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Physiology of Insulin In Man: The Banting Memorial Lecture 1971
Abstract
Insulin serves as the body's signal for the fed or fasted state. High insulin levels, the “fed” signal, initiate tissue uptake and storage of fuels. Low insulin levels, the “fasted” signal, initiate mobilization of stored fuels from tissue stores, the rate being proportional to the lowness of the insulin. Certain metabolic states such as obesity or trauma alter the concentration of insulin at which no net transfer of fuel occurs, resulting in insulin resistance or hyper-sensitivity.
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Citations
Cited by
Insulin-Receptor Interaction in the Obese-Hyperglycemic Mouse
Kahn, C. R., Neville, D. M., & Roth, J. (1973) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)44468-2 · Cited by 408
Regulation of Body Weight in Humans
Jéquier, E., & Tappy, L. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.2.451 · Cited by 373
Garber, A. J., Cryer, P. E., Santiago, J. V., Haymond, M. W., Pagliara, A. S., & Kipnis, D. M. (1976) · Journal of Clinical Investigation · doi:10.1172/jci108460 · Cited by 351
Nasal absorption of insulin: enhancement by hydrophobic bile salts.
Gordon, G. S., Moses, A. C., Silver, R. D., Flier, J. S., & Carey, M. C. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.21.7419 · Cited by 278
Calbet, J. A. L., & MacLean, D. A. (2002) · The Journal of Nutrition · doi:10.1093/jn/132.8.2174 · Cited by 253
Metadata
- Authors
- Cahill, G. F.
- Venue
- Diabetes
- Publisher
- American Diabetes Association
- Published
- 1971-12-01
- Volume
- 20
- Issue
- 12
- Pages
- 785-799
- ISSN
- 0012-1797 (ISSN-L)
- 1939-327X
- OpenAlex
- W2125365329
- Cited by
- 356
- References
- 0
- FWCI
- 43.70
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cahill, G. F. (1971). Physiology of Insulin In Man: The Banting Memorial Lecture 1971. Diabetes. https://doi.org/10.2337/diab.20.12.785
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
