Cited by 218Diabetes Management and ResearchPancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record.

Lilly lecture 1989. Toward physiological understanding of glucose tolerance. Minimal-model approach

Bergman, R. N.·1989·Diabetes

DOI 10.2337/diabetes.38.12.1512

Open this paper in CoChat — free account

Integrity signals

Registry

Crossref · 10.2337/diabetes.38.12.1512

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Sorted by citations

Quantitative Insulin Sensitivity Check Index: A Simple, Accurate Method for Assessing Insulin Sensitivity In Humans
Katz, A., Nambi, S. S., Mather, K., Baron, A. D., Follmann, D. A., Sullivan, G., & Quon, M. J. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.7.6661 · Cited by 3,931
Pathogenesis of type 2 diabetes mellitus
DeFronzo, R. A. (2004) · Medical Clinics of North America · doi:10.1016/j.mcna.2004.04.013 · Cited by 1,342
Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study
Martin, B. C., Warram, J. H., Krolewski, A. S., Soeldner, J. S., Kahn, C. R., Martin, B. C., & Bergman, R. N. (1992) · The Lancet · doi:10.1016/0140-6736(92)92814-v · Cited by 1,158
Self-citation
Contributions of β-Cell Dysfunction and Insulin Resistance to the Pathogenesis of Impaired Glucose Tolerance and Impaired Fasting Glucose
Abdul-Ghani, M. A., Tripathy, D., & DeFronzo, R. A. (2006) · Diabetes Care · doi:10.2337/dc05-2179 · Cited by 744
Surrogate markers of insulin resistance: A review
Singh, B. (2010) · World Journal of Diabetes · doi:10.4239/wjd.v1.i2.36 · Cited by 622
Diabetes: Models, Signals, and Control
Cobelli, C., Dalla Man, C., Sparacino, G., Magni, L., De Nicolao, G., & Kovatchev, B. P. (2009) · IEEE Reviews in Biomedical Engineering · doi:10.1109/rbme.2009.2036073 · Cited by 511
“Only later this remote compartment was experimentally proven in dog studies to be the interstitial fluid [27].”
A Sustained Increase in Plasma Free Fatty Acids Impairs Insulin Secretion in Nondiabetic Subjects Genetically Predisposed to Develop Type 2 Diabetes
Kashyap, S., Belfort, R., Gastaldelli, A., Pratipanawatr, T., Berria, R., Pratipanawatr, W., Bajaj, M., Mandarino, L., DeFronzo, R., & Cusi, K. (2003) · Diabetes · doi:10.2337/diabetes.52.10.2461 · Cited by 503
C-Peptide Is the Appropriate Outcome Measure for Type 1 Diabetes Clinical Trials to Preserve β-Cell Function
Palmer, J. P., Fleming, G. A., Greenbaum, C. J., Herold, K. C., Jansa, L. D., Kolb, H., Lachin, J. M., Polonsky, K. S., Pozzilli, P., Skyler, J. S., et al. (2004) · Diabetes · doi:10.2337/diabetes.53.1.250 · Cited by 491
The Insulin Resistance Atherosclerosis Study (IRAS)
Wagenknecht, L. E., Mayer, E. J., Rewers, M., Haffner, S. M., Selby, J. V., Borok, G. M., Henkin, L. F., Howard, G., Savage, P. J., Saad, M. F., et al. (1995) · Annals of Epidemiology · doi:10.1016/1047-2797(95)00062-3 · Cited by 494
Self-citation
Obesity in Children and Adolescents
Cali, A. M. G., & Caprio, S. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1363 · Cited by 453
Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus.
Ehrmann, D. A., Sturis, J., Byrne, M. M., Karrison, T., Rosenfield, R. L., & Polonsky, K. S. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118064 · Cited by 426
Insulin sensitivity and B-cell responsiveness to glucose during late pregnancy in lean and moderately obese women with normal glucose tolerance or mild gestational diabetes
Buchanan, T. A., Metzger, B. E., Freinkel, N., & Bergman, R. N. (1990) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(90)91306-w · Cited by 427
Self-citation
Abdominal fat distribution and metabolic risk factors: Effects of race
Lovejoy, J. C., de la Bretonne, J. A., Klemperer, M., & Tulley, R. T. (1996) · Metabolism · doi:10.1016/s0026-0495(96)90011-6 · Cited by 345
Indexes of Insulin Resistance and Secretion in Obese Children and Adolescents
Conwell, L. S., Trost, S. G., Brown, W. J., & Batch, J. (2004) · Diabetes Care · doi:10.2337/diacare.27.2.314 · Cited by 346
“Bergman, 1994) for determination of Si and acute insulin response (AIR) (an estimate of insulin secretory capacity) (19).”
Background
Pancreatic B-Cell Defects in Gestational Diabetes: Implications for the Pathogenesis and Prevention of Type 2 Diabetes
Buchanan, T. A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.3.7339 · Cited by 339
Methods for clinical assessment of insulin sensitivity and β-cell function
Pacini, G., & Mari, A. (2003) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/s1521-690x(03)00042-3 · Cited by 310
Assessing the Predictive Accuracy of QUICKI as a Surrogate Index for Insulin Sensitivity Using a Calibration Model
Chen, H., Sullivan, G., & Quon, M. J. (2005) · Diabetes · doi:10.2337/diabetes.54.7.1914 · Cited by 269
Relationship of dietary fat to glucose metabolism
Lichtenstein, A. H., & Schwab, U. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(99)00504-3 · Cited by 248
Monounsaturated Fat–Rich Diet Prevents Central Body Fat Distribution and Decreases Postprandial Adiponectin Expression Induced by a Carbohydrate-Rich Diet in Insulin-Resistant Subjects
Paniagua, J. A., de la Sacristana, A. G., Romero, I., Vidal‐Puig, A., Latre, J. M., Sánchez, E., Pérez‐Martínez, P., López‐Miranda, J., & Pérez‐Jiménez, F. (2007) · Diabetes Care · doi:10.2337/dc06-2220 · Cited by 242
Contribution of visceral fat mass to the insulin resistance of aging
Cefalu, W. T., Wang, Z. Q., Werbel, S. S., Bell–Farrow, A. D., Crouse, J. R., Hinson, W. H., Terry, J. G., & Anderson, R. L. (1995) · Metabolism · doi:10.1016/0026-0495(95)90251-1 · Cited by 228
Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance.
Cavaghan, M. K., Ehrmann, D. A., Byrne, M. M., & Polonsky, K. S. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119562 · Cited by 216
Insulin resistance, secretion, and elimination in postmenopausal women receiving oral or transdermal hormone replacement therapy
Godsland, I. F., GANGAR, K. F., Walton, C., Cust, M. P., Whitehead, M. I., Wynn, V., & Stevenson, J. C. (1993) · Metabolism · doi:10.1016/0026-0495(93)90058-v · Cited by 213
GENETICS OF NON-INSULIN-DEPENDENT (TYPE-II) DIABETES MELLITUS
Kahn, C. R., Vicent, D., & Doria, A. (1996) · Annual Review of Medicine · doi:10.1146/annurev.med.47.1.509 · Cited by 213
Review of methods for detecting glycemic disorders
Bergman, M., Abdul‐Ghani, M. A., DeFronzo, R. A., Manco, M., Sesti, G., Fiorentino, T. V., Ceriello, A., Rhee, M. K., Phillips, L. S., Chung, S. T., et al. (2020) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2020.108233 · Cited by 210
Dietary restriction and aging in rhesus monkeys: the University of Wisconsin study
Ramsey, J. J., Colman, R. J., Binkley, N., Christensen, J. D., Gresl, T. A., Kemnitz, J. W., & Weindruch, R. H. (2000) · Experimental Gerontology · doi:10.1016/s0531-5565(00)00166-2 · Cited by 199
Sleep and metabolic function
Morselli, L. L., Guyon, A., & Spiegel, K. (2012) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-011-1053-z · Cited by 199
INSULIN ACTION IN THE POLYCYSTIC OVARY SYNDROME
Dunaif, A. E. (1999) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70073-6 · Cited by 180
Nutrient–secretion coupling in the pancreatic islet β-cell: recent advances
Rutter, G. A. (2001) · Molecular Aspects of Medicine · doi:10.1016/s0098-2997(01)00013-9 · Cited by 180
PATHOGENESIS OF TYPE 2 DIABETES
Boden, G. H. (2001) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70216-4 · Cited by 173
Ethnic Differences in Insulin Sensitivity and β-Cell Function in Premenopausal or Early Perimenopausal Women Without Diabetes
Torréns, J. I., Skurnick, J., Davidow, A. L., Korenman, S. G., Santoro, N. F., Soto‐Greene, M. L., Lasser, N. L., & Weiss, G. (2004) · Diabetes Care · doi:10.2337/diacare.27.2.354 · Cited by 161
“who have normal glucose tolerance (1).”
Metformin as an Adjunct Therapy in Adolescents With Type 1 Diabetes and Insulin Resistance
Hamilton, J. K., Cummings, E. A., Zdravković, V., Finegood, D. T., & Daneman, D. (2003) · Diabetes Care · doi:10.2337/diacare.26.1.138 · Cited by 160
Glucose Homeostasis in Huntington Disease
Lalic, N. M., Marić, J., Svetel, M. V., Jotić, A., Stefanova, E. D., Lalic, K. S., Dragašević, N., Milicic, T. J., Lukić, L., & Kostić, V. (2008) · Archives of Neurology · doi:10.1001/archneur.65.4.476 · Cited by 150
“The PG and PI values obtained from the IVGTT were used to evaluate insulin sensitivity by means of minimal model analysis and to analyze early-phase insulin secretion by determining AIR (described in the third paragraph following).12,13 Minimal model analysis of insulin sensitivity was performed from the frequently sa…”
Influential
Altered D-Chiro-Inositol Urinary Clearance in Women With Polycystic Ovary Syndrome
Baillargeon, J., Diamanti‐Kandarakis, E., Ostlund, R. E., Apridonidze, T., Iuorno, M. J., & Nestler, J. E. (2006) · Diabetes Care · doi:10.2337/diacare.29.02.06.dc05-1070 · Cited by 147
Changes in Insulin Sensitivity, Secretion and Glucose Effectiveness During Menstrual Cycle
Pulido, J. M. E., & Salazar, M. A. (1999) · Archives of Medical Research · doi:10.1016/s0188-0128(98)00008-6 · Cited by 148
Angiotensin II infusion decreases plasma adiponectin level via its type 1 receptor in rats: an implication for hypertension-related insulin resistance
Ran, J., Hirano, T., Fukui, T., Saito, K., Kageyama, H., Okada, K., & Adachi, M. (2006) · Metabolism · doi:10.1016/j.metabol.2005.10.009 · Cited by 140
Impact of Sleep and Sleep Loss on Glucose Homeostasis and Appetite Regulation
Knutson, K. L. (2007) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2007.03.004 · Cited by 145
Liver-Derived IGF-I is of Importance for Normal Carbohydrate and Lipid Metabolism
Sjögren, K., Wallenius, K., Liu, J., Bohlooly‐Y, M., Pacini, G., Svensson, L., Törnell, J., Isaksson, O. G. P., Åhrén, B., Jansson, J., et al. (2001) · Diabetes · doi:10.2337/diabetes.50.7.1539 · Cited by 136
The Peroxisome Poliferator–Activated Receptor-γ2 Pro12Ala Variant
Douglas, J. A., Erdos, M. R., Watanabe, R. M., et al. (2001) · Diabetes · doi:10.2337/diabetes.50.4.886 · Cited by 133
Self-citation
Reduced Sleep Duration or Quality: Relationships With Insulin Resistance and Type 2 Diabetes
Tasali, E., Leproult, R., & Spiegel, K. (2009) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2008.10.002 · Cited by 129
Prenatal testosterone excess programs reproductive and metabolic dysfunction in the female
Padmanabhan, V., Manikkam, M., Recabarren, S. E., & Foster, D. L. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2005.11.016 · Cited by 119
Risk and mechanism of dexamethasone-induced deterioration of glucose tolerance in non-diabetic first-degree relatives of NIDDM patients
Alford, F., Beck-Nielsen, H., Ward, G. M., & Henriksen, J. E. (1997) · Diabetologia · doi:10.1007/s001250050847 · Cited by 115
Minimal Model-Based Insulin Sensitivity Has Greater Heritability and a Different Genetic Basis Than Homeostasis Model Assessment or Fasting Insulin
Bergman, R. N., Zaccaro, D. J., Watanabe, R. M., Haffner, S. M., Saad, M. F., Norris, J. M., Wagenknecht, L. E., Hokanson, J. E., Rotter, J. I., & Rich, S. S. (2003) · Diabetes · doi:10.2337/diabetes.52.8.2168 · Cited by 109
“It is the stereotypical hyperbolic relation between insulin secretion and action (40) that may account for the reflection of insulin sensitivity in the fasting insulin measure.”
Self-citation
Response of pancreatic beta-cells to improved insulin sensitivity in women at high risk for type 2 diabetes.
Buchanan, T. A., Xiang, A. H., Peters, R. K., Kjos, S. L., Berkowitz, K. M., Marroquin, A., Goico, J., Ochoa, C., & Azen, S. P. (2000) · Diabetes · doi:10.2337/diabetes.49.5.782 · Cited by 111
Acute hypoxia and exercise improve insulin sensitivity ( S I 2 *) in individuals with type 2 diabetes
Mackenzie, R., Maxwell, N., Castle, P., Brickley, G., & Watt, P. (2010) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.1156 · Cited by 115
“This relationship, represented by the disposition index (DI), can be calculated using the modelled parameters of insulin sensitivity (SI2∗) and acute insulin response to glucose (AIRg), is a physiological representation of the β cells’ compensatory response to changes in insulin sensitivity (SI2∗) [12].”
Method
Insulin resistance: a metabolic link between depressive disorder and atherosclerotic vascular diseases
Ramasubbu, R. (2002) · Medical Hypotheses · doi:10.1016/s0306-9877(02)00244-x · Cited by 105
Increased glucose effectiveness in normoglycemic but insulin-resistant relatives of patients with non-insulin-dependent diabetes mellitus. A novel compensatory mechanism.
Henriksen, J. E., ALFORD, F. P., Handberg, A., Vaag, A. A., Ward, G. M., Kalfas, A., & Beck‐Nielsen, H. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117436 · Cited by 107
A simulation model of glucose regulation in the critically ill
Hovorka, R., Chassin, L. J., Ellmerer, M., Plank, J., & Wilinska, M. E. (2008) · Physiological Measurement · doi:10.1088/0967-3334/29/8/008 · Cited by 102
Glucose Allostasis
Stümvoll, M., Tataranni, P. A., Stefan, N., de Courten, B. V., & Bogardus, C. (2003) · Diabetes · doi:10.2337/diabetes.52.4.903 · Cited by 116
Effect of a controlled high-fat versus low-fat diet on insulin sensitivity and leptin levels in African-American and Caucasian women.
Lovejoy, J. C., Windhauser, M. M., Rood, J., & de la Bretonne, J. A. (1998) · Metabolism: Clinical and Experimental · doi:10.1016/s0026-0495(98)90080-4 · Cited by 106
Mode of action of ipomoea batatas (caiapo) in type 2 diabetic patients
Ludvik, B. H., Waldhäusl, W. K., Prager, R., Kautzky‐Willer, A., & Pacini, G. (2003) · Metabolism · doi:10.1016/s0026-0495(03)00073-8 · Cited by 95
Direct Administration of Insulin Into Skeletal Muscle Reveals That the Transport of Insulin Across the Capillary Endothelium Limits the Time Course of Insulin to Activate Glucose Disposal
Chiu, J. D., Richey, J. M., Harrison, L. N., Zuniga, E. A., Kolka, C. M., Kirkman, E. L., Ellmerer, M., & Bergman, R. N. (2008) · Diabetes · doi:10.2337/db07-1444 · Cited by 96
“Previous conclusions regarding the time course of insulin diffusion through the endothelial barrier resulted from studies in which the time course of insulin in plasma was compared with the time course of glucose disposal (27).”
ResultSelf-citation
Retinol binding protein 4 as a candidate gene for type 2 diabetes and prediabetic intermediate traits
Craig, R. L., Chu, W. S., & Elbein, S. C. (2006) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2006.11.003 · Cited by 89
Actos Now for the prevention of diabetes (ACT NOW) study
DeFronzo, R. A., Banerji, M., Bray, G. A., Buchanan, T. A., Clement, S., Henry, R. R., Kitabchi, A. E., Mudaliar, S., Musi, N., Ratner, R., et al. (2009) · BMC Endocrine Disorders · doi:10.1186/1472-6823-9-17 · Cited by 89
Brain functional magnetic resonance imaging response to glucose and fructose infusions in humans
Purnell, J. Q., Klopfenstein, B. A., Stevens, A. A., Havel, P. J., Adams, S. H., Dunn, T. N., Krisky, C. M., & Rooney, W. D. (2010) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2010.01340.x · Cited by 91
The effect of oral metformin on insulin sensitivity in insulin-resistant ponies
Tinworth, K. D., Boston, R., Harris, P. A., Sillence, M. N., Raidal, S. L., & Noble, G. K. (2011) · The Veterinary Journal · doi:10.1016/j.tvjl.2011.01.015 · Cited by 82
Dietary restriction
Masoro, E. J. (1995) · Experimental Gerontology · doi:10.1016/0531-5565(94)00028-2 · Cited by 83
Association between the endothelin-1 gene Lys198Asn polymorphism blood pressure and plasma endothelin-1 levels in normal and pre-eclamptic pregnancy
Barden, A. E., Herbison, C. E., Beilin, L. J., Michael, C. A., Walters, B. N. J., & BOCKXMEER, F. M. V. (2001) · Journal of Hypertension · doi:10.1097/00004872-200110000-00011 · Cited by 82
Changes in Insulin Sensitivity in Response to Troglitazone Do Not Differ Between Subjects With and Without the Common, Functional Pro12Ala Peroxisome Proliferator–Activated Receptor-γ2 Gene Variant
Snitker, S., Watanabe, R. M., Ani, I., Xiang, A. H., Marroquin, A., Ochoa, C., Goico, J., Shuldiner, A. R., & Buchanan, T. A. (2004) · Diabetes Care · doi:10.2337/diacare.27.6.1365 · Cited by 82
“The study protocol included a tolbutamidemodified, frequently sampled intravenous glucose tolerance test (15) performed at baseline and repeated after 3 months of treatment.”
Influential
Type 2 diabetes and the metabolic syndrome in Japanese Americans
Fujimoto, W. Y., Bergstrom, R. W., Boyko, E. J., Chen, K.-W., Kahn, S. E., Leonetti, D. L., McNeely, M. J., Newell, L., Shofer, J. B., & WAHL, P. W. (2000) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(00)00182-0 · Cited by 76
Leptin and Leptin Receptor Gene Polymorphisms and Changes in Glucose Homeostasis in Response to Regular Exercise in Nondiabetic Individuals
Lakka, T. A., Rankinen, T., Weisnagel, S. J., Chagnon, Y. C., Lakka, H.-M., Ukkola, O. H., Boulé, N. G., Rice, T., Leon, A. S., Skinner, J. S., et al. (2004) · Diabetes · doi:10.2337/diabetes.53.6.1603 · Cited by 77
“Insulin sensitivity index (Si) and glucose effectiveness (Sg) were computed by a least-squares fitting of the temporal pattern of glucose and insulin throughout the FSIVGT using the MINMOD program (32).”
MethodSelf-citation
Compartmental models for glycaemic prediction and decision-support in clinical diabetes care: promise and reality
Lehmann, E. D., & Deutsch, T. (1998) · Computer Methods and Programs in Biomedicine · doi:10.1016/s0169-2607(98)00025-x · Cited by 71
Nonhuman Primate Calorie Restriction
Colman, R. J., & Anderson, R. M. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3224 · Cited by 72
Data-Driven Anomaly Recognition for Unsupervised Model-Free Fault Detection in Artificial Pancreas
Meneghetti, L., Terzi, M., Favero, S. D., Susto, G. A., & Cobelli, C. (2018) · IEEE Transactions on Control Systems Technology · doi:10.1109/tcst.2018.2885963 · Cited by 68
Measures of insulin sensitivity.
Bloomgarden, Z. (2006) · Clinics in Laboratory Medicine · doi:10.1016/j.cll.2006.06.007 · Cited by 65
The Effect of Ipomoea batatas (Caiapo) on Glucose Metabolism and Serum Cholesterol in Patients With Type 2 Diabetes
Ludvik, B. H., Mahdjoobian, K., Waldhaeusl, W., Hofer, A., Prager, R., Kautzky‐Willer, A., & Pacini, G. (2002) · Diabetes Care · doi:10.2337/diacare.25.1.239 · Cited by 65
Effects of weight loss on insulin sensitivity and arterial stiffness in overweight adults
Dengel, D. R., Kelly, A. S., Olson, T. P., Kaiser, D. R., Dengel, J. L., & Bank, A. J. (2006) · Metabolism · doi:10.1016/j.metabol.2006.02.018 · Cited by 64
Relationships between fibrinogen and insulin resistance
de Mauverger, É. R., Pérez‐Martin, A., Brun, J. ‐., Aı̈ssa-Benhaddad, A., Fédou, C., & Mercier, J. G. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(99)00373-1 · Cited by 62
Influence of caloric intake on aging and on the response to stressors
Masoro, E. J. (1998) · Journal of Toxicology and Environmental Health Part B · doi:10.1080/10937409809524554 · Cited by 60
Androgenicity and obesity are independently associated with insulin sensitivity in postmenopausal women
Lee, C. C., Kasa-Vubu, J. Z., & Supiano, M. A. (2004) · Metabolism · doi:10.1016/j.metabol.2003.10.018 · Cited by 60
Relationship of insulin clearance and secretion to insulin sensitivity in non‐diabetic Mexican Americans
Haffner, S. M., Stern, M. P., Watanabe, R. M., & Bergman, R. N. (1992) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.1992.tb01819.x · Cited by 60
Self-citation
Insulin Sensitivity in the Offspring of Women With Type 1 and Type 2 Diabetes
Hunter, W. A., Cundy, T., Rabone, D. L., Hofman, P. L., Harris, M. A., Regan, F. M., Robinson, E., & Cutfield, W. S. (2004) · Diabetes Care · doi:10.2337/diacare.27.5.1148 · Cited by 55
“Impaired glucose tolerance exists when there is a reduction in at least two of these three variables (16).”
Background
Control of glycaemia: from molecules to men. Minkowski Lecture 2003
Stümvoll, M. (2004) · Diabetologia · doi:10.1007/s00125-004-1400-0 · Cited by 54
Comparison of the minimal model and the hyperglycemic clamp for measuring insulin sensitivity and acute insulin response to glucose
Korytkowski, M. T., Berga, S. L., & Horwitz, M. J. (1995) · Metabolism · doi:10.1016/0026-0495(95)90003-9 · Cited by 52
Visfatin in human pregnancy: maternal gestational diabetesvis-à-visneonatal birthweight
Mazaki‐Tovi, S., Romero, R. J., Kusanovic, J. P., Vaisbuch, E., Erez, O., Than, N. G., Chaiworapongsa, T., Nhan‐Chang, C., Pacora, P., Gotsch, F., et al. (2008) · Journal of Perinatal Medicine · doi:10.1515/jpm.2009.053 · Cited by 53
Assessment and mathematical modeling of glucose turnover and insulin sensitivity in lean and obese cats
Hoenig, M. E., Thomaseth, K., Brandao, J., Waldron, M. K., & Ferguson, D. C. (2006) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2005.12.004 · Cited by 53
Insulin sensitivity, insulin secretion, and glucose effectiveness in anorexia nervosa: A minimal model analysis
Fukushima, M., Nakai, Y., Taniguchi, A., Imura, H., Nagata, I., & Tokuyama, K. (1993) · Metabolism · doi:10.1016/0026-0495(93)90275-s · Cited by 53
Heightened norepinephrine-mediated vasoconstriction in type 2 diabetes
Hogikyan, R. V., Gałecki, A. T., Halter, J. B., & Supiano, M. A. (1999) · Metabolism · doi:10.1016/s0026-0495(99)90242-1 · Cited by 54
Association between a deletion/insertion polymorphism in the ?2B-adrenergic receptor gene and insulin secretion and Type 2 diabetes. The Finnish Diabetes Prevention Study
Siitonen, N., Lindstr�m, J., Eriksson, J. G., Valle, T. T., H�m�l�inen, H., Ilanne‐Parikka, P., Kein�nen-Kiukaanniemi, S., Tuomilehto, J. O., Laakso, M., & Uusitupa, M. I. J. (2004) · Diabetologia · doi:10.1007/s00125-004-1462-z · Cited by 53
Evidence for pancreatic β-cell dysfunction in brothers of women with polycystic ovary syndrome
Sam, S., Sung, Y., Legro, R. S., & Dunaif, A. E. (2007) · Metabolism · doi:10.1016/j.metabol.2007.08.010 · Cited by 48
B-type natriuretic peptide (BNP) affects the initial response to intravenous glucose: a randomised placebo-controlled cross-over study in healthy men
Heinisch, B. B., Vila, G., Resl, M., Riedl, M., Dieplinger, B., Mueller, T., Luger, A., Pacini, G., & Clodi, M. (2011) · Diabetologia · doi:10.1007/s00125-011-2392-1 · Cited by 49
Ethnic heterogeneity in glucoregulatory function during treatment with atypical antipsychotics in patients with schizophrenia
Ader, M., Garvey, W. T., Phillips, L. S., Nemeroff, C. B., Gharabawi, G. M., Mahmoud, R. A., Greenspan, A. J., Berry, S. A., Musselman, D. L., Morein, J., et al. (2008) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2008.01.004 · Cited by 48
Self-citation
Abdominal Adiposity Assessed by Dual Energy X-Ray Absorptiometry Provides a Sex-Independent Predictor of Insulin Sensitivity in Older Adults
Lee, C. C., Glickman, S. G., Dengel, D. R., Brown, M. D., & Supiano, M. A. (2005) · The Journals of Gerontology Series A · doi:10.1093/gerona/60.7.872 · Cited by 48
Measurement of insulin resistance in chronic kidney disease
Pham, H., Utzschneider, K., & de Boer, I. D. (2011) · Current opinion in nephrology and hypertension · doi:10.1097/mnh.0b013e32834b23c1 · Cited by 50
The Finland–United States Investigation of Non–Insulin‐Dependent Diabetes Mellitus Genetics (FUSION) Study. II. An Autosomal Genome Scan for Diabetes‐Related Quantitative‐Trait Loci
Watanabe, R. M., Ghosh, S., Langefeld, C. D., Valle, T. T., Hauser, E. R., Magnuson, V. L., Mohlke, K. L., Silander, K., Ally, D. S., Chines, P. S., et al. (2000) · The American Journal of Human Genetics · doi:10.1086/321184 · Cited by 48
Self-citation
Advancing Our Understanding of the Glucose System via Modeling: A Perspective
Cobelli, C., Dalla Man, C., Pedersen, M. G., Bertoldo, A., & Toffolo, G. (2014) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2014.2310514 · Cited by 46
The hyperbolic equilibrium between insulin sensitivity and secretion
Pacini, G. (2006) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2005.10.014 · Cited by 46
Nutritional effects of oral zinc supplementation in cirrhosis
Bianchi, G. P., Marchesini, G., Brizi, M., Rossi, B., Forlani, G., Boni, P., Melchionda, N., Thomaseth, K., & Pacini, G. (2000) · Nutrition Research · doi:10.1016/s0271-5317(00)00194-9 · Cited by 44
Insulin resistance and fat patterning with aging: Relationship to metabolic risk factors for cardiovascular disease
Cefalu, W. T., Werbel, S. S., Bell–Farrow, A. D., Terry, J. G., Wang, Z. O., Opara, E. C., Morgan, T., Hinson, W. H., & Crouse, J. R. (1998) · Metabolism · doi:10.1016/s0026-0495(98)90050-6 · Cited by 43
Effects of acute exercise on insulin sensitivity, glucose effectiveness and disposition index in type 2 diabetic patients
Bordenave, S., Brandou, F., Manetta, J., Fédou, C., Mercier, J. G., & Brun, J. ‐. (2008) · Diabetes & Metabolism · doi:10.1016/j.diabet.2007.12.008 · Cited by 42
Hemoglobin A1c (HbA1c) predicts future drug treatment for diabetes mellitus: a follow-up study using routine clinical data in a Japanese university hospital
Shimazaki, T., Kadowaki, T., Ohyama, Y., Ohe, K., & Kubota, K. (2007) · Translational research · doi:10.1016/j.trsl.2006.09.008 · Cited by 42
Evaluation of insulin sensitivity and glucose effectiveness during a standardized breakfast test: comparison with the minimal model analysis of an intravenous glucose tolerance test
Aloulou, I., Brun, J. ‐., & Mercier, J. G. (2006) · Metabolism · doi:10.1016/j.metabol.2006.01.002 · Cited by 45
Resistencia a la insulina y su implicación en múltiples factores de riesgo asociados a diabetes tipo 2
Serrano‐Ríos, M. (2002) · Medicina Clínica · doi:10.1016/s0025-7753(02)73455-6 · Cited by 42
The effects of hormonal replacement therapy on insulin sensitivity in surgically postmenopausal cynomolgus monkeys (Macaca fascicularis)
Cefalu, W. T., Wagner, J. D., Bell–Farrow, A. D., Wang, Z. Q., Adams, M. R., TOFFOLO, G. M., & Cobelli, C. (1994) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(94)90280-1 · Cited by 40
A trajectory splicing approach to concretizing counterexamples for hybrid systems
Zutshi, A., Sankaranarayanan, S., Deshmukh, J. V., et al. (2013) · Proceedings of the IEEE Conference on Decision & Control, including the Symposium on Adaptive Processes · doi:10.1109/cdc.2013.6760488 · Cited by 39
Estimation of plasma insulin from plasma glucose
Neatpisarnvanit, C., & Boston, J. R. (2002) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2002.804599 · Cited by 37
Insulin sensitivity, insulin secretion, and glucose effectiveness in subjects with impaired glucose tolerance: A minimal model analysis
Taniguchi, A., Nakai, Y., Fukushima, M., Imura, H., Kawamura, H., Nagata, I., Florant, G. L., & Tokuyama, K. (1994) · Metabolism · doi:10.1016/0026-0495(94)90119-8 · Cited by 36
Schizophrenia and diabetes
Henderson, D. C., & Ettinger, E. R. (2002) · International review of neurobiology · doi:10.1016/s0074-7742(02)51014-x · Cited by 36
Model-Based Detection and Classification of Insulin Pump Faults and Missed Meal Announcements in Artificial Pancreas Systems for Type 1 Diabetes Therapy
Meneghetti, L., Facchinetti, A., & Favero, S. D. (2020) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2020.3004270 · Cited by 38
Influence of body fatness on the coronary risk profile of physically active postmenopausal women
Tanaka, H., Clevenger, C. M., Jones, P. P., Seals, D. R., & DeSouza, C. A. (1998) · Metabolism · doi:10.1016/s0026-0495(98)90286-4 · Cited by 35
The Minimal Model of Glucose Regulation: A Biography
Bergman, R. N. (2003) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-9019-8_1 · Cited by 41
Self-citation

Authors: Bergman, R. N.
Corresponding author: Bergman, R. N.
ORCID: Bergman, R. N.
Venue: Diabetes
Publisher: American Diabetes Association
Published: 1989-12-01
Volume: 38
Issue: 12
Pages: 1512-1527
ISSN: 0012-1797 (ISSN-L)
DOI: 10.2337/diabetes.38.12.1512
OpenAlex: W4229511887
Cited by: 215
References: 0
Citations by year: 2025: 4 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 5 · 2018: 2 · 2017: 2 · 2016: 1 · 2014: 5 · 2013: 4 · 2012: 5
FWCI: 2.33
Type: journal article
Language: en
Open access: closed
Locations: Diabetes (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pancreatic function and diabetes
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords: glucose tolerance, minimal models, glucose metabolism, insulin sensitivity, insulin secretion

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Lilly lecture 1989. Toward physiological understanding of glucose tolerance. Minimal-model approach

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cited by

Related

Metadata

Record

About these checks