The DOI matches its Crossref record; 103 of the 103 references it cites were found in a registry or an index.
Protein-mediated Enamel Mineralization
Open accessAbstract
Enamel is a hard nanocomposite bioceramic with significant resilience that protects the mammalian tooth from external physical and chemical damages. The remarkable mechanical properties of enamel are associated with its hierarchical structural organization and its thorough connection with underlying dentin. This dynamic mineralizing system offers scientists a wealth of information that allows the study of basic principels of organic matrix-mediated biomineralization and can potentially be utilized in the fields of material science and engineering for development and design of biomimetic materials. This chapter will provide a brief overview of enamel hierarchical structure and properties and the process and stages of amelogenesis. Particular emphasis is given to current knowledge of extracellular matrix protein and proteinases, and the structural chemistry of the matrix components and their putative functions. The chapter will conclude by discussing the potential of enamel for regrowth.
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Citations
Cites
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Self-citationMechanical properties of human dental enamel on the nanometre scale
Habelitz, S., Marshall, S. J., Marshall, G. W., & Balooch, M. (2001) · Archives of Oral Biology · doi:10.1016/s0003-9969(00)00089-3 · Cited by 554
Amelogenin-deficient Mice Display an Amelogenesis Imperfecta Phenotype
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Cited by
Dental Enamel Formation and Implications for Oral Health and Disease
Lacruz, R. S., Habelitz, S., Wright, J. T., & Paine, M. L. (2017) · Physiological Reviews · doi:10.1152/physrev.00030.2016 · Cited by 599
State of the Art Enamel Remineralization Systems: The Next Frontier in Caries Management
Philip, N. (2019) · Caries Research · doi:10.1159/000493031 · Cited by 341
Quantitative affinity parameters of synthetic hydroxyapatite and enamel surfaces in vitro
Fabritius-Vilpoux, K., Enax, J., Herbig, M., Raabe, D., & Fabritius, H.-O. (2019) · Bioinspired, Biomimetic and Nanobiomaterials · doi:10.1680/jbibn.18.00035 · Cited by 53
Biomimetic supramolecular protein matrix restores structure and properties of human dental enamel
Hasan, A., Chuvilin, A., Van Teijlingen, A., Rouco, H., Parmenter, C., Venturi, F., Fay, M., Greco, G., Pugno, N. M., Ruben, J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-64982-y · Cited by 15
Metadata
- Authors
- Moradian-Oldak, J.
- Venue
- Frontiers in Bioscience
- Publisher
- IMR Press
- Published
- 2012
- Volume
- 17
- Issue
- 7
- Pages
- 1996
- ISSN
- 1093-4715 (ISSN-L)
- 1093-9946
- DOI
- 10.2741/4034
- OpenAlex
- W1979876637
- Cited by
- 321
- References
- 103
- FWCI
- 9.80
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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