Cited by 300Nitric Oxide and Endothelin EffectsAldose Reductase and TaurineBiochemical Acid Research Studies

The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.

Effect of Antioxidant Treatment of Streptozotocin-Induced Diabetic Rats on Endoneurial Blood Flow, Motor Nerve Conduction Velocity, and Vascular Reactivity of Epineurial Arterioles of the Sciatic Nerve

Open access

Coppey, Lawrence J., Gellett, Jill S., Davidson, Eric P., Dunlap, Joyce A., Lund, Donald D., Yorek, Mark A.·2001·Diabetes

DOI 10.2337/diabetes.50.8.1927

Open this paper in CoChat — free account Open PDF

Abstract

We have shown that diabetes-induced reduction in endoneurial blood flow (EBF) and impaired endothelium-dependent vascular relaxation precede slowing of motor nerve conduction velocity (MNCV) and decreased sciatic nerve Na+/K+ ATPase activity. Furthermore, vascular dysfunction was accompanied by an accumulation of superoxide in arterioles that provide circulation to the sciatic nerve. In the present study, we examined the effect that treatment of streptozotocin-induced diabetic rats with antioxidants has on vascular and neural function. Diabetic rats were treated with 0.5% α-lipoic acid as a diet supplement or with hydroxyethyl starch deferoxamine (HES-DFO) by weekly intravenous injections at a dose of 75 mg/kg. The treatments significantly improved diabetes-induced decrease in EBF, acetylcholine-mediated vascular relaxation in arterioles that provide circulation to the region of the sciatic nerve, and MNCV. The treatments also reduced the production of superoxide by the aorta and superoxide and peroxynitrite by arterioles that provide circulation to the region of the sciatic nerve. Treating diabetic rats with α-lipoic acid prevented the diabetes-induced increase in thiobarbituric acid–reactive substances in serum and significantly improved lens glutathione levels. In contrast, treating diabetic rats with HES-DFO did not prevent diabetes-induced changes of either of these markers of oxidative stress. Diabetes-induced increase in sciatic nerve conjugated diene levels was not improved by treatment with either α-lipoic acid or HES-DFO. Treating diabetic rats with α-lipoic acid but not HES-DFO partially improved sciatic nerve Na+/K+ ATPase activity and myo-inositol content. The increase in sciatic nerve sorbitol levels in diabetic rats was unchanged by either treatment. These studies suggest that diabetes-induced oxidative stress and the generation of superoxide may be partially responsible for the development of diabetic vascular and neural complications.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.2337/diabetes.50.8.1927

Cites

65 of 65 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
Nishikawa, T., Edelstein, D., Du, X. L., Yamagishi, S.-I., Matsumura, T., Kaneda, Y., Yorek, M. A., Beebe, D., Oates, P. J., Hammes, H.-P., et al. (2000) · Nature · doi:10.1038/35008121 · Cited by 4,277
Self-citation
Role of oxidative stress in diabetic complications: a new perspective on an old paradigm.
Baynes, J. W., & Thorpe, S. R. (1999) · Diabetes · doi:10.2337/diabetes.48.1.1 · Cited by 2,441
Oxidative Stress and Diabetic Vascular Complications
Giugliano, D., Ceriello, A., & Paolisso, G. (1996) · Diabetes Care · doi:10.2337/diacare.19.3.257 · Cited by 1,921
The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide
Pryor, W. A., & Squadrito, G. L. (1995) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1995.268.5.l699 · Cited by 1,511 · cited 1×
“Peroxynitrite is a highly reactive intermediate known to nitrate protein tyrosine residues and cause cellular oxidative damage (39,40).”
Background
What is oxidative stress?
Betteridge, D. J. (2000) · Metabolism · doi:10.1016/s0026-0495(00)80077-3 · Cited by 1,475
Mechanisms Underlying Endothelial Dysfunction in Diabetes Mellitus
Hink, U., Li, H., Mollnau, H., Oelze, M., Matheis, E., Hartmann, M., Skatchkov, M. P., Thaiss, F., Stahl, R. A. K., Warnholtz, A., et al. (2001) · Circulation Research · doi:10.1161/01.res.88.2.e14 · Cited by 1,191
Endothelial dysfunction in diabetes
De Vriese, A. S., Verbeuren, T. J., Van de Voorde, J., Lameire, N. H., & Vanhoutte, P. M. (2000) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703393 · Cited by 1,165
Cellular and molecular mechanisms of endothelial cell dysfunction.
Harrison, D. G. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119751 · Cited by 1,059
Oxidative Damage and Tyrosine Nitration from Peroxynitrite
Beckman, J. S. (1996) · Chemical Research in Toxicology · doi:10.1021/tx9501445 · Cited by 993
Radicals and oxidative stress in diabetes
West, I. C. (2000) · Diabetic Medicine · doi:10.1046/j.1464-5491.2000.00259.x · Cited by 913

Show all 63 references

Sorted by citations

Items 101–200 of 300

Sensory Nerve Innervation of Epineurial Arterioles of the Sciatic Nerve Containing Calcitonin Gene–Related Peptide: Effect of Streptozotocin‐Induced Diabetes
Yorek, M. A., Coppey, L. J., Gellett, J. S., & Davidson, E. P. (2004) · Journal of Diabetes Research · doi:10.1080/15438600490486732 · Cited by 56
Self-citation
Design, optimization, and in-vivo performance of glipizide-loaded O-carboxymethyl chitosan nanoparticles in insulin resistant/type 2 diabetic rat model
El‐Dakroury, W. A., Zewail, M. B., & Amin, M. M. (2022) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2022.104040 · Cited by 55
Treatment of Zucker diabetic fatty rats with AVE7688 improves vascular and neural dysfunction
Oltman, C. L., Davidson, E. P., Coppey, L. J., Kleinschmidt, T. L., & Yorek, M. A. (2008) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2008.00924.x · Cited by 54
Self-citation
Animal models and biomarkers of neuropathy in diabetic rodents
Somani, R., & Shaikh, A. (2010) · Indian Journal of Pharmacology · doi:10.4103/0253-7613.66833 · Cited by 54
Baicalin Improves Antioxidant Status of Streptozotocin-Induced Diabetic Wistar Rats
Waisundara, V. Y., Hsu, A., Tan, B. K., & Huang, D. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf8028539 · Cited by 53
Elevated plasma adiponectin and decreased plasma homocysteine and asymmetric dimethylarginine in children with type 1 diabetes
Heilman, K., Zilmer, M., Zilmer, K., Kool, P., & Tillmann, V. (2008) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365510802419454 · Cited by 53
Dual Delivery of NGF and bFGF Coacervater Ameliorates Diabetic Peripheral Neuropathy via Inhibiting Schwann Cells Apoptosis
Li, R., Ma, J., Wu, Y., Nangle, M. R., Zou, S., Li, Y., Yin, J., Zhao, Y., Xu, H., Zhang, H., et al. (2017) · International Journal of Biological Sciences · doi:10.7150/ijbs.18636 · Cited by 53
Effect of inhibition of angiotensin converting enzyme and/or neutral endopeptidase on vascular and neural complications in high fat fed/low dose streptozotocin-diabetic rats
Davidson, E. P., Coppey, L. J., Holmes, A. J., & Yorek, M. A. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2011.12.003 · Cited by 52
Self-citation
Different Roles of 12/15-Lipoxygenase in Diabetic Large and Small Fiber Peripheral and Autonomic Neuropathies
Obrosova, I. G., Stavniichuk, R., Drel, V. R., Shevalye, H., Vareniuk, І., Nadler, J. L., & Schmidt, R. E. (2010) · American Journal Of Pathology · doi:10.2353/ajpath.2010.100178 · Cited by 54
Understanding and treating ejaculatory dysfunction in men with diabetes mellitus
Desai, A., Chen, R., Cayetano-Alcaráz, A. A., Jayasena, C. N., & Minhas, S. (2022) · Andrology · doi:10.1111/andr.13262 · Cited by 54
Protection of Trigonelline on Experimental Diabetic Peripheral Neuropathy
Zhou, J., & Zhou, S.-W. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/164219 · Cited by 51
Early Endothelial Dysfunction Severely Impairs Skin Blood Flow Response to Local Pressure Application in Streptozotocin-Induced Diabetic Mice
Sigaudo‐Roussel, D., Demiot, C., Fromy, B., Koı̈tka, A., Lefthériotis, G., Abraham, P., & Saumet, J. L. (2004) · Diabetes · doi:10.2337/diabetes.53.6.1564 · Cited by 60
Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies
Stavniichuk, R., Drel, V. R., Shevalye, H., Vareniuk, І., Stevens, M. J., Nadler, J. L., & Obrosova, I. G. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.06.016 · Cited by 50
Anti-hyperglycaemic and anti-hyperlipidaemic effects of black and red rice in streptozotocin-induced diabetic rats
Tantipaiboonwong, P., Pintha, K., Chaiwangyen, W., Chewonarin, T., Pangjit, K., Chumphukam, O., Kangwan, N., & Suttajit, M. (2017) · ScienceAsia · doi:10.2306/scienceasia1513-1874.2017.43.281 · Cited by 50
Alphalipoic Acid Prevents Oxidative Stress and Peripheral Neuropathy in Nab-Paclitaxel-Treated Rats through the Nrf2 Signalling Pathway
Sun, H., Guo, X., Wang, Z., Wang, P., Zhang, Z., Dong, J., Zhuang, R., Zhou, Y., Ma, G., & Cai, W. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/3142732 · Cited by 50
Understanding the role of hyperglycemia and the molecular mechanism associated with diabetic neuropathy and possible therapeutic strategies
Kaur, M., Misra, S., Swarnkar, P., Patel, P., Kurmi, B. D., Gupta, G. D., & Singh, A. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115723 · Cited by 49
Oxidative stress and autonomic nerve function in early type 1 diabetes
Hoeldtke, R. D., Bryner, K. D., & VanDyke, K. (2010) · Clinical Autonomic Research · doi:10.1007/s10286-010-0084-4 · Cited by 48
Impact of antioxidants on seminal vesicles function and fertilizing potential in diabetic rats
Honda, M., Tsounapi, P., Dimitriadis, F., Kawamoto, B., Hikita, K., Muraoka, K., Saito, M., Sofikitis, N., & Takenaka, A. (2016) · Asian Journal of Andrology · doi:10.4103/1008-682x.186871 · Cited by 48
Protective effects of 4-amino1,8-napthalimide, a poly (ADP-ribose) polymerase inhibitor in experimental diabetic neuropathy
Sharma, S. S., Kumar, A., & Kaundal, R. K. (2008) · Life Sciences · doi:10.1016/j.lfs.2007.11.031 · Cited by 48
Qualitative and quantitative determination of the caffeoylquinic acids on the Korean mountainous vegetables used for Chwinamul and their peroxynitrite-scavenging effect
Nugroho, A., Kim, K. H., Lee, K. R., Alam, M. B., Choi, J. S., Kim, W. B., & Park, H.-J. (2009) · Archives of Pharmacal Research · doi:10.1007/s12272-009-2003-6 · Cited by 46
Evaluation of the peroxynitrite decomposition catalyst Fe(III) tetra-mesitylporphyrin octasulfonate on peripheral neuropathy in a mouse model of type 1 diabetes
Drel, V. R., Pacher, P., Vareniuk, І., Pavlov, I. A., Ilnytska, O., Lyzogubov, V. V., Bell, S. R., Groves, J. T., & Obrosova, I. G. (2007) · International Journal of Molecular Medicine · doi:10.3892/ijmm.20.6.783 · Cited by 45
Mesenchymal Stem Cell-Like Cells Derived from Mouse Induced Pluripotent Stem Cells Ameliorate Diabetic Polyneuropathy in Mice
Himeno, T., Kamiya, H., Naruse, K., Cheng, Z., Ito, S., Kondo, M., Okawa, T., Fujiya, A., Kato, J., Suzuki, H., et al. (2013) · BioMed Research International · doi:10.1155/2013/259187 · Cited by 44
Selenium Treatment Protects Diabetes-Induced Biochemical and Ultrastructural Alterations in Liver Tissue
Can, B., Ulusu, N. N., Kılınç, K., Açan, N. L., Saran, Y., & Turan, B. (2005) · Biological Trace Element Research · doi:10.1385/bter:105:1-3:135 · Cited by 43
Cardioprotective effect of selenium via modulation of cardiac ryanodine receptor calcium release channels in diabetic rat cardiomyocytes through thioredoxin system
Okatan, E. N., Tuncay, E., & Turan, B. (2013) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2013.08.002 · Cited by 43
γ-Linolenic Acid versus α-Lipoic Acid for Treating Painful Diabetic Neuropathy in Adults: A 12-Week, Double-Placebo, Randomized, Noninferiority Trial
Won, J. C., Kwon, H., Moon, S., Chun, S. W., Kim, C. H., Park, I. B., Kim, I. J., Lee, J., Cha, B. Y., & Park, T. S. (2019) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2019.0099 · Cited by 46
EFFECTS OF TROLOX ON NERVE DYSFUNCTION, THERMAL HYPERALGESIA AND OXIDATIVE STRESS IN EXPERIMENTAL DIABETIC NEUROPATHY
Sharma, S. S., & Sayyed, S. G. (2006) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2006.04481.x · Cited by 43
Dietary supplementation with astaxanthin may ameliorate sperm parameters and DNA integrity in streptozotocin-induced diabetic rats
Bahmanzadeh, M., Vahidinia, A., Mehdinejadiani, S., Shokri, S., & Alizadeh, Z. (2016) · Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine · doi:10.5653/cerm.2016.43.2.90 · Cited by 42
Oxidative Stress in Diabetes Mellitus: Is There a Role for Hypoglycemic Drugs and/or Antioxidants?
Erejuwa, O. O. (2012) · InTech eBooks · doi:10.5772/32741 · Cited by 41
Treatment of Streptozotocin-Induced Diabetic Rats With AVE7688, a Vasopeptidase Inhibitor
Davidson, E. P., Kleinschmidt, T. L., Oltman, C. L., Lund, D. D., & Yorek, M. A. (2007) · Diabetes · doi:10.2337/db06-1180 · Cited by 42
Self-citation
Transforming growth factor-β induces cellular injury in experimental diabetic neuropathy
Anjaneyulu, M., Berent‐Spillson, A., Inoue, T., Choi, J., Cherian, K., & Russell, J. W. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.02.011 · Cited by 41
Interplay of sorbitol pathway of glucose metabolism, 12/15-lipoxygenase, and mitogen-activated protein kinases in the pathogenesis of diabetic peripheral neuropathy
Stavniichuk, R., Shevalye, H., Hirooka, H., Nadler, J. L., & Obrosova, I. G. (2012) · Biochemical Pharmacology · doi:10.1016/j.bcp.2012.01.015 · Cited by 38
Are Diabetic Neuropathy, Retinopathy and Nephropathy Caused by Hyperglycemic Exclusion of Dehydroascorbate Uptake by Glucose Transporters?
Root-Bernstein, R. S., Busik, J. V., & Henry, D. N. (2002) · Journal of Theoretical Biology · doi:10.1006/jtbi.2002.2535 · Cited by 38
Biological Trace Element Research
(2013) · Biological Trace Element Research · doi:10.1007/12011.1559-0720 · Cited by 39
Effect of combination therapy consisting of enalapril, α-lipoic acid, and menhaden oil on diabetic neuropathy in a high fat/low dose streptozotocin treated rat
Davidson, E. P., Holmes, A. J., Coppey, L. J., & Yorek, M. A. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.08.015 · Cited by 38
Self-citation
Efficacy of Evolvulus alsinoides (L.) L. on insulin and antioxidants activity in pancreas of streptozotocin induced diabetic rats
Gomathi, D., Ravikumar, G., Kalaiselvi, M., Devaki, K., & Uma, C. (2013) · Journal of Diabetes & Metabolic Disorders · doi:10.1186/2251-6581-12-39 · Cited by 38
Efficacy of α-Lipoic Acid Against Diabetic Cataract in Rat
Kojima, M., Sun, L., Hata, I., Sakamoto, Y., Sasaki, H., & Sasaki, K. (2007) · Japanese Journal of Ophthalmology · doi:10.1007/s10384-006-0384-3 · Cited by 36
R-(+)-α-lipoic acid inhibits endothelial cell apoptosis and proliferation: involvement of Akt and retinoblastoma protein/E2F-1
Artwohl, M., Muth, K., Kosulin, K., de Martin, R., Hölzenbein, T., Rainer, G., Freudenthaler, A., Huttary, N., Schmetterer, L. F., Waldhäusl, W. K., et al. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00584.2006 · Cited by 36
N-acetylcysteine Prevents Nitrosative Stress-Associated Depression of Blood Pressure and Heart Rate in Streptozotocin Diabetic Rats
Nagareddy, P. R., Xia, Z., MacLeod, K. M., & McNeill, J. H. (2006) · Journal of Cardiovascular Pharmacology · doi:10.1097/01.fjc.0000211744.93701.25 · Cited by 35
Evaluation of PMI-5011, an ethanolic extract of Artemisia dracunculus L., on peripheral neuropathy in streptozotocin-diabetic mice
Obrosova (2011) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2011.597 · Cited by 36
Impaired Corneal Sensation and Nerve Loss in a Type 2 Rat Model of Chronic Diabetes Is Reversible With Combination Therapy of Menhaden Oil, α-Lipoic Acid, and Enalapril
Davidson, E. P., Coppey, L. J., Shevalye, H., Obrosov, A. A., Kardon, R. H., & Yorek, M. A. (2017) · Cornea · doi:10.1097/ico.0000000000001182 · Cited by 35
Self-citation
Peroxynitrite versusnitric oxide in early diabetes
Hoeldtke, R. D. (2003) · American Journal of Hypertension · doi:10.1016/s0895-7061(03)00976-2 · Cited by 35
Retracted
Treatment of Streptozotocin-Induced Diabetic Rats with Alogliptin: Effect on Vascular and Neural Complications
Davidson, E. P., Coppey, L. J., Dake, B. L., & Yorek, M. A. (2011) · Experimental Diabetes Research · doi:10.1155/2011/810469 · Cited by 34
Self-citation
Effect of Treatment of Sprague Dawley Rats with AVE7688, Enalapril, or Candoxatril on Diet-Induced Obesity
Davidson, E. P., Coppey, L. J., Dake, B. L., & Yorek, M. A. (2010) · Journal of Obesity · doi:10.1155/2011/686952 · Cited by 33
Self-citation
Gender related differential effects of Omega-3E treatment on diabetes-induced left ventricular dysfunction
Tuncay, E., Seymen, A., Tanriverdi, E., Yaraş, N., Tandoğan, B., Ulusu, N. N., & Turan, B. (2007) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-007-9508-4 · Cited by 33
Evaluation of effect of alcoholic extract of heartwood of Pterocarpus marsupium on in vitro antioxidant, anti-glycation, sorbitol accumulation and inhibition of aldose reductase activity
Gupta, P. K., Jain, V., Pareek, A., Kumari, P., Singh, R., Agarwal, P., & Sharma, V. (2016) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2016.11.001 · Cited by 33
Minocycline with aspirin: a therapeutic approach in the treatment of diabetic neuropathy
Bhatt, L. K., & Veeranjaneyulu, A. (2010) · Neurological Sciences · doi:10.1007/s10072-010-0243-3 · Cited by 33
Reactive oxygen species mediate abnormal contractile response to sympathetic nerve stimulation and noradrenaline in the vas deferens of chronically diabetic rats: effects of in vivo treatment with antioxidants
Güneş, A., Ceylan, A. F., Sarıoğlu, Y., Štefek, M., Bauer, V., Karasu, Ç., & The Antioxidants in Diabetes‐induced Complications (ADIC) Study Group (2004) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.2004.00312.x · Cited by 33
Astragalus membranaceus and Panax notoginseng, the Novel Renoprotective Compound, Synergistically Protect against Podocyte Injury in Streptozotocin-Induced Diabetic Rats
Zhai, R., Jian, G., Chen, T., Xie, L., Xue, R., Gao, C., Wang, N., Xu, Y., & Gui, D. (2019) · Journal of Diabetes Research · doi:10.1155/2019/1602892 · Cited by 32
Progressive Loss of Corneal Nerve Fibers and Sensitivity in Rats Modeling Obesity and Type 2 Diabetes Is Reversible with Omega-3 Fatty Acid Intervention: Supporting Cornea Analyses as a Marker for Peripheral Neuropathy and Treatment
Coppey, L. J., Davidson, E. P., Shevalye, H., Obrosov, A. A., Torres, M. E., & Yorek, M. A. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s247571 · Cited by 33
Self-citation
The Metal Chelators, Trientine and Citrate, Inhibit the Development of Cardiac Pathology in the Zucker Diabetic Rat
Baynes, J., & Murray, D. B. (2009) · Experimental Diabetes Research · doi:10.1155/2009/696378 · Cited by 32
Alpha-lipoic Acid After Median Nerve Decompression at the Carpal Tunnel: A Randomized Controlled Trial
Boriani, F., Granchi, D., Roatti, G., Merlini, L., Sabattini, T., & Baldini, N. (2017) · The Journal Of Hand Surgery · doi:10.1016/j.jhsa.2017.01.011 · Cited by 32
Protection against oxidative stress in diabetic rats: Role of angiotensin AT1 receptor and beta 1-adrenoceptor antagonism
Dorenkamp, M., Riad, A., Stiehl, S., Spillmann, F., Westermann, D., Du, J., Pauschinger, M., Noutsias, M., Adams, V., Schultheiss, H., et al. (2005) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2005.07.020 · Cited by 32
Mediation of Vascular Relaxation in Epineurial Arterioles of the Sciatic Nerve: Effect of Diabetes in Type 1 and Type 2 Diabetic Rat Models
Coppey, L. J., Gellett, J. S., & Yorek, M. A. (2003) · Endothelium · doi:10.1080/10623320303366 · Cited by 32
Self-citation
Vascular Impairment of Epineurial Arterioles of the Sciatic Nerve: Implications for Diabetic Peripheral Neuropathy
Yorek, M. A. (2015) · The Review of Diabetic Studies · doi:10.1900/rds.2015.12.13 · Cited by 31
Self-citation
Peripheral Nerve Regeneration Is Independent From Schwann Cell p75NTR Expression
Gonçalves, N. P., Mohseni, S., Soury, M. E., Ulrichsen, M., Richner, M., Xiao, J., Wood, R. J., Andersen, O. M., Coulson, E. J., Raimondo, S., et al. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00235 · Cited by 32
Influence of selenium (antioxidant) on gliclazide induced hypoglycaemia/anti hyperglycaemia in normal/alloxan-induced diabetic rats
Satyanarayana, S., Sekhar, J. R., Kilari, E. K., Shannika, L. B., Rajanna, B., & Rajanna, S. (2006) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-006-2387-2 · Cited by 31
Sulphur mustard induces time- and concentration-dependent regulation of NO-synthesizing enzymes
Steinritz, D., Elischer, A., Balszuweit, F., Gonder, S., Heinrich, A., Bloch, W., Thiermann, H., & Kehe, K. (2009) · Toxicology Letters · doi:10.1016/j.toxlet.2009.04.012 · Cited by 30
Cellular and molecular mechanisms of acute exposure to sulfur mustard: a systematic review
Nourani, M. R., Hosseini, H. M., Jamalkandi, S. A., & Fooladi, A. A. I. (2016) · Journal of Receptors and Signal Transduction · doi:10.1080/10799893.2016.1212374 · Cited by 32
Early vs. late intervention of high fat/low dose streptozotocin treated C57Bl/6J mice with enalapril, α-lipoic acid, menhaden oil or their combination: Effect on diabetic neuropathy related endpoints
Yorek, M. S., Obrosov, A. A., Shevalye, H., Coppey, L. J., Kardon, R. H., & Yorek, M. A. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.12.022 · Cited by 30
Self-citation
Local blood flow in peripheral nerves and their ganglia: Resurrecting key ideas around its measurement and significance
Zochodne, D. W. (2017) · Muscle & Nerve · doi:10.1002/mus.26031 · Cited by 30
Resveratrol, a polyphenolic phytoalexin attenuates thermal hyperalgesia and cold allodynia in STZ-induced diabetic rats.
Sharma, S., Kulkarni, S., & Chopra, K. (2006) · PubMed · Cited by 30
Sorbinil, an Aldose Reductase Inhibitor, in Fighting Against Diabetic Complications
Huang, Q., Liu, Q., & Ouyang, D. (2018) · Medicinal Chemistry · doi:10.2174/1573406414666180524082445 · Cited by 29
Effect of mitoquinone (Mito-Q) on neuropathic endpoints in an obese and type 2 diabetic rat model
Fink, B. D., Coppey, L. J., Davidson, E. P., Shevalye, H., Obrosov, A. A., Chheda, P. R., Kerns, R. J., Sivitz, W. I., & Yorek, M. A. (2020) · Free Radical Research · doi:10.1080/10715762.2020.1754409 · Cited by 31
Self-citation
The Use and Alpha-Lipoic Acid (ALA), Gamma Linolenic Acid (GLA) and Rehabilitation in the Treatment of Back Pain: Effect on Health-Related Quality of Life
Ranieri, M., Sciuscio, M., Cortese, A. M., Santamato, A., Teo, L.-M., Ianieri, G., Rg, B., Stasi, M., & Megna, M. (2009) · International Journal of Immunopathology and Pharmacology · doi:10.1177/03946320090220s309 · Cited by 29
Preventive effect of l-carnosine on changes in the thermal nociceptive threshold in streptozotocin-induced diabetic mice
Kamei, J., Ohsawa, M., Miyata, S., & Tanaka, S. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.10.002 · Cited by 28
Berberine Decreased Inducible Nitric Oxide Synthase mRNA Stability through Negative Regulation of Human Antigen R in Lipopolysaccharide-Induced Macrophages
Shin, J., Choi, H.-E., Seo, S., Choi, J., Baek, N., & Lee, K.-T. (2016) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.115.231043 · Cited by 28
α-Lipoic acid treatment prevents the diabetes-induced attenuation of the afferent limb of the baroreceptor reflex in rats
Gouty, S., Regalia, J., Cai, F., & Helke, C. J. (2003) · Autonomic Neuroscience · doi:10.1016/j.autneu.2003.08.004 · Cited by 28
Characterization of Streptozotocin-induced Diabetic Rats and Pharmacodynamics of Insulin Formulations
Lee, J.-J., Ho-Young, Y. I., Yang, J., Shin, J., Kwon, J.-H., & Kim, C. (2003) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.67.2396 · Cited by 28
Role of the effect of inhibition of neutral endopeptidase on vascular and neural complications in streptozotocin-induced diabetic rats
Oltman, C. L., Davidson, E. P., Coppey, L. J., Kleinschmidt, T. L., Dake, B. L., & Yorek, M. A. (2010) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2010.10.047 · Cited by 27
Self-citation
Preservation of pressure-induced cutaneous vasodilation by limiting oxidative stress in short-term diabetic mice
Demiot, C., Fromy, B., Saumet, J., & Sigaudo‐Roussel, D. (2005) · Cardiovascular Research · doi:10.1016/j.cardiores.2005.09.005 · Cited by 27
Hyperglycemia-Induced Endothelial Dysfunction
Gerő, D. (2018) · InTech eBooks · doi:10.5772/intechopen.71433 · Cited by 33
Clinical Usefulness of Oral Supplementation with Alpha‐Lipoic Acid, Curcumin Phytosome, and B‐Group Vitamins in Patients with Carpal Tunnel Syndrome Undergoing Surgical Treatment
Pajardi, G., Bortot, P., Ponti, V., & Novelli, C. (2014) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2014/891310 · Cited by 29
NO‐ and non‐NO‐, Non‐Prostanoid‐Dependent Vasodilatation in Rat Sciatic Nerve During Maturation and Developing Experimental Diabetic Neuropathy
Thomsen, K., Rubin, I., & Lauritzen, M. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.023564 · Cited by 26
Effect of Fidarestat and α‐Lipoic Acid on Diabetes‐Induced Epineurial Arteriole Vascular Dysfunction
Yorek, M. A., Coppey, L. J., Gellett, J. S., Davidson, E. P., & Lund, D. D. (2003) · Journal of Diabetes Research · doi:10.1080/15438600490277824 · Cited by 26
Self-citation
Treatment of cardiovascular dysfunction associated with the metabolic syndrome and type 2 diabetes
Oltman, C. L., Kleinschmidt, T. L., Davidson, E. P., Coppey, L. J., Lund, D. D., & Yorek, M. A. (2007) · Vascular Pharmacology · doi:10.1016/j.vph.2007.11.005 · Cited by 25
Self-citation
Polyphenolic Extract ofIchnocarpus FrutescensAttenuates Diabetic Complications in Streptozotocin-Treated Diabetic Rats
Chidambaram, K., & Mandal, S. C. (2008) · Renal Failure · doi:10.1080/08860220701857449 · Cited by 25
A possible link between exercise-training adaptation and dehydroepiandrosterone sulfate- an oldest-old female study
Huang, Y.-J., Chen, M.-T., Fang, C.-L., Lee, W., Yang, S.-C., & Kuo, C. (2006) · International Journal of Medical Sciences · doi:10.7150/ijms.3.141 · Cited by 25
Review of Cellular Changes in the Cochlea Due to Aminoglycoside Antibiotics.
Ding, D., & Salvi, R. (2005) · The Volta Review · Cited by 25
Nitrosative stress in early Type 1 diabetes
Hoeldtke, R. D. (2003) · Clinical Autonomic Research · doi:10.1007/s10286-003-0139-x · Cited by 25
Retracted
Transition metals and polyol pathway in the development of diabetic neuropathy in rats
Nakamura, J., Hamada, Y., Chaya, S., Nakashima, E., Naruse, K., Kato, K., Yasuda, Y., Kamiya, H., Sakakibara, F., Koh, N., et al. (2002) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.319 · Cited by 24
Epigenetic: A missing paradigm in cellular and molecular pathways of sulfur mustard lung: a prospective and comparative study.
İmani, S., Panahi, Y., Salimian, J., Fu, J., & Ghanei, M. (2015) · Europe PMC (PubMed Central) · Cited by 23
Influence of Sex on Cognition and Peripheral Neurovascular Function in Diabetic Mice
Fan, B., Liu, X., Szalad, A., Wang, L., Zhang, R., Chopp, M., & Zhang, Z. G. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00795 · Cited by 25
Treatment for Diabetic Peripheral Neuropathy: What have we Learned from Animal Models?
Yorek, M. A. (2021) · Current Diabetes Reviews · doi:10.2174/1573399817666210504101609 · Cited by 26
Self-citation
Effect of dipyrone and thalidomide alone and in combination on STZ-induced diabetic neuropathic pain
Chauhan, N., Taliyan, R., & Sharma, P. L. (2012) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-011-0724-9 · Cited by 23
Reduction of Oxidative Stress by a New Low-Molecular-Weight Antioxidant Improves Metabolic Alterations in a Nonobese Mouse Diabetes Model
Novelli, M., D’Aleo, V., Lupi, R., Paolini, M., Soleti, A., Marchetti, P., & Masiello, P. (2007) · Pancreas · doi:10.1097/mpa.0b013e318150e4f2 · Cited by 24
Activity and expression of the vanilloid receptor 1 (TRPV1) is altered by long‐term diabetes in epineurial arterioles of the rat sciatic nerve
Davidson, E. P., Coppey, L. J., & Yorek, M. A. (2005) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.599 · Cited by 22
Self-citation
A Therapeutic Target for Microvascular Complications in Diabetes: Endothelium- Derived Hyperpolarizing Factor
Matsumoto, T., Kobayashi, T., & Kamata, K. (2006) · Current Cardiology Reviews · doi:10.2174/157340306778019405 · Cited by 22
Upregulation of caveolin-1 expression is associated with structural modifications of endothelial cells in diabetic lung
Uyy, E., Antohe, F., Ivan, L., Haraba, R., Radu, D. L., & Simionescu, M. (2009) · Microvascular Research · doi:10.1016/j.mvr.2009.11.008 · Cited by 21
Effect of chromium picolinate and melatonin either in single or in a combination in high carbohydrate diet‐fed male Wistar rats
Doddigarla, Z., Ahmad, J., & Parwez, I. (2015) · BioFactors · doi:10.1002/biof.1253 · Cited by 21
12/15-Lipoxygenase inhibition counteracts MAPK phosphorylation in mouse and cell culture models of diabetic peripheral neuropathy
Stavniichuk, R., Obrosov, A. A., Drel, V. R., Nadler, J. L., Obrosova, I. G., & Yorek, M. A. (2013) · Journal of Diabetes Mellitus · doi:10.4236/jdm.2013.33015 · Cited by 20
Self-citation
In Vivo Measurement of Redox Status in Streptozotocin-Induced Diabetic Rat Using Targeted Nitroxyl Probes
Yamada, K., Inoue, D., Matsumoto, S., & Utsumi, H. (2004) · Antioxidants and Redox Signaling · doi:10.1089/152308604773934369 · Cited by 20
Research progress on 2,4-thiazolidinedione and 2-thioxo-4-thiazolidinone analogues as aldose reductase inhibitors
Kharyal, A., Ranjan, S. K., Jaswal, S., Parveen, D., Gupta, G. D., Thareja, S., & Verma, S. K. (2022) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2022.133742 · Cited by 19
Attenuation of experimentally induced diabetic neuropathy in association with reduced oxidative-nitrosative stress by chronic administration of Momordica charantia
Malik, Z. A., Tabassum, N., & Sharma, P. L. (2013) · Advances in Bioscience and Biotechnology · doi:10.4236/abb.2013.43047 · Cited by 19
Contribution of mitochondria to pain in diabetic neuropathy
Hernández-Beltrán, N., Moreno, C. B., & Gutiérrez‐Álvarez, Á. M. (2013) · Endocrinología y Nutrición (English Edition) · doi:10.1016/j.endoen.2013.01.004 · Cited by 19
The role of PPARs in the microvascular dysfunction in diabetes
Vinik, A. I., Parson, H. K., & Ullal, J. (2006) · Vascular Pharmacology · doi:10.1016/j.vph.2005.11.012 · Cited by 19
Effect of Vitamin E on diabetes-induced changes in small intestine and plasma antioxidant capacity in rat
Shirpoor, A., Ilkhanizadeh, B., Saadatian, R., Darvari, B. S., Behtaj, F., Karimipour, M., Pakdel, F. G., & Saboori, E. (2006) · Journal of Physiology and Biochemistry · doi:10.1007/bf03168466 · Cited by 19
Effects of alpha-lipoic acid treatment on serum progranulin levels and inflammatory markers in diabetic neuropathy
Nádró, B., Lőrincz, H., Molnár, Á., Szentpéteri, A., Zöld, E., Seres, I., Páll, D., Paragh, G., Kempler, P., Harangi, M., et al. (2021) · Journal of International Medical Research · doi:10.1177/03000605211012213 · Cited by 19
Current and Future Strategies for the Management of Diabetic Neuropathy
Malik, R. A. (2003) · Treatments in Endocrinology · doi:10.2165/00024677-200302060-00003 · Cited by 18
Vascular and Neural Dysfunctions in Obese Zucker Rats: Effect of AVE7688
Davidson, E. P., Coppey, L. J., Kleinschmidt, T. L., Oltman, C. L., & Yorek, M. A. (2009) · Experimental Diabetes Research · doi:10.1155/2009/912327 · Cited by 17
Self-citation
Na+/H+ exchanger 1 inhibition reverses manifestation of peripheral diabetic neuropathy in type 1 diabetic rats
Lupachyk, S., Watcho, P., Shevalye, H., Vareniuk, І., Obrosov, A. A., Obrosova, I. G., & Yorek, M. A. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00186.2013 · Cited by 17
Self-citation

Authors: Coppey, L. J., Gellett, J. S., Davidson, E. P., Dunlap, J. A., Lund, D. D., & Yorek, M. A.
Affiliations: University of Iowa (US)
ORCID: Yorek, Mark A.
Venue: Diabetes
Publisher: American Diabetes Association
Published: 2001-08-01
Volume: 50
Issue: 8
Pages: 1927-1937
ISSN: 0012-1797 (ISSN-L)
1939-327X
DOI: 10.2337/diabetes.50.8.1927
OpenAlex: W2147294760
Cited by: 300
References: 63
Citations by year: 2026: 4 · 2025: 5 · 2024: 8 · 2023: 6 · 2022: 6 · 2021: 10 · 2020: 6 · 2019: 9 · 2018: 7 · 2017: 16 · 2016: 8 · 2015: 13 · 2014: 10 · 2013: 17 · 2012: 18
FWCI: 8.78
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Diabetes (publishedVersion)
PubMed (publishedVersion)
Funders: American Diabetes Association
U.S. Department of Veterans Affairs (DK-25295)
National Institute of Diabetes and Digestive and Kidney Diseases (DK-25295, DK-58005, P30DK025295)
Topics: Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Aldose Reductase and Taurine
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Biochemical Acid Research Studies
Keywords: streptozotocin-induced diabetes, antioxidant treatment, alpha-lipoic acid, motor nerve conduction velocity, sciatic nerve, superoxide, peroxynitrite, oxidative stress, Na+/K+-ATPase, myo-inositol, sorbitol, diabetic vascular complications, diabetic neuropathy, glutathione, lipid peroxidation
MeSH terms: Sodium-Potassium-Exchanging ATPase, Animals, Antioxidants, Aorta, Arterioles, Diabetes Mellitus, Experimental, Inositol, Thioctic Acid, Male, Motor Neurons, Muscle, Smooth, Vascular, Neural Conduction, Nitrates, Reference Values, Regional Blood Flow, Sciatic Nerve, Sorbitol, Superoxides, Vasodilation, Rats, Sprague-Dawley, Microscopy, Video, Dietary Supplements, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Effect of Antioxidant Treatment of Streptozotocin-Induced Diabetic Rats on Endoneurial Blood Flow, Motor Nerve Conduction Velocity, and Vascular Reactivity of Epineurial Arterioles of the Sciatic Nerve

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks