The DOI matches its Crossref record; 16 of the 18 references it cites were found in a registry or an index.
Glucose Management Indicator (GMI): A New Term for Estimating A1C From Continuous Glucose Monitoring
Open accessAbstract
While A1C is well established as an important risk marker for diabetes complications, with the increasing use of continuous glucose monitoring (CGM) to help facilitate safe and effective diabetes management, it is important to understand how CGM metrics, such as mean glucose, and A1C correlate. Estimated A1C (eA1C) is a measure converting the mean glucose from CGM or self-monitored blood glucose readings, using a formula derived from glucose readings from a population of individuals, into an estimate of a simultaneously measured laboratory A1C. Many patients and clinicians find the eA1C to be a helpful educational tool, but others are often confused or even frustrated if the eA1C and laboratory-measured A1C do not agree. In the U.S., the Food and Drug Administration determined that the nomenclature of eA1C needed to change. This led the authors to work toward a multipart solution to facilitate the retention of such a metric, which includes renaming the eA1C the glucose management indicator (GMI) and generating a new formula for converting CGM-derived mean glucose to GMI based on recent clinical trials using the most accurate CGM systems available. The final aspect of ensuring a smooth transition from the old eA1C to the new GMI is providing new CGM analyses and explanations to further understand how to interpret GMI and use it most effectively in clinical practice. This Perspective will address why a new name for eA1C was needed, why GMI was selected as the new name, how GMI is calculated, and how to understand and explain GMI if one chooses to use GMI as a tool in diabetes education or management.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The mean glucose of 154±26.8 mg/dL corresponded with an HbA1c of approximately 7%.14”
From Clinical utility of the twiist Automated Insulin Delivery System: first study with twiist (2026) · cites this paper as [14]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Using the standardized report the clinician can also address glucose variability (e.g., %CV metric) (75) or use glucose management indicator (GMI) metric (43) to discuss the possible discrepancies noted in glucose exposure derived from CGM data versus the individual's laboratory-measured A1C (40; 76).”
From Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range (2019) · cites this paper as [75]
The cited source says what the claim attributes to it.
In the citing paper
“For example, if HbA1c is lower than a concurrent GMI measure, the HbA1c can be interpreted to underestimate average blood glucose by the difference in measurements, allowing adjustment of HbA1c targets accordingly. 230,231”
From KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease (2022) · cites this paper as [230]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
International consensus on use of continuous glucose monitoring
Danne, T., Nimri, R., Battelino, T., Bergenstal, R. M., Close, K. L., DeVries, J. H., Garg, S., Heinemann, L., Hirsch, I., Amiel, S. A., et al. (2017) · Diabetes Care · doi:10.2337/dc17-1600 · Cited by 2,069 · cited 1×
“An international consensus group recently included the eA1C in its list of core CGMmetrics recommended for inclusion in all standard CGM reports (2).”
BackgroundSelf-citationTranslating the A1C assay into estimated average glucose values
Nathan, D. M., Kuenen, J., Borg, R., Zheng, H., Schoenfeld, D., Heine, R. J., & for the A1c-Derived Average Glucose (ADAG) Study Group (2008) · Diabetes Care · doi:10.2337/dc08-0545 · Cited by 1,812
Miller, K. M., Foster, N. C., Beck, R. W., Bergenstal, R. M., DuBose, S. N., DiMeglio, L. A., Maahs, D. M., & Tamborlane, W. V. (2015) · Diabetes Care · doi:10.2337/dc15-0078 · Cited by 1,254
Self-citationBeck, R. W., Riddlesworth, T., Ruedy, K., Ahmann, A., Bergenstal, R., Haller, S., Kollman, C., Kruger, D., McGill, J. B., Polonsky, W., et al. (2017) · JAMA · doi:10.1001/jama.2016.19975 · Cited by 1,185
Self-citationBeck, R. W., Riddlesworth, T. D., Ruedy, K., Ahmann, A., Haller, S., Kruger, D., McGill, J. B., Polonsky, W., Price, D., Aronoff, S., et al. (2017) · Annals of Internal Medicine · doi:10.7326/m16-2855 · Cited by 635
Self-citation4. Lifestyle Management: Standards of Medical Care in Diabetes—2018
American Diabetes Association (2018) · Diabetes Care · doi:10.2337/dc18-s004 · Cited by 563
Heinemann, L., Freckmann, G., Ehrmann, D., Faber-Heinemann, G., Guerra, S., Waldenmaier, D., & Hermanns, N. (2018) · The Lancet · doi:10.1016/s0140-6736(18)30297-6 · Cited by 522 · cited 1×
“To validate this formula, CGM data from the HypoDE study (10) (141 individuals with T1D for whom 4 weeks of data were collected with the Dexcom G5 sensor prior to A1C measurement) were analyzed to compute the regression equation to estimate A1C from the CGMmeasured mean glucose concentration.”
MethodSelf-citationThe fallacy of average: how using HbA1c alone to assess glycemic control can be misleading
Beck, R. W., Connor, C. G., Mullen, D. M., Wesley, D. M., & Bergenstal, R. M. (2017) · Diabetes Care · doi:10.2337/dc17-0636 · Cited by 477
Self-citationAleppo, G., Ruedy, K. J., Riddlesworth, T. D., Kruger, D. F., Peters, A. L., Hirsch, I., Bergenstal, R. M., Toschi, E., Ahmann, A. J., Shah, V. N., et al. (2017) · Diabetes Care · doi:10.2337/dc16-2482 · Cited by 329
Self-citationBergenstal, R. M., Ahmann, A. J., Bailey, T., Beck, R. W., Bissen, J., Buckingham, B., Deeb, L., Dolin, R. H., Garg, S. K., Goland, R., et al. (2013) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2013.0051 · Cited by 307
Self-citation
Flagged first, then by citations
2 of the 18 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 401–500 of 615
Stimson, R. H., Crane, M. S., Dover, A., Forbes, S., Wright, R. J., Lyall, M. J., Strachan, M. W. J., & Gibb, F. (2025) · Diabetes, obesity and metabolism · doi:10.1111/dom.70365 · Cited by 3
“9 The value of GMI as an accurate reflection of HbA1c has been questioned.”
Ganga, C. S.-L., Arranz-Martin, J. A., Jiménez-Díaz, J., Hernando-Alday, I., Navas-Moreno, V., García, M. D. M. F., Gómez, G. L. R., Hierro, J. G., Lobariñas, L. E. L., de Icaya, P. M., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-19705-0 · Cited by 3
“The calculation follows the validated formula proposed by Bergenstal et al. 12 : GMI (”
Ehlert, B., Aron, D., Perelman, D., Wu, Y., & Snyder, M. P. (2025) · Diabetes Technology & Therapeutics · doi:10.1177/15209156251374711 · Cited by 4
Armentrout, B. L., Wenzell, M. L., Strohl, K. P., Crawford, S. L., Wood, J., Li, C.-S. R., Hickman, R. L., & Griggs, S. A. (2025) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2025.103305 · Cited by 4
Glucose management indicator: Do we need device-specific equations?
Jávorfi, T., Kocsis, G., Svébis, M. M., Ferencz, V., Domján, B. A., Kézdi, Á., Hankó, H., Putz, Z., & Tabák, Á. G. (2025) · Diabetes & Metabolism · doi:10.1016/j.diabet.2025.101661 · Cited by 3
Piloya, T., Nyangabayaki, C., Dunn, T. C., MALINGA, D., JEMIMA, N., Pappenfus, E., Zhang, L., Bindal, A., Beasley, S., Sunni, M., et al. (2025) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2024.0537 · Cited by 1
“4,18,24 9, 25 In contrast, The young age of our participants (4 – 16 years) might be relevant to our fi ndings, since MG levels for a given A1c are known to be higher in youth compared with adults.”
Evaluation of continuous glucose monitoring and nutritional status in glycogen storage diseases
Akın, B. K., & Göksoy, E. (2025) · Journal of Pediatric Endocrinology & Metabolism (JPEM) · doi:10.1515/jpem-2024-0597 · Cited by 3
Assessing the Accuracy of CGM Metrics: The Role of Missing Data and Imputation StrategiesPreprint
Cichosz, S. L., Kronborg, T., Hangaard, S., Vestergaard, P., & Jensen, M. H. (2025) · medRxiv · doi:10.1101/2025.02.13.25322196 · Cited by 3
“• Glucose Management Indicator (GMI) [28]: The GMI provides an estimate of average glucose levels by applying a formula that correlates with HbA1C values.”
Ajjan, R., Battelino, T., Seufert, J., Blin, P., de Pouvourville, G., Vicaut, É., Carcaillon‐Bentata, L., Levrat‐Guillen, F., Cosson, E., & Joubert, M. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-085961 · Cited by 5
Liu, Z., Lin, B., Chen, D., Yang, Y., Jiang, W., Yang, D., Yan, J., Yao, B., Yang, X., & Xu, W. (2024) · Endocrine · doi:10.1007/s12020-024-04083-w · Cited by 6
“GMI and laboratory-measured HbA1c showed great agreement in the derivation studies of the GMI equation [12].”
Heald, A. H., Stedman, M., Warner-Levy, J. J., Belston, L., Paisley, A. N., Jotić, A., Lalic, N. M., Gibson, M., Habte‐Asres, H. H., Whyte, M., et al. (2024) · Diabetes Therapy · doi:10.1007/s13300-024-01647-x · Cited by 3
Henry, Z., Villar, E., Chauvet, C., Belloi, A., Prunescu, I., Doroszewski, F., Luyton, C., & Marchand, L. (2024) · Acta Diabetologica · doi:10.1007/s00592-024-02323-z · Cited by 3
Pandey, A. K., Naik, B., Uday, R., & Shivaprasad, C. (2024) · Cureus · doi:10.7759/cureus.61849 · Cited by 3
“Laboratory A1C might be similar to, higher than, or lower than GMI [8,9].”
BackgroundSpitzer, A. I., Rodbard, H. W., Iqbal, S. U., Nakazawa, M., DiGiorgi, M., & Winston, R. (2024) · The Journal of Arthroplasty · doi:10.1016/j.arth.2024.05.055 · Cited by 1
Q-Score Complements the Time in Range in the Evaluation of Short-Term Glycemic Control
Augstein, P., Heinke, P., Nowak, A., Salzsieder, E., & Kerner, W. (2024) · Journal of Diabetes Science and Technology · doi:10.1177/19322968241246209 · Cited by 3
“26 The glycemia risk index (GRI) was determined in accordance with a recent publication.”
The Relationship Between Glycated Hemoglobin and Time in Range in a Pediatric Population
Vandenbempt, M., Matheussen, H., Charleer, S., Rochtus, A. M., & Casteels, K. (2023) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2023.0482 · Cited by 2
“25 Others, such as Vigersky et al., opted for HbA1c as a predictor in their studies.”
Susanti, Y., Salam, M. Y., & Guilin, X. (2023) · Journal International Inspire Education Technology · doi:10.55849/jiiet.v1i3.237 · Cited by 3
“For example, the higher a person's education level, the more sophisticated the technology he will face (Bergenstal et al., 2018).”
BackgroundDynamic circadian fluctuations of glycemia in patients with type 2 diabetes mellitus
Vásquez-Muñoz, M., Arce-Álvarez, A., Álvarez, C., Ramirez-Campillo, R., Crespo, F., Arias, D., Salazar-Ardiles, C., Izquierdo, M., & Andrade, D. (2022) · Biological Research · doi:10.1186/s40659-022-00406-1 · Cited by 3
Rimac, D. S., Bilić-Čurčić, I., Prpić-Kriẑevac, I., Schönberger, E., Centner, M. G., Barišić, M., & Canecki-Varžić, S. (2022) · Healthcare · doi:10.3390/healthcare10091792 · Cited by 5
Profil ambulatoire du glucose : proposition d’un guide d’utilisation pratique
Tatulashvili, S., Sal, M., & Cosson, E. (2022) · Médecine des Maladies Métaboliques · doi:10.1016/j.mmm.2022.05.007 · Cited by 2
Levrat‐Guillen, F., & Ghazi, T. (2022) · Diabetes Therapy · doi:10.1007/s13300-022-01251-x · Cited by 4
Improved Time in Range During 28 Days of Meal Delivery for People With Type 2 Diabetes
Clark, C. N., Hart, B. B., McNeil, C. K., Duerr, J. M., & Weller, G. B. (2022) · Diabetes Spectrum · doi:10.2337/ds21-0093 · Cited by 2
“mg/dL Glycemic variability (GV), the coefficient of variation of observed CGM readings Percentage of participants achieving and maintaining a TIR $70% or a GMI #7% (22).”
BackgroundPujante, P., Felgueroso, C. A., Ares, J., Morales-Sánchez, P., Lambert, C., Escobedo, R. R., Rodríguez‐Rodero, S., Delgado, E., & Torre, E. L. M. (2022) · Endocrinología Diabetes y Nutrición · doi:10.1016/j.endinu.2021.10.008 · Cited by 2
Staszak, W., Chromik, J., Braune, K., & Bert Arnrich, A. (2021) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc46164.2021.9629487 · Cited by 4
Yeoh, E. C. K., Png, D., Koh, P. L., Sum, C. F., Lim, S. C., Tan, H. H., Ubeynarayana, C. U., & Subramaniam, T. (2021) · Diabetic Medicine · doi:10.1111/dme.14733 · Cited by 5
Individualisierung der Diabetestherapie durch Automatisierung der Insulingabe
Biester, T., Dovč, K., Chobot, A. P., Tauschmann, M., & Kapellen, T. M. (2021) · Monatsschrift Kinderheilkunde · doi:10.1007/s00112-021-01239-0 · Cited by 4
Deeb, A., Muammar, T., Alsaffar, H., Sedaghat, S., Hassani, N. A., Odeh, R., Alkhayyat, H., Sinani, A. A., Attia, N. A., Adhami, S., et al. (2021) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2021.108671 · Cited by 7
The pharmacist’s role in continuous glucose monitoring
Isaacs, D. M. (2020) · Pharmacy Today · doi:10.1016/j.ptdy.2020.04.014 · Cited by 5
Ranting in 2019: Are Things Improving?
Hirsch, I. (2019) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2019.0004 · Cited by 3
Accuracy of a continuous glucose monitoring system in people with diabetes on peritoneal dialysis
Williams, J. K., Gilchrist, M., & Shore, A. C. (2025) · Peritoneal Dialysis International · doi:10.1177/08968608251406514 · Cited by 1
“16 The relationship between GMI and HbA1c and Hba1c and average glucose was described using Spearman ’ s correlation coef fi cient.”
Arce, N. N., Vu, M. H., Barnett, B., & Black, D. S. (2025) · Journal of Diabetes Science and Technology · doi:10.1177/19322968251398876 · Cited by 2
“GMI was derived from mean glucose using the equation proposed by Bergenstal et al. 15 As recommended, GMI was used here as a CGM-derived summary metric rather than a diagnostic substitute for measured HbA1c.”
Mizutani, K., Uenishi, E., Onoue, T., Maeda, R., Suzuki, K. A. O., Handa, T., Kobayashi, T., Iwama, S., Miyata, T., Sugiyama, M., et al. (2025) · Journal of Diabetes Investigation · doi:10.1111/jdi.70191 · Cited by 2
“12 GMI is considered a more direct re fl ection of mean glucose levels and provides an alternative measure of glycemic control that is not affected by erythrocyte lifespan or hemoglobin glycation variability.”
Chong, G. Y., Kaur, S., Talib, R. A., Loy, S., Tan, H., Abdullah, R. B., Mahmud, H. B., Siah, W. Y., Kee, C., & Koo, H.-C. (2025) · Journal of Sleep Research · doi:10.1111/jsr.70218 · Cited by 2
Yang, D., Ling, P., Wang, C., Zheng, X., Deng, H., Yang, X., Yan, J., Xu, W., Luo, S., & Weng, J. (2025) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.70048 · Cited by 2
“HbA1c serves as a crucial metric for assessing the glucose levels andpregnancyoutcomesinpregnancy[7,10].”
InfluentialCalliari, L. E., Sepúlveda, Á. C., Coronel-Restrepo, N., Kabakian, L., Lamounier, R. N., Picasso, E., PROIETTI, A. E., Rincón, A. R., & Yepez-Rodríguez, A. E. (2025) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-025-01702-y · Cited by 2
“Similarly, the GMI serves as a reference for HbA1c values and supports the overall interpretation of the glycemic profile, facilitating the transition from traditional assessment methods to new CGM-based metrics [14].”
Williamson, W., Lee, J. M., & Gaynanova, I. (2025) · Journal of Diabetes Science and Technology · doi:10.1177/19322968251319801 · Cited by 3
Shah, V. N., DEX, T. A., Meneghini, L., Rodrigues, A., & Polonsky, W. H. (2025) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16251 · Cited by 2
Tallon, E. M., Williams, D. D., Schweisberger, C., Mullaney, C., Lockee, B., Ferro, D., Vandervelden, C. A., Barnes, M. S., Sarteau, A. C., Kahkoska, A. R., et al. (2025) · JMIR Diabetes · doi:10.2196/69142 · Cited by 3
“Recent efforts have also explored the use of ML classifiers that use 2 weeks of CGM data to forecast 90-day HbA 1c in youth with T1D [53].”
Diagnostik, Therapie und Verlaufskontrolle des Typ-1-Diabetes mellitus im Kindes- und Jugendalter
Holder, M., Ziegler, R., Kamrath, C., Lange, K., & Kummer, S. (2024) · Diabetologie und Stoffwechsel · doi:10.1055/a-2374-0813 · Cited by 2
“Der GMI liefert eine Schätzung des A1C-Wertes auf der Grundlage eines Durchschnitts der CGM-Glukosewerte, die eine Person über einen Zeitraum von mehreren Wochen hatte [71].”
Shi, J., Weng, J., Ding, Y., Xia, Y. Y., Zhou, Y., Wang, X., Zhang, F., Zhang, P., Luo, S., Zheng, X., et al. (2024) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.70001 · Cited by 2
“…deviation (SD), coefficient of variation (CV) and largest amplitude of glycaemic excursions (LAGE); (5) glucose management indicators (GMI) [56]; (6) hypoglycaemia and hyperglycaemia event: beginning of a CGM event was defined as the sensor readings below or above the threshold for at…”
Bhat, S., Al-Hajri, N., Kanbour, S., Ahmadzada, M., Borovoy, A., Abusamaan, M. S., Canner, J., Nass, C., Sherman, R. L., Hines, K. F., et al. (2024) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2024.08.007 · Cited by 2
“CGM may be more sensitive to short-term changes in glycemia, as reflected by time in range or glucose management indicator [26].”
Newer Outpatient Diabetes Therapies and Technologies
Kamal, N., Lee, K., & Aleppo, G. (2024) · Medical Clinics of North America · doi:10.1016/j.mcna.2024.03.002 · Cited by 2
Self-citationSartini, J., Fang, M., Rooney, M. R., Selvin, E., Coresh, J., & Zeger, S. L. (2024) · Journal of Diabetes Science and Technology · doi:10.1177/19322968241245654 · Cited by 1
Exploring time in tight range targets (TITR) in drug-naive Japanese individuals with type 2 diabetes
Ishiguro, M., Ando, K., & Nishimura, R. (2024) · Acta Diabetologica · doi:10.1007/s00592-024-02247-8 · Cited by 2
Buckingham, B. A., & Bergenstal, R. M. (2024) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2023.0505 · Cited by 4
Self-citationVISENTIN, R., Cobelli, C., Sieber, J., & Man, C. D. (2024) · Journal of Diabetes Science and Technology · doi:10.1177/19322968231223936 · Cited by 2
Lopes, V., Peixoto, A. C., & Lages, A. D. S. (2024) · Acta Diabetologica · doi:10.1007/s00592-023-02223-8 · Cited by 2
Canecki-Varžić, S., Prpić-Kriẑevac, I., Berković, M. C., Rahelić, D., Schönberger, E., Gradišer, M., & Bilić-Čurčić, I. (2023) · Medicina · doi:10.3390/medicina59111893 · Cited by 2
“A formula based on the ADAG study was used for calculating GMI [14].”
MethodTakahara, M., Shiraiwa, T., Katakami, N., Maeno, Y., Yamamoto, K., Shiraiwa, Y., Yoshida, Y., Kozawa, J., & Shimomura, I. (2023) · Internal Medicine · doi:10.2169/internalmedicine.1441-22 · Cited by 2
Can HbA1c Alone Be Safely Used to Guide Insulin Therapy in African Youth with Type 1 Diabetes?
Piloya, T., Mungai, L., Moran, A., Yauch, L. M., Christakis, N. J., Zhang, L., McCarter, R., & Chalew, S. A. (2023) · Pediatric Diabetes · doi:10.1155/2023/1179830 · Cited by 3
“However, HbA1c = 8% (63.9 mmol/mol) corresponded to 183 mg/dL (10.1 mmol/L) with the ADAG reference, MBG = 196 mg/dL (10.8 mmol/L) in the GMI population, and 206 mg/dL (11.4 mmol/L) from NOLA.”
InfluentialWild, D., Kerr, M., Figueiredo, C., & Partridge, H. (2023) · Practical Diabetes · doi:10.1002/pdi.2445 · Cited by 2
Hayek, A. A., Alzahrani, W. M., Sobki, S. H., Alsaeed, A. H., & Dawish, M. A. A. (2023) · Cureus · doi:10.7759/cureus.33416 · Cited by 1
“Debate exists about the independent impact of glycemic variability on DM-related complications that go beyond average glucose or HbA1c [18-21].”
BackgroundLamine, F., Pruijm, M. T., Bahon, V., & Zanchi, A. (2022) · Kidney and Dialysis · doi:10.3390/kidneydial2030042 · Cited by 2
Valenzano, M., Bertolotti, I. C., Grassi, G., Broglio, F., & Valenzano, A. (2022) · Journal of Diabetes Science and Technology · doi:10.1177/19322968221081556 · Cited by 2
Time in range is a tool for assessing the quality of glycemic control in diabetes
Суплотова, Л. А., Сергеевна, С. А., Романова, Н. В., & Shestakova, M. V. (2021) · Diabetes Mellitus · doi:10.14341/dm12703 · Cited by 9
Flash Continuous Glucose Monitoring: A Practical Guide and Call to Action for Pharmacists
Cowart, K., & Zgibor, J. C. (2021) · Journal of Pharmacy Practice · doi:10.1177/08971900211000273 · Cited by 4
“The AGP provides the average glucose over the sensor wear period along with a metric called the glucose management indicator (GMI), which is used to estimate HbA1c from the average glucose.(56) The GMI can be used to explore reasons for the discordant results, if applicable.”
MethodLitwak, L., Carreño, N., Carnero, R., Daín, A., Grosembacher, L., Musso, C., Proietti, A., Rista, L., Rovira, G., Rubín, G., et al. (2020) · Revista de la Sociedad Argentina de Diabetes · doi:10.47196/diab.v54i3.455 · Cited by 2
Picard, S. (2020) · Médecine des Maladies Métaboliques · doi:10.1016/j.mmm.2020.06.021 · Cited by 1
“été changé et qu'on parle maintenant d'index de gestion de la glycémie, ou GMI (pour Glucose Management Indicator) [9].”
BackgroundInfluentialGlycaemic Monitoring in Diabetic Kidney Disease – Is HbA1c Reliable?
Isa, S. B., Hami, R. B., JA, A. N. J. N., Noordin, S. S., & Ismail, T. S. T. (2021) · Journal of Health Science and Medical Research · doi:10.31584/jhsmr.2021831 · Cited by 1
“02392 × [mean glucose in milligram per decilitre].(53) Another CGM metric of clinically importance, is time in range.”
BackgroundTillman, J. B., Beck, R. W., Polonsky, W. H., Calhoun, P., Mouse, T., Bailey, R., Jacoby, J., Nandan, R., Sheikh, F. N., & Malone, J. K. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgae778 · Cited by 1
Self-citationWu, T., Guan, Z., & Cai, W. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1898713 · Cited by 1
“When the disagreement is large enough to in fl uence care, a lower-risk interpretation examines both sides of the comparison before therapy is changed (6, 11).”
Olamoyegun, M., Olamoyegun, O. D., Akinlade, A. T., Saliu, O. O., & Adeyemi, T. A. (2026) · Cardiovascular Diabetology – Endocrinology Reports · doi:10.1186/s40842-026-00310-7
“These metrics facilitate individualized diabetes management by identifying specific glucose patterns requiring intervention, such as nocturnal hypoglycaemia, post-prandial hyperglycaemia, or excessive glycaemic variability [20].”
Dagan, A., Yackobovitch‐Gavan, M., Phillip, M., & Nimri, R. (2026) · Diabetes Technology & Therapeutics · doi:10.1177/15209156261459274 · Cited by 1
“15 Although designed to complement or replace laboratory HbA1c, accumulating evidence demonstrates frequent and sometimes substantial discrepancies between the two.”
Jiang, Y., Gu, L., MA, Y., Qu, Y., Wan, H., Lv, K., Zhu, Q., Zhou, H., Sun, J., Lu, F., et al. (2026) · Diabetes Obesity and Metabolism · doi:10.1111/dom.70973 · Cited by 1
“In nondiabetic populations, previous studies have also shown that there can be significant inconsistencies between GMI and laboratory HbA1c [43, 44].”
Camuto, P., Guadagnini, D., Assalin, H. B., Magro, D. O., Santos, A., & Saad, M. J. A. (2026) · AACE Endocrinology and Diabetes · doi:10.1016/j.aed.2026.06.010 · Cited by 1
Katzmarzyk, P. T., DREWS, K., Ard, J. D., McLaughlin, T., Harris, M. N., Lee, A., Foster, G. D., Lee, H. J., Dunn, T. C., Martin, C. K., et al. (2026) · Obesity · doi:10.1002/oby.70204 · Cited by 1
Ahmed, A., Batth, J., Wang, Q., Vigers, T., Ode, K. L., Chan, C. L., & Moheet, A. A. (2026) · Endocrine Practice · doi:10.1016/j.eprac.2026.04.007 · Cited by 1
Rodbard, D., Augstein, P., Heinke, P., Salzsieder, E., Thomas, A., & Reindel, J. (2026) · Diabetes Technology & Therapeutics · doi:10.1177/15209156261423504 · Cited by 1
“…%time in range 70 – 180 mg/dL (3.9 – 10 mmol/L); GMI, Glycemic Management Indicator calculated from mean sensor glucose using a linear relationship 9 ; GRI, Glycemia Risk Index 21 ; MODD, Mean of absolute Daily Differences (mg/dL or mmol/L) 17 ; MSG, mean sensor glucose; Range: average daily…”
InfluentialClinical Value of HbA1c/updatedGMI Ratio in Identifying Early Retinopathy Risk in Type 1 Diabetes.
Lurquin, F., Petit, E., Oriot, P., Ahn, S., & Hermans, M. (2026) · Journal of Diabetes Science and Technology · doi:10.1177/19322968261426305 · Cited by 1
Wu, Y., Feng, K., Fu, Y., Zhuo, Q., Zheng, M., Zhang, H., Lin, G., Liang, X.-Y., Zhou, X.-H., Ji, L., et al. (2026) · Diabetes, obesity and metabolism · doi:10.1111/dom.70558 · Cited by 1
“16 Common time-domain metrics including time in range (TIR), time below range (TBR), time above range (TAR), coefficient of variation (CV), standard deviation (SD), and Mean amplitude of glucose excursions (MAGE) describe overall glucose control and fluctuation magnitude.”
Navigating the dual burden of type 1 diabetes and mental illness: A phenomenological study
Cooper, Z., Davis, G. M., Pasquel, F., & Johnson, L. (2026) · Diabetic Medicine · doi:10.1111/dme.70200 · Cited by 1
Williams, E., Rand, C., Ayers, A. T., Ho, C., DuBord, A. Y., Klonoff, D. C., & Espinoza, J. (2026) · JMIR Diabetes · doi:10.2196/92455 · Cited by 4
“AUC e [22,42,43] Indicator of glycemic excursions in a specified period Reflects duration of CGM usage for data reliability. eA1c [31] Tracking of average glycemia and the estimation of HbA 1c eA1c(t)=0.9512 * eA1c (t-1 d) +0.0488 * f (SMBG) Fills the gap between infrequent laboratory HbA 1c tests.”
InfluentialArslan, E., Balkı, H. G., Kızılay, D., Demir, G., Özen, S., Darcan, S., & Gökşen, D. (2026) · Journal of Clinical Research in Pediatric Endocrinology · doi:10.4274/jcrpe.galenos.2025.2025-10-11 · Cited by 1
“HbA1c cannot capture short-term glucose fluctuations or provide information about glycemic variability, hypoglycemic episodes, or postprandial excursions (3).”
Insulin Pump Guide for Health Care Professionals: Settings, Interpretation, and Adjustment
Lansang, M. C., Malloy, K., Knapp, S., Veeramachaneni, R., Rahhal, M.-N., Arce, K. M., Mucci, A., Zhou, K., & Isaacs, D. M. (2026) · Endocrine Practice · doi:10.1016/j.eprac.2025.12.025 · Cited by 1
DeSalvo, D. J., Linde, N. M., Sickler, J. K., Villegas, C., & Cescon, M. (2026) · Journal of Diabetes Research · doi:10.1155/jdr/2896084 · Cited by 1
“GMI was used in this study as a calculated estimate of laboratory-measured HbA1C [6] since HbA1c was not routinely available at the key study time points.”
Automated Insulin Delivery Beyond Glycemic Outcomes: Endpoints and Evidence
Jones, H. C., Trawley, S. L., Jenkins, A. J., MacIsaac, R. J., Kong, Y. W., Morrison, D., & O'Neal, D. N. (2025) · Diabetes Technology & Therapeutics · doi:10.1177/15209156251390831 · Cited by 1
“32 36 While there have been limited studies on associations between CGM use and progression to diabetic nephropathy, increased TIR has been show to signi fi cantly reduce albuminuria.”
Jeandidier, N., Bagel, A., Bonin, A., Guigand, G., & Guerci, B. (2025) · Diabetes Therapy · doi:10.1007/s13300-025-01814-8 · Cited by 1
Salman, I., Gharab, K., Ghannawi, L., & Abed, B. A. (2025) · Dijlah Journal of Medical Sciences P-ISSN:3078-3178, E-ISSN:3078-8625 · doi:10.65204/djms-c-l-hsm · Cited by 1
“Therefore, using HbA1c alone without taking into account data from continuous glucose monitoring (CGM) may understate the risk of complications from diabetes, especially in individuals with type1 diabetes or type2 diabetes receiving insulin [10].”
Gera, S., Rearson, A., Gallop, R., & Marks, B. E. (2025) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2025.0173 · Cited by 1
Niwaha, A. J., Balungi, P., McDonald, T. J., Hattersley, A. T., Shields, B. M., Nyirenda, M., & Jones, A. G. (2025) · Diabetic Medicine · doi:10.1111/dme.70011 · Cited by 5
“15,16 We compared the performance of HbA 1c , GA and fructosamine to identify participants with CGM glucose values ≥ 8 mmol/L using receiver operating characteristic (ROC) curve analysis, and assessed the sensitivity, specificity and positive/negative predictive values of these tests using the…”
Topalian, N., Picard, S., Riveline, J., Canha, D., Julla, J., Lablanche, S., Salle, L., Sonnet, E., Berot, A., Gouet, D., et al. (2025) · Diabetes & Metabolism · doi:10.1016/j.diabet.2025.101647 · Cited by 1
Chen, Y.-E., Ku, C. W., Chong, M. F., Yap, F. K. P., Chan, J. K. Y., Loy, S. L., & Chen, L. (2025) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2025.04.026 · Cited by 5
Lazăr, S., Potre, O., Ioniță, I., Reurean‐Pintilei, D., Timar, R. Z., Herascu, A., Avram, V. F., & Timar, B. (2025) · Biosensors · doi:10.3390/bios15030190 · Cited by 2
“It is essential to set individualized, realistic and safe goals in such instances/cases, since an excessive focus on constantly achieving the ideal GMI value may increase pressure for the patient, potentially exacerbating the emotional stress [17,46].”
Aljohani, R. A., Altaib, H. N., & Kofi, M. A. (2025) · Cureus · doi:10.7759/cureus.79705
“However, the development of continuous glucose monitoring (CGM) systems has revolutionized diabetes care [4].”
Zoet, S., Urgert, T., Veldhuis, A., van Beijnum, B.-J. F., & Laverman, G. D. (2025) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2024-004768 · Cited by 1
Алимова, И. Л., & Demyanenko, A. N. (2024) · Russian Medicine · doi:10.17816/medjrf629450 · Cited by 1
Secco, K., Baumann, P., Pöttler, T., Aberer, F., Cigler, M., Elsayed, H., Harer, C., Weitgasser, R., Schütz-Fuhrmann, I., & Mader, J. (2024) · Italian National Conference on Sensors · doi:10.3390/s24144514 · Cited by 1
“…variation ( CV gluc ) for an individual i in phase p is the standard deviation ( SD gluc ) of glucose measurements ( G 1 ... j ) divided by Mean gluc : where The glucose management indicator ( GMI ) for an individual i in phase p is calculated by the formula given by Bergenstal et al. [27].”
MethodTime in range prediction using the experimental mobile application in type 1 diabetes
Русанов, А. Н., & Родионова, Т. И. (2024) · Diabetes Mellitus · doi:10.14341/dm13111 · Cited by 2
The Glucose Management Indicator: Time to Change Course? Diabetes Care 2024;47:906–914
Bergenstal, R. M., & Beck, R. W. (2024) · Diabetes Care · doi:10.2337/dc24-0317 · Cited by 3
Self-citationShahid, A., & Lewis, D. M. (2024) · Diabetology · doi:10.3390/diabetology5050038 · Cited by 1
Alsewy, F. Z., Megallaa, M., Imbaby, S., Zidan, H. M., Kassab, H., & Badrah, M. (2024) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2024.0066 · Cited by 1
Intermittently Scanned Continuous Glucose Monitoring Performance in Patients With Liver Cirrhosis
Rigon, F., Ronsoni, M. F., Hohl, A., Vianna, A. G. D., van de Sande‐Lee, S., & Schiavon, L. D. L. (2024) · Journal of Diabetes Science and Technology · doi:10.1177/19322968241232686 · Cited by 3
Manov, A. E., Holt, N., Dini, E., Rivera, R., Donepudi, A., Haddadin, R. W., Mefferd, K., & Qadir, I. (2024) · Cureus · doi:10.7759/cureus.56768 · Cited by 1
“This study looked at 528 individuals without other comorbidities from four clinical trials [2].”
BackgroundMethodInfluentialLeite, R. O., Brodar, K. E., Saab, P. G., Marchetti, D., Jaramillo, M., Sanchez, J. E., Davis, E., Delamater, A. M., & Greca, A. M. L. (2024) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-023-09995-9 · Cited by 1
“Paired samples t -tests assessed for differences in HbA1c and psychosocial functioning between the two timepoints, from before the pandemic began to the year after the pandemic started.”
InfluentialGarretson, S., Parmar, A. M., Streisand, R. M., Jaser, S. S., & Datye, K. A. (2024) · The Science of Diabetes Self-Management and Care · doi:10.1177/26350106231220023 · Cited by 2
Primary care diabetes assessment when HbA1c and other measures of glycemia disagree
Friedman, J. G., Smith, E. P., Awasty, S. S., Behan, M., Genco, M. T., Hempel, H. C., Jafri, S., Jandarov, R., Nagaraj, T., Franco, R. S., et al. (2024) · Primary care diabetes · doi:10.1016/j.pcd.2023.12.005 · Cited by 1
Evaluation of HbA1c from CGM traces in an Indian population
Majumdar, S., Kalamkar, S. D., Dudhgaonkar, S., Shelgikar, K. M., Ghaskadbi, S., & Goel, P. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1264072 · Cited by 2
“Bergenstal et al. (15) renamed the estimated HbA1c as the glucose management indicator (GMI), a metric for glycemic control and management.”
BackgroundRoversi, C., Camerlingo, N., Vettoretti, M., Facchinetti, A., Choudhary, P., Sparacino, G., & Favero, S. D. (2023) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2023.107943 · Cited by 1
Henao, D. C., Medina, A. M. G., García-Cajiao, A., Robledo, S., Mejía, G., Padilla, S. N. C., Kerguelen, A., Rubio, C., Rondón, M., & Múñoz, Ó. (2023) · Revista Colombiana de Endocrinología Diabetes & Metabolismo · doi:10.53853/encr.10.3.796
“La mediana de TIR 75 % [RIC 63-92], TBR 3 % [1-7], TAR 15 % [3-27].”
BackgroundInfluentialHiemstra, M. S., Reichert, S. M., & Mitchell, M. (2023) · JMIR Formative Research · doi:10.2196/46418 · Cited by 2
“To examine the potential impact of the program on behavioral and clinical risk factors, device-assessed (4) weekly mean daily step count and (5) estimated glycated hemoglobin (HbA 1c ; the average glucose level from the FreeStyle Libre readings for 14 or more days [17]) were collected.”
Background
Metadata
- Authors
- Bergenstal, R. M., Beck, R. W., Close, K. L., Grunberger, G., Sacks, D. B., Kowalski, A., Brown, A. S., Heinemann, L., Aleppo, G., Ryan, D. B., Riddlesworth, T. D., & Cefalu, W. T.
- Affiliations
- Park Nicollet Health Services (US)
- Jaeb Center for Health Research (US)
- The diaTribe Foundation, San Francisco, CA
- Grunberger Diabetes Institute (US)
- National Institutes of Health (US)
- Breakthrough T1D (US)
- Close Concerns (United States) (US)
- Science Consulting in Diabetes, Neuss, Germany
- Northwestern University (US)
- Sacred Heart Hospital (US)
- American Diabetes Association (US)
- Corresponding author
- Bergenstal, Richard M.
- ORCID
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2018-09-17
- Volume
- 41
- Issue
- 11
- Pages
- 2275-2280
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- PMC
- PMC6196826
- OpenAlex
- W2891178783
- Cited by
- 684
- References
- 18
- Citations by year
- 2026: 79 · 2025: 95 · 2024: 114 · 2023: 84 · 2022: 95 · 2021: 101 · 2020: 75 · 2019: 34 · 2018: 6
- FWCI
- 43.18
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Diabetes Care (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Sanofi
- National Institute of Diabetes and Digestive and Kidney Diseases (UC4DK108611)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- glucose management indicator, continuous glucose monitoring, HbA1c, mean blood glucose, nomenclatural changes, diabetes management, diabetes education
- MeSH terms
- Blood Glucose, Diabetes Mellitus, Health Education, Health Status Indicators, Glycated Hemoglobin, Humans, Terminology as Topic, Statistics as Topic, Blood Glucose Self-Monitoring
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review