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LXR activation ameliorates high glucose stress-induced aberrant mitochondrial dynamics via downregulation of Calpain1 expression in H9c2 cardiomyoblasts

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Rosiglitazone reduces diabetes angiopathy by inhibiting mitochondrial dysfunction dependent on regulating HSP22 expression

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Metformin Impedes Oxidation of LDL In Vitro

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Metformin in Glaucoma Treatment

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Pharmacological Activation of AMPK Prevents Drp1-mediated Mitochondrial Fission and Alleviates Hepatic Steatosis In vitro

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S ‐Allylcysteine Ameliorates Aging Features via Regulating Mitochondrial Dynamics in Naturally Aged C57BL/6J Mice

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Endothelial Metabolic Reprogramming Links Diabetes to Atherosclerosis

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Hydrogen Sulfide Diminishes Activation of Adventitial Fibroblasts Through the Inhibition of Mitochondrial Fission

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Liraglutide Counteracts Endoplasmic Reticulum Stress in Palmitate-Treated Hypothalamic Neurons without Restoring Mitochondrial Homeostasis

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Drp1 knockdown aggravates obesity-induced cardiac dysfunction and remodeling

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Metformin suppresses atherosclerosis by dampening extramedullary myelopoiesis

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DL ‐3‐n‐Butylphthalide Protects Mitochondria Against Ischemia/Hypoxia Damage via Suppressing GCN5L1 ‐Mediated Drp1 Acetylation in Neurons and Mouse Brains

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Metformin Inhibits Multiple Myeloma Serum-induced Endothelial Cell Thrombosis by Down-Regulating miR-532

Gao, L., Li, L., Hu, J., Li, G., Zhang, Y., Dai, X., De, Z., & Xu, F. (2022) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2022.04.035 · Cited by 6

Metformin Reduces the Progression of Atherogenesis by Regulating the Sestrin2-mTOR Pathway in Obese and Diabetic Rats

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Metformin promotes proliferation and suppresses apoptosis in Ox-LDL stimulated macrophages by regulating the miR-34a/Bcl2 axis

Feng, L., Liu, T., Yang, Y., Xiao, W., Shi, J., Mei, X., Tian, S., Liu, X., Huang, H., & Bai, Y. (2019) · RSC Advances · doi:10.1039/c9ra00705a · Cited by 6

Macrophage cannibalism: efferocytosis in atherosclerosis

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The role of heat shock protein B8 in neuronal protection against oxidative stress and mitochondrial dysfunction: A literature review

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Polyphenol extract ameliorates diabetes-related atherosclerosis through HIF-1 signaling pathway in APOE−/− mice: Possible synergism with atorvastatin

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Pioglitazone Ameliorates Mitochondrial Oxidative Stress and Inflammation via AMPK ‐Dependent Inhibition of Mitochondrial Fission in Leigh Syndrome

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Hydrogen ameliorates endotoxin-induced acute lung injury through AMPK-mediated bidirectional regulation of Caspase3

Li, Q., Shi, M., Ang, Y., Yu, P., Wan, B., Lin, B., Chen, W., Yue, Z., Shi, Y., Liu, F., et al. (2024) · Molecular Immunology · doi:10.1016/j.molimm.2024.02.001 · Cited by 5

Metformin inhibits cholesterol‑induced adhesion molecule expression via activating the AMPK signaling pathway in vascular smooth muscle cells

Liu, Q., Yang, M., Zhang, L., Zhang, R., Huang, X., Wang, X., Du, W., & Hou, J. (2021) · Molecular Medicine Reports · doi:10.3892/mmr.2021.12348 · Cited by 5

Decoding interaction between mitochondria and endoplasmic reticulum in ischemic myocardial injury: targeting natural medicines

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MSCs ameliorates hyperglycemia-induced endothelial injury through modulation of mitochondrial dynamics

Wei, J., Mao, R., Chen, Y., Si, K., Yao, L., Li, J., & Zhu, W. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-08175-x · Cited by 4

Mitochondrial dysfunction in hypertension: mechanistic pathways and therapeutic implications

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Upstream targeting for the prevention of atrial fibrillation: Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)—rationale and study design

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7′-Hydroxyl substituted xanthones from Gentianella acuta revert hepatic steatosis in obese diabetic mice through preserving mitochondrial homeostasis

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Prestroke Metformin Use on the 1‐Year Prognosis of Intracerebral Hemorrhage Patients with Type 2 Diabetes

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Cellular and Functional Effects of Insulin Based Therapies and Exercise on Endothelium

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Enhanced Mitochondrial Dynamics and Reactive Oxygen Species Levels with Reduced Antioxidant Defenses in Human Epicardial Adipose Tissue

Burgeiro, A., Santos, D., Fonseca, A. C. R. G., Baldeiras, I., Leal, E. C., Moura, J., Costa-Nunes, J., Seraphim, P. M., Pinho, A. C. O., Canotilho, A., et al. (2025) · Metabolites · doi:10.3390/metabo15070481 · Cited by 3

Metformin Attenuates Osteoarthritis Progression by Modulating Mitochondrial Dynamics via Activation of the AMPK/Drp1 Pathway

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Metformin as a multi-target modulator of atherosclerosis: integrated regulation of Nrf2/KLF2, mitochondrial homeostasis, inflammation, ferroptosis, and innate immunity

Alanazi, M., Al-Kuraishy, H. M., Mustafa, A. M., Alruwaili, M., Alexiou, A. T., Papadakis, M., & Batiha, G. E. (2026) · Journal of Pharmacy and Pharmacology · doi:10.1093/jpp/rgag056 · Cited by 2

Therapeutic Potential of Metformin in Diabetes Mellitus-Related Cardiovascular Complications

Tan, H., & Tao, J. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.108606 · Cited by 2

Metformin inhibited Nod-like receptor protein 3 inflammasomes activation and suppressed diabetes-accelerated atherosclerosis in apoE−/− mice

Tang, G., Duan, F., Li, W., Wang, Y., Zeng, C., Hu, J., Li, H., Zhang, X., Chen, Y., & Tan, H. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109410 · Cited by 70

Metformin Delays the Development of Atherosclerosis in Type 1 Diabetes Mellitus via the Methylglyoxal Pathway

Liu, A., Li, K., Xu, L., Si, M., Teng, G., Li, G., Xue, J., Liang, S., & Song, W. (2020) · Diabetes Therapy · doi:10.1007/s13300-020-00761-w · Cited by 12

Metformin directly suppresses atherosclerosis in normoglycaemic mice via haematopoietic adenosine monophosphate-activated protein kinase

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