Pre-administration of vitamin C reduces exercise-induced oxidative stress in untrained subjects
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We investigated the effects of a 40 min bout of bicycle exercise, and the effects of vitamin C administration 12 h before exercise, on the serum markers of oxidative stress in young untrained subjects. Increased levels of malondialdehyde, the marker of the lipid peroxidation, and a decrease in specific activity of the antioxidant enzyme glutathione peroxidase that were observed as a result of exercise, pointed to the presence of exercise-induced oxidative stress. These markers were reduced by pre-administration of vitamin C. The results suggest that physically active subjects could increase their daily dietary vitamin C intake in order to reinforce their antioxidant defenses prior to exercise training.
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Our group previously showed that preadministration of vitamin C could prevent some oxidative stress manifestations, generated as a result of 40-minute bout of bicycle exercise in young untrained subjects.
“Also, our group previously showed that preadministration of vitamin C, for example, could prevent some oxidative stress manifestations, generated as a result of 40-minute bout of bicycle exercise in young untrained subjects [316].”
From Oxidative Stress Implications in the Affective Disorders: Main Biomarkers, Animal Models Relevance, Genetic Perspectives, and Antioxidant Approaches (2016) · cites this paper as [316]
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Self-citation
- Authors
- Trofin, F.-P., Chirazi, M., Honceriu, C., Drosescu, P., Grădinariu, G., Vorniceanu, A., Anton, E., Cojocaru, D., Ciobica, A., Ciornea, E., & Cojocaru, I.
- Affiliations
- Alexandru Ioan Cuza University (RO)
- Grigore T. Popa University of Medicine and Pharmacy (RO)
- Venue
- Archives of Biological Sciences
- Publisher
- National Library of Serbia
- Published
- 2014
- Volume
- 66
- Issue
- 3
- Pages
- 1179-1185
- ISSN
- 0354-4664 (ISSN-L)
- 1821-4339
- OpenAlex
- W2050090998
- Cited by
- 3
- References
- 28
- Citations by year
- 2026: 1 · 2016: 1 · 2015: 1
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Archives of Biological Sciences (publishedVersion, cc-by-nc-nd)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Health Sciences › Nursing › Nutrition and Dietetics › Vitamin C and Antioxidants Research
- Keywords
- vitamin C, exercise-induced oxidative stress, lipid peroxidation, malondialdehyde, glutathione peroxidase, antioxidant defense, untrained subjects, cycling exercise, pre-workout supplements, dietary vitamin C intake
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