The effects of delta rays on the number of particle-track traversals per cell in laboratory and space exposures
Abstract
It is a common practice to estimate the number of particle-track traversals per cell or cell nucleus as the product of the ion's linear energy transfer (LET) and cell area. This practice ignores the effects of track width due to the lateral extension of delta rays. We make estimates of the number of particle-track traversals per cell, which includes the effects of delta rays using radial cutoffs in the ionization density about an ion's track of 1 mGy and 1 cGy. Calculations for laboratory and space radiation exposures are discussed, and show that the LET approximation provides a large underestimate of the actual number of particle-track traversals per cell from high-charge and energy (HZE) ions. In light of the current interest in the mechanisms of radiation action, including signal transduction and cytoplasmic damage, these results should be of interest for radiobiology studies with HZE ions.
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During transit outside LEO, every cell nucleus within an astronaut would be traversed, on average, by a hydrogen ion every few days and by heavier HZE nuclei every few months.
“During transit outside of LEO, every cell nucleus within an astronaut would be traversed, on average, by a hydrogen ion every few days and by heavier HZE nuclei (e.g., 16O, 28Si, 56Fe) every few months [12].”
From Space Radiation: The number one risk to astronaut health beyond low earth orbit (2014) · cites this paper as [12]
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- Authors
- Cucinotta, F. A., Nikjoo, H., & Goodhead, D. T.
- Affiliations
- Johnson Space Center (US)
- Venue
- Radiation Research
- Publisher
- JSTOR
- Published
- 1998-07
- Volume
- 150
- Issue
- 1
- Pages
- 115
- ISSN
- 0033-7587 (ISSN-L)
- OpenAlex
- W2061995059
- Cited by
- 134
- References
- 19
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 8 · 2022: 2 · 2021: 3 · 2020: 3 · 2019: 2 · 2018: 6 · 2017: 6 · 2016: 9 · 2015: 9 · 2014: 8 · 2013: 10 · 2012: 6
- FWCI
- 3.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Radiation Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Radiation Therapy and Dosimetry
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Effects of Radiation Exposure
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Radiation Effects in Electronics
- Keywords
- delta rays, linear energy transfer, track width, ionization density, space radiation exposure, cytoplasmic damage, signal transduction
- MeSH terms
- Cells, DNA, DNA Damage, Humans, Radiation Protection, Radiobiology, Linear Energy Transfer
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