Factors associated with diabetes-specific health-related quality of life in youth with type 1 diabetes: the Global TEENs Study
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OBJECTIVE Our objective was to characterize diabetes-specific health-related quality of life (D-HRQOL) in a global sample of youth and young adults with type 1 diabetes (T1D) and to identify the main factors associated with quality of life. RESEARCH DESIGN AND METHODS The TEENs study was an international, cross-sectional study of youth, 8–25 years of age, with T1D. Participants (N = 5,887) were seen in clinical sites in 20 countries across 5 continents enrolled for 3 predetermined age groups: 8–12, 13–18, and 19–25 years of age. To assess D-HRQOL, participants completed the PedsQL Diabetes Module 3.0 and were interviewed about family-related factors. Specifics about treatment regimen and self-management behaviors were collected from medical records. RESULTS Across all age groups, females reported significantly lower D-HRQOL than did males. The 19–25-year age group reported the lowest D-HRQOL. Multivariate linear regression analyses revealed that D-HRQOL was significantly related to HbA1c; the lower the HbA1c, the better the D-HRQOL. Three diabetes-management behaviors were significantly related to better D-HRQOL: advanced methods used to measure food intake; more frequent daily blood glucose monitoring; and more days per week that youth had ≥30 min of physical activity. CONCLUSIONS In all three age groups, the lower the HbA1c, the better the D-HRQOL, underscoring the strong association between better D-HRQOL and optimal glycemic control in a global sample of youth and young adults. Three diabetes-management behaviors were also related to optimal glycemic control, which represent potentially modifiable factors for clinical interventions to improve D-HRQOL as well as glycemic control.
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Youth with type 1 diabetes who engage in more physical activity may have better health outcomes and health-related quality of life.
“Youth with type 1 diabetes who engage in more physical activity may have better health outcomes and health-related quality of life (256,257).”
From 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes:<i>Standards of Care in Diabetes—2023</i> (2023) · cites this paper as [256]
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- Authors
- Anderson, B. J., Laffel, L. M., Domenger, C., Danne, T., Phillip, M., Mazza, C., Hanas, R., Waldron, S., Beck, R. W., Calvi-Gries, F., & Mathieu, C.
- Affiliations
- Baylor College of Medicine (US)
- Joslin Diabetes Center (US)
- Sanofi (France) (FR)
- Kinderkrankenhaus auf der Bult (DE)
- Schneider Children's Medical Center (IL)
- Garrahan Hospital (AR)
- Sahlgrenska Academy, Gothenburg, Sweden
- National Children & Young People’s Diabetes Network, London, U.K.
- Jaeb Center for Health Research (US)
- Atlanstat, Rezé, France
- Universitair Ziekenhuis Leuven (BE)
- Corresponding author
- Anderson, Barbara J.
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2017-05-25
- Volume
- 40
- Issue
- 8
- Pages
- 1002-1009
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- PMC
- PMC5864137
- OpenAlex
- W2619527418
- Cited by
- 170
- References
- 30
- Citations by year
- 2026: 8 · 2025: 12 · 2024: 11 · 2023: 26 · 2022: 22 · 2021: 24 · 2020: 31 · 2019: 18 · 2018: 15 · 2017: 3
- FWCI
- 14.47
- Type
- journal article
- Language
- en
- Update notices
- correction (2018-03-01)
- Open access
- green
- europepmc.org
- Locations
- Diabetes Care (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Lirias (submittedVersion)
- Funders
- Sanofi
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Keywords
- type 1 diabetes, youth, young adults, glycemic control, HbA1c, diabetes self-management behavior, blood glucose monitoring, physical activity, food intake measurement, sex differences
- MeSH terms
- Self-Management, Adolescent, Adult, Blood Glucose, Child, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Female, Glycated Hemoglobin, Humans, Insulin, Male, Quality of Life, Health Behavior, Exercise, Body Mass Index, Multivariate Analysis, Linear Models, Young Adult
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