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Cited by 1,465Physical Activity and HealthDiabetes, Cardiovascular Risks, and LipoproteinsObesity, Physical Activity, Diet

The DOI matches its Crossref record, with a small difference in title or year; 34 of the 34 references it cites were found in a registry or an index.

Breaks in Sedentary Time

Open access
Healy, Genevieve N., Dunstan, David W., Salmon, Jo, Cerin, Ester, Shaw, Jonathan E., Zimmet, Paul Z., Owen, Neville·2008·Diabetes Care
DOI 10.2337/dc07-2046
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Abstract

OBJECTIVE—Total sedentary (absence of whole-body movement) time is associated with obesity, abnormal glucose metabolism, and the metabolic syndrome. In addition to the effects of total sedentary time, the manner in which it is accumulated may also be important. We examined the association of breaks in objectively measured sedentary time with biological markers of metabolic risk. RESEARCH DESIGN AND METHODS—Participants (n = 168, mean age 53.4 years) for this cross-sectional study were recruited from the 2004–2005 Australian Diabetes, Obesity and Lifestyle study. Sedentary time was measured by an accelerometer (counts/minute−1 < 100) worn during waking hours for seven consecutive days. Each interruption in sedentary time (counts/min ≥100) was considered a break. Fasting plasma glucose, 2-h plasma glucose, serum triglycerides, HDL cholesterol, weight, height, waist circumference, and resting blood pressure were measured. MatLab was used to derive the breaks variable; SPSS was used for the statistical analysis. RESULTS—Independent of total sedentary time and moderate-to-vigorous intensity activity time, increased breaks in sedentary time were beneficially associated with waist circumference (standardized β = −0.16, 95% CI −0.31 to −0.02, P = 0.026), BMI (β = −0.19, −0.35 to −0.02, P = 0.026), triglycerides (β = −0.18, −0.34 to −0.02, P = 0.029), and 2-h plasma glucose (β = −0.18, −0.34 to −0.02, P = 0.025). CONCLUSIONS—This study provides evidence of the importance of avoiding prolonged uninterrupted periods of sedentary (primarily sitting) time. These findings suggest new public health recommendations regarding breaking up sedentary time that are complementary to those for physical activity.

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Metadata

Authors
Healy, G. N., Dunstan, D. W., Salmon, J., Cerin, E., Shaw, J. E., Zimmet, P. Z., & Owen, N.
Affiliations
  • The University of Queensland (AU)
  • International Diabetes Institute, Melbourne, Australia
  • Deakin University (AU)
  • University of Hong Kong (HK)
ORCID
Venue
Diabetes Care
Publisher
American Diabetes Association
Published
2008-04-01
Volume
31
Issue
4
Pages
661-666
ISSN
  • 0149-5992 (ISSN-L)
  • 1935-5548
DOI
10.2337/dc07-2046
OpenAlex
W2143931350
Cited by
1,465
References
34
Citations by year
2026: 28 · 2025: 37 · 2024: 49 · 2023: 56 · 2022: 47 · 2021: 84 · 2020: 86 · 2019: 98 · 2018: 105 · 2017: 135 · 2016: 133 · 2015: 144 · 2014: 105 · 2013: 113 · 2012: 87
FWCI
35.54
Type
journal article
Language
en
Open access
Locations
  • Diabetes Care (publishedVersion)
  • PubMed (publishedVersion)
  • eSpace (Curtin University) (submittedVersion)
  • The HKU Scholars Hub (University of Hong Kong) (submittedVersion)
Funders
National Health and Medical Research Council (233200, 301200)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Keywords
sedentary behavior, sitting time, metabolic risk, waist circumference, body mass index, triglycerides, fasting blood glucose, 2-hour plasma glucose, metabolic syndrome, obesity, physical activity, accelerometer-measured sedentary time
MeSH terms
Adult, Aged, Aged, 80 and over, Australia, Blood Glucose, Cardiovascular Diseases, Cross-Sectional Studies, Diabetes Mellitus, Diabetic Angiopathies, Diabetic Nephropathies, Humans, Life Style, Middle Aged, Motor Activity, Obesity, Rest, Risk Factors, Time Factors, Triglycerides, Work, Body Size

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