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Cited by 66Diabetic Foot Ulcer Assessment and ManagementWound Healing and TreatmentsSurgical site infection prevention

New Evidence-Based Therapies for Complex Diabetic Foot Wounds

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Boulton, Andrew, Armstrong, David, Londahl, Magnus, Frykberg, Robert, Game, Frances, Edmonds, Michael, Orgill, Dennis, Kramer, Kimberly +3 more·2022·ADA Clinical Compendia
DOI 10.2337/db2022-02
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Abstract

This treatise includes reviews of both of these new therapies by members of our author group (F.L.G. and M.E.E.) who participated in the clinical trials of the respective agents. Additionally, the use of negative pressure wound therapy (NPWT), which is also supported by evidence from RCTs, is reviewed. The final two sections of this compendium explore putative new, evidence-based therapies for DFUs that are in the pipeline and, most importantly, how we might engage digital technology and other aids to facilitate the prevention of DFU recurrence.

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  • Many patients with diabetic foot ulcers have some degree of nutritional deficit.

    “Many patients with diabetic foot ulcers have some degree of nutritional deficit.90”

    From Diabetic Foot Ulcers (2023) · cites this paper as [90]

    The Negative Pressure Wound Therapy section describes patients with diabetic foot ulcers as often having obesity and other comorbidities, but does not discuss nutritional deficits. Searches of our copy for nutritional deficit, malnutrition, and nutritional status found no passage addressing how common nutritional deficits are in these patients. Page numbers were not available in the indexed copy. (LLM, conf=0.74)

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Research works printed but not linked: 33

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  2. Birch SB. Some remarks on the exhibition of oxygen as a therapeutic, in connexion with a new, agreeable, and easy form of administration by the stomach. Lancet 1869;93:492-493
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Authors
Boulton, A., Armstrong, D., Londahl, M., Frykberg, R., Game, F., Edmonds, M., Orgill, D., Kramer, K., Gurtner, G., Januszyk, M., & Vileikyte, L.
Affiliations
  • University of Miami (US)
  • University of Southern California (US)
  • University Hospitals of Derby and Burton NHS Foundation Trust (GB)
  • King's College Hospital (GB)
  • Brigham and Women's Hospital (US)
  • Stanford Medicine (US)
Corresponding author
  • Boulton, Andrew
  • Armstrong, David
ORCID
Venue
ADA Clinical Compendia
Publisher
American Diabetes Association
Published
2022
Volume
2022
Issue
2
Pages
1-23
ISSN
  • 2771-6872 (ISSN-L)
  • 2771-6880
DOI
10.2337/db2022-02
OpenAlex
W4296474055
Cited by
66
References
41
Citations by year
2026: 8 · 2025: 22 · 2024: 22 · 2023: 11 · 2022: 3
FWCI
10.75
Type
journal article
Language
en
Open access
Licence
cc-by-nc-nd
Locations
ADA Clinical Compendia (publishedVersion, cc-by-nc-nd)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetic Foot Ulcer Assessment and Management
  • Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
  • Health Sciences › Medicine › Surgery › Surgical site infection prevention
Keywords
diabetic foot ulcer, negative pressure wound therapy, wound healing therapy, digital health technologies, evidence-based treatment

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