The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Incidence of childhood type 1 diabetes worldwide. Diabetes Mondiale (DiaMond) Project Group
Open accessAbstract
OBJECTIVE: To investigate and monitor the patterns in incidence of childhood type 1 diabetes worldwide. RESEARCH DESIGN AND METHODS: The incidence of type 1 diabetes (per 100,000 per year) from 1990 to 1994 was determined in children < or =14 years of age from 100 centers in 50 countries. A total of 19,164 cases were diagnosed in study populations totaling 75.1 million children. The annual incidence rates were calculated per 100,000 population. RESULTS: The overall age-adjusted incidence of type 1 diabetes varied from 0.1/100,000 per year in China and Venezuela to 36.8/100,000 per year in Sardinia and 36.5/100,000 per year in Finland. This represents a >350-fold variation in the incidence among the 100 populations worldwide. The global pattern of variation in incidence was evaluated by arbitrarily grouping the populations with a very low (<1/100,000 per year), a low (1-4.99/100,000 per year), an intermediate (5-9.99/100,000 per year), a high (10-19.99/100,000 per year), and a very high (> or =20/100,000 per year) incidence. Of the European populations, 18 of 39 had an intermediate incidence, and the remainder had a high or very high incidence. A very high incidence (> or =20/ 100,000 per year) was found in Sardinia, Finland, Sweden, Norway Portugal, the U.K., Canada, and New Zealand. The lowest incidence (<1/100,000 per year) was found in the populations from China and South America. In most populations, the incidence increased with age and was the highest among children 10-14 years of age. CONCLUSIONS: The range of global variation in the incidence of childhood type 1 diabetes is even larger than previously described. The earlier reported polar-equatorial gradient in the incidence does not seem to be as strong as previously assumed, but the variation seems to follow ethnic and racial distribution in the world population.
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In the citing paper
“Data from large epidemiologic studies worldwide indicate that the incidence of T1D has been increasing by 2–5% worldwide”
From Epidemiology of type 1 diabetes (2010) · cites this paper as [9]
In the citing paper
“The lowest incidence (<1/100,000 per year) was reported in the populations from China and South America and the highest incidence (>20/100,000 per year) was reported in Sardinia, Finland, Sweden, Norway, Portugal, the UK, Canada, and New Zealand.”
From Epidemiology of type 1 diabetes (2010) · cites this paper as [9]
In the citing paper
“The incidence of T1D increased with age in most populations with the highest incidence observed in the 10–14 year olds.”
From Epidemiology of type 1 diabetes (2010) · cites this paper as [9]
In the citing paper
“The US populations included in the DIAMOND study were drawn from the states of Pennsylvania, Alabama, and Illinois reported incidences of 10–20/100,000 per year.”
From Epidemiology of type 1 diabetes (2010) · cites this paper as [9]
In the citing paper
“Within country variation was also reported with rates 3–5 times higher in Sardinia than in continental Italy, with similar variation reported within Portugal, New Zealand, and China.”
From Epidemiology of type 1 diabetes (2010) · cites this paper as [9]
In the citing paper
“A statistically significant male-to-female excess in incidence was reported in 3 centers, but no populations reported a female excess.”
From Epidemiology of type 1 diabetes (2010) · cites this paper as [9]
In the citing paper
“A greater than 350-fold difference in the incidence of T1D among the 100 populations worldwide was reported with age-adjusted incidences ranging from a low of 0.1/100,000 per year in China and Venezuela to a high of 36.5/100,000 in Finland and 36.8/100,000 per year in Sardinia.”
From Epidemiology of type 1 diabetes (2010) · cites this paper as [9]
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Citations
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Self-citation
Research works printed but not linked: 2
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Cited by
Sorted by citations
Atkinson, M. A., Eisenbarth, G. S., & Michels, A. W. (2014) · The Lancet · doi:10.1016/s0140-6736(13)60591-7 · Cited by 2,931
Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary
Rydén, L., Standl, E., Bartnik, M., den Berghe, G. V., Betteridge, J. D., de Boer, M., Cosentino, F., Jönsson, B., Laakso, M., Malmberg, K., et al. (2007) · European Heart Journal · doi:10.1093/eurheartj/ehl260 · Cited by 1,644
Self-citationIncidence trends of type 1 and type 2 diabetes among youths, 2002–2012
Mayer-Davis, E. J., Lawrence, J. M., Dabelea, D., Divers, J., Isom, S., Dolan, L., Imperatore, G., Linder, B., Marcovina, S., Pettitt, D. J., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1610187 · Cited by 1,476
Epidemiology of type 1 diabetes
Maahs, D. M., West, N. A., Lawrence, J. M., & Mayer-Davis, E. J. (2010) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2010.05.011 · Cited by 1,092
Incidence and trends of childhood type 1 diabetes worldwide 1990–1999
The DIAMOND Project Group (2006) · Diabetic Medicine · doi:10.1111/j.1464-5491.2006.01925.x · Cited by 1,085
Metadata
- Authors
- Karvonen, M., Viik-Kajander, M., Moltchanova, E., Libman, I., LaPorte, R., & Tuomilehto, J.
- Affiliations
- Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland. marjatta.karvonen@ktl.fi
- University of Pittsburgh (US)
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2000-10-01
- Volume
- 23
- Issue
- 10
- Pages
- 1516-1526
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- OpenAlex
- W2115209313
- Cited by
- 1,072
- References
- 22
- Citations by year
- 2026: 11 · 2025: 16 · 2024: 24 · 2023: 24 · 2022: 20 · 2021: 36 · 2020: 33 · 2019: 38 · 2018: 37 · 2017: 41 · 2016: 48 · 2015: 52 · 2014: 66 · 2013: 54 · 2012: 65
- FWCI
- 15.86
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Diabetes Care (publishedVersion)
- PubMed (publishedVersion)
- Funders
- World Health Organization
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- type 1 diabetes, pediatric diabetes, incidence, global variation, racial and ethnic differences, age distribution, Sardinia, Finland, cross-national comparison
- MeSH terms
- Adolescent, Child, Child, Preschool, Diabetes Mellitus, Type 1, Female, Humans, Infant, Male, Risk Factors, Sex Factors, Global Health, World Health Organization, Incidence, Age Distribution
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