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2014-03
- Volume
- 9
- Issue
- 3
- Pages
- 487-499
- ISSN
- 1743-5889 (ISSN-L)
- 1748-6963
- OpenAlex
- W2140486739
- Cited by
- 188
- References
- 6
- FWCI
- 9.56
- Type
- journal article
- Language
- en
- Open access
- closed
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- Meng, F., Zhong, Y., Cheng, R., Deng, C., & Zhong, Z. (2014). Ph-Sensitive Polymeric Nanoparticles for Tumor-Targeting Doxorubicin Delivery: Concept and Recent Advances. Nanomedicine. https://doi.org/10.2217/nnm.13.212
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
