Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I

Turner, Nigel, Li, Jing-Ya, Gosby, Alison, To, Sabrina W.C., Cheng, Zhe, Miyoshi, Hiroyuki, Taketo, Makoto M., Cooney, Gregory J. +5 more·2008·Diabetes
DOI 10.2337/db07-1552

Cited by (541)

Items 501–541 of 541

  1. Current literature in diabetes
    2008 · Diabetes/Metabolism Research and Reviews
  2. The current state of diabetes treatment
    Michael K. Danquah, Jaison Jeevanandam · 2022 · Elsevier eBooks
  3. Mitohormesis
    Ivo F. Machado, João Soeiro Teodoro, Ana Catarina Castela, Carlos M. Palmeira, Anabela Pinto Rolo · 2021 · Elsevier eBooks
  4. How does berberine regulate metabolism through target cells?
    Aru Sun, Haoyu Yang, Tao Li, Jinli Luo, Ling Zhou, Rui Chen, Yiqun Lin, Lin Han · 2023
  5. Assessment of Two Plant Extracts and Native Lactobacillus Cultures on Performance, Gut Microbiota, and Serum Lipid Parameters in Broiler Chickens
    Amin Dibamehr, Mohsen Daneshyar, Amir Tukmechi, Seyyed Meysam Abtahi Froushani · 2023 · SSRN Electronic Journal
  6. Bioprospecting ethnopharmacological plants for endophytic fungal drug discovery
    Shivam Buddha, Lokesh Gambhir, Yogesh Kumar, Gaurav Sharma, Asha Sharma, Neha Kapoor · 2025 · Elsevier eBooks
  7. Research progress on berberine and its derivatives
    Jina Sun, Jinlin Wang, Xiong Xie, Jiang Wang, Yu Zhou, Hong Liu · 2025 · Scientia Sinica Chimica
  8. Comparative study of efficacy and safety of berberine hydrochloride versus metformin in newly diagnosed prediabetic patients: a randomized clinical trial
    Prashant S. Chaudhary, Shweta V. Deshmukh, Deepali L. Jaybhaye, Sukhmeen Kaur · 2025 · International Journal of Basic & Clinical Pharmacology
  9. Mécanisme d'action d'une nouvelle molécule E008 sur les flux métaboliques hépatiques et l'oxydation phosphorylante mitochondriale
    Anne‐Laure Borel · 2009 · OpenGrey (Institut de l'Information Scientifique et Technique)
  10. Additional file 1 of Berberine increases stromal production of Wnt molecules and activates Lgr5+ stem cells to promote epithelial restitution in experimental colitis
    Zecheng Luo, Li, Zihao, Zheng Liang, Wang, Lin, He, Guanlin, Wang, Dongdi, Lei Shen, Wang, Zhengting, Ma, Xiuying, 耿福能 et al. · 2023 · Figshare
  11. Additional file 2 of Berberine increases stromal production of Wnt molecules and activates Lgr5+ stem cells to promote epithelial restitution in experimental colitis
    Zecheng Luo, Li, Zihao, Zheng Liang, Wang, Lin, He, Guanlin, Dongdi Wang, Lei Shen, Wang, Zhengting, Ma, Xiuying, 耿福能 et al. · 2023 · Figshare
  12. Molecular Mechanisms of Monomer Compounds from Chinese Herbal Medicine in Regulating Oxidative Phosphorylation for Intervention in Diabetic Kidney Disease
    程倩 尹 · 2025 · Traditional Chinese Medicine
  13. Natural products in the management of type 2 diabetes mediated neurological complications
    Rahul Kumar, Ankita Devi, Anamika Sharma, Suman Karadagatla, Shovit Ranjan · 2026 · Elsevier eBooks
  14. The black barberry diet decreases oxidative stress and improves behavioral functions in adult male rats induced tramadol neurodegeneration: behavioral, molecular and histopathological studies
    Azam Sajjadi Nasab, Amir Masoud Dalband, Ibrahim Mohammadzadeh, Zahrasadat Lajevardi, Maral Moafi, Mohammad Javad Ebrahimi, Seyedeh Naghmeh Nourirad, Alireza Asadi, Arsham Efazati, Amirreza Dowlati Beirami et al. · 2026 · 3 Biotech
  15. Bioactive Compounds from Plants for Disease Prevention and Management
    Iriny M. Ayoub, Nehal Ibrahim, Yosra A. El Khodary, Abdel Nasser B. Singab · 2026 · Sustainability Sciences in Asia and Africa
  16. Modulation of NFκB Signaling by Natural Compounds in Sarcoma and Normal Muscle Models
    Justyna Radzka, Agnieszka Gizak, Dagmara Baczyńska, Adam Junka, Bartłomiej Dudek, Malwina Brożyna, Anna Szewczyk, Julita Kulbacka · 2026 · International Journal of Molecular Sciences
  17. Recent advances in integrative medicine: Current challenges and future recommendations
    Ayesha Rao, Javed Iqbal M, Aziz-ur-Rehman, Ibrahim A. Alsarra · 2026 · Elsevier eBooks
  18. Dihydroberberine regulates the ferroptosis-autophagy positive feedback loop in colorectal cancer by targeting PANX2
    Libin Xu, Qingqi Meng, Fang Wang, Yan Mi, Yuzhen Jia, Ning Lei, Dakuo He, Yue Hou · 2026 · Phytomedicine
  19. Supra-additive neuroprotective effects of berberine–metformin combination in diabetic encephalopathy: Chou–Talalay synergy quantification, AMPK–Nrf2 axis modulation, and pharmacokinetic verification
    Wessam Mansour Filfilan, Mohamed E. El‐Beeh · 2026 · Metabolic Brain Disease
  20. Targeting Ferroptosis: Effects and Mechanisms of Action of Berberine
    Ting Yuan David Cheng, Hu Xi, Wenjie Hao, Yi Yang, Naisi Qian, Wenming Yang · 2026 · The American Journal of Chinese Medicine
  21. Decoding the PI3K/Akt/mTOR-AMPK signalling nexus: molecular crosstalk, metabolic reprogramming and therapeutic targeting in human disease
    Josef Yakin, Faruk Alam, Jose Fernando G. Elpa · 2026 · Journal of Immunoassay and Immunochemistry
  22. Metabolic-epigenetic axis in cardiovascular inflammatory injury: regulatory mechanisms and intervention strategies
    Xiaoyu Yu, Cong Cui, Jiyong He, Xiaoyu Guan, Zhe Zhang · 2026 · Frontiers in Cardiovascular Medicine
  23. Metabolic and Anti-Inflammatory Effects of Berberine—Rationale for Its Therapeutic Potential in Polycystic Ovary Syndrome
    Dariusz Szukiewicz · 2026 · International Journal of Molecular Sciences
  24. AMPK Therapy—A Little Goes A Long Way
    HANNAH M. CEBALLOS, Zhang Eryun, Wendong Huang · 2026 · Cells
  25. Berberine from Traditional Chinese Medicine in Liver Diseases: From Steatosis to Fibrosis and Hepatic Malignancies
    Hongxia He, Shuyun Wu, Jiazhi Yi · 2026 · The American Journal of Chinese Medicine
  26. Berberine and its derivatives as candidate modulators of immunosenescence: a critical evaluation
    Roman A. Zinovkin, Konstantin G. Lyamzaev, Alexey Viktorovich Churov, Olga Maltseva, Zhenghi Wu · 2026 · Biogerontology
  27. Indian Knowledge Systems (IKS) in Cardiovascular Sciences, Radiology and Medical Imaging, and Life Sciences
    Syed Nazar Raza, Naziya Yasmin · 2026
  28. Carrier-free supramolecular co-assembly enables oxygen-economizing photodynamic therapy via mitochondrial respiration suppression
    Xin Xie, Tao Quan, Haiqian Zhang, Rui Liang, Yong Huang, Lihe Sun, Fengmin Xiu, Biao Zheng, Zhou Shangjun, Chaohui Zhen et al. · 2026 · Journal of Nanobiotechnology
  29. Network Pharmacology-Guided Phytochemical Polypharmacology: Integrating Molecular Mechanisms, Experimental Validation and Clinical Translation
    Saahil A. Singh, Prabodh Wankhade, Rajesh Godvarthi, Rupesh Warbhe, Prashanth Khartade, Mohd Basheeruddin, Shilpa Narwade · 2026 · International Journal of Molecular Sciences
  30. Berberine as a multi-hallmark modulator of aging: From AMPK and mitophagy to inflammaging and the SASP
    Sultan Mohammed Alanazi, Hayder M. Al‐kuraishy, Ahmed M Abdelaziz, Eidah M. Alasmari, Fatimah Mohammadali Yousef, Ahmed A. Mohamed, Mohamed Mamdouh Salama, Gaber El‐Saber Batiha · 2026 · Fitoterapia
  31. Saccharopine and α-Aminoadipic Acid as Potential Biomarkers for Mitochondrial Stress in Neurons
    Anna‐Katharina Ückert, Anja Land, Regina Pape, Mahshid Alimohammadi, Ivano Amelio, Marcel Leist · 2026 · Cells
  32. Combination Therapy Potential of HTD1801 (Berberine Ursodeoxycholate) in MASLD/MASH and Cardiovascular–Kidney–Metabolic Disease: A Narrative Review
    Boknyun Kim, Joseph Kim, Grace Kim, Kitai Kim · 2026 · Pharmaceuticals
  33. Glucosamine and selenium differentially regulate glutathione, lipid peroxidation, and mitochondrial function during glutamate stress in retinal neural cells
    Ying-Jen Chen, Yuan‐Yuei Chen, Shuting Liu, Chen-Jung Wu, Yi-Lin Chiu · 2026 · Free Radical Biology and Medicine
  34. Berberine as a Mitochondrial Metabolic Reprogrammer in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Adaptive Energetic Stress, Quality Control, and Translational Limitations
    Hossein Rafiei, Kosar Omidian, Miguel Tolentino, Ali Jafari, Hossein Bahari, Mousa Khalafi · 2026 · Nutrients
  35. KELUARGA LIANA
    Nanik Siti Aminah, Alfinda Novi Kristanti, Rico Ramadhan, Rimuljo Hendradi, Heri Santoso, Geraldo Figo Hariyanto, Axl Laurens Lucas Windah, Zainab Kasenya Selemani, Muhammad Ikhlas Abdjan, Anandya Widya Nur Amanah et al. · 2026 · Airlangga University Press eBooks
  36. BindingDB Entry 50001409: Design, synthesis and biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3',2':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5'-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes.
    BindingDB · 2020 · UC San Diego
  37. BindingDB Entry 50045373: Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases.
    BindingDB · 2016 · UC San Diego
  38. BindingDB Entry 50015619: An insight into the medicinal attributes of berberine derivatives: A review.
    BindingDB · 2023 · UC San Diego
  39. BindingDB Entry 50018639: Natural products and analogs as preventive agents for metabolic syndrome via peroxisome proliferator-activated receptors: An overview.
    BindingDB · 2024 · UC San Diego
  40. Multidisciplinary Research: New Horizons, Emerging Trends and Contemporary Perspectives
    R.Dharma Ragini, M. Priya, Dr. Soniya K, K K Sanitha · 2026
  41. Selected Dietary and Supplemental Phytochemicals in Adiposity-Based Chronic Disease: Molecular Mechanisms, Human Evidence, and Translational Gaps
    Arguiñe Ivonne Urraza-Robledo, Edmar de Jésús Díaz García, Ibzan Jahzeel Salvador-Ibarra, Zoila Mora Guzmán, A.J. Borrás-Enríquez, Eduardo Pérez‐Campos, Laura Perez-Campos Mayoral, Daniel Gómez Hernández, María del Socorro Pina-Canseco, Héctor A. Cabrera-Fuentes et al. · 2026 · Nutrients