Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I

Cited by (541)

Items 201–300 of 541

  1. A novel formula Sang-Tong-Jian improves glycometabolism and ameliorates insulin resistance by activating PI3K/AKT pathway in type 2 diabetic KKAy mice
    Meiyu Kuai, Yu Li, Xin Sun, Zhi Ma, Chao Lin, Jing Yi, Ying Lu, Qi Chen, Xiang Wu, Xueyun Kong et al. · 2016 · Biomedicine & Pharmacotherapy
  2. The adiponectin signalling pathway - A therapeutic target for the cardiac complications of type 2 diabetes?
    Abhipree Sharma, Michael Mah, Rebecca Helen Ritchie, Miles J. De Blasio · 2021 · Pharmacology & Therapeutics
  3. Killing three birds with one stone: Multi-stage metabolic regulation mediated by clinically usable berberine liposome to overcome photodynamic immunotherapy resistance
    Chunjuan Zheng, Wenjuan Luo, Yu Liu, Jiashe Chen, Hui Deng, Zaigang Zhou, Jianliang Shen · 2022 · Chemical Engineering Journal
  4. A Mechanistic Review on How Berberine Use Combats Diabetes and Related Complications: Molecular, Cellular, and Metabolic Effects
    Vahid Reza Askari, Kimia Khosravi, Vafa Baradaran Rahimi, Stefanıa Garzoli · 2023 · Pharmaceuticals
  5. Screening for the efficacy on lipid accumulation in 3T3-L1 cells is an effective tool for the identification of new anti-diabetic compounds
    Xiao‐Yi Zeng, Xiu Zhou, Jun Xu, Stanley M. H. Chan, Charlie Changli Xue, Juan Carlos Molero, Ji‐Ming Ye · 2012 · Biochemical Pharmacology
  6. Regulation of hepatic cholesterol biosynthesis by berberine during hyperhomocysteinemia
    Nan Wu, Lindsei K. Sarna, Yaw Loong Siow, O Karmin · 2010 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  7. Dodecyl-TPP Targets Mitochondria and Potently Eradicates Cancer Stem Cells (CSCs): Synergy With FDA-Approved Drugs and Natural Compounds (Vitamin C and Berberine)
    Ernestina Marianna De Francesco, Béla Ózsvári, Federica Sotgia, Michael P. Lisanti · 2019 · Frontiers in Oncology
  8. Berberine attenuates cAMP-induced lipolysis via reducing the inhibition of phosphodiesterase in 3T3-L1 adipocytes
    Libin Zhou, Xiao Wang, Ying Yang, Ling Wu, Fengying Li, Rong Zhang, Guoyue Yuan, Ning Wang, Ming‐Dao Chen, Guang Ning · 2010 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  9. Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
    Kristensen, Jonas M., Larsen, Steen, Helge, Jørn W., Dela, Flemming, Wojtaszewski, Jørgen F. P. · 2013 · PLoS ONE
  10. Tetrahydroberberrubine retards heart aging in mice by promoting PHB2-mediated mitophagy
    Lei Wang, Xueqing Tang, Yang Shi, Huimin Li, Ziyu Meng, Hui Chen, Xiaohan Li, Yongchao Chen, Heng Liu, Yang Hong et al. · 2022 · Acta Pharmacologica Sinica
  11. Atrogin-1 Affects Muscle Protein Synthesis and Degradation When Energy Metabolism Is Impaired by the Antidiabetes Drug Berberine
    Huiling Wang, Dajun Liu, Peirang Cao, Stewart H. Lecker, Zhaoyong Hu · 2010 · Diabetes
  12. Berberine Up-Regulates Hepatic Low-Density Lipoprotein Receptor through Ras-Independent but AMP-Activated Protein Kinase-Dependent Raf-1 Activation
    Zheng Li, Jian‐Dong Jiang, Weijia Kong · 2014 · Biological and Pharmaceutical Bulletin
  13. Metabolic and cardiovascular effects of berberine: from preclinical evidences to clinical trial results
    Arrigo F.G. Cicero, Sibel Ertek · 2009 · Clinical Lipidology
  14. Berberine promotes ischemia-induced angiogenesis in mice heart via upregulation of microRNA-29b
    Mo‐Li Zhu, Yaling Yin, Ping Song, YU Hai-ya, Guang‐Rui Wan, Jian Chu Xu, Peng Li · 2017 · Clinical and Experimental Hypertension
  15. Mitochondrial Inhibitor as a New Class of Insulin Sensitizer
    Zhang, Yong, Ye, Jianping · 2012 · Acta Pharmaceutica Sinica B
  16. Berberine activates AMPK to suppress proteolytic processing, nuclear translocation and target DNA binding of SREBP-1c in 3T3-L1 adipocytes
    Jaewoong Jang, Yoonju Jung, Seong Jun Seo, Seok‐min Kim, Yae Jie Shim, Soo Hyun Cho, Sang‐In Chung, Yoosik Yoon · 2017 · Molecular Medicine Reports
  17. Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways
    Jia Li, Kuijin Xue, Junheng Liu, Ola A. Habotta, Lianhai Hu, Ahmed Esmat Abdel Moneim, Daniela Caccamo · 2020 · Mediators of Inflammation
  18. Efficacy and underlying mechanisms of berberine against lipid metabolic diseases: a review
    Yajie Cai, Qiaoning Yang, Yanqiao Yu, Furong Yang, Ruina Bai, Xiaodi Fan · 2023 · Frontiers in Pharmacology
  19. Improving insulin resistance with traditional Chinese medicine in type 2 diabetic patients
    Menglei Chao, Dajin Zou, Yifei Zhang, Yuhong Chen, Miao Wang, Hong Yang Wu, Guang Ning, Weiqing Wang · 2009 · Endocrine
  20. Natural activators of adenosine 5′-monophosphate (AMP)-activated protein kinase (AMPK) and their pharmacological activities
    Mahdi Vazirian, Seyed Mohammad Nabavi, Samineh Jafari, Azadeh Manayi · 2018 · Food and Chemical Toxicology
  21. AMPK in microvascular complications of diabetes and the beneficial effects of AMPK activators from plants
    Shrikanth Chomanahalli Basavarajappa, C. Nandini · 2018 · Phytomedicine
  22. Berberine reduces endoplasmic reticulum stress and improves insulin signal transduction in Hep G2 cells
    Zeng-si Wang, Fuer Lu, Lijun Xu, Hui Dong · 2010 · Acta Pharmacologica Sinica
  23. Berberine and cinnamaldehyde together prevent lung carcinogenesis
    Mingjing Meng, Shengnan Geng, Zhenhua Du, Jingjing Yao, Yaqiu Zheng, Zibo Li, Zhenzhen Zhang, Jiahuan Li, Yongjian Duan, Gangjun Du · 2017 · Oncotarget · Retracted
  24. Pharmacokinetic properties, potential herb–drug interactions and acute toxicity of oralRhizoma coptidisalkaloids
    Bing‐Liang Ma, Yueming Ma · 2012 · Expert Opinion on Drug Metabolism & Toxicology
  25. Hypoglycemic Activity and the Potential Mechanism of the Flavonoid Rich Extract from Sophora tonkinensis Gagnep. in KK-Ay Mice
    Mi Ni Huang, Shihao Deng, Qian-Qian Han, Ping Zhao, Qi Zhou, Sijian Zheng, Xinhua Ma, Chan Xu, Jing Yang, Xinzhou Yang · 2016 · Frontiers in Pharmacology
  26. Berberine augments ATP-induced inflammasome activation in macrophages by enhancing AMPK signaling
    Chenguang Li, Yan Liang, Yan-Yun Jing, Lihui Xu, Yidan Liang, Hongxia Wei, Bo Hu, Hao Pan, Qingbing Zha, Dong‐Yun Ouyang et al. · 2016 · Oncotarget
  27. Berberine: A Promising Natural Isoquinoline Alkaloid for the Development of Hypolipidemic Drugs
    Dong‐Dong Li, Pan Yu, Wei Xiao, Zhenzhong Wang, Lin-Guo Zhao · 2020 · Current Topics in Medicinal Chemistry
  28. Perspective: Prospects for Nutraceutical Support of Intestinal Barrier Function
    Mark Frederick McCarty, Aaron Lerner · 2020 · Advances in Nutrition
  29. Update on Berberine in Nonalcoholic Fatty Liver Disease
    Yang Liu, Li Rita Zhang, Haiyan Song, Guang Ji · 2013 · Evidence-based Complementary and Alternative Medicine
  30. Anti-inflammatory activity of berberine in non-alcoholic fatty liver disease via the Angptl2 pathway
    Lu, Zengsheng, He, Beihui, Chen, Zhiyun, Yan, Maoxiang, Wu, Liyan · 2020 · BMC Immunology
  31. Bouchardatine analogue alleviates non‐alcoholic hepatic fatty liver disease/non‐alcoholic steatohepatitis in high‐fat fed mice by inhibiting ATP synthase activity
    Yong Rao, Yuting Lu, Chan Li, Qinqin Song, Yao‐Hao Xu, Xu Dong Zhao, Yu‐Tao Hu, Hong Yu, Lin Gao, Lian‐Quan Gu et al. · 2019 · British Journal of Pharmacology
  32. Dihydroberberine, a hydrogenated derivative of berberine firstly identified in Phellodendri Chinese Cortex, exerts anti-inflammatory effect via dual modulation of NF-κB and MAPK signaling pathways
    Lihua Tan, Yongfu Wang, Gaoxiang Ai, Chaodan Luo, Hanbin Chen, Cailan Li, Huifang Zeng, Jianhui Xie, Jiannan Chen, Ziren Su · 2019 · International Immunopharmacology
  33. A natural product solution to aging and aging-associated diseases
    Chuanbin Yang, Wei Zhang, Xiaoduo Dong, Chunjin Fu, Jimin Yuan, Menglong Xu, Zhen Chang Liang, Chen Qiu, Chengchao Xu · 2020 · Pharmacology & Therapeutics
  34. Anti-aging properties of phytoconstituents and phyto-nanoemulsions and their application in managing aging-related diseases
    Feng Xue, Xuan Li, Linxi Qin, Xinye Liu, Chen Li, Benu Adhikari · 2021 · Advanced Drug Delivery Reviews
  35. Berberine combined with 2-deoxy-d-glucose synergistically enhances cancer cell proliferation inhibition via energy depletion and unfolded protein response disruption
    Li-xia Fan, Chang‐Mei Liu, Anhui Gao, Yubo Zhou, Jia Xuan Li · 2013 · Biochimica et Biophysica Acta (BBA) - General Subjects
  36. Berberine derivatives reduce atherosclerotic plaque size and vulnerability in apoE−/− mice
    Junwen Chen, Jiatian Cao, Fang Ying Lu, Bo Liu, Qing Zhou, Yinggang Sun, Yue Wang, Yi‐Gang Li, Shu Meng · 2014 · Journal of Translational Medicine
  37. Novel carbohydrate modified berberine derivatives: synthesis and in vitro anti-diabetic investigation
    Liwen Han, Wenlong Sheng, Xiaobin Li, Attila Gabor SIK, Hou‐Wen Lin, Kechun Liu, Lizhen Wang · 2019 · MedChemComm
  38. Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review
    Noriko Shinjyo, James R.C. Parkinson, Jimmy David Bell, Tatsuro Katsuno, S. W. Annie Bligh · 2020 · Journal of Chinese Integrative Medicine
  39. Effects of dietary berberine hydrochloride inclusion on growth, antioxidant capacity, glucose metabolism and intestinal microbiome of largemouth bass (Micropterus salmoides)
    Shiwen Chen, Xueluan Jiang, Ning Liu, Minchun Ren, Zhenjie Wang, Mingkong Li, Naisong Chen, Songlin Li · 2022 · Aquaculture
  40. Approaching strategy to increase the oral bioavailability of berberine, a quaternary ammonium isoquinoline alkaloid: Part 1. Physicochemical and pharmacokinetic properties
    Murakami, Teruo, Bodor, Erik, Bodor, Nicholas · 2023 · Expert Opinion on Drug Metabolism & Toxicology
  41. Berberine attenuates the abnormal ectopic lipid deposition in skeletal muscle
    Yao, Shuangshuang, Yuan, Yini, Zhang, Huizhi, Meng, Xiangjian, Jin, Lina, Yang, Jian, Wang, Weiqing, Ning, Guang, Zhang, Yifei, Zhang, Zhiguo · 2020 · Free Radical Biology and Medicine
  42. Azoxystrobin, a mitochondrial complex III Qo site inhibitor, exerts beneficial metabolic effects in vivo and in vitro
    Anhui Gao, Yanyun Fu, Kunzhi Zhang, Mei Zhang, Haowen Jiang, Li-Xia Fan, Fajun Nan, Chonggang Yuan, Jia Xuan Li, Yubo Zhou et al. · 2014 · Biochimica et Biophysica Acta (BBA) - General Subjects
  43. Phenolic Secoiridoids in Extra Virgin Olive Oil Impede Fibrogenic and Oncogenic Epithelial-to-Mesenchymal Transition: Extra Virgin Olive Oil As a Source of Novel Antiaging Phytochemicals
    Alejandro Vázquez‐Martín, Salvador Fernández‐Arroyo, Sílvia Cufí, Cristina Oliveras‐Ferraros, Jesús Lozano‐Sánchez, Luciano Vellón, Vicente Micol, Jorge Joven, Antonio Segura‐Carretero, Javier Abel Menéndez · 2012 · Rejuvenation Research
  44. Targeting AMPK: From Ancient Drugs to New Small-Molecule Activators
    Bruno Guigas, Benoı̂t Viollet · 2016 · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions
  45. Berberine Protects Human Retinal Pigment Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Damage through Activation of AMPK
    Shuai Li, Uma Gaur, Cheong‐Meng Chong, Shaofen Lin, Jiankang Fang, Zhiwen Zeng, Haitao Wang, Wenhua Zheng · 2018 · International Journal of Molecular Sciences
  46. The Role of the Interplay Between Autophagy and NLRP3 Inflammasome in Metabolic Disorders
    Shuangyu Lv, Honggang Wang, Xiaotian Li · 2021 · Frontiers in Cell and Developmental Biology
  47. Unlocking the potential of Berberine: Advancing cancer therapy through chemosensitization and combination treatments
    Anjana Sajeev, Bethsebie Sailo, Jyothsna Unnikrishnan, Ayesha Talukdar, Mohammed Saeed Alqahtani, Mohamed Abd Elhamid Abbas, Athba Alqahtani, Gautam Sethi, Ajaikumar Bahulayan Kunnumakkara · 2024 · Cancer Letters
  48. Mitochondrial-cytochrome c oxidase II promotes glutaminolysis to sustain tumor cell survival upon glucose deprivation
    Yong Yi, Guoqiang Wang, Wenhua Zhang, Shuhan Yu, Junjie Fei, Tingting An, Jianqiao Yi, Fengtian Li, Ting Huang, Jun Yang et al. · 2025 · Nature Communications
  49. Inhibition of Polo-like Kinase 1 (Plk1) Enhances the Antineoplastic Activity of Metformin in Prostate Cancer
    Chen Shao, Nihal Ahmad, Kurt B. Hodges, Shihuan Kuang, Tim Ratliff, Xiaoqi Liu · 2014 · Journal of Biological Chemistry
  50. Nutraceutical, Dietary, and Lifestyle Options for Prevention and Treatment of Ventricular Hypertrophy and Heart Failure
    Mark Frederick McCarty · 2021 · International Journal of Molecular Sciences
  51. Berberine Alleviates Insulin Resistance and Inflammation via Inhibiting the LTB4–BLT1 Axis
    Minmin Gong, Huiyan Duan, Fan Wu, Yanlin Ren, Jing Gong, Lijun Xu, Fuer Lu, Dingkun Wang · 2021 · Frontiers in Pharmacology
  52. Targeting the liver kinase B1/AMP-activated protein kinase pathway as a therapeutic strategy for hematological malignancies
    Alberto Maria Martelli, Francesca Chiarini, Camilla Evangelisti, Andrea Ognibene, Daniela Bressanin, Anna Maria Billi, Lucia Manzoli, Alessandra Cappellini, James Andrew McCubrey · 2012 · Expert Opinion on Therapeutic Targets
  53. Comparative pharmacokinetics and safety assessment of transdermal berberine and dihydroberberine
    Beth Buchanan, Qingfang Meng, Mathieu-Marc Poulin, Jonathan Zuccolo, Chike Godwin Azike, Joseph P. Gabriele, David Charles Baranowski · 2018 · PLoS ONE
  54. Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity
    Katharina Timper, Lars Paeger, Carmen Sánchez-Lasheras, Luis Varela, Alexander Jaïs, Hendrik Nolte, Merly C. Vogt, Anne Christine Hausen, Christian Heilinger, Nadine Evers et al. · 2018 · Cell Reports
  55. Synthesis of disaccharide modified berberine derivatives and their anti-diabetic investigation in zebrafish using a fluorescence-based technology
    Lizhen Wang, Haotian Kong, Meng Jin, Xiaobin Li, Rostyslav S. Stoika, Hou‐Wen Lin, Kechun Liu · 2020 · Organic & Biomolecular Chemistry
  56. Melatonin-based therapeutics for atherosclerotic lesions and beyond: Focusing on macrophage mitophagy
    Amir Ajoolabady, Yaguang Bi, David Julian McClements, Gregory Y.H. Lip, Des Raymond Richardson, Russel Joseph Reiter, Daniel J. Klionsky, Jun Tao Ren · 2022 · Pharmacological Research
  57. Rhizoma Anemarrhenae extract ameliorates hyperglycemia and insulin resistance via activation of AMP-activated protein kinase in diabetic rodents
    Han, Jun, Yang, Na, Zhang, Feng, Zhang, Chuan, Liang, Fengying, Xie, WeiFen, Chen, Wansheng · 2015 · Journal of Ethnopharmacology
  58. Berberine Induces Mitophagy through Adenosine Monophosphate-Activated Protein Kinase and Ameliorates Mitochondrial Dysfunction in PINK1 Knockout Mouse Embryonic Fibroblasts
    Jee‐Hyun Um, Kang‐Min Lee, Young-Yeon Kim, Da‐Ye Lee, Eun-Mi Kim, Donghyun Kim, Jeanho Yun · 2023 · International Journal of Molecular Sciences
  59. Berberine is a potential therapeutic agent for metabolic syndrome via brown adipose tissue activation and metabolism regulation.
    Xiaofei Hu, Yaqi Zhang, Yuan Xue, Zhuoli Zhang, Jian Wang · 2018 · Europe PMC (PubMed Central)
  60. The Effect of Berberine on Reproduction and Metabolism in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Control Trials
    Liangzhen Xie, Duojia Zhang, Hongli Ma, Hui Rong He, Qing Xia, Wenjuan Shen, Hui Chang, Yingying Deng, Qi Wu, Jing Cong et al. · 2019 · Evidence-based Complementary and Alternative Medicine
  61. NNMT‐DNMT1 Axis is Essential for Maintaining Cancer Cell Sensitivity to Oxidative Phosphorylation Inhibition
    Changqing Wu, Yue Liu, Wenju Liu, Tianhui Zou, Shaojuan Lu, Chengjie Zhu, Le He, Jie Chen, Lan Fang, Lin Zou et al. · 2022 · Advanced Science
  62. Berberis Fruit Extract and Biochemical Parameters in Patients With Type II Diabetes
    Zoleika Moazezi, Durdi Qujeq · 2014 · Jundishapur Journal of Natural Pharmaceutical Products
  63. Berberine Regulated Gck, G6pc, Pck1 and Srebp-1c Expression and Activated AMP-activated Protein Kinase in Primary Rat Hepatocytes
    Yuebin Ge, Yan Zhang, Rui Li, Wei Chen, Yang Li, Guoxun Chen · 2011 · International Journal of Biological Sciences
  64. The anti-hyperglycemia effects of Rhizoma Coptidis alkaloids: A systematic review of modern pharmacological studies of the traditional herbal medicine
    Ma, Hang, He, Kai, Zhu, Jianwei, Li, Xuegang, Ye, Xiaoli · 2019 · Fitoterapia
  65. Tetrahydroberberrubine attenuates lipopolysaccharide-induced acute lung injury by down-regulating MAPK, AKT, and NF-κB signaling pathways
    Xiu Yu, Sulan Yu, Ling Chen, Han Liu, Jiän Zhang, Haixia Ge, Yuanyuan Zhang, Boyang Yu, Junping Kou · 2016 · Biomedicine & Pharmacotherapy
  66. The Interplay of AMP-Activated Protein Kinase and Androgen Receptor in Prostate Cancer Cells
    Min Shen, Zhen Zhang, Manohar Ratnam, Q. Ping Dou · 2013 · Journal of Cellular Physiology
  67. The Preconditioning of Berberine Suppresses Hydrogen Peroxide‐Induced Premature Senescence via Regulation of Sirtuin 1
    Xiaofei Zhu, Haodi Yue, Xiaofang Guo, Jingyi Yang, Jingshuo Liu, Jiangtao Liu, Ruijie Wang, Wenjuan Zhu · 2017 · Oxidative Medicine and Cellular Longevity
  68. Berberine reduces endothelial injury and arterial stiffness in spontaneously hypertensive rats
    Gaoxing Zhang, Xiufang Lin, Yijia Shao, Chen Su, Jun Tao, Xing Liu · 2019 · Clinical and Experimental Hypertension
  69. A novel chemical uncoupler ameliorates obesity and related phenotypes in mice with diet-induced obesity by modulating energy expenditure and food intake
    Fu, Y.-Y., Zhang, M., Turner, N., Zhang, L.-N., Dong, T.-C., Gu, M., Leslie, S. J., Li, J.-Y., Nan, F.-J., Li, J. · 2013 · Diabetologia
  70. Targeting AMPK signaling in combating ovarian cancers: opportunities and challenges
    Mingo M. H. Yung, Hys Ngan, David W. Chan · 2016 · Acta Biochimica et Biophysica Sinica
  71. Network Pharmacology Analysis of Traditional Chinese Medicine Formula Xiao Ke Yin Shui Treating Type 2 Diabetes Mellitus
    Jiewen Zhou, Qiuyan Wang, Zhi-Nan Xiang, Qilin Tong, Jun Pan, Luo-Sheng Wan, Jiachun Chen · 2019 · Evidence-based Complementary and Alternative Medicine
  72. Alterations in Cellular Energy Metabolism Associated with the Antiproliferative Effects of the ATM Inhibitor KU-55933 and with Metformin
    Mahvash Zakikhani, Miguel Bazile, Sina Hashemi, Shiva Javeshghani, Daina Zofija Avizonis, Julie St‐Pierre, Michaël Pollak · 2012 · PLoS ONE
  73. Multipath effects of berberine on peach Brown rot fungus Monilinia fructicola
    Qinghui Pei, Ying Li, Xizhen Ge, Pingfang Tian · 2018 · Crop Protection
  74. Targeting Sirt1, AMPK, Nrf2, CK2, and Soluble Guanylate Cyclase with Nutraceuticals: A Practical Strategy for Preserving Bone Mass
    Mark Frederick McCarty, Lidianys María Lewis Luján, Simon Bernard Iloki Assanga · 2022 · International Journal of Molecular Sciences
  75. Shizukaol D Isolated from Chloranthus japonicas Inhibits AMPK-Dependent Lipid Content in Hepatic Cells by Inducing Mitochondrial Dysfunction
    Rongkuan Hu, Huan Yan, Xiao‐Jiang Hao, Hai‐Yang Liu, Jiarui Wu · 2013 · PLoS ONE
  76. 13-Methylberberine, a berberine analogue with stronger anti-adipogenic effects on mouse 3T3-L1 cells
    Yit‐Lai Chow, Mami Sogame, Fumihiko Sato · 2016 · Scientific Reports
  77. Berberine-microbiota interplay: orchestrating gut health through modulation of the gut microbiota and metabolic transformation into bioactive metabolites
    Dehau, Tessa, Cherlet, Marc, Croubels, Siska, Van De Vliet, Michiel, Goossens, Evy, Van Immerseel, Filip · 2023 · Frontiers in Pharmacology
  78. Large enhancement of skeletal muscle cell glucose uptake and suppression of hepatocyte glucose-6-phosphatase activity by weak uncouplers of oxidative phosphorylation
    Louis C. Martineau · 2011 · Biochimica et Biophysica Acta (BBA) - General Subjects
  79. Phosphoproteomics of Acute Cell Stressors Targeting Exercise Signaling Networks Reveal Drug Interactions Regulating Protein Secretion
    Elise J. Needham, Sean J. Humphrey, Kristen C. Cooke, Daniel J. Fazakerley, Xiaowen Duan, Benjamin L. Parker, David Ernest James · 2019 · Cell Reports
  80. Enhanced liver but not muscle OXPHOS in diabetes and reduced glucose output by complex I inhibition
    Miriayi Alimujiang, YU Xue-ying, Muyu Yu, Wolin Hou, Zhonghong Yan, Ying Yang, Yuqian Bao, Jun Yin · 2020 · Journal of Cellular and Molecular Medicine
  81. Berberine as a Potential Multi-Target Agent for Metabolic Diseases: A Review of Investigations for Berberine
    Shengju Wang, Xu Zhang, Baochao Cai, Qiu Chen · 2020 · Endocrine Metabolic & Immune Disorders - Drug Targets
  82. Strategies for the Discovery and Development of Anti-Diabetic Drugs from the Natural Products of Traditional Medicines
    Ji-Ming Ye, Stanley M.H. · 2013 · Journal of Pharmacy & Pharmaceutical Sciences
  83. Berberine exerts anti-adipogenic activity through up-regulation of C/EBP inhibitors, CHOP and DEC2
    Truc P.T. Pham, Jeongho Kwon, Jaekyoon Shin · 2011 · Biochemical and Biophysical Research Communications
  84. Non-alcoholic fatty pancreas disease – practices for clinicians
    Larisa Pinte, Daniel Vasile Balaban, Cristian Băicuş, Mariana Jinga · 2019 · Romanian Journal of Internal Medicine
  85. Antidiabetic activity of perylenequinonoid-rich extract from Shiraia bambusicola in KK-Ay mice with spontaneous type 2 diabetes mellitus
    Mi Ni Huang, Ping Zhao, Mingrui Xiong, Qi Zhou, Sijian Zheng, Xinhua Ma, Chan Xu, Jing Yang, Xinzhou Yang, Tongcun Zhang · 2016 · Journal of Ethnopharmacology
  86. Berberine attenuates fructose-induced insulin resistance by stimulating the hepatic LKB1/AMPK/PGC1α pathway in mice
    Yucheng Li, Baoying Wang, Ji-Duo Shen, Ming Bai, Erping Xu · 2020 · Pharmaceutical Biology
  87. Preconditioning mice with activators of AMPK ameliorates ischemic acute kidney injury in vivo
    Wilfred Lieberthal, Meiyi Tang, Mark A. Lusco, Mersema T. Abate, Jerrold S. Levine · 2016 · American Journal of Physiology-Renal Physiology
  88. Muscarinic Receptor Activation of AMP-activated Protein Kinase Inhibits Orexigenic Neuropeptide mRNA Expression
    Claire Thornton, Alessandro Sardini, David Carling · 2008 · Journal of Biological Chemistry
  89. Modulators of Hepatic Lipoprotein Metabolism Identified in a Search for Small-Molecule Inducers of Tribbles Pseudokinase 1 Expression
    M. Marek Nagiec, Adam P. Skepner, Joseph M. Negri, Michelle Eichhorn, Nicolas Kuperwasser, Eamon Comer, Giovanni Muncipinto, Aravind Subramanian, Clary B. Clish, Kiran Musunuru et al. · 2015 · PLoS ONE
  90. Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help?
    Francesco Visioli, Avery Ingram, Joseph S. Beckman, Kathy Ruth Magnusson, Tory M. Hagen · 2021 · Free Radical Biology and Medicine
  91. Berberine: metabolic and cardiovascular effects in preclinical and clinical trials
    Arrigo F.G. Cicero · 2009 · Nutrition and Dietary Supplements
  92. Berberine and evodiamine influence serotonin transporter (5-HTT) expression via the 5-HTT-linked polymorphic region
    Yueshan Hu, Erik A. Ehli, James J. Hudziak, Gareth E. Davies · 2011 · The Pharmacogenomics Journal
  93. Arctigenin alleviates ER stress via activating AMPK
    Yuan Jun Gu, Xiaoxiao Sun, Ji‐Ming Ye, Li He, Shou‐Sheng Yan, Haohao Zhang, Lihong Hu, Junying Yuan, Qiang Yu · 2012 · Acta Pharmacologica Sinica
  94. AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway
    Masayuki Morishita, Teruya Kawamoto, Hitomi Hara, Yasuo Onishi, Takeshi Ueha, Masaya Minoda, Etsuko Katayama, Toshiyuki Takemori, Naomasa Fukase, Masahiro Kurosaka et al. · 2016 · International Journal of Oncology
  95. Berberine-induced glucagon-like peptide-1 and its mechanism for controlling type 2 diabetes mellitus: a comprehensive pathway review
    Mostafa Araj‐Khodaei, Mohammad Hossein Ayati, Akbar Azizi-Zeinalhajlou, Tannaz Novinbahador, Mehdi Yousefi, Mahdi Shiri, Ata Mahmoodpoor, Ali Shamekh, Nazli Namazi, Sarvin Sanaie · 2023 · Archives of Physiology and Biochemistry
  96. AMPK activation—protean potential for boosting healthspan
    Mark Frederick McCarty · 2013 · AGE
  97. Targeting mitochondrial dysfunction for the treatment of diabetic complications: Pharmacological interventions through natural products
    Sadhana S. Sathaye, Aakruti Arun Kaikini, DivyaManohar Kanchan, UrviNarayan Nerurkar · 2017 · Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review
  98. Morus alba leaf extract stimulates 5′-AMP-activated protein kinase in isolated rat skeletal muscle
    Xiao Ma, Nobumasa Iwanaka, Shinya Masuda, Kouhei Karaike, Tatsuro Egawa, Taku Hamada, Tarō Toyoda, Licht Miyamoto, Kazuwa Nakao, Tatsuya Hayashi · 2008 · Journal of Ethnopharmacology
  99. Berberine stimulates fibroblast growth factor 21 by modulating the molecular clock component brain and muscle Arnt-like 1 in brown adipose tissue
    Takao Hirai, Yuhei Mitani, Karen Kurumisawa, Kohei Nomura, Wei Wang, Ken‐ichi Nakashima, Makoto Inoue · 2019 · Biochemical Pharmacology
  100. Effects of a standardized Ayurvedic formulation on diabetes control in newly diagnosed Type-2 diabetics; a randomized active controlled clinical study
    Harshika Awasthi, Rajendra Nath, Kauser Usman, Dayanandan Mani, Sanjay Khattri, Anuradha Nischal, Manju Singh, Kamal Kumar Sawlani · 2015 · Complementary Therapies in Medicine