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SALIVARY CHROMOGRANIN A AS AN INDEX OF PSYCHOSOMATIC STRESS RESPONSE
Open accessAbstract
Chromogranin A (CgA) is a major protein in adrenal chromaffin cells and adrenargic neurons.CgA and catecholamines are co-released into extra-cellular environment.We measured changes in the concentrations of CgA-like immunoreactivity (CgA-like IR), catecholamines and cortisol in saliva and plasma by exposure to stress in male volunteers.We found a prompt elevation of salivary CgA-like IR level prior to an elevation of salivary cortisol level in psychosomatic stresses (oral presentation and car driving).Salivary CgA-like IR level showed apparently no change during continuous physical exercise, while plasma noradrenaline level increased immediately.These results suggest strongly that salivary CgA-like IR can be a sensitive and substantial index for psychosomatic stress.
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Cited by
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Nakamura, H., Takishima, T., Kometani, T., & Yokogoshi, H. (2009) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637480802558508 · Cited by 116
Staley, M., Conners, M. G., Hall, K., & Miller, L. J. (2018) · Hormones and Behavior · doi:10.1016/j.yhbeh.2018.04.011 · Cited by 100
Kawano, A., & Emori, Y. (2015) · Journal of the American Psychiatric Nurses Association · doi:10.1177/1078390314566882 · Cited by 57
Metadata
- Authors
- NAKANE, H., ASAMI, O., YAMADA, Y., HARADA, T., MATSUI, N., KANNO, T., & YANAIHARA, N.
- Venue
- Biomedical Research
- Publisher
- Biomedical Research Press
- Published
- 1998
- Volume
- 19
- Issue
- 6
- Pages
- 401-406
- ISSN
- 0388-6107 (ISSN-L)
- 1880-313X
- OpenAlex
- W1985839526
- Cited by
- 184
- References
- 0
- FWCI
- 1.04
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: SALIVARY CHROMOGRANIN A AS AN INDEX OF PSYCHOSOMATIC STRESS RESPONSE. https://app.cochat.ai/papers/10.2220/biomedres.19.401
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- NAKANE, H., ASAMI, O., YAMADA, Y., HARADA, T., MATSUI, N., KANNO, T., & YANAIHARA, N. (1998). SALIVARY CHROMOGRANIN A AS AN INDEX OF PSYCHOSOMATIC STRESS RESPONSE. Biomedical Research. https://doi.org/10.2220/biomedres.19.401
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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