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Hyaluronan and synovial joint: function, distribution and healing
Open accessAbstract
Synovial fluid is a viscous solution found in the cavities of synovial joints. The principal role of synovial fluid is to reduce friction between the articular cartilages of synovial joints during movement. The presence of high molar mass hyaluronan (HA) in this fluid gives it the required viscosity for its function as lubricant solution. Inflammation oxidation stress enhances normal degradation of hyaluronan causing several diseases related to joints. This review describes hyaluronan properties and distribution, applications and its function in synovial joints, with short review for using thiol compounds as antioxidants preventing HA degradations under inflammation conditions.
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Cites
Hyaluronic acid (hyaluronan): A review
Necas, J., Bartosikova, L., Brauner, P., & Kolar, J. (2008) · Veterinární medicína · doi:10.17221/1930-vetmed · Cited by 998
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Choi, K. Y., Han, H. S., Lee, E. S., Shin, J. M., Almquist, B. D., Lee, D. S., & Park, J. H. (2019) · Advanced Materials · doi:10.1002/adma.201803549 · Cited by 319
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Metadata
- Authors
- Tamer, T. M.
- Venue
- Interdisciplinary Toxicology
- Publisher
- Walter de Gruyter GmbH
- Published
- 2013-09-01
- Volume
- 6
- Issue
- 3
- Pages
- 111-125
- ISSN
- 1337-6853 (ISSN-L)
- 1337-9569
- OpenAlex
- W1975662862
- Cited by
- 317
- References
- 1
- FWCI
- 2.75
- Type
- journal article
- Language
- en
- Open access
- diamond
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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