The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
The Impact of Nanoparticle Protein Corona on Cytotoxicity, Immunotoxicity and Target Drug Delivery
Open accessAbstract
In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream where they circulate until they reach the target tissue. The ligand on the NP surface recognizes its specific receptor expressed on the target tissue and the drug is released in a controlled manner. However, once injected in a physiological environment, NPs interact with biological components and are surrounded by a protein corona (PC). This can trigger an immune response and affect NP toxicity and targeting capabilities. In this review, we provide a survey of recent findings on the NP-PC interactions and discuss how the PC can be used to modulate both cytotoxicity and the immune response as well as to improve the efficacy of targeted delivery of nanocarriers.
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Cites
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Time Evolution of the Nanoparticle Protein Corona
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Surface hydrophobin prevents immune recognition of airborne fungal spores
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Cited by
Protein corona: a new approach for nanomedicine design
Nguyen, V. H., & Lee, B.-J. (2017) · International Journal of Nanomedicine · doi:10.2147/ijn.s129300 · Cited by 638
Carbon Nanotubes: Smart Drug/Gene Delivery Carriers
Zare, H., Ahmadi, S., Ghasemi, A., Ghanbari, M., Rabiee, N., Bagherzadeh, M., Karimi, M., Webster, T. J., Hamblin, M. R., & Mostafavi, E. (2021) · International Journal of Nanomedicine · doi:10.2147/ijn.s299448 · Cited by 452
Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers
Zhao, Z., Ukidve, A., Krishnan, V., & Mitragotri, S. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2019.01.002 · Cited by 444
Biological Identity of Nanoparticles In Vivo : Clinical Implications of the Protein Corona
Caracciolo, G., Farokhzad, O. C., & Mahmoudi, M. (2017) · Trends in Biotechnology · doi:10.1016/j.tibtech.2016.08.011 · Cited by 426
Biocompatibility of nanomaterials and their immunological properties
Kyriakides, T. R., Raj, A., Tseng, T. H., Xiao, H., Nguyen, R., Mohammed, F. S., Halder, S., Xu, M., Wu, M. J., Bao, S., et al. (2021) · Biomedical Materials · doi:10.1088/1748-605x/abe5fa · Cited by 389
Metadata
- Authors
- Corbo, C., Molinaro, R., Parodi, A., Toledano Furman, N. E., Salvatore, F., & Tasciotti, E.
- Venue
- Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2015-12-11
- Volume
- 11
- Issue
- 1
- Pages
- 81-100
- ISSN
- 1743-5889 (ISSN-L)
- 1748-6963
- OpenAlex
- W2194502287
- Cited by
- 692
- References
- 13
- FWCI
- 13.50
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Corbo, C., Molinaro, R., Parodi, A., Toledano Furman, N. E., Salvatore, F., & Tasciotti, E. (2016). The Impact of Nanoparticle Protein Corona on Cytotoxicity, Immunotoxicity and Target Drug Delivery. Nanomedicine. https://doi.org/10.2217/nnm.15.188
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
