Calcium signalling in chondrogenesis implications for cartilage repair

Multilineage potential of adult human mesenchymal stem cells

Pittenger, M. F., Mackay, A. M., Beck, S. C., Jaiswal, R. K., Douglas, R., Mosca, J. D., Moorman, M. A., Simonetti, D. W., Craig, S., & Marshak, D. R. (1999) · Science · doi:10.1126/science.284.5411.143 · Cited by 21,052 · see citing works

Calcium signalling: dynamics, homeostasis and remodelling

Berridge, M., Bootman, M., & Roderick, H. (2003) · Nature reviews. Molecular cell biology · doi:10.1038/nrm1155 · Cited by 5,747 · see citing works

Treatment of Deep Cartilage Defects in the Knee with Autologous Chondrocyte Transplantation

Brittberg, M., Lindahl, A. H., Nilsson, A., Ohlsson, C., Isaksson, O. G. P., & Peterson, L. (1994) · New England Journal of Medicine · doi:10.1056/nejm199410063311401 · Cited by 5,510 · see citing works

Receptors for Purines and Pyrimidines

Burnstock, G., & Verkhratsky, A. (2012) · Springer eBooks · doi:10.1007/978-3-642-28863-0_5 · Cited by 3,973 · see citing works

Transcriptional regulation by calcium, calcineurin, and NFAT

Hogan, P. G., Chen, L., Nardone, J., & Rao, A. (2003) · Genes & Development · doi:10.1101/gad.1102703 · Cited by 1,991 · see citing works

Calcium oscillations increase the efficiency and specificity of gene expression

Dolmetsch, R. E., Xu, K., & Lewis, R. S. (1998) · Nature · doi:10.1038/31960 · Cited by 1,896 · see citing works

The control of chondrogenesis

Goldring, M. B., Tsuchimochi, K., & Ijiri, K. (2005) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20652 · Cited by 1,062 · see citing works

The surface of articular cartilage contains a progenitor cell population

Dowthwaite, G. P., Bishop, J. C., Redman, S. N., Khan, I. M., Rooney, P., Evans, D. J. R., Haughton, L., Bayram, Z., Boyer, S., Thomson, B., et al. (2004) · Journal of Cell Science · doi:10.1242/jcs.00912 · Cited by 916 · see citing works

Adult mesenchymal stem cells and cell-based tissue engineering.

Tuan, R. S., Boland, G. M., & Tuli, R. (2003) · Arthritis Research · doi:10.1186/ar614 · Cited by 780 · see citing works

TRP channels: An overview

Pedersen, S. F., Owsianik, G., & Nilius, B. (2005) · Cell Calcium · doi:10.1016/j.ceca.2005.06.028 · Cited by 779 · see citing works

Stage-related capacity for limb chondrogenesis in cell culture

Ahrens, P. B., Solursh, M., & Reiter, R. S. (1977) · Developmental Biology · doi:10.1016/0012-1606(77)90110-5 · Cited by 613 · see citing works

Structure and biology of cartilage and bone matrix noncollagenous macromolecules

Heinegård, D. K., & Oldberg, Å. (1989) · The FASEB Journal · doi:10.1096/fasebj.3.9.2663581 · Cited by 567 · see citing works

Molecular basis of NMDA receptor functional diversity

Paoletti, P. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07628.x · Cited by 446 · see citing works

The Role of Transient Receptor Potential Cation Channels in Ca2+ SignalingPreprint

Gees, M., Colsoul, B., & Nilius, B. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a003962 · Cited by 437 · see citing works

Modulation of the Ras/Raf/MEK/ERK pathway by Ca2+, and Calmodulin

Agell, N., Bachs, O., Rocamora, N., & Villalonga, P. (2002) · Cellular Signalling · doi:10.1016/s0898-6568(02)00007-4 · Cited by 398 · see citing works

The structure and function of cartilage proteoglycans

Roughley, P. (2006) · European Cells and Materials · doi:10.22203/ecm.v012a11 · Cited by 352 · see citing works

Glutamate signalling in non-neuronal tissues

Skerry, T. M., & Genever, P. G. (2001) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(00)01642-4 · Cited by 308 · see citing works

Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes

Phan, M. N., Leddy, H. A., Votta, B. J., Kumar, S., Levy, D. S., Lipshutz, D. B., Lee, S. H., Liedtke, W., & Guilak, F. (2009) · Arthritis & Rheumatism · doi:10.1002/art.24799 · Cited by 308 · see citing works

Regulation of matrix synthesis rates by the ionic and osmotic environment of articular chondrocytes

Urban, J., Hall, A. C., & Gehl, K. A. (1993) · Journal of Cellular Physiology · doi:10.1002/jcp.1041540208 · Cited by 294 · see citing works

Contact pressures in the human hip joint

Afoke, N., Byers, P., & Hutton, W. (1987) · The Journal of Bone and Joint Surgery. British volume · doi:10.1302/0301-620x.69b4.3611154 · Cited by 268 · see citing works

Hydrostatic Pressure in Articular Cartilage Tissue Engineering: From Chondrocytes to Tissue Regeneration

Elder, B. D., & Athanasiou, K. A. (2009) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2008.0435 · Cited by 267 · see citing works

Changes in the patterns of collagens and fibronectin during limb-bud chondrogenesis

Dessau, W., von der Mark, H., von der Mark, K., & Fischer, S. (1980) · Development · doi:10.1242/dev.57.1.51 · Cited by 265 · see citing works

The structural architecture of adult mammalian articular cartilage evolves by a synchronized process of tissue resorption and neoformation during postnatal development

Hunziker, E. B., Kapfinger, E., & Geiss, J. (2006) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2006.09.010 · Cited by 259 · see citing works

NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation

Tomida, T., Hirose, K., Takizawa, A., Shibasaki, F., & Iino, M. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg381 · Cited by 255 · see citing works

Functional Gene Screening System Identified TRPV4 as a Regulator of Chondrogenic Differentiation

Muramatsu, S., Wakabayashi, M., Ohno, T., Amano, K., Ooishi, R., Sugahara, T., Shiojiri, S., Tashiro, K., Suzuki, Y., Nishimura, R., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m706158200 · Cited by 225 · see citing works

Mechanical stimuli differentially control stem cell behavior: morphology, proliferation, and differentiation

Maul, T. M., Chew, D. W., Nieponice, A., & Vorp, D. A. (2011) · Biomechanics and Modeling in Mechanobiology · doi:10.1007/s10237-010-0285-8 · Cited by 224 · see citing works

Ca2+ Oscillations in Non-Excitable Cells

Fewtrell, C. (1993) · Annual Review of Physiology · doi:10.1146/annurev.ph.55.030193.002235 · Cited by 223 · see citing works

Mesenchymal stem cells in regenerative medicine: Opportunities and challenges for articular cartilage and intervertebral disc tissue engineering

Richardson, S. M., Hoyland, J. A., Mobasheri, R., Buhrmann, C., Shakibaei, M., & Mobasheri, A. (2009) · Journal of Cellular Physiology · doi:10.1002/jcp.21915 · Cited by 217 · see citing works

Opposing Role of Mitogen-activated Protein Kinase Subtypes, Erk-1/2 and p38, in the Regulation of Chondrogenesis of Mesenchymes

Oh, C., Chang, S.-H., Yoon, Y., Lee, S., Lee, Y., Kang, S.-S., & Chun, J.-S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.8.5613 · Cited by 217 · see citing works

The cartilage collagens: a review of their structure, organization, and role in the pathogenesis of experimental arthritis in animals and in human rheumatic disease

Cremer, M. A., Rosloniec, E. F., & Kang, A. H. (1998) · Journal of Molecular Medicine · doi:10.1007/s001090050217 · Cited by 204 · see citing works

I ARC, a Novel Arachidonate-regulated, Noncapacitative Ca2+ Entry Channel

Mignen, O., & Shuttleworth, T. J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.13.9114 · Cited by 203 · see citing works

MAP kinase and calcium signaling mediate fluid flow-induced human mesenchymal stem cell proliferation

Riddle, R. C., Taylor, A. F., Genetos, D. C., & Donahue, H. J. (2005) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00082.2005 · Cited by 194 · see citing works

The role of N ‐methyl‐ D ‐asparate receptors in neurogenesis

Nácher, J., & McEwen, B. S. (2006) · Hippocampus · doi:10.1002/hipo.20160 · Cited by 189 · see citing works

Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: Age‐ and sex‐dependent progression of osteoarthritis in Trpv4 ‐deficient mice

Clark, A. L., Votta, B. J., Kumar, S., Liedtke, W., & Guilak, F. (2010) · Arthritis & Rheumatism · doi:10.1002/art.27624 · Cited by 188 · see citing works

N-CAM and N-Cadherin Expression during in Vitro Chondrogenesis

Tavella, S., Raffo, P., Tacchetti, C., Cancedda, R., & Castagnola, P. (1994) · Experimental Cell Research · doi:10.1006/excr.1994.1352 · Cited by 188 · see citing works

Characterization of Ca2+ signaling pathways in human mesenchymal stem cells

Kawano, S., Shoji, S., Ichinose, S., Yamagata, K., Tagami, M., & Hiraoka, M. (2002) · Cell Calcium · doi:10.1016/s0143416002001240 · Cited by 175 · see citing works

Physical Stimulation of Chondrogenic Cells In Vitro: A Review

Grad, S., Eglin, D., Alini, M., & Stoddart, M. J. (2011) · Clinical Orthopaedics and Related Research · doi:10.1007/s11999-011-1819-9 · Cited by 174 · see citing works

MAP kinases in chondrocyte differentiation

Stanton, L., Underhill, T. M., & Beier, F. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00321-x · Cited by 169 · see citing works

ATP autocrine/paracrine signaling induces calcium oscillations and NFAT activation in human mesenchymal stem cells

Kawano, S., Otsu, K., Kuruma, A., Shoji, S., Yanagida, E., Muto, Y., Yoshikawa, F., Hirayama, Y., Mikoshiba, K., & Furuichi, T. (2006) · Cell Calcium · doi:10.1016/j.ceca.2005.11.008 · Cited by 159 · see citing works

The role of TGFβs and Sox9 during limb chondrogenesis

Kawakami, Y., Rodríguez‐León, J., & Belmonte, J. C. I. (2006) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2006.10.007 · Cited by 156 · see citing works

Regenerative medicine through mesenchymal stem cells for bone and cartilage repair.

Noël, D., Djouad, F., & Jorgense, C. (2002) · PubMed · Cited by 155 · see citing works

STIM1- and Orai1-dependent Store-operated Calcium Entry Regulates Human Myoblast Differentiation

Darbellay, B., Arnaudeau, S., König, S., Jousset, H., Bader, C. R., Demaurex, N., & Bernheim, L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m806726200 · Cited by 152 · see citing works

Developmental control of chondrogenesis and osteogenesis

Cancedda, R., Castagnola, P., Cancedda, F. D., Dozin, B., & Quarto, R. (2000) · The International Journal of Developmental Biology · doi:10.1387/ijdb.11061435 · Cited by 147 · see citing works

Morphogenetic and Regulatory Mechanisms During Developmental Chondrogenesis: New Paradigms for Cartilage Tissue Engineering

Quintana, L., Nieden, N. I. Z., & Semino, C. E. (2008) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2008.0329 · Cited by 145 · see citing works

Expression of B7 costimulatory molecules by salivary gland epithelial cells in patients with Sj�gren's syndrome

Manoussakis, M. N., Dimitriou, I. D., Kapsogeorgou, E. K., Xanthou, G., Paikos, S., Polihronis, M., & Moutsopoulos, H. Μ. (1999) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199902)42:2 · Cited by 134 · see citing works

The molecular architecture of the arachidonate‐regulated Ca2+‐selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits

Mignen, O., Thompson, J. L., & Shuttleworth, T. J. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2009.174193 · Cited by 129 · see citing works

Signal transduction in electrically stimulated articular chondrocytes involves translocation of extracellular calcium through voltage-gated channels

Xu, J., Wang, W., Clark, C. C. A., & Brighton, C. T. (2008) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2008.07.001 · Cited by 128 · see citing works

Stem Cells and Cartilage Development: Complexities of a Simple Tissue

Hollander, A. P., Dickinson, S. C., & Kafienah, W. (2010) · Stem Cells · doi:10.1002/stem.534 · Cited by 127 · see citing works

Purinergic signaling in embryonic and stem cell development

Burnstock, G., & Ulrich, H. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-010-0614-1 · Cited by 125 · see citing works

Mechanical Influences on Morphogenesis of the Knee Joint Revealed through Morphological, Molecular and Computational Analysis of Immobilised Embryos

Roddy, K. A., Prendergast, P. J., & Murphy, P. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017526 · Cited by 124 · see citing works

A SOX9 Defect of Calmodulin-dependent Nuclear Import in Campomelic Dysplasia/Autosomal Sex Reversal

Argentaro, A., Sim, H., Kelly, S., Preiss, S., Clayton, A. H. A., Jans, D. A., & Harley, V. R. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m302078200 · Cited by 119 · see citing works

The emerging chondrocyte channelome

Barrett‐Jolley, R. (2010) · Frontiers in Physiology · doi:10.3389/fphys.2010.00135 · Cited by 118 · see citing works

The STIM/Orai coupling machinery

Frischauf, I., Schindl, R., Derler, I., Bergsmann, J., Fahrner, M., & Romanin, C. (2008) · Channels · doi:10.4161/chan.2.4.6705 · Cited by 117 · see citing works

Chondrogenic Differentiation of Mesenchymal Stem Cells and Its Clinical Applications

Lee, J. W., Kim, Y. H., Kim, S. H., Han, S. H., & Hahn, S. B. (2004) · Yonsei Medical Journal · doi:10.3349/ymj.2004.45.suppl.41 · Cited by 116 · see citing works

Recent developments in non-excitable cell calcium entry

Elliott, A. C. (2001) · Cell Calcium · doi:10.1054/ceca.2001.0215 · Cited by 110 · see citing works

Ca2+ oscillations regulated by Na+–Ca2+ exchanger and plasma membrane Ca2+ pump induce fluctuations of membrane currents and potentials in human mesenchymal stem cells

Kawano, S., Otsu, K., Shoji, S., Yamagata, K., & Hiraoka, M. (2003) · Cell Calcium · doi:10.1016/s0143-4160(03)00069-1 · Cited by 107 · see citing works

Arachidonic acid, ARC channels, and Orai proteins

Shuttleworth, T. J. (2009) · Cell Calcium · doi:10.1016/j.ceca.2009.02.001 · Cited by 105 · see citing works

Chondrogenesis of limb bud mesenchyme in vitro: Stimulation by cations

Antonio, J. D. S., & Tuan, R. S. (1986) · Developmental Biology · doi:10.1016/0012-1606(86)90252-6 · Cited by 101 · see citing works

Store-Operated Ca 2+ Entry Is Expressed in Human Endothelial Progenitor Cells

Sánchez-Hernández, Y., Laforenza, U., Bonetti, E., Fontana, J. M., Dragoni, S., Russo, M. A., Avelino-Cruz, J. E., Schinelli, S., Testa, D., Guerra, G., et al. (2010) · Stem Cells and Development · doi:10.1089/scd.2010.0047 · Cited by 101 · see citing works

Calcium Ion as a Second Messenger With Special Reference to Excitation-Contraction Coupling

Endo, M. (2006) · Journal of Pharmacological Sciences · doi:10.1254/jphs.cpj06004x · Cited by 100 · see citing works

Chondrogenesis, joint formation, and articular cartilage regeneration

Onyekwelu, I., Goldring, M. B., & Hidaka, C. (2009) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22149 · Cited by 99 · see citing works

Modulation of cellular differentiation by N ‐methyl‐ d ‐aspartate receptors in osteoblasts

Hinoi, E., Fujimori, S., & Yoneda, Y. (2003) · The FASEB Journal · doi:10.1096/fj.02-0820fje · Cited by 99 · see citing works

The role of the membrane potential in chondrocyte volume regulation

Lewis, R., Asplin, K. E., Bruce, G., Dart, C., Mobasheri, A., & Barrett‐Jolley, R. (2011) · Journal of Cellular Physiology · doi:10.1002/jcp.22646 · Cited by 92 · see citing works

Ca2+ signaling, genes and the cell cycle

Machaca, K. (2010) · Cell Calcium · doi:10.1016/j.ceca.2010.10.003 · Cited by 92 · see citing works

Calcium signaling leads to mitochondrial depolarization in impact‐induced chondrocyte death in equine articular cartilage explants

Huser, C. A. M., & Davies, M. (2007) · Arthritis & Rheumatism · doi:10.1002/art.22717 · Cited by 91 · see citing works

ATP in the mechanotransduction pathway of normal human chondrocytes

Millward-Sadler, S. J., Wright, M. O., Flatman, P. W., & Salter, D. M. (2004) · Biorheology · doi:10.1177/0006355x2004041003004022 · Cited by 90 · see citing works

Electrophysiological Properties of Pluripotent Human and Mouse Embryonic Stem Cells

Wang, K., Xue, T., Tsang, S. Y., van Huizen, R., Wong, C. W., Lai, K. W.-H., Ye, Z., Cheng, L., Au, K. W., Zhang, J., et al. (2005) · Stem Cells · doi:10.1634/stemcells.2004-0299 · Cited by 86 · see citing works

ARC Channels: A Novel Pathway for Receptor-Activated Calcium Entry

Shuttleworth, T. J., Thompson, J. L., & Mignen, O. (2004) · Physiology · doi:10.1152/physiol.00018.2004 · Cited by 85 · see citing works

Ion Channels in Mesenchymal Stem Cells from Rat Bone Marrow

Li, G.-R., Deng, X., Sun, H., Chung, S. S., Tse, H., & Lau, C. (2006) · Stem Cells · doi:10.1634/stemcells.2005-0307 · Cited by 85 · see citing works

Expression of voltage sensitive calcium channel (VSCC) L‐type Cav1.2 (α1C) and T‐type Cav3.2 (α1H) subunits during mouse bone development

Shao, Y., Alicknavitch, M., & Farach‐Carson, M. C. (2005) · Developmental Dynamics · doi:10.1002/dvdy.20517 · Cited by 85 · see citing works

Cyclic loading opens hemichannels to release ATP as part of a chondrocyte mechanotransduction pathway

Garcia, M. B., & Knight, M. M. (2009) · Journal of Orthopaedic Research® · doi:10.1002/jor.21025 · Cited by 83 · see citing works

Functional expression of Ca2+ signaling pathways in mouse embryonic stem cells

Yanagida, E., Shoji, S., Hirayama, Y., Yoshikawa, F., Otsu, K., Uematsu, H., Hiraoka, M., Furuichi, T., & Kawano, S. (2004) · Cell Calcium · doi:10.1016/j.ceca.2004.01.022 · Cited by 79 · see citing works

Lubricin: a novel potential biotherapeutic approaches for the treatment of osteoarthritis

Bao, J., Chen, W., & Wu, L. (2010) · Molecular Biology Reports · doi:10.1007/s11033-010-9949-9 · Cited by 76 · see citing works

Beta1-integrins co-localize with Na, K-ATPase, epithelial sodium channels (ENaC) and voltage activated calcium channels (VACC) in mechanoreceptor complexes of mouse limb-bud chondrocytes.

Shakibaei, M., & Mobasheri, A. (2003) · PubMed · doi:10.14670/hh-18.343 · Cited by 76 · see citing works

Expression of ion channels of the TRP family in articular chondrocytes from osteoarthritic patients: changes between native and in vitro propagated chondrocytes

Gavénis, K., Schumacher, C., Schneider, U., Eisfeld, J., Mollenhauer, J., & Schmidt-Rohlfing, B. (2008) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-008-9927-x · Cited by 73 · see citing works

Mechanically induced calcium signaling in chondrocytes in situ

Han, S., Wouters, W. A. J., Clark, A. L., & Herzog, W. (2011) · Journal of Orthopaedic Research® · doi:10.1002/jor.21536 · Cited by 73 · see citing works

Subculture of Chondrocytes on a Collagen Type I-Coated Substrate with Suppressed Cellular Dedifferentiation

Kino‐oka, M., Yashiki, S., Ota, Y., 虫明, 裕., Sugawara, K., Yamamoto, T., Takezawa, T., & Taya, M. (2005) · Tissue Engineering · doi:10.1089/ten.2005.11.597 · Cited by 72 · see citing works

NMDA receptor expression and roles in human articular chondrocyte mechanotransduction.

Salter, D. M., Wright, M. O., & Millward-Sadler, S. J. (2004) · PubMed · Cited by 70 · see citing works

In vitro mesenchymal stem cell differentiation after mechanical stimulation

Sarraf, C., Otto, W. R., & Eastwood, M. (2010) · Cell Proliferation · doi:10.1111/j.1365-2184.2010.00740.x · Cited by 66 · see citing works

Spontaneous oscillation and mechanically induced calcium waves in chondrocytes

Kono, T., Nishikori, T., Kataoka, H. C., Uchio, Y., Ochi, M., & Enomoto, K. (2005) · Cell Biochemistry and Function · doi:10.1002/cbf.1304 · Cited by 65 · see citing works

Transient Receptor Potential Melastatin Type 7 Channel Is Critical for the Survival of Bone Marrow Derived Mesenchymal Stem Cells

Cheng, H., Feng, J., Figueiredo, M. L., Zhang, H., Nelson, P. L., Marigo, V., & Beck, A. (2009) · Stem Cells and Development · doi:10.1089/scd.2009.0262 · Cited by 61 · see citing works

Activation of chondrocytes calcium signalling by dynamic compression is independent of number of cycles

Pingguan‐Murphy, B., Lee, D. A., Bader, D. L., & Knight, M. M. (2005) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2005.09.015 · Cited by 58 · see citing works

Physicochemical Control of Adult Stem Cell Differentiation: Shedding Light on Potential Molecular Mechanisms

Titushkin, I. A., Sun, S., Shin, J. H., & Cho, M. (2010) · BioMed Research International · doi:10.1155/2010/743476 · Cited by 57 · see citing works

Molecular and Functional Expression of Voltage-Operated Calcium Channels During Osteogenic Differentiation of Human Mesenchymal Stem Cells

Zahanich, I., Graf, E., Heubach, J. F., Hempel, U., Boxberger, S., & Ravens, U. (2005) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.050521 · Cited by 56 · see citing works

TRPV Channels’ Role in Osmotransduction and Mechanotransduction

Liedtke, W. (2007) · Handbook of experimental pharmacology · doi:10.1007/978-3-540-34891-7_28 · Cited by 56 · see citing works

Cytosolic free Ca2+ concentration exhibits a characteristic temporal pattern during in vitro cartilage differentiation: A possible regulatory role of calcineurin in Ca-signalling of chondrogenic cells

Matta, C., Fodor, J., Szíjgyártó, Z., Juhász, T., Gergely, P., Csernoch, L. J., & Zákány, R. (2008) · Cell Calcium · doi:10.1016/j.ceca.2007.12.010 · Cited by 55 · see citing works

NMDA receptor expression and activity in osteoarthritic human articular chondrocytes

Ramage, L., Martel, M., Hardingham, G. E., & Salter, D. M. (2008) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2008.04.023 · Cited by 54 · see citing works

Dynamic patterns of mechanical stimulation co-localise with growth and cell proliferation during morphogenesis in the avian embryonic knee joint

Roddy, K. A., Kelly, G. M., van Es, M. H., Murphy, P., & Prendergast, P. J. (2010) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2010.08.039 · Cited by 54 · see citing works

Up-regulated P21CIP1 expression is part of the regulation quantitatively controlling serum deprivation-induced apoptosis

Duttaroy, A., Qian, J.-F., Smith, J. S., & Wang, E. (1997) · Journal of Cellular Biochemistry · doi:10.1002/(sici)1097-4644(19970301)64:3 · Cited by 51 · see citing works

Mechanisms involved in the increase in intracellular calcium following hypotonic shock in bovine articular chondrocytes.

Sánchez, J. C., Danks, T. A., & Wilkins, R. J. (2003) · PubMed · Cited by 51 · see citing works

Protein Kinase A Regulates Chondrogenesis of Mesenchymal Cells at the Post-Precartilage Condensation Stage via Protein Kinase C-α Signaling

Yoon, Y., Oh, C., Kang, S., & Chun, J. S. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.11.2197 · Cited by 49 · see citing works

Protein Phosphatase 2A Is Involved in the Regulation of Protein Kinase A Signaling Pathway during in Vitro Chondrogenesis

Zákány, R., Szücs, K., Bakó, É., Felszeghy, S., Czifra, G., Bı́ró, T., Módis, L., & Gergely, P. (2002) · Experimental Cell Research · doi:10.1006/excr.2002.5487 · Cited by 48 · see citing works

Expression of Protein Kinase C Isozymes That Are Required for Chondrogenesis of Chick Limb Bud Mesenchymal Cells

Choi, B., Chun, J. S., Lee, Y. S., Sonn, J. K., & Kang, S. S. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.2724 · Cited by 48 · see citing works

Developmental Regulation of Human Embryonic Stem Cell-Derived Neurons by Calcium Entry via Transient Receptor Potential Channels

Weick, J. P., Johnson, M., & Zhang, S. (2009) · Stem Cells · doi:10.1002/stem.212 · Cited by 46 · see citing works

Current perspectives on NMDA-type glutamate signalling in bone

Spencer, G. J., McGrath, C. J., & Genever, P. G. (2006) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2006.11.002 · Cited by 45 · see citing works

Calcium regulates cyclic compression-induced early changes in chondrocytes during in vitro cartilage tissue formation

Raizman, I., Croos, J. N. A. D., Pilliar, R. M., & Kandel, R. A. (2010) · Cell Calcium · doi:10.1016/j.ceca.2010.09.006 · Cited by 44 · see citing works

Hydrogen peroxide inhibits formation of cartilage in chicken micromass cultures and decreases the activity of calcineurin: implication of ERK1/2 and Sox9 pathways

Zákány, R., Szíjgyártó, Z., Matta, C., Juhász, T., Csoŕtos, C., Szücs, K., Czifra, G., Bı́ró, T., Módis, L., & Gergely, P. (2005) · Experimental Cell Research · doi:10.1016/j.yexcr.2004.12.016 · Cited by 44 · see citing works

Switch of Voltage-Gated K+ Channel Expression in the Plasma Membrane of Chondrogenic Cells Affects Cytosolic Ca2+-Oscillations and Cartilage Formation

Varga, Z., Juhász, T., Matta, C., Fodor, J., Katona, É., Bartók, Á., Oláh, T., Sebe, A., Csernoch, L. J., Panyi, G., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027957 · Cited by 42 · see citing works

Functional Characterization of Calcium-Signaling Pathways of Human Skin-Derived Mesenchymal Stem Cells

Orciani, M., Mariggiò, M. A., Morabito, C., Benedetto, G. D., & Primio, R. D. (2009) · Skin Pharmacology and Physiology · doi:10.1159/000270383 · Cited by 41 · see citing works

Pharmacological characterization of P2X1 and P2X3 purinergic receptors in bovine chondrocytes

Varani, K., Mattei, M. D., Vincenzi, F., Tosi, A., Gessi, S., Merighi, S., Pellati, A., Masieri, F. F., Ongaro, A., & Borea, P. A. (2008) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2008.03.016 · Cited by 39 · see citing works

Extracellular ATP modulates [Ca2+]i in retinoic acid-treated embryonic chondrocytes

Hung, C. T., Allen, F. D., Mansfield, K. D., & Shapiro, I. M. (1997) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1997.272.5.c1611 · Cited by 39 · see citing works

Extracellular nucleotides act through P2U purinoceptors to elevate [Ca2+]i and enhance basic fibroblast growth factor-induced proliferation in sheep chondrocytes

Kaplan, A. D., Kilkenny, D. M., Hill, D. J., & Dixon, S. J. (1996) · Endocrinology · doi:10.1210/endo.137.11.8895344 · Cited by 38 · see citing works

Arachidonate metabolism during chondrogenesisin vitro

Chepenik, K. P., Ho, W. C., Waite, B. M., & Parker, C. L. (1984) · Calcified Tissue International · doi:10.1007/bf02405314 · Cited by 38 · see citing works

Chondrogenic potential of chick embryonic calvaria: I. Low calcium permits cartilage differentiation

Jacenko, O., & Tuan, R. S. (1995) · Developmental Dynamics · doi:10.1002/aja.1002020103 · Cited by 37 · see citing works

Chondrogenesis induced by actin cytoskeleton disruption is regulated via protein kinase C‐dependent p38 mitogen‐activated protein kinase signaling

Lim, Y., Kang, S., An, W. G., Lee, Y., Chun, J., & Sonn, J. K. (2002) · Journal of Cellular Biochemistry · doi:10.1002/jcb.10389 · Cited by 36 · see citing works

Ca2+ oscillations and intercellular Ca2+ waves in ATP-stimulated articular chondrocytes

DAndrea, R., & Vittur, F. (1996) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650110711 · Cited by 35 · see citing works

The surgical treatment of knee injuries in skiers

Steadman, J. R., & Sterett, W. I. (1995) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199503000-00007 · Cited by 35 · see citing works

Ionotropic purinergic receptor P2X4 is involved in the regulation of chondrogenesis in chicken micromass cell cultures

Fodor, J., Matta, C., Juhász, T., Oláh, T., Gönczi, M., Szíjgyártó, Z., Gergely, P., Csernoch, L. J., & Zákány, R. (2009) · Cell Calcium · doi:10.1016/j.ceca.2009.02.004 · Cited by 32 · see citing works

Musculoskeletal mechanobiology: Interpretation by external force and engineered substratum

McCullen, S. D., Haslauer, C. M., & Loboa, E. G. (2009) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2009.09.017 · Cited by 31 · see citing works

Calcium signaling in pluripotent stem cells

Apáti, Á., Pászty, K., Erdei, Z., Szebényi, K., Homolya, L., & Sarkadi, B. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.08.038 · Cited by 31 · see citing works

The intracellular Ca2+-pump inhibitors thapsigargin and cyclopiazonic acid induce stress proteins in mammalian chondrocytes

Cheng, T. C., & Benton, H. P. (1994) · Biochemical Journal · doi:10.1042/bj3010563 · Cited by 30 · see citing works

Ca(2+) Oscillations and Its Transporters in Mesenchymal Stem Cells

Ye, B. (2010) · Physiological Research · doi:10.33549/physiolres.931734 · Cited by 28 · see citing works

Spatial and Temporal Ca2+ Signaling in Articular Chondrocytes

D’Andrea, P., & Vittur, F. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.2442 · Cited by 27 · see citing works

The extracellular ATP receptor, cP2Y1, inhibits cartilage formation in micromass cultures of chick limb mesenchyme

Meyer, M. P., Swann, K., Burnstock, G., & Clarke, J. D. W. (2001) · Developmental Dynamics · doi:10.1002/dvdy.1196 · Cited by 26 · see citing works

Differential regulation of cellular maturation in chondrocytes and osteoblasts by glycine

Takahata, Y., Takarada, T., Osawa, M., Hinoi, E., Nakamura, Y., & Yoneda, Y. (2008) · Cell and Tissue Research · doi:10.1007/s00441-008-0607-7 · Cited by 22 · see citing works

Inhibition of chondrogenesis and endochondral mineralization in vitro by different calcium channel blockers.

Zimmermann, B. A., Lange, K., Mertens, P. R., & Jp, B. (1994) · PubMed · Cited by 22 · see citing works

Okadaic acid-induced inhibition of protein phosphatase 2A enhances chondrogenesis in chicken limb bud micromass cell cultures

Zákány, R., Bakó, É., Felszeghy, S., Holló, K., Balázs, M., Bárdos, H., Gergely, P., & Módis, L. (2001) · Anatomy and Embryology · doi:10.1007/s004290000128 · Cited by 20 · see citing works

PKCdelta is a positive regulator of chondrogenesis in chicken high density micromass cell cultures

Matta, C., Juhász, T., Szíjgyártó, Z., Kolozsvári, B., Somogyi, C., Nagy, G., Gergely, P., & Zákány, R. (2010) · Biochimie · doi:10.1016/j.biochi.2010.09.005 · Cited by 18 · see citing works

TRPC expression in mesenchymal stem cells

Torossian, F., Bisson, A., Vannier, J., Boyer, O., & LAMACZ, M. (2010) · Cellular & Molecular Biology Letters · doi:10.2478/s11658-010-0031-3 · Cited by 16 · see citing works

Transient receptor potential vanilloid 4 channel as an important modulator of chondrocyte mechanotransduction of osmotic loading

Hung, C. T. (2010) · Arthritis & Rheumatism · doi:10.1002/art.27617 · Cited by 14 · see citing works

Structural and histochemical aspects of the pericellular environment in cartilage

Stockwell, R. A. (1975) · Philosophical transactions of the Royal Society of London. Series B, Biological sciences · doi:10.1098/rstb.1975.0048 · Cited by 14 · see citing works

The development and nature of osteoarthritis of the hip joint.

Kh, P. (1955) · PubMed · Cited by 12 · see citing works

Electrophysiological demonstration of Na + /Ca 2+ exchange in bovine articular chondrocytes

Sánchez, J. C., Powell, T., Staines, H. M., & Wilkins, R. J. (2006) · Biorheology · doi:10.1177/0006355x2006043001005 · Cited by 11 · see citing works

Photo-Cross-Linked Scaffold with Kartogenin-Encapsulated Nanoparticles for Cartilage Regeneration

Shi, D., Xu, X., Ye, Y., Song, K., Cheng, Y., Di, J., Hu, Q., Li, J., Ju, H., Jiang, Q. Y., et al. (2016) · ACS Nano · doi:10.1021/acsnano.5b06663 · Cited by 262 · see citing works

Chondrosenescence: Definition, hallmarks and potential role in the pathogenesis of osteoarthritis

Mobasheri, A., Matta, C., Zákány, R., & Musumeci, G. (2014) · Maturitas · doi:10.1016/j.maturitas.2014.12.003 · Cited by 218 · see citing works

On the origin and impact of mesenchymal stem cell heterogeneity: new insights and emerging tools for single cell analysis

McLeod, C., & Mauck, R. L. (2017) · European Cells and Materials · doi:10.22203/ecm.v034a14 · Cited by 199 · see citing works

Enhancement of mesenchymal stem cell chondrogenesis with short-term low intensity pulsed electromagnetic fields

Parate, D., Franco‐Obregón, A., Fröhlich, J., Beyer, C., Abbas, A. A., Kamarul, T., Hui, J. H. P., & Yang, Z. (2017) · Scientific Reports · doi:10.1038/s41598-017-09892-w · Cited by 97 · see citing works

The role of chondroitin sulfate in regulating hypertrophy during MSC chondrogenesis in a cartilage mimetic hydrogel under dynamic loading

Aisenbrey, E. A., & Bryant, S. J. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.10.028 · Cited by 92 · see citing works

The chondrocyte channelome: A narrative review

Mobasheri, A., Matta, C., Uzielienè, I., Budd, E., Martı́n-Vasallo, P., & Bernotienė, E. (2018) · Joint Bone Spine · doi:10.1016/j.jbspin.2018.01.012 · Cited by 83 · see citing works

The Role of Physical Stimuli on Calcium Channels in Chondrogenic Differentiation of Mesenchymal Stem Cells

Uzielienè, I., Bernotas, P., Mobasheri, A., & Bernotienė, E. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19102998 · Cited by 76 · see citing works

Regulation of chondrogenesis by protein kinase C: Emerging new roles in calcium signalling

Matta, C., & Mobasheri, A. (2014) · Cellular Signalling · doi:10.1016/j.cellsig.2014.01.011 · Cited by 74 · see citing works

Signalling pathways in trophic skeletal development and morphogenesis: Insights from studies on teleost fish

Ahi, E. P. (2016) · Developmental Biology · doi:10.1016/j.ydbio.2016.10.003 · Cited by 65 · see citing works

Store-operated calcium entry and calcium influx via voltage-operated calcium channels regulate intracellular calcium oscillations in chondrogenic cells

Fodor, J., Matta, C., Oláh, T., Juhász, T., Takács, R., Tóth, A., Dienes, B., Csernoch, L. J., & Zákány, R. (2013) · Cell Calcium · doi:10.1016/j.ceca.2013.03.003 · Cited by 64 · see citing works

Impact of Metal Ions on Cellular Functions: A Focus on Mesenchymal Stem/Stromal Cell Differentiation

Peters, K., Staehlke, S., Rebl, H., Jonitz‐Heincke, A., & Hahn, O. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms251810127 · Cited by 63 · see citing works

Natural Polymeric Scaffolds for Tissue Engineering Applications

Ebhodaghe, S. O. (2021) · Journal of Biomaterials Science Polymer Edition · doi:10.1080/09205063.2021.1958185 · Cited by 61 · see citing works

Voltage-Dependent Calcium Channels in Chondrocytes: Roles in Health and Disease

Matta, C., Zákány, R., & Mobasheri, A. (2015) · Current Rheumatology Reports · doi:10.1007/s11926-015-0521-4 · Cited by 62 · see citing works

Transient Receptor Potential Vanilloid 5 Mediates Ca2+ Influx and Inhibits Chondrocyte Autophagy in a Rat Osteoarthritis Model

Wei, Y., Wang, Y., Wang, Y., & Bai, L. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000477387 · Cited by 55 · see citing works

Glutamate receptors in domestication and modern human evolution

O’Rourke, T., & Boeckx, C. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.10.004 · Cited by 50 · see citing works

Challenges in engineering osteochondral tissue grafts with hierarchical structures

Gadjanski, I., & Vunjak‐Novakovic, G. (2015) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2015.1070825 · Cited by 47 · see citing works

Physicochemical and Biomechanical Stimuli in Cell-Based Articular Cartilage Repair

Jahr, H., Matta, C., & Mobasheri, A. (2015) · Current Rheumatology Reports · doi:10.1007/s11926-014-0493-9 · Cited by 47 · see citing works

Repair of osteochondral defects using injectable chitosan-based hydrogel encapsulated synovial fluid-derived mesenchymal stem cells in a rabbit model

Jia, Z., Zhu, F., Li, X., Liang, Q., Zhuo, Z., Huang, J., Duan, L., Xiong, J., & Wang, D. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.01.115 · Cited by 45 · see citing works

Parental exposure to bisphenol A affects pharyngeal cartilage development and causes global transcriptomic changes in zebrafish (Danio rerio) offspring

Huang, W., Zheng, S., Xiao, J., Liu, C., Du, T., & Wu, K. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2020.126537 · Cited by 44 · see citing works

A Roadmap of In Vitro Models in Osteoarthritis: A Focus on Their Biological Relevance in Regenerative Medicine

Bartolotti, I., Roseti, L., Petretta, M., Grigolo, B., & Desando, G. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10091920 · Cited by 44 · see citing works

Preconditioning of mesenchymal stromal cells with low-intensity ultrasound: influence on chondrogenesis and directed SOX9 signaling pathways

Sahu, N., Budhiraja, G., & Subramanian, A. (2020) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1532-2 · Cited by 40 · see citing works

Long-term BPA exposure leads to bone malformation and abnormal expression of MAPK/Wnt/FoxO signaling pathway genes in zebrafish offspring

Zhu, Z., Wang, J., Cao, Q., Liu, S., Wei, W., Yang, H., & Zhang, Y. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2022.114082 · Cited by 39 · see citing works

Electrical Stimulation in Cartilage Tissue Engineering

Vaičiulevičiūtė, R., Uzielienè, I., Bernotas, P., Novickij, V., Alaburda, A., & Bernotienė, E. (2023) · Bioengineering · doi:10.3390/bioengineering10040454 · Cited by 36 · see citing works

Spontaneous calcium signaling of cartilage cells: from spatiotemporal features to biophysical modeling

Zhou, Y., Lv, M., Li, T., Zhang, T., Duncan, R. L., Wang, L., & Lu, X. L. (2019) · The FASEB Journal · doi:10.1096/fj.201801460r · Cited by 35 · see citing works

Molecular mechanisms of environmental pollutant-induced cartilage damage: from developmental disorders to osteoarthritis

Skalny, A. V., Aschner, M., Zhang, F., Guo, X., Djordjević, A. B., Sotnikova, T. I., Korobeinikova, T. V., Domingo, J. L., Farsky, S. H. P., & Tinkov, A. A. (2024) · Archives of Toxicology · doi:10.1007/s00204-024-03772-9 · Cited by 34 · see citing works

Molecular phenotyping of the surfaceome of migratory chondroprogenitors and mesenchymal stem cells using biotinylation, glycocapture and quantitative LC-MS/MS proteomic analysis

Matta, C., Boocock, D. J., Fellows, C. R., Miosge, N., Dixon, J. E., Liddell, S., Smith, J. R., & Mobasheri, A. (2019) · Scientific Reports · doi:10.1038/s41598-019-44957-y · Cited by 34 · see citing works

Shaking culture enhances chondrogenic differentiation of mouse induced pluripotent stem cell constructs

Limraksasin, P., Kosaka, Y., Zhang, M., Horie, N., Kondo, T., Okawa, H., Yamada, M., & Egusa, H. (2020) · Scientific Reports · doi:10.1038/s41598-020-72038-y · Cited by 34 · see citing works

TRPM7 channels mediate spontaneous Ca 2+ fluctuations in growth plate chondrocytes that promote bone development

Qian, N., Ichimura, A., Takei, D., Sakaguchi, R., Kitani, A., Nagaoka, R., Tomizawa, M., Miyazaki, Y., Miyachi, H., Numata, T., et al. (2019) · Science Signaling · doi:10.1126/scisignal.aaw4847 · Cited by 33 · see citing works

Recent Advances on Stimuli-Responsive Hydrogels Based on Tissue-Derived ECMs and Their Components: Towards Improving Functionality for Tissue Engineering and Controlled Drug Delivery

Serna, J. A., Rueda-Gensini, L., Céspedes-Valenzuela, D. N., Cifuentes, J., Cruz, J. C., & Muñoz-Camargo, C. (2021) · Polymers · doi:10.3390/polym13193263 · Cited by 33 · see citing works

Purinergic signalling is required for calcium oscillations in migratory chondrogenic progenitor cells

Matta, C., Fodor, J., Miosge, N., Takács, R., Juhász, T., Rybaltovszki, H., Tóth, A., Csernoch, L. J., & Zákány, R. (2014) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-014-1529-8 · Cited by 31 · see citing works

The Effect of Chemically Defined Medium on Spontaneous Calcium Signaling of In Situ Chondrocytes during Long-term Culture

Zhou, Y.-L., Park, M., Cheung, E., Wang, L., & Lu, X. (2015) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2015.02.005 · Cited by 30 · see citing works

S100A1 and S100B: Calcium Sensors at the Cross‐Roads of Multiple Chondrogenic Pathways

Diaz‐Romero, J., & Nešić, D. (2016) · Journal of Cellular Physiology · doi:10.1002/jcp.25720 · Cited by 27 · see citing works

Insulin-like Growth Factor-1 Regulates the Mechanosensitivity of Chondrocytes by Modulating TRPV4

Trompeter, N., Gardinier, J. D., DeBarros, V., Boggs, M. E., Gangadharan, V., Cain, W. J., Hurd, L., & Duncan, R. L. (2020) · Cell Calcium · doi:10.1016/j.ceca.2021.102467 · Cited by 27 · see citing works

Effect of magnetic and electric fields on plasma membrane of single cells: A computational approach

Huertas, J. F. E., Vaca‐González, J. J., Guevara, J., & Garzón–Alvarado, D. A. (2020) · Engineering Reports · doi:10.1002/eng2.12125 · Cited by 27 · see citing works

Ion channel expression and function in normal and osteoarthritic human synovial fluid progenitor cells

Bertram, K. L., Banderali, U., Tailor, P., & Krawetz, R. J. (2015) · Channels · doi:10.1080/19336950.2015.1116652 · Cited by 25 · see citing works

Continuous Passive Motion following Cartilage Surgery: Does a Common Protocol Exist?

Karnes, J. M., Harris, J. D., Griesser, M. J., & Flanigan, D. C. (2013) · The Physician and Sportsmedicine · doi:10.3810/psm.2013.11.2036 · Cited by 23 · see citing works

Ser/Thr-phosphoprotein phosphatases in chondrogenesis: neglected components of a two-player game

Matta, C., Mobasheri, A., Gergely, P., & Zákány, R. (2014) · Cellular Signalling · doi:10.1016/j.cellsig.2014.06.013 · Cited by 21 · see citing works

Transient Receptor Potential Channel, Vanilloid 5, Induces Chondrocyte Apoptosis in a Rat Osteoarthritis Model Through the Mediation of Ca2+ Influx

Wei, Y., Zheng, D., Guo, X., Zhao, M., Gao, L., & Bai, L. (2018) · Cellular Physiology and Biochemistry · doi:10.1159/000488725 · Cited by 21 · see citing works

PFOA and PFOS are associated with reduced expression of the parathyroid hormone 2 receptor (PTH2R) gene in women

Galloway, T. S., Fletcher, T., Thomas, O. J., Lee, B. P., Pilling, L. C., & Harries, L. W. (2014) · Chemosphere · doi:10.1016/j.chemosphere.2014.09.066 · Cited by 19 · see citing works

In Vitro Evaluation of the Effect of Stimulation with Magnetic Fields on Chondrocytes

Huertas, J. F. E., Vaca‐González, J. J., Guevara, J., Vega, J. F., Hata, Y., & Garzón–Alvarado, D. A. (2019) · Bioelectromagnetics · doi:10.1002/bem.22231 · Cited by 17 · see citing works

N-methyl-D-aspartate (NMDA) receptor expression and function is required for early chondrogenesis

Matta, C., Juhász, T., Fodor, J., Hajdú, T., Katona, É., Szűcs-Somogyi, C., Takács, R., Vágó, J., Oláh, T., Bartók, Á., et al. (2019) · Cell Communication and Signaling · doi:10.1186/s12964-019-0487-3 · Cited by 18 · see citing works

Bioenergetic-active hydrogel drives extracellular matrix synthesis for cartilage repair

Jiang, S., Lan, Z., Zhong, Z., Liu, X., Xu, J. B., Chen, Y., Li, J., Chen, C., Liu, D., Chen, M., et al. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.07.043 · Cited by 16 · see citing works

The effect of silk–gelatin bioink and TGF-β3 on mesenchymal stromal cells in 3D bioprinted chondrogenic constructs: A proteomic study

Chawla, S., Desando, G., Gabusi, E., Sharma, A., Trucco, D., Chakraborty, J., Manferdini, C., Petretta, M., Lisignoli, G., & Ghosh, S. (2021) · Journal of materials research/Pratt's guide to venture capital sources · doi:10.1557/s43578-021-00230-5 · Cited by 15 · see citing works

Biophysical control of plasticity and patterning in regeneration and cancer

Murugan, N. J., Cariba, S., Abeygunawardena, S., Rouleau, N., & Payne, S. L. (2023) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-023-05054-6 · Cited by 13 · see citing works

Microniche geometry modulates the mechanical properties and calcium signaling of chondrocytes

Zhang, Q., Bai, J.-D., Wu, X., Liu, X., Zhang, M., & Chen, W. (2020) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2020.109729 · Cited by 14 · see citing works

Stimulation of Chondrocyte and Bone Marrow Mesenchymal Stem Cell Chondrogenic Response by Polypyrrole and Polypyrrole/Gold Nanoparticles

Uzielienè, I., Popov, A., Lisytė, V., Kugaudaite, G., Bialaglovyte, P., Vaičiulevičiūtė, R., Kvederas, G., Bernotienė, E., & Ramanavičienė, A. (2023) · Polymers · doi:10.3390/polym15112571 · Cited by 13 · see citing works

Targeted Gq-GPCR activation drives ER-dependent calcium oscillations in chondrocytes

McDonough, R. C., Gilbert, R. M., Gleghorn, J. P., & Price, C. (2021) · Cell Calcium · doi:10.1016/j.ceca.2021.102363 · Cited by 12 · see citing works

Transcriptome‐based screening of ion channels and transporters in a migratory chondroprogenitor cell line isolated from late‐stage osteoarthritic cartilage

Matta, C., Lewis, R., Fellows, C. R., Diszházi, G., Almássy, J., Miosge, N., Dixon, J. E., Uribe, M. C., May, S. T., Póliska, S., et al. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30413 · Cited by 13 · see citing works

Dissection of the molecular targets and signaling pathways of Guzhi Zengsheng Zhitongwan based on the analysis of serum proteomics

Yao, B., Liu, J., Xu, D., Pan, D., Zhang, M., Zhao, D., & Leng, X. (2019) · Chinese Medicine · doi:10.1186/s13020-019-0252-y · Cited by 11 · see citing works

Purinergic signalling-evoked intracellular Ca2+ concentration changes in the regulation of chondrogenesis and skeletal muscle formation

Matta, C., Fodor, J., Csernoch, L. J., & Zákány, R. (2016) · Cell Calcium · doi:10.1016/j.ceca.2016.01.006 · Cited by 11 · see citing works

The Effect of CaV1.2 Inhibitor Nifedipine on Chondrogenic Differentiation of Human Bone Marrow or Menstrual Blood-Derived Mesenchymal Stem Cells and Chondrocytes

Uzielienè, I., Bironaitė, D., Mikšiūnas, R., Bagdonas, E., Vaičiulevičiūtė, R., Mobasheri, A., & Bernotienė, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076730 · Cited by 10 · see citing works

Combining Piezoelectric Stimulation and Extracellular Vesicles for Cartilage Regeneration

Lai, C., Jin, F., Feng, Z., Zhang, R., Yuan, M., Qian, L., Zhang, L., Wang, Y., & Zhao, J. (2023) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1155/2023/5539194 · Cited by 8 · see citing works

Resveratrol‐Loaded Poly( d , l ‐Lactide‐Co‐Glycolide) Microspheres Integrated in a Hyaluronic Acid Injectable Hydrogel for Cartilage Regeneration

Wang, X., Li, X., Duffy, P. E., McMahon, S., Wang, X., Lyu, J., Xu, Q., Sigen, A., Chen, N. N., Bi, V., et al. (2021) · Advanced NanoBiomed Research · doi:10.1002/anbr.202100070 · Cited by 8 · see citing works

Ca2+-Activated K+ Channels in Progenitor Cells of Musculoskeletal Tissues: A Narrative Review

Takács, R., Kovács, P., Mansour, E. R. A., Almássy, J., Fodor, J., Ducza, L., Barrett‐Jolley, R., Lewis, R., & Matta, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076796 · Cited by 8 · see citing works

Targeted Activation of G-Protein Coupled Receptor-Mediated Ca 2+ Signaling Drives Enhanced Cartilage-Like Matrix Formation

McDonough, R. C., & Price, C. (2021) · Tissue Engineering Part A · doi:10.1089/ten.tea.2021.0078 · Cited by 6 · see citing works

DREADD‐based synthetic control of chondrocyte calcium signaling in vitro

McDonough, R. C., Shoga, J. S., & Price, C. (2019) · Journal of Orthopaedic Research® · doi:10.1002/jor.24285 · Cited by 6 · see citing works

Molecular roles in membrane receptor signaling pathways and cascade reactions in chondrocytes: a review

Zhu, Y., Zhu, J., Wang, X., Wang, P., & Liu, R. (2025) · Journal of Molecular Histology · doi:10.1007/s10735-025-10368-9 · Cited by 4 · see citing works

The Effect of TGF-β3 and IL-1β on L-Type Voltage-Operated Calcium Channels and Calcium Ion Homeostasis in Osteoarthritic Chondrocytes and Human Bone Marrow-Derived Mesenchymal Stem Cells During Chondrogenesis

Shelest, A., Alaburda, A., Vaičiulevičiūtė, R., Uzielienè, I., Bialaglovyte, P., & Bernotienė, E. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17030343 · Cited by 4 · see citing works

Calcium signaling dysregulation in rheumatoid arthritis: a comparative perspective with osteoarthritis

Nguyen, T. D., Abreu, H., Tommasi, N. D., Azzarone, L., Martino, R. M. C. D., Riva, B., Raineri, D., Pirali, T., Chiocchetti, A., & Cappellano, G. (2025) · Autoimmunity Reviews · doi:10.1016/j.autrev.2025.103923 · Cited by 3 · see citing works

Bupivacaine in combination with sildenafil (Viagra) and vitamin D3 have anti-inflammatory effects in osteoarthritic chondrocytes

Hansson, E., & Skiöldebrand, E. (2021) · Current Research in Pharmacology and Drug Discovery · doi:10.1016/j.crphar.2021.100066 · Cited by 3 · see citing works

A novel modified culture medium for enhancing redifferentiation of chondrocytes for cartilage tissue engineering applications

Sonthithai, P., Hankamolsiri, W., Lertwimol, T., Uppanan, P., & Janvikul, W. (2022) · Biotechnology Progress · doi:10.1002/btpr.3240 · Cited by 2 · see citing works

Stem Cells in Bone and Articular Cartilage Tissue Regeneration

Fellows, C. R., Gauthaman, K., Pushparaj, P. N., Abbas, M. M., Matta, C., Lewis, R., Buhrmann, C., Shakibaei, M., & Mobasheri, A. (2016) · Stem cells in clinical applications · doi:10.1007/978-3-319-40144-7_9 · Cited by 2 · see citing works

Impact of Mechanobiological Perturbation in Cartilage Tissue Engineering

Yang, Z., Wu, Y., Yin, L., & Lee, E. H. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816390-0.00019-4 · Cited by 2 · see citing works

Piezoelectric Biomaterials for Osteochondral Tissue Engineering: Advances, Mechanisms, and Translational Prospects

Wang, H., & Li, Y. (2026) · Journal of Functional Biomaterials · doi:10.3390/jfb17040173 · Cited by 1 · see citing works

Alginate Hydrogels for the 3D Culture and Therapeutic Delivery of Cells

Wright, B., & Connon, C. J. (2014) · Royal Society of Chemistry eBooks · doi:10.1039/9781782622055-00135 · Cited by 1 · see citing works

Mechanobiology regulation

McEvoy, E., & McNamara, L. M. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-91821-3.00007-4 · Cited by 1 · see citing works

Feasibility of intra-articular adeno-associated virus-mediated proteoglycan-4 gene therapy to prevent osteoarthritis

Choe, H. H., Lim, T. H., Pedersen, D., Grosland, N. M., Salem, A. K., & Martin, J. A. (2015) · doi:10.17077/etd.jugvpuoe

Bioengineering Human Scaffold-free Cartilage Constructs Using Paediatric Auricular Tissue

Akbari, P. (2015) · TSpace (University of Toronto)

Le « channelome » du chondrocyte. Revue narrative

Mobasheri, A., Matta, C., Uzielienè, I., Budd, E., Martı́n-Vasallo, P., & Bernotienė, E. (2018) · Revue du Rhumatisme · doi:10.1016/j.rhum.2018.08.001

Ectodysplasin-A (EDA) Signaling Cross-Talk in Skeletogenesis

Ahi, E. P., Moustakas-Verho, J. E., & Singh, P. (2026) · Calcified Tissue International · doi:10.1007/s00223-026-01502-0 · Cited by 1 · see citing works

Développement et caractérisation d'hydrogels d'acide hyaluronique auto-réticulants injectables en ingénierie tissulaire du squelette

Flégeau, K. (2019) · theses.fr (ABES) · doi:10.70675/883d99f3z556az4130z9194z5fa38b59e61c

Decellularized matrix scaffold integrating hyaluronic acid-celecoxib modulates inflammation and promotes regenerative meniscus remodeling

Ding, Y., Zhang, H., Cai, P., Xiao, Y., Cui, J., Song, J., Lu, C., Sun, B., Mo, X., Lin, H., et al. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124270

Single and combined nanotoxicity of titanium dioxide and cadmium: implications for skeletal and behavioral development in zebrafish

Castro, C., Mamboungou, J., Qualhato, G., Cirqueira, F., Rocha, T. L., & Vieira, L. G. (2026) · Environmental Science and Pollution Research · doi:10.1007/s11356-026-38005-2

Functionality of voltage-gated ion channels: influence of cytokines and genetic variation

Shelest, A. (2026) · doi:10.15388/vu.thesis.964

Signaling pathways in endochondral ossification: Implication for cartilage tissue engineering

Panjaitan, S. Y., & Pawitan, J. (2012) · Biochemistry : an Indian journal · Cited by 1 · see citing works

The Role of Physical Stimuli on Calcium Channels in Chondrogenic Differentiation of Mesenchymal Stem Cells

Uzielienè, I., Bernotas, P., Mobasheri, A., & Bernotienė, E. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19102998 · Cited by 76 · see citing works

Soluble Signalling Factors Derived from Differentiated Cartilage Tissue Affect Chondrogenic Differentiation of Rat Adult Marrow Stromal Cells

Ahmed, N., Dreier, R., Göpferich, A. M., Grifka, J. K., & Grässel, S. (2007) · Cellular Physiology and Biochemistry · doi:10.1159/000107728 · Cited by 88 · see citing works

Genetic Manipulation of Calcium Release-Activated Calcium Channel 1 Modulates the Multipotency of Human Cartilage-Derived Mesenchymal Stem Cells

Liu, S., Takahashi, M., Kiyoi, T., Toyama, K., & Mogi, M. (2019) · Journal of Immunology Research · doi:10.1155/2019/7510214 · Cited by 11 · see citing works

Intracellular calcium levels in human mesenchymal stem cells isolated from bone marrow and menstrual blood as a modulator of chondrogenic differentiation

Uzielienè, I., Bernotienė, E., Rakauskiene, G., Sadauskaite, E., Bagdonas, E., Alaburda, A., Kvederas, G., & Mobasheri, A. (2020) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2020.02.161